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Signal Transduction

Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma

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Pages 5675-5686 | Received 29 Nov 2004, Accepted 27 Mar 2005, Published online: 27 Mar 2023

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Scott M. Welford, Mary Jo Dorie, Xiaofeng Li, Volker H. Haase & Amato J. Giaccia. (2010) Renal Oxygenation Suppresses VHL Loss-Induced Senescence That Is Caused by Increased Sensitivity to Oxidative Stress. Molecular and Cellular Biology 30:19, pages 4595-4603.
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Peter Ebbesen, Erik O. Pettersen, Thomas A. Gorr, Gerhard Jobst, Kaye Williams, Jochen Kieninger, Roland H. Wenger, Silvia Pastorekova, Ludwig Dubois, Philippe Lambin, Brad G. Wouters, Twan Van Den Beucken, Claudiu T. Supuran, Lorenz Poellinger, Peter Ratcliffe, Arvydas Kanopka, Agnes Görlach, Max Gasmann, Adrian L. Harris, Patrick Maxwell & Andrea Scozzafava. (2009) Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies. Journal of Enzyme Inhibition and Medicinal Chemistry 24:sup1, pages 1-39.
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Johanna Sandlund, Börje Ljungberg, Pernilla Wikström, Kjell Grankvist, Gudrun Lindh & Torgny Rasmuson. (2009) Hypoxia-inducible factor-2α mRNA expression in human renal cell carcinoma. Acta Oncologica 48:6, pages 909-914.
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W Kimryn Rathmell & Shufen Chen. (2008) VHL inactivation in renal cell carcinoma: implications for diagnosis, prognosis and treatment. Expert Review of Anticancer Therapy 8:1, pages 63-73.
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Lianjie Li, Liang Zhang, Xiaoping Zhang, Qin Yan, Yoji Andrew Minamishima, Aria F. Olumi, Mao Mao, Steven Bartz & William G. Kaelin$suffix/text()$suffix/text(). (2007) Hypoxia-Inducible Factor Linked to Differential Kidney Cancer Risk Seen with Type 2A and Type 2B VHL Mutations. Molecular and Cellular Biology 27:15, pages 5381-5392.
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Qin Yan, Steven Bartz, Mao Mao, Lianjie Li & William G. Kaelin$suffix/text()$suffix/text(). (2007) The Hypoxia-Inducible Factor 2α N-Terminal and C-Terminal Transactivation Domains Cooperate To Promote Renal Tumorigenesis In Vivo. Molecular and Cellular Biology 27:6, pages 2092-2102.
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Cheng-Jun Hu, Sangeeta Iyer, Aneesa Sataur, Kelly L. Covello, Lewis A. Chodosh & M. Celeste Simon. (2006) Differential Regulation of the Transcriptional Activities of Hypoxia-Inducible Factor 1 Alpha (HIF-1α) and HIF-2α in Stem Cells. Molecular and Cellular Biology 26:9, pages 3514-3526.
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Gregg L Semenza. (2006) Development of novel therapeutic strategies that target HIF-1. Expert Opinion on Therapeutic Targets 10:2, pages 267-280.
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Thambi Dorai, Ihor Sawczuk, Jaromir Pastorek, Peter H. Wiernik & Janice P. Dutcher. (2006) Role of Carbonic Anhydrases in the Progression of Renal Cell Carcinoma Subtypes: Proposal of a Unified Hypothesis. Cancer Investigation 24:8, pages 754-779.
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