Advanced search
Publication Cover
Molecular and Cellular Biology Volume 25, 2005 - Issue 11
Submit an article Journal homepage
72
Views
134
CrossRef citations to date
0
Altmetric
Chromosome Structure and Dynamics

In Vivo HP1 Targeting Causes Large-Scale Chromatin Condensation and Enhanced Histone Lysine Methylation

Pernette J. Verschure1 Swammerdam Institute for Life Sciences, BioCentrum Amsterdam, University of Amsterdam, Kruislaan 318, 1098 SMAmsterdam, The NetherlandsCorrespondence[email protected]
,
Ineke van der Kraan1 Swammerdam Institute for Life Sciences, BioCentrum Amsterdam, University of Amsterdam, Kruislaan 318, 1098 SMAmsterdam, The Netherlands
,
Wim de Leeuw2 Center for Mathematics and Computer Science, CWI, 1090 GBAmsterdam, The Netherlands
,
Johan van der Vlag3 Nephrology Research Lab, Nijmegen Center for Molecular Life Sciences, Division of Nephrology, University Medical Center, Nijmegen, The Netherlands
,
Anne E. Carpenter4 Department of Cell and Structural Biology, University of Illinois, Urbana-Champaign, Urbana, Illinois61801
,
Andrew S. Belmont4 Department of Cell and Structural Biology, University of Illinois, Urbana-Champaign, Urbana, Illinois61801
&
Roel van Driel1 Swammerdam Institute for Life Sciences, BioCentrum Amsterdam, University of Amsterdam, Kruislaan 318, 1098 SMAmsterdam, The Netherlands
 show all
Pages 4552-4564 | Received 05 Dec 2004, Accepted 22 Feb 2005, Published online: 27 Mar 2023

Citations (134)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

V.B. Fedoseyeva & A.A. Alexandrov. (2014) Large-scale periodicity of nucleosome positioning signal in pericentric regions of chromosomes (Drosophila melanogaster). Journal of Biomolecular Structure and Dynamics 32:12, pages 2042-2050.
Read now
Maciej Meglicki, Marta Teperek-Tkacz & Ewa Borsuk. (2012) Appearance and heterochromatin localization of HP1α in early mouse embryos depends on cytoplasmic clock and H3S10 phosphorylation. Cell Cycle 11:11, pages 2189-2205.
Read now
Artem K. Velichko, Omar L. Kantidze & Sergey V. Razin. (2011) HP1α is not necessary for the structural maintenance of centromeric heterochromatin. Epigenetics 6:3, pages 380-387.
Read now
Philip G. Wong, Michele A. Glozak, Thinh V. Cao, Cyrus Vaziri, Edward Seto & Mark G. Alexandrow. (2010) Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin . Cell Cycle 9:21, pages 4351-4363.
Read now
Christoffel Dinant & Martijn S. Luijsterburg. (2009) The Emerging Role of HP1 in the DNA Damage Response. Molecular and Cellular Biology 29:24, pages 6335-6340.
Read now
Sandra Goetze, Julio Mateos-Langerak, Hinco J. Gierman, Wim de Leeuw, Osdilly Giromus, Mireille H. G. Indemans, Jan Koster, Vladan Ondrej, Rogier Versteeg & Roel van Driel. (2007) The Three-Dimensional Structure of Human Interphase Chromosomes Is Related to the Transcriptome Map. Molecular and Cellular Biology 27:12, pages 4475-4487.
Read now
Chunhong Yan & Douglas D. Boyd. (2006) Histone H3 Acetylation and H3 K4 Methylation Define Distinct Chromatin Regions Permissive for Transgene Expression. Molecular and Cellular Biology 26:17, pages 6357-6371.
Read now
Fangwei Wang, Naoki Koyama, Hiroko Nishida, Tokuko Haraguchi, Walter Reith & Toshiro Tsukamoto. (2006) The Assembly and Maintenance of Heterochromatin Initiated by Transgene Repeats Are Independent of the RNA Interference Pathway in Mammalian Cells. Molecular and Cellular Biology 26:11, pages 4028-4040.
Read now

Articles from other publishers (126)

Katerina Cermakova & H. Courtney Hodges. (2023) Interaction modules that impart specificity to disordered protein. Trends in Biochemical Sciences 48:5, pages 477-490.
Crossref
John M. Schoelz & Nicole C. Riddle. (2022) Functions of HP1 proteins in transcriptional regulation. Epigenetics & Chromatin 15:1.
Crossref
Achal Mahajan, Wen Yan, Alexandra Zidovska, David Saintillan & Michael J. Shelley. (2022) Euchromatin Activity Enhances Segregation and Compaction of Heterochromatin in the Cell Nucleus. Physical Review X 12:4.
Crossref
Bradley J. Lukasak, Michelle M. Mitchener, Lingchun Kong, Barbara E. Dul, Cole D. Lazarus, Aarthi Ramakrishnan, Jizhi Ni, Li Shen, Ian Maze & Tom W. Muir. (2022) TGM2-mediated histone transglutamination is dictated by steric accessibility. Proceedings of the National Academy of Sciences 119:43.
Crossref
Wen‐Ting Chu, Xiakun Chu & Jin Wang. (2022) Uncovering the Quantitative Relationships Among Chromosome Fluctuations, Epigenetics, and Gene Expressions of Transdifferentiation on Waddington Landscape. Advanced Science 9:10, pages 2103617.
Crossref
Sandra Nhim, Sylvie Gimenez, Rima Nait-Saidi, Dany Severac, Kiwoong Nam, Emmanuelle d'Alençon & Nicolas Nègre. (2022) H3K9me2 genome-wide distribution in the holocentric insect Spodoptera frugiperda (Lepidoptera: Noctuidae). Genomics 114:1, pages 384-397.
Crossref
Ziheng Zhang, Ping Wang & Ji-Long Liu. 2022. CRISPR. CRISPR 1 22 .
Jia-Yi Hou, Lan Zhou, Jia-Lei Li, De-Ping Wang & Ji-Min Cao. (2021) Emerging roles of non-histone protein crotonylation in biomedicine. Cell & Bioscience 11:1.
Crossref
Joseph G. Wakim, Sarah H. Sandholtz & Andrew J. Spakowitz. (2021) Impact of chromosomal organization on epigenetic drift and domain stability revealed by physics-based simulations. Biophysical Journal 120:22, pages 4932-4943.
Crossref
Hui Jiang, Patrycja Swacha & Nelson O. Gekara. (2021) Nuclear AIM2‐Like Receptors Drive Genotoxic Tissue Injury by Inhibiting DNA Repair. Advanced Science 8:22, pages 2102534.
Crossref
Yuchen Gao, Mengting Han, Stephen Shang, Haifeng Wang & Lei S. Qi. (2021) Interrogation of the dynamic properties of higher-order heterochromatin using CRISPR-dCas9. Molecular Cell 81:20, pages 4287-4299.e5.
Crossref
Amy R Strom, Ronald J Biggs, Edward J Banigan, Xiaotao Wang, Katherine Chiu, Cameron Herman, Jimena Collado, Feng Yue, Joan C Ritland Politz, Leah J Tait, David Scalzo, Agnes Telling, Mark Groudine, Clifford P Brangwynne, John F Marko & Andrew D Stephens. (2021) HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics. eLife 10.
Crossref
Sy Redding. (2021) Dynamic asymmetry and why chromatin defies simple physical definitions. Current Opinion in Cell Biology 70, pages 116-122.
Crossref
Munender Vodnala, Eun-Bee Choi & Yick W Fong. (2021) Low complexity domains, condensates, and stem cell pluripotency. World Journal of Stem Cells 13:5, pages 416-438.
Crossref
Didier Fesquet, David Llères, Charlotte Grimaud, Cristina Viganò, Francisca Méchali, Séverine Boulon, Olivier Coux, Catherine Bonne-Andrea & Véronique Baldin. (2021) The 20S proteasome activator PA28γ controls the compaction of chromatin. Journal of Cell Science 134:3.
Crossref
Muneaki Nakamura, Yuchen Gao, Antonia A. Dominguez & Lei S. Qi. (2021) CRISPR technologies for precise epigenome editing. Nature Cell Biology 23:1, pages 11-22.
Crossref
Bhavatharini Kasinathan, Serafin U ColmenaresIIIIII, Hannah McConnell, Janet M Young, Gary H Karpen & Harmit S Malik. (2020) Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. eLife 9.
Crossref
Sarah H. Sandholtz, Deepti Kannan, Bruno G. Beltran & Andrew J. Spakowitz. (2020) Chromosome Structural Mechanics Dictates the Local Spreading of Epigenetic Marks. Biophysical Journal 119:8, pages 1630-1639.
Crossref
Sarah H. Sandholtz, Quinn MacPhersonAndrew J. Spakowitz. (2020) Physical modeling of the heritability and maintenance of epigenetic modifications. Proceedings of the National Academy of Sciences 117:34, pages 20423-20429.
Crossref
C A Brackley. (2020) Polymer compaction and bridging-induced clustering of protein-inspired patchy particles. Journal of Physics: Condensed Matter 32:31, pages 314002.
Crossref
Guang Shi, Yang Hu, Xing Zhu, Yuanling Jiang, Junjie Pang, Chuanle Wang, Wenjun Huang, Yong Zhao, Wenbin Ma, Dan Liu, Junjiu Huang & Zhou Songyang. (2020) A critical role of telomere chromatin compaction in ALT tumor cell growth. Nucleic Acids Research 48:11, pages 6019-6031.
Crossref
Erica M. Hildebrand & Job Dekker. (2020) Mechanisms and Functions of Chromosome Compartmentalization. Trends in Biochemical Sciences 45:5, pages 385-396.
Crossref
Sandro Baldi, Philipp Korber & Peter B. Becker. (2020) Beads on a string—nucleosome array arrangements and folding of the chromatin fiber. Nature Structural & Molecular Biology 27:2, pages 109-118.
Crossref
Imke K. Mandemaker, Di Zhou, Serena T. Bruens, Dick H. Dekkers, Pernette J. Verschure, Raghu R. Edupuganti, Eran Meshorer, Jeroen A. Demmers & Jurgen A. Marteijn. (2020) Histone H1 eviction by the histone chaperone SET reduces cell survival following DNA damage. Journal of Cell Science.
Crossref
Boris Slobodin. 2020. Rheumatic Disease in Geriatrics. Rheumatic Disease in Geriatrics 17 28 .
Andrew J. Spakowitz. (2019) Polymer physics across scales: Modeling the multiscale behavior of functional soft materials and biological systems. The Journal of Chemical Physics 151:23, pages 230902.
Crossref
S. A. Grigoryev & E. Y. Popova. (2019) Attraction of Likenesses: Mechanisms of Self-Association and Compartmentalization of Eukaryotic Chromatin. Molecular Biology 53:6, pages 820-837.
Crossref
Sarah H Sandholtz, Bruno G Beltran & Andrew J Spakowitz. (2019) Physical modeling of the spreading of epigenetic modifications through transient DNA looping. Journal of Physics A: Mathematical and Theoretical 52:43, pages 434001.
Crossref
Iuliia Boichenko & Beat Fierz. (2019) Chemical and biophysical methods to explore dynamic mechanisms of chromatin silencing. Current Opinion in Chemical Biology 51, pages 1-10.
Crossref
Brandon D. Fields & Scott Kennedy. (2019) Chromatin Compaction by Small RNAs and the Nuclear RNAi Machinery in C. elegans. Scientific Reports 9:1.
Crossref
Saima Akram, Fengrui Yang, Junying Li, Gregory Adams, Yingying Liu, Xiaoxuan Zhuang, Lingluo Chu, Xu Liu, Nerimah Emmett, Winston Thompson, McKay Mullen, Saravana Muthusamy, Wenwen Wang, Fei Mo & Xing Liu. (2018) LRIF1 interacts with HP1 α to coordinate accurate chromosome segregation during mitosis . Journal of Molecular Cell Biology 10:6, pages 527-538.
Crossref
Aniek Janssen, Serafin U. Colmenares & Gary H. Karpen. (2018) Heterochromatin: Guardian of the Genome. Annual Review of Cell and Developmental Biology 34:1, pages 265-288.
Crossref
Elisa Dultz, Roberta Mancini, Guido Polles, Pascal Vallotton, Frank Alber & Karsten Weis. (2018) Quantitative imaging of chromatin decompaction in living cells. Molecular Biology of the Cell 29:14, pages 1763-1777.
Crossref
Maurizio Bruschi, Andrea Petretto, Augusto Vaglio, Laura Santucci, Giovanni Candiano & Gian Ghiggeri. (2018) Annexin A1 and Autoimmunity: From Basic Science to Clinical Applications. International Journal of Molecular Sciences 19:5, pages 1348.
Crossref
Adam G. Larson & Geeta J. Narlikar. (2018) The Role of Phase Separation in Heterochromatin Formation, Function, and Regulation. Biochemistry 57:17, pages 2540-2548.
Crossref
Laia Bosch-Presegué, Helena Raurell-Vila, Joshua K. Thackray, Jessica González, Carmen Casal, Noriko Kane-Goldsmith, Miguel Vizoso, Jeremy P. Brown, Antonio Gómez, Juan Ausió, Timo Zimmermann, Manel Esteller, Gunnar Schotta, Prim B. Singh, Lourdes Serrano & Alejandro Vaquero. (2017) Mammalian HP1 Isoforms Have Specific Roles in Heterochromatin Structure and Organization. Cell Reports 21:8, pages 2048-2057.
Crossref
Teresa Pankert, Thibaud Jegou, Maïwen Caudron-Herger & Karsten Rippe. (2017) Tethering RNA to chromatin for fluorescence microscopy based analysis of nuclear organization. Methods 123, pages 89-101.
Crossref
Wei Wei, Anqi Mao, Bin Tang, Qiufang Zeng, Shennan Gao, Xiaoguang Liu, Lu Lu, Wenpeng Li, James X. Du, Jiwen Li, Jiemin Wong & Lujian Liao. (2017) Large-Scale Identification of Protein Crotonylation Reveals Its Role in Multiple Cellular Functions. Journal of Proteome Research 16:4, pages 1743-1752.
Crossref
Fan Yao, FangTing Li & TieJun Li. (2016) Mean field study of a propagation-turnover lattice model for the dynamics of histone marking. Science China Physics, Mechanics & Astronomy 60:2.
Crossref
Maurizio Bruschi, Andrea Petretto, Roberta Bertelli, Maricla Galetti, Alice Bonanni, Federico Pratesi, Paola Migliorini, Giovanni Candiano, Augusto Vaglio & Gian Marco Ghiggeri. (2017) Post-translational modified proteins are biomarkers of autoimmune-processes: NETosis and the inflammatory–autoimmunity connection. Clinica Chimica Acta 464, pages 12-16.
Crossref
Rossana Piccinno, Marta Cipinska & Vassilis Roukos. 2017. ATM Kinase. ATM Kinase 263 275 .
Laura Brueckner, Joris van Arensbergen, Waseem Akhtar, Ludo Pagie & Bas van Steensel. (2016) High-throughput assessment of context-dependent effects of chromatin proteins. Epigenetics & Chromatin 9:1.
Crossref
Phillip M. Pifer, Joshua C. Farris, Alyssa L. Thomas, Peter Stoilov, James Denvir, David M. Smith & Steven M. Frisch. (2016) Grainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial–mesenchymal transition. Molecular Biology of the Cell 27:15, pages 2479-2492.
Crossref
Kyoko Hiragami-Hamada, Szabolcs Soeroes, Miroslav Nikolov, Bryan Wilkins, Sarah Kreuz, Carol Chen, Inti A. De La Rosa-Velázquez, Hans Michael Zenn, Nils Kost, Wiebke Pohl, Aleksandar Chernev, Dirk Schwarzer, Thomas Jenuwein, Matthew Lorincz, Bastian Zimmermann, Peter Jomo Walla, Heinz Neumann, Tuncay Baubec, Henning Urlaub & Wolfgang Fischle. (2016) Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin. Nature Communications 7:1.
Crossref
Liron Even-Faitelson, Vahideh Hassan-Zadeh, Zahra Baghestani & David P. Bazett-Jones. (2015) Coming to terms with chromatin structure. Chromosoma 125:1, pages 95-110.
Crossref
Lise Rivière, Laetitia Gerossier, Aurélie Ducroux, Sarah Dion, Qiang Deng, Marie-Louise Michel, Marie-Annick Buendia, Olivier Hantz & Christine Neuveut. (2015) HBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase. Journal of Hepatology 63:5, pages 1093-1102.
Crossref
Sarah Osterwald, Katharina I. Deeg, Inn Chung, Daniel Parisotto, Stefan Wörz, Karl Rohr, Holger Erfle & Karsten Rippe. (2015) PML induces compaction, TRF2 depletion and DNA damage signaling at telomeres and promotes their alternative lengthening. Journal of Cell Science 128:10, pages 1887-1900.
Crossref
Peter J Mulligan, Elena F Koslover & Andrew J Spakowitz. (2015) Thermodynamic model of heterochromatin formation through epigenetic regulation. Journal of Physics: Condensed Matter 27:6, pages 064109.
Crossref
Gita Kumari & Ranjan Sen. 2015. Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci. Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci 41 92 .
Sergiy Borysov, Victoria L. Bryant & Mark G. Alexandrow. 2015. Chromatin Protocols. Chromatin Protocols 289 303 .
Sunwha Cho, Jung Sun Park & Yong-Kook Kang. (2014) AGO2 and SETDB1 cooperate in promoter-targeted transcriptional silencing of the androgen receptor gene. Nucleic Acids Research 42:22, pages 13545-13556.
Crossref
Rahul Bharadwaj, Cyril J. Peter, Yan Jiang, Panos Roussos, Annie Vogel-Ciernia, Erica Y. Shen, Amanda C. Mitchell, Wenjie Mao, Catheryne Whittle, Aslihan Dincer, Mira Jakovcevski, Venu Pothula, Theodore P. Rasmussen, Stella G. Giakoumaki, Panos Bitsios, Ajfar Sherif, Paul D. Gardner, Patricia Ernst, Subroto Ghose, Pamela Sklar, Vahram Haroutunian, Carol Tamminga, Richard H. Myers, Kensuke Futai, Marcelo A. Wood & Schahram Akbarian. (2014) Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition. Neuron 84:5, pages 997-1008.
Crossref
Rebecca C. Burgess, Bharat Burman, Michael J. Kruhlak & Tom Misteli. (2014) Activation of DNA Damage Response Signaling by Condensed Chromatin. Cell Reports 9:5, pages 1703-1717.
Crossref
Roberto Ferrari, Dawei Gou, Gauri Jawdekar, Sarah A. Johnson, Miguel Nava, Trent Su, Ahmed F. Yousef, Nathan R. Zemke, Matteo Pellegrini, Siavash K. Kurdistani & Arnold J. Berk. (2014) Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection. Cell Host & Microbe 16:5, pages 663-676.
Crossref
Oliver Weth, Christine Paprotka, Katharina Günther, Astrid Schulte, Manuel Baierl, Joerg Leers, Niels Galjart & Rainer Renkawitz. (2014) CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin. Nucleic Acids Research 42:19, pages 11941-11951.
Crossref
Vassilis Roukos, Rebecca C Burgess & Tom Misteli. (2014) Generation of cell-based systems to visualize chromosome damage and translocations in living cells. Nature Protocols 9:10, pages 2476-2492.
Crossref
Lingluo Chu, Yuda Huo, Xing Liu, Phil Yao, Kelwyn Thomas, Hao Jiang, Tongge Zhu, Guanglan Zhang, Maryam Chaudhry, Gregory Adams, Winston Thompson, Zhen Dou, Changjiang Jin, Ping He & Xuebiao Yao. (2014) The Spatiotemporal Dynamics of Chromatin Protein HP1α Is Essential for Accurate Chromosome Segregation during Cell Division. Journal of Biological Chemistry 289:38, pages 26249-26262.
Crossref
Alessio Maiolica, Maria de Medina-Redondo, Erwin M. Schoof, Apirat Chaikuad, Fabrizio Villa, Marco Gatti, Siva Jeganathan, Hua Jane Lou, Karel Novy, Simon Hauri, Umut H. Toprak, Franz Herzog, Patrick Meraldi, Lorenza Penengo, Benjamin E. Turk, Stefan Knapp, Rune Linding & Ruedi Aebersold. (2014) Modulation of the Chromatin Phosphoproteome by the Haspin Protein Kinase. Molecular & Cellular Proteomics 13:7, pages 1724-1740.
Crossref
В.Б. Федосеева & V.B. Fedoseyeva. (2014) Theoretical Estimation of Nucleosome Density for Gene Sequences of Different Orthologs upon Euchromatic and Heterochromatic Locations. Математическая биология и биоинформатика Mathematical Biology and Bioinformatics 9:1, pages 273-285.
Crossref
Sajad H. Ahanger, Katharina Günther, Oliver Weth, Marek Bartkuhn, Ramesh R. Bhonde, Yogesh S. Shouche & Rainer Renkawitz. (2014) Ectopically tethered CP190 induces large-scale chromatin decondensation. Scientific Reports 4:1.
Crossref
Lori L. Wallrath, Michael W. Vitalini & Sarah C. R. Elgin. 2014. Fundamentals of Chromatin. Fundamentals of Chromatin 529 552 .
Adam Blattler & Peggy J. Farnham. (2013) Cross-talk between Site-specific Transcription Factors and DNA Methylation States. Journal of Biological Chemistry 288:48, pages 34287-34294.
Crossref
Thi B. Trinh, Qing Xiao & Dehua Pei. (2013) Profiling the Substrate Specificity of Protein Kinases by On-Bead Screening of Peptide Libraries. Biochemistry 52:33, pages 5645-5655.
Crossref
Maartje C. Brink, Diewertje G. E. Piebes, Marloes L. de Groote, Martijn S. Luijsterburg, Corella S. Casas-Delucchi, Roel van Driel, Marianne G. Rots, M. Cristina Cardoso & Pernette J. Verschure. (2013) A Role for MeCP2 in Switching Gene Activity via Chromatin Unfolding and HP1γ Displacement. PLoS ONE 8:7, pages e69347.
Crossref
Katharina Günther, Mareike Rust, Joerg Leers, Thomas Boettger, Maren Scharfe, Michael Jarek, Marek Bartkuhn & Rainer Renkawitz. (2013) Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences. Nucleic Acids Research 41:5, pages 3010-3021.
Crossref
Dong Yang, Zhanfu Ma, Weiran Lin, Juntao Yang, Chunyan Tian, Handong Wei, Ying Jiang & Fuchu He. (2013) Identification of KAP-1-associated complexes negatively regulating the Ey and β-major globin genes in the β-globin locus. Journal of Proteomics 80, pages 132-144.
Crossref
Peter Nestorov, Mathieu Tardat & Antoine H.F.M. Peters. 2013. Epigenetics and Development. Epigenetics and Development 243 291 .
M. L. de Groote, P. J. Verschure & M. G. Rots. (2012) Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes. Nucleic Acids Research 40:21, pages 10596-10613.
Crossref
Francesca Munari, Szabolcs Soeroes, Hans Michael Zenn, Adrian Schomburg, Nils Kost, Sabrina Schröder, Rebecca Klingberg, Nasrollah Rezaei-Ghaleh, Alexandra Stützer, Kathy Ann Gelato, Peter Jomo Walla, Stefan Becker, Dirk Schwarzer, Bastian Zimmermann, Wolfgang Fischle & Markus Zweckstetter. (2012) Methylation of Lysine 9 in Histone H3 Directs Alternative Modes of Highly Dynamic Interaction of Heterochromatin Protein hHP1β with the Nucleosome. Journal of Biological Chemistry 287:40, pages 33756-33765.
Crossref
Courtney Hodges & Gerald R. Crabtree. (2012) Dynamics of inherently bounded histone modification domains. Proceedings of the National Academy of Sciences 109:33, pages 13296-13301.
Crossref
Nathaniel A. Hathaway, Oliver Bell, Courtney Hodges, Erik L. Miller, Dana S. Neel & Gerald R. Crabtree. (2012) Dynamics and Memory of Heterochromatin in Living Cells. Cell 149:7, pages 1447-1460.
Crossref
Martijn S Luijsterburg, Klara Acs, Leena Ackermann, Wouter W Wiegant, Simon Bekker-Jensen, Dorthe H Larsen, Kum Kum Khanna, Haico van Attikum, Niels Mailand & Nico P Dantuma. (2012) A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. The EMBO Journal 31:11, pages 2511-2527.
Crossref
Karsten Rippe, Rene Stehr & Gero Wedemann. 2012. Innovations in Biomolecular Modeling and Simulations. Innovations in Biomolecular Modeling and Simulations 198 235 .
H. Mitsunobu, M. Izumi, H. Mon, T. Tatsuke, J. M. Lee & T. Kusakabe. (2012) Molecular characterization of heterochromatin proteins 1a and 1b from the silkworm, Bombyx mori. Insect Molecular Biology 21:1, pages 9-20.
Crossref
Patrick M. Ferree & Satyaki Prasad. (2012) How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways. Genetics Research International 2012, pages 1-11.
Crossref
Karsten Rippe. 2011. Genome Organization and Function in the Cell Nucleus. Genome Organization and Function in the Cell Nucleus 139 167 .
Agata M. Olszak, Dominic van Essen, António J. Pereira, Sarah Diehl, Thomas Manke, Helder Maiato, Simona Saccani & Patrick Heun. (2011) Heterochromatin boundaries are hotspots for de novo kinetochore formation. Nature Cell Biology 13:7, pages 799-808.
Crossref
Yan Jiang, Anouch Matevossian, Yin Guo & Schahram Akbarian. (2011) Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice. Neuropharmacology 60:7-8, pages 1088-1097.
Crossref
Déborah Revaud, Luis M. Martins, François D. Boussin, Laure Sabatier & Chantal Desmaze. (2011) Different DNA-PKcs functions in the repair of radiation-induced and spontaneous DSBs within interstitial telomeric sequences. Chromosoma 120:3, pages 309-319.
Crossref
Meenalakshmi Chinnam & David W. Goodrich. 2011. Cancer and Development. Cancer and Development 129 169 .
Lixin Rui, N.C. Tolga Emre, Michael J. Kruhlak, Hye-Jung Chung, Christian Steidl, Graham Slack, George W. Wright, Georg Lenz, Vu N. Ngo, Arthur L. Shaffer, Weihong Xu, Hong Zhao, Yandan Yang, Laurence Lamy, R. Eric Davis, Wenming Xiao, John Powell, David Maloney, Craig J. Thomas, Peter Möller, Andreas Rosenwald, German Ott, Hans Konrad Muller-Hermelink, Kerry Savage, Joseph M. Connors, Lisa M. Rimsza, Elias Campo, Elaine S. Jaffe, Jan Delabie, Erlend B. Smeland, Dennis D. Weisenburger, Wing C. Chan, Randy D. Gascoyne, David Levens & Louis M. Staudt. (2010) Cooperative Epigenetic Modulation by Cancer Amplicon Genes. Cancer Cell 18:6, pages 590-605.
Crossref
Federico Tessadori, Kang Zeng, Erik Manders, Martijn Riool, Dean Jackson & Roel van Driel. (2010) Stable S/MAR-based episomal vectors are regulated at the chromatin level. Chromosome Research 18:7, pages 757-775.
Crossref
Jennifer F. Garcia, Phillip A. Dumesic, Paul D. Hartley, Hana El-Samad & Hiten D. Madhani. (2010) Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions. Genes & Development 24:16, pages 1758-1771.
Crossref
Robert M. Martin & M. Cristina Cardoso. (2009) Chromatin condensation modulates access and binding of nuclear proteins. The FASEB Journal 24:4, pages 1066-1072.
Crossref
Michelle S. Longworth & Nicholas J. Dyson. (2009) pRb, a local chromatin organizer with global possibilities. Chromosoma 119:1, pages 1-11.
Crossref
Federico Tessadori. (2010) L’hétérochromatine, un composant plastique du noyau des cellules d’ Arabidopsis thaliana . Biologie Aujourd'hui 204:3, pages 189-197.
Crossref
Danielle VermaakHarmit S. Malik. (2009) Multiple Roles for Heterochromatin Protein 1 Genes in Drosophila . Annual Review of Genetics 43:1, pages 467-492.
Crossref
Katharina P. Müller, Fabian Erdel, Maïwen Caudron-Herger, Caroline Marth, Barna D. Fodor, Mario Richter, Manuela Scaranaro, Joël Beaudouin, Malte Wachsmuth & Karsten Rippe. (2009) Multiscale Analysis of Dynamics and Interactions of Heterochromatin Protein 1 by Fluorescence Fluctuation Microscopy. Biophysical Journal 97:11, pages 2876-2885.
Crossref
Artem Pliss, Kishore Malyavantham, Sambit Bhattacharya, Michael Zeitz & Ronald Berezney. (2009) Chromatin dynamics is correlated with replication timing. Chromosoma 118:4, pages 459-470.
Crossref
Miroslaw Zarebski, Elzbieta Wiernasz & Jurek W. Dobrucki. (2009) Recruitment of heterochromatin protein 1 to DNA repair sites. Cytometry Part A 75A:7, pages 619-625.
Crossref
Leanne De Koning, Alexia Savignoni, Charlène Boumendil, Haniya Rehman, Bernard Asselain, Xavier Sastre‐Garau & Geneviève Almouzni. (2009) Heterochromatin protein 1α: a hallmark of cell proliferation relevant to clinical oncology. EMBO Molecular Medicine 1:3, pages 178-191.
Crossref
Bayly S. Wheeler, Jared A. Blau, Huntington F. Willard & Kristin C. Scott. (2009) The Impact of Local Genome Sequence on Defining Heterochromatin Domains. PLoS Genetics 5:4, pages e1000453.
Crossref
Nicholas L. AdkinsSteve J. McBryantCotteka N. JohnsonJennifer M. LeidyChristopher L. WoodcockCharles H. RobertJeffrey C. HansenPhilippe T. Georgel. (2008) Role of Nucleic Acid Binding in Sir3p-Dependent Interactions with Chromatin Fibers. Biochemistry 48:2, pages 276-288.
Crossref
Evgenya Y. Popova, Sharon Wald Krauss, Sarah A. Short, Gloria Lee, Jonathan Villalobos, Joan Etzell, Mark J. Koury, Paul A. Ney, Joel Anne Chasis & Sergei A. Grigoryev. (2009) Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. Chromosome Research 17:1, pages 47-64.
Crossref
Rachel Van Duyne, Rebecca Easley, Weilin Wu, Reem Berro, Caitlin Pedati, Zachary Klase, Kylene Kehn-Hall, Elizabeth K Flynn, David E Symer & Fatah Kashanchi. (2008) Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. Retrovirology 5:1.
Crossref
Joan Font-Burgada, David Rossell, Herbert Auer & Fernando Azorín. (2008) Drosophila HP1c isoform interacts with the zinc-finger proteins WOC and Relative-of-WOC to regulate gene expression . Genes & Development 22:21, pages 3007-3023.
Crossref
Thomas A. Johnson, Cem Elbi, Bhavin S. Parekh, Gordon L. Hager & Sam John. (2008) Chromatin Remodeling Complexes Interact Dynamically with a Glucocorticoid Receptor–regulated Promoter. Molecular Biology of the Cell 19:8, pages 3308-3322.
Crossref
Alexey V. Pindyurin, Lidiya V. Boldyreva, Victor V. Shloma, Tatiana D. Kolesnikova, Galina V. Pokholkova, Evgeniya N. Andreyeva, Elena N. Kozhevnikova, Igor G. Ivanoschuk, Ekaterina A. Zarutskaya, Sergey A. Demakov, Andrey A. Gorchakov, Elena S. Belyaeva & Igor F. Zhimulev. (2008) Interaction between the Drosophila heterochromatin proteins SUUR and HP1 . Journal of Cell Science 121:10, pages 1693-1703.
Crossref
Zhi-Ying Chen, Efren Riu, Chen-Yi He, Hui Xu & Mark A Kay. (2008) Silencing of Episomal Transgene Expression in Liver by Plasmid Bacterial Backbone DNA Is Independent of CpG Methylation. Molecular Therapy 16:3, pages 548-556.
Crossref
Maciej Meglicki, Maciej Zientarski & Ewa Borsuk. (2008) Constitutive heterochromatin during mouse oogenesis: The pattern of histone H3 modifications and localization of HP1α and HP1β proteins. Molecular Reproduction and Development 75:2, pages 414-428.
Crossref
Giovanna Lattanzi, Marta Columbaro, Elisabetta Mattioli, Vittoria Cenni, Daria Camozzi, Manfred Wehnert, Spartaco Santi, Massimo Riccio, Rosalba Del Coco, Nadir M. Maraldi, Stefano Squarzoni, Roland Foisner & Cristina Capanni. (2007) Pre-Lamin A processing is linked to heterochromatin organization. Journal of Cellular Biochemistry 102:5, pages 1149-1159.
Crossref
Jihui Qiu, Ying Huang, Guoqiang Chen, Zhu Chen, David J. Tweardy & Shuo Dong. (2007) Aberrant Chromatin Remodeling by Retinoic Acid Receptor α Fusion Proteins Assessed at the Single-Cell Level. Molecular Biology of the Cell 18:10, pages 3941-3951.
Crossref
Sandra Goetze, Julio Mateos-Langerak & Roel van Driel. (2007) Three-dimensional genome organization in interphase and its relation to genome function. Seminars in Cell & Developmental Biology 18:5, pages 707-714.
Crossref
Florence Cammas, Agnes Janoshazi, Thierry Lerouge & Régine Losson. (2007) Dynamic and selective interactions of the transcriptional corepressor TIF1β with the heterochromatin protein HP1 isotypes during cell differentiation. Differentiation 75:7, pages 627-637.
Crossref
Mohamed El Gazzar, Barbara K. Yoza, Jean Y.-Q. Hu, Sue L. Cousart & Charles E. McCall. (2007) Epigenetic Silencing of Tumor Necrosis Factor α during Endotoxin Tolerance. Journal of Biological Chemistry 282:37, pages 26857-26864.
Crossref
Carole Seum, Emanuela Reo, Hongzhuang Peng, Frank J Rauscher, Pierre Spierer & Séverine Bontron. (2007) Drosophila SETDB1 Is Required for Chromosome 4 Silencing. PLoS Genetics 3:5, pages e76.
Crossref
Julio Mateos-Langerak, Maartje C. Brink, Martijn S. Luijsterburg, Ineke van der Kraan, Roel van Driel & Pernette J. Verschure. (2007) Pericentromeric Heterochromatin Domains Are Maintained without Accumulation of HP1. Molecular Biology of the Cell 18:4, pages 1464-1471.
Crossref
Eva Bártová, Jiří Pacherník, Alois Kozubík & Stanislav Kozubek. (2007) Differentiation-specific association of HP1α and HP1β with chromocentres is correlated with clustering of TIF1β at these sites. Histochemistry and Cell Biology 127:4, pages 375-388.
Crossref
Kohji Hizume, Shige H. Yoshimura, Masahiro Kumeta & Kunio Takeyasu. 2007. Chromatin and Disease. Chromatin and Disease 3 28 .
Fabrizio G. Mastronardi, D. Denise Wood, Jiang Mei, Reinout Raijmakers, Vivian Tseveleki, Hans-Michael Dosch, Lesley Probert, Patrizia Casaccia-Bonnefil & Mario A. Moscarello. (2006) Increased Citrullination of Histone H3 in Multiple Sclerosis Brain and Animal Models of Demyelination: A Role for Tumor Necrosis Factor-Induced Peptidylarginine Deiminase 4 Translocation. The Journal of Neuroscience 26:44, pages 11387-11396.
Crossref
Wim De Leeuw, Pernette Verschure & Robert Van Liere. (2006) Visualization and Analysis of Large Data Collections: a Case Study Applied to Confocal Microscopy Data. IEEE Transactions on Visualization and Computer Graphics 12:5, pages 1251-1258.
Crossref
Pernette J. Verschure. (2006) Chromosome organization and gene control: It is difficult to see the picture when you are inside the frame. Journal of Cellular Biochemistry 99:1, pages 23-34.
Crossref
Hongwei Li, Tibor Rauch, Zhao-Xia Chen, Piroska E. Szabó, Arthur D. Riggs & Gerd P. Pfeifer. (2006) The Histone Methyltransferase SETDB1 and the DNA Methyltransferase DNMT3A Interact Directly and Localize to Promoters Silenced in Cancer Cells. Journal of Biological Chemistry 281:28, pages 19489-19500.
Crossref
Laura E. Norwood, Timothy J. Moss, Naira V. Margaryan, Sara L. Cook, Lindsay Wright, Elisabeth A. Seftor, Mary J.C. Hendrix, Dawn A. Kirschmann & Lori L. Wallrath. (2006) A Requirement for Dimerization of HP1Hsα in Suppression of Breast Cancer Invasion. Journal of Biological Chemistry 281:27, pages 18668-18676.
Crossref
Vladan Ondřej, Stanislav Kozubek, Emílie Lukášová, Martin Falk, Pavel Matula, Petr Matula & Michal Kozubek. (2006) Directional motion of foreign plasmid DNA to nuclear HP1 foci. Chromosome Research 14:5, pages 505-514.
Crossref
Karl P Nightingale, Laura P O’Neill & Bryan M Turner. (2006) Histone modifications: signalling receptors and potential elements of a heritable epigenetic code. Current Opinion in Genetics & Development 16:2, pages 125-136.
Crossref
Florence Hediger & Susan M Gasser. (2006) Heterochromatin protein 1: don’t judge the book by its cover!. Current Opinion in Genetics & Development 16:2, pages 143-150.
Crossref
Sophie E Polo & Geneviève Almouzni. (2006) Chromatin assembly: a basic recipe with various flavours. Current Opinion in Genetics & Development 16:2, pages 104-111.
Crossref
Sergei A. Grigoryev, Yaroslava A. Bulynko & Evgenya Y. Popova. (2006) The end adjusts the means: Heterochromatin remodelling during terminal cell differentiation. Chromosome Research 14:1, pages 53-69.
Crossref
Yuichi Kodama, Shingo Nagaya, Nozomu Sakurai, Daisuke Shibata, Atsuhiko Shinmyo & Ko Kato. (2006) Analysis of chromatin condensation states by DNase I sensitivity assay at 500-base resolution in Arabidopsis. Plant Biotechnology 23:5, pages 451-457.
Crossref
Nadir M. Maraldi, Giovanna Lattanzi, Cristina Capanni, Marta Columbaro, Elisabetta Mattioli, Patrizia Sabatelli, Stefano Squarzoni & Francesco A. Manzoli. (2006) Laminopathies: A chromatin affair. Advances in Enzyme Regulation 46:1, pages 33-49.
Crossref
Pernette J. Verschure, Astrid E. Visser & Marianne G. Rots. 2006. 163 204 .
Maartje C. Brink, Yme Velden, Wim Leeuw, Julio Mateos-Langerak, Andrew S. Belmont, Roel Driel & Pernette J. Verschure. (2005) Truncated HP1 lacking a functional chromodomain induces heterochromatinization upon in vivo targeting. Histochemistry and Cell Biology 125:1-2, pages 53-61.
Crossref
Julie A. Wallace & Terry L. Orr-Weaver. (2005) Replication of heterochromatin: insights into mechanisms of epigenetic inheritance. Chromosoma 114:6, pages 389-402.
Crossref
Niki Kourmouli, Yuh-man Sun, Sjaak van der Sar, Prim B. Singh & Jeremy P. Brown. (2005) Epigenetic regulation of mammalian pericentric heterochromatin in vivo by HP1. Biochemical and Biophysical Research Communications 337:3, pages 901-907.
Crossref
Eva Wegel & Peter Shaw. (2005) Gene activation and deactivation related changes in the three-dimensional structure of chromatin. Chromosoma 114:5, pages 331-337.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.