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Signal Transduction

CCT Chaperonin Complex Is Required for the Biogenesis of Functional Plk1

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Pages 4993-5010 | Received 03 Jan 2005, Accepted 15 Mar 2005, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Guofen Zeng, Jialiang Wang, Yanlin Huang, Yifan Lian, Dongmei Chen, Huan Wei, Chaoshuang Lin & Yuehua Huang. (2019) Overexpressing CCT6A Contributes To Cancer Cell Growth By Affecting The G1-To-S Phase Transition And Predicts A Negative Prognosis In Hepatocellular Carcinoma. OncoTargets and Therapy 12, pages 10427-10439.
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Shinji Oikawa, Hatasu Kobayashi, Yuki Kitamura, Hong Zhu, Kumi Obata, Yoshio Minabe, Maryia Dazortsava, Kyoko Ohashi, Saeko Tada-Oikawa, Hitoshi Takahashi, Kenichiro Yata, Mariko Murata & Tetsumori Yamashima. (2014) Proteomic analysis of carbonylated proteins in the monkey substantia nigra after ischemia-reperfusion. Free Radical Research 48:6, pages 694-705.
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Xiaoqi Liu, Ming Lei & Raymond L. Erikson. (2006) Normal Cells, but Not Cancer Cells, Survive Severe Plk1 Depletion. Molecular and Cellular Biology 26:6, pages 2093-2108.
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Articles from other publishers (52)

Mohita Mahajan, Angshuman Sarkar & Sukanta Mondal. (2022) Cell cycle protein BORA is associated with colorectal cancer progression by AURORA-PLK1 cascades: a bioinformatics analysis. Journal of Cell Communication and Signaling 17:3, pages 773-791.
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Kun Wang, Jian He, Changling Tu, Hui Xu, Xugang Zhang, Yongchang Lv & Chao Song. (2022) Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma. BMC Molecular and Cell Biology 23:1.
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Heba Ghozlan, Amanda Cox, Daniel Nierenberg, Stephen King & Annette R. Khaled. (2022) The TRiCky Business of Protein Folding in Health and Disease. Frontiers in Cell and Developmental Biology 10.
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Abby M Green, Rachel A DeWeerd, David R O’Leary, Ava R Hansen, Katharina E Hayer, Katarzyna Kulej, Ariel S Dineen, Julia H Szeto, Benjamin A Garcia & Matthew D Weitzman. (2021) Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity. EMBO reports 22:9.
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Yukiyo Kasahara, Satoko Osuka, Nobuyoshi Takasaki, Bayasula, Yoshihiro Koya, Natsuki Nakanishi, Tomohiko Murase, Tomoko Nakamura, Maki Goto, Akira Iwase & Hiroaki Kajiyama. (2021) Primate-specific POTE-actin gene could play a role in human folliculogenesis by controlling the proliferation of granulosa cells. Cell Death Discovery 7:1.
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Heba Ghozlan, Adrian Showalter, Eunkyung Lee, Xiang Zhu & Annette R. Khaled. (2021) Chaperonin-Containing TCP1 Complex (CCT) Promotes Breast Cancer Growth Through Correlations With Key Cell Cycle Regulators. Frontiers in Oncology 11.
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Noa Beatriz Martín-Cófreces, José María Valpuesta & Francisco Sánchez-Madrid. (2021) Folding for the Immune Synapse: CCT Chaperonin and the Cytoskeleton. Frontiers in Cell and Developmental Biology 9.
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M.M. Rivera del Alamo, T. Katila, M. Palviainen & T. Reilas. (2021) Effects of intrauterine devices on proteins in the uterine lavage fluid of mares. Theriogenology 165, pages 1-9.
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Ebru Temiz, İsmail Koyuncu & Emel Sahin. (2021) CCT3 suppression prompts apoptotic machinery through oxidative stress and energy deprivation in breast and prostate cancers. Free Radical Biology and Medicine 165, pages 88-99.
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Shailendra Yadav, Vahab Ali, Yatendra Singh, Sanjeev Kanojia & Neena Goyal. (2020) Leishmania donovani chaperonin TCP1γ subunit protects miltefosine induced oxidative damage. International Journal of Biological Macromolecules 165, pages 2607-2620.
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Shailendra Yadav, Jitendra Kuldeep, Mohammad I. Siddiqi & Neena Goyal. (2020) TCP1γ Subunit Is Indispensable for Growth and Infectivity of Leishmania donovani. Antimicrobial Agents and Chemotherapy 64:8.
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Anne E. Showalter, Ana C. Martini, Daniel Nierenberg, Kristen Hosang, Naima Ahmed Fahmi, Priya Gopalan, Amr S. Khaled, Wei Zhang & Annette R. Khaled. (2020) Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis. Scientific Reports 10:1.
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Dan Yang Wang, Kamila Kamuda, Guillermo Montoya & Pablo Mesa. 2020. HSF1 and Molecular Chaperones in Biology and Cancer. HSF1 and Molecular Chaperones in Biology and Cancer 21 40 .
Ah-Ram Kim & Kwang-Wook Choi. (2019) TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila. Oncogene 38:24, pages 4739-4754.
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Josefine Vallin & Julie Grantham. (2018) The role of the molecular chaperone CCT in protein folding and mediation of cytoskeleton-associated processes: implications for cancer cell biology. Cell Stress and Chaperones 24:1, pages 17-27.
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Li-Juan Li, Lian-Sheng Zhang, Zhi-Jian Han, Zhi-Yun He, Hao Chen & Yu-Min Li. (2017) Chaperonin containing TCP-1 subunit 3 is critical for gastric cancer growth. Oncotarget 8:67, pages 111470-111481.
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Sharon Kaisari, Danielle Sitry-Shevah, Shirly Miniowitz-Shemtov, Adar Teichner & Avram Hershko. (2017) Role of CCT chaperonin in the disassembly of mitotic checkpoint complexes. Proceedings of the National Academy of Sciences 114:5, pages 956-961.
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Anastassiia Vertii, Heidi Hehnly & Stephen Doxsey. (2016) The Centrosome, a Multitalented Renaissance Organelle. Cold Spring Harbor Perspectives in Biology 8:12, pages a025049.
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Yuanyuan Zhang, Yuqi Wang, Youheng Wei, Jiaxue Wu, Pingzhao Zhang, Suqin Shen, Hexige Saiyin, Reziya Wumaier, Xianmei Yang, Chenji Wang & Long Yu. (2016) Molecular chaperone CCT3 supports proper mitotic progression and cell proliferation in hepatocellular carcinoma cells. Cancer Letters 372:1, pages 101-109.
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Stephen T. Guest, Zachary R. Kratche, Aliccia Bollig-Fischer, Ramsi Haddad & Stephen P. Ethier. (2015) Two members of the TRiC chaperonin complex, CCT2 and TCP1 are essential for survival of breast cancer cells and are linked to driving oncogenes. Experimental Cell Research 332:2, pages 223-235.
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Xiao Cui. (2015) Overexpression of chaperonin containing TCP1, subunit 3 predicts poor prognosis in hepatocellular carcinoma. World Journal of Gastroenterology 21:28, pages 8588.
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Mehmet Koyuturk & Rod K. Nibbe. 2015. Intestinal Tumorigenesis. Intestinal Tumorigenesis 365 389 .
Moses Kasembeli, Wilson Chun Yu Lau, Soung-Hun Roh, T. Kris Eckols, Judith Frydman, Wah Chiu & David J. Tweardy. (2014) Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin. PLoS Biology 12:4, pages e1001844.
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Anne RoobolJo RoobolMartin J. CardenMatthew E. SmithJohn W. B. HersheyAmandine BastideJohn R. P. KnightAnne E. WillisC. Mark Smales. (2014) The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h. Biochemical Journal 458:2, pages 213-224.
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Antonio Garcia Trinidad, Patricia A.J. Muller, Jorge Cuellar, Marta Klejnot, Max Nobis, José María Valpuesta & Karen H. Vousden. (2013) Interaction of p53 with the CCT Complex Promotes Protein Folding and Wild-Type p53 Activity. Molecular Cell 50:6, pages 805-817.
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Chafika Boudiaf-Benmammar, Thierry Cresteil & Ronald Melki. (2013) The Cytosolic Chaperonin CCT/TRiC and Cancer Cell Proliferation. PLoS ONE 8:4, pages e60895.
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P. Schlieben, A. Meyer, C. Weise, A. Bondzio, R. Einspanier, A.D. Gruber & R. Klopfleisch. (2012) Differences in the proteome of high-grade versus low-grade canine cutaneous mast cell tumours. The Veterinary Journal 194:2, pages 210-214.
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Duthika M. Mallawaaratchy, Swetlana Mactier, Kimberley L. Kaufman, Katherine Blomfield & Richard I. Christopherson. (2012) The phosphoinositide 3-kinase inhibitor LY294002, decreases aminoacyl-tRNA synthetases, chaperones and glycolytic enzymes in human HT-29 colorectal cancer cells. Journal of Proteomics 75:5, pages 1590-1599.
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Nandini V. L. Hayes, Lyne Jossé, C. Mark Smales & Martin J. Carden. (2011) Modulation of Phosducin-Like Protein 3 (PhLP3) Levels Promotes Cytoskeletal Remodelling in a MAPK and RhoA-Dependent Manner. PLoS ONE 6:12, pages e28271.
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Inés G Muñoz, Hugo Yébenes, Min Zhou, Pablo Mesa, Marina Serna, Ah Young Park, Elisabeth Bragado-Nilsson, Ana Beloso, Guillermo de Cárcer, Marcos Malumbres, Carol V Robinson, José M Valpuesta & Guillermo Montoya. (2010) Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin. Nature Structural & Molecular Biology 18:1, pages 14-19.
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X. Shawn Liu, Bing Song & Xiaoqi Liu. (2010) The substrates of Plk1, beyond the functions in mitosis. Protein & Cell 1:11, pages 999-1010.
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Hui Zhu, Yugui Cui, Jin Xie, Ling Chen, Xiangxiang Chen, Xuejiang Guo, Yefei Zhu, Xinghai Wang, Jiansun Tong, Zuomin Zhou, Yue Jia, Yan-he Lue, Amiya Sinha Hikim, Christina Wang, Ronald S. Swerdloff & Jiahao Sha. (2010) Proteomic analysis of testis biopsies in men treated with transient scrotal hyperthermia reveals the potential targets for contraceptive development. PROTEOMICS 10:19, pages 3480-3493.
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Zhu Qian-Lin, Wang Ting-Feng, Cao Qi-Feng, Zheng Min-Hua & Lu Ai-Guo. (2010) Inhibition of cytosolic chaperonin CCTζ-1 expression depletes proliferation of colorectal carcinoma in vitro. Journal of Surgical Oncology 102:5, pages 419-423.
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Hongchang Li, X. Shawn Liu, Xiaoming Yang, Bing Song, Yun Wang & Xiaoqi Liu. (2010) Polo-like kinase 1 phosphorylation of p150 Glued facilitates nuclear envelope breakdown during prophase . Proceedings of the National Academy of Sciences 107:33, pages 14633-14638.
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Rod K. Nibbe, Mehmet Koyutürk & Mark R. Chance. (2010) An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer. PLoS Computational Biology 6:1, pages e1000639.
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Yuki Abe, Sang-Oh Yoon, Kazuishi Kubota, Michelle C. Mendoza, Steven P. Gygi & John Blenis. (2009) p90 Ribosomal S6 Kinase and p70 Ribosomal S6 Kinase Link Phosphorylation of the Eukaryotic Chaperonin Containing TCP-1 to Growth Factor, Insulin, and Nutrient Signaling. Journal of Biological Chemistry 284:22, pages 14939-14948.
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Julia R. Zebol, Niamh M. Hewitt, Paul A.B. Moretti, Helen E. Lynn, Julie A. Lake, Peng Li, Mathew A. Vadas, Binks W. Wattenberg & Stuart M. Pitson. (2009) The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1. The International Journal of Biochemistry & Cell Biology 41:4, pages 822-827.
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Drew M Lowery, Karl R Clauser, Majbrit Hjerrild, Dan Lim, Jes Alexander, Kazuhiro Kishi, Shao-En Ong, Steen Gammeltoft, Steven A Carr & Michael B Yaffe. (2007) Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate. The EMBO Journal 26:9, pages 2262-2273.
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