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Signal Transduction

Conditional Transgenic System for Mouse Aurora A Kinase: Degradation by the Ubiquitin Proteasome Pathway Controls the Level of the Transgenic Protein

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Pages 5270-5281 | Received 30 Dec 2004, Accepted 16 Mar 2005, Published online: 27 Mar 2023

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Saili Moghe, Fei Jiang, Yoshie Miura, Ronald L. Cerny, Ming-Ying Tsai & Manabu Furukawa. (2012) The CUL3-KLHL18 ligase regulates mitotic entry and ubiquitylates Aurora-A. Biology Open 1:2, pages 82-91.
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Florian Jantscher, Christine Pirker, Christoph-Erik Mayer, Walter Berger & Hedwig Sutterluety. (2011) Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities. Molecular Cancer 10:1.
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Aurélie Thollet, Julie A Vendrell, Léa Payen, Sandra E Ghayad, Sabrina Ben Larbi, Evelyne Grisard, Colin Collins, Marie Villedieu & Pascale A Cohen. (2010) ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells. Molecular Cancer 9:1.
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Olga V. Plotnikova, Elena N. Pugacheva, Roland L. Dunbrack & Erica A. Golemis. (2010) Rapid calcium-dependent activation of Aurora-A kinase. Nature Communications 1:1.
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Enrique C. Torchia, Yiyun Chen, Hong Sheng, Hiroshi Katayama, James Fitzpatrick, William R. Brinkley, Carlos Caulin, Subrata Sen & Dennis R. Roop. (2009) A Genetic Variant of Aurora Kinase A Promotes Genomic Instability Leading to Highly Malignant Skin Tumors. Cancer Research 69:18, pages 7207-7215.
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Zhijun Chen, Hanna Leskinen, Erkki Liimatta, Raija T. Sormunen, Ilkka J. Miinalainen, Ilmo E. Hassinen & J. Kalervo Hiltunen. (2009) Myocardial Overexpression of Mecr, a Gene of Mitochondrial FAS II Leads to Cardiac Dysfunction in Mouse. PLoS ONE 4:5, pages e5589.
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Chao-Chin Li, Hui-Yi Chu, Chu-Wen Yang, Chen-Kung Chou & Ting-Fen Tsai. (2009) Aurora-A Overexpression in Mouse Liver Causes p53-Dependent Premitotic Arrest during Liver Regeneration. Molecular Cancer Research 7:5, pages 678-688.
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D Zhang, T Shimizu, N Araki, T Hirota, M Yoshie, K Ogawa, N Nakagata, M Takeya & H Saya. (2008) Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice. Oncogene 27:31, pages 4305-4314.
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Tomokazu Fukuda, Yasuyuki Kondo & Hitoshi Nakagama. (2008) The Anti-Proliferative Effects of the CHFR Depend on the Forkhead Associated Domain, but not E3 Ligase Activity Mediated by Ring Finger Domain. PLoS ONE 3:3, pages e1776.
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Shojiro Kitajima, Yasusei Kudo, Ikuko Ogawa, Masaaki Tatsuka, Hidehiko Kawai, Michele Pagano & Takashi Takata. (2007) Constitutive Phosphorylation of Aurora-A on Ser51 Induces Its Stabilization and Consequent Overexpression in Cancer. PLoS ONE 2:9, pages e944.
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Daniel Gray, Adrian M. Jubb, Deborah Hogue, Patrick Dowd, Noelyn Kljavin, Sothy Yi, Wei Bai, Gretchen Frantz, Zemin Zhang, Hartmut Koeppen, Frederic J. de Sauvage & David P. Davis. (2005) Maternal Embryonic Leucine Zipper Kinase/Murine Protein Serine-Threonine Kinase 38 Is a Promising Therapeutic Target for Multiple Cancers. Cancer Research 65:21, pages 9751-9761.
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