19
Views
53
CrossRef citations to date
0
Altmetric
Gene Expression

Gamma Interferon-Inducible Protein 10 Induces HeLa Cell Apoptosis through a p53-Dependent Pathway Initiated by Suppression of Human Papillomavirus Type 18 E6 and E7 Expression

, , , , , & show all
Pages 6247-6258 | Received 13 Oct 2004, Accepted 21 Apr 2005, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Hongxing Chu, Bo Jia, Xiaoling Qiu, Jie Pan, Xiang Sun, Zhiping Wang & Jianjiang Zhao. (2017) Investigation of proliferation and migration of tongue squamous cell carcinoma promoted by three chemokines, MIP-3α, MIP-1β, and IP-10. OncoTargets and Therapy 10, pages 4193-4203.
Read now
Jing Gao, Jin Gao, Lan Qian, Xia Wang, Mingyuan Wu, Yang Zhang, Hao Ye, Shunying Zhu, Yan Yu & Wei Han. (2014) Activation of p38-MAPK by CXCL4/CXCR3 axis contributes to p53-dependent intestinal apoptosis initiated by 5-fluorouracil. Cancer Biology & Therapy 15:8, pages 982-991.
Read now
Barbara Kroczynska, Surinder Kaur, Efstratios Katsoulidis, Beata Majchrzak-Kita, Antonella Sassano, Sara C. Kozma, Eleanor N. Fish & Leonidas C. Platanias. (2009) Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)- and Ribosomal Protein S6K-Mediated Signals. Molecular and Cellular Biology 29:10, pages 2865-2875.
Read now

Articles from other publishers (50)

Maryam Ahmadzadeh & Elham Mohit. (2023) Therapeutic potential of a novel IP-10-(anti-HER2 scFv) fusion protein for the treatment of HER2-positive breast cancer. Biotechnology Letters 45:3, pages 371-385.
Crossref
Mohd Israr, James A. DeVoti, Christopher J. Papayannakos & Vincent R. Bonagura. (2022) Role of chemokines in HPV-induced cancers. Seminars in Cancer Biology 87, pages 170-183.
Crossref
Jiahua Xing, Yan Li, Youbai Chen & Yan Han. (2022) A novel inflammatory response-related signature predicts the prognosis of cutaneous melanoma and the effect of antitumor drugs. World Journal of Surgical Oncology 20:1.
Crossref
Yun-Cian Huang, Jau-Ling Huang, Lu-Chia Tseng, Ping-Hung Yu, Si-Yun Chen & Chang-Shen Lin. (2022) High Expression of Interferon Pathway Genes CXCL10 and STAT2 Is Associated with Activated T-Cell Signature and Better Outcome of Oral Cancer Patients. Journal of Personalized Medicine 12:2, pages 140.
Crossref
Hayk Mnatsakanyan, Manuel Salmeron‐Sanchez & Patricia Rico. (2021) Lithium Directs Embryonic Stem Cell Differentiation Into Hemangioblast‐Like Cells. Advanced Biology 5:8, pages 2000569.
Crossref
Maryam Ahmadzadeh, Farzaneh Farshdari, Mahdi Behdani, Leila Nematollahi & Elham Mohit. (2020) Cloning, Expression and One-Step Purification of a Novel IP-10-(anti-HER2 scFv) Fusion Protein in Escherichia coli. International Journal of Peptide Research and Therapeutics 27:1, pages 433-446.
Crossref
Weiwei Song, Hongli Yin, Chenguang Han, Qiantai Mao, Jing Tang, Zhaoshuai Ji, Xu Yan, Lan Wang, Shengnan Liu & Chao Ai. (2021) The role of CXCL10 in prognosis of patients with colon cancer and tumor microenvironment remodeling. Medicine 100:38, pages e27224.
Crossref
Toktam Kazemi FardSamareh TavakoliReza AhmadiNariman MoradiReza FadaeiAsghar MohammadiSoudabeh Fallah. (2020) Evaluation of IP10 and miRNA 296-a Expression Levels in Peripheral Blood Mononuclear Cell of Coronary Artery Disease Patients and Controls. DNA and Cell Biology 39:9, pages 1678-1684.
Crossref
Jie Gao, Lingling Wu, Siyang Wang & Xiangmei Chen. (2020) Role of Chemokine (C–X–C Motif) Ligand 10 (CXCL10) in Renal Diseases. Mediators of Inflammation 2020, pages 1-16.
Crossref
Guang Li, Xian Li, Meng Yang, Lvzi Xu, Shixiong Deng & Longke Ran. (2017) Prediction of biomarkers of oral squamous cell carcinoma using microarray technology. Scientific Reports 7:1.
Crossref
Ying ZhouFei XuFeng TaoDingqing FengBin LingLili QianXia YangQingyuan WangHuiyan WangWeidong ZhaoYong ChengGe ShanDhan V. KalvakolanuWeihua Xiao. (2016) GRIM-19 Restores Cervical Cancer Cell Senescence by Repressing hTERT Transcription . Journal of Interferon & Cytokine Research 36:8, pages 506-515.
Crossref
Raffaele AltaraMarco Manca, Rita D. Brandão, Asad Zeidan, George W. BoozFouad A. Zouein. (2016) Emerging importance of chemokine receptor CXCR3 and its ligands in cardiovascular diseases. Clinical Science 130:7, pages 463-478.
Crossref
Jing Huang, Ningying Xu & Jianzhi Pan. (2016) A SNP in the porcine chemokine (C-X-C motif) ligand 10 gene is associated with blood hemoglobin concentration . Animal Genetics 47:1, pages 134-135.
Crossref
Charles T. Spencer, Jelena S. Bezbradica, Mireya G. Ramos, Chenoa D. Arico, Stephanie B. Conant, Pavlo Gilchuk, Jennifer J. Gray, Mu Zheng, Xinnan Niu, William Hildebrand, Andrew J. Link & Sebastian Joyce. (2015) Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules. PROTEOMICS - Clinical Applications 9:11-12, pages 1035-1052.
Crossref
Yutaka Aoyama, Koichi Kobayashi, Yoshihiro Morishita, Kengo Maeda & Toyoaki Murohara. (2015) Wnt11 gene therapy with adeno-associated virus 9 improves the survival of mice with myocarditis induced by coxsackievirus B3 through the suppression of the inflammatory reaction. Journal of Molecular and Cellular Cardiology 84, pages 45-51.
Crossref
Zhiwei Hu, Samira A. Brooks, Valérian Dormoy, Chia-Wen Hsu, Hsue-Yin Hsu, Liang-Tzung Lin, Thierry Massfelder, W.Kimryn Rathmell, Menghang Xia, Fahd Al-Mulla, Rabeah Al-Temaimi, Amedeo Amedei, Dustin G. Brown, Kalan R. Prudhomme, Anna Maria Colacci, Roslida A. Hamid, Chiara Mondello, Jayadev Raju, Elizabeth P. Ryan, Jordan Woodrick, A.Ivana Scovassi, Neetu Singh, Monica Vaccari, Rabindra Roy, Stefano Forte, Lorenzo Memeo, Hosni K. Salem, Leroy Lowe, Lasse Jensen, William H. Bisson & Nicole Kleinstreuer. (2015) Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis. Carcinogenesis 36:Suppl 1, pages S184-S202.
Crossref
Diana Saleiro, Swarna Mehrotra, Barbara Kroczynska, Elspeth M. Beauchamp, Pawel Lisowski, Beata Majchrzak-Kita, Tushar D. Bhagat, Brady L. Stein, Brandon McMahon, Jessica K. Altman, Ewa M. Kosciuczuk, Darren P. Baker, Chunfa Jie, Nadereh Jafari, Craig B. Thompson, Ross L. Levine, Eleanor N. Fish, Amit K. Verma & Leonidas C. Platanias. (2015) Central Role of ULK1 in Type I Interferon Signaling. Cell Reports 11:4, pages 605-617.
Crossref
Yu-Ying Chen, Cheng-Ying Hsieh, Thanasekaran Jayakumar, Kuan-Hung Lin, Duen-Suey Chou, Wan-Jung Lu, Ming-Jen Hsu & Joen-Rong Sheu. (2014) Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade. Scientific Reports 4:1.
Crossref
Jing Huang, Guojian Ma, Liangliang Fu, Hao Jia, Mengjin Zhu, Xinyun Li & Shuhong Zhao. (2014) Pseudorabies viral replication is inhibited by a novel target of miR-21. Virology 456-457, pages 319-328.
Crossref
Tim De Schutter, Graciela Andrei, Dimitri Topalis, Lieve Naesens & Robert Snoeck. (2013) Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage. BMC Medical Genomics 6:1.
Crossref
Eliana Guerriero, Francesca Capone, Fabiola Rusolo, Giovanni Colonna, Giuseppe Castello & Susan Costantini. (2013) Dissimilar cytokine patterns in different human liver and colon cancer cell lines. Cytokine 64:2, pages 584-589.
Crossref
Catherine E. Jauregui, Qian Wang, Christopher J. Wright, Hiroki Takeuchi, Silvia M. Uriarte & Richard J. Lamont. (2013) Suppression of T-Cell Chemokines by Porphyromonas gingivalis. Infection and Immunity 81:7, pages 2288-2295.
Crossref
Hacer Sahin, Erawan Borkham-Kamphorst, Nicole T. do O, Marie-Luise Berres, Michaela Kaldenbach, Petra Schmitz, Ralf Weiskirchen, Christian Liedtke, Konrad L. Streetz, Kathrin Maedler, Christian Trautwein & Hermann E. Wasmuth. (2013) Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes. Hepatology 57:2, pages 797-805.
Crossref
Yu-Ying Chen, Ming-Jen Hsu, Joen-Rong Sheu, Lin-Wen Lee & Cheng-Ying Hsieh. (2013) Andrographolide, a Novel NF- κ B Inhibitor, Induces Vascular Smooth Muscle Cell Apoptosis via a Ceramide-p47phox-ROS Signaling Cascade . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-10.
Crossref
Abubaker M.E. Sidahmed, Alberto J. León, Steven E. Bosinger, David Banner, Ali Danesh, Mark J. Cameron & David J. Kelvin. (2012) CXCL10 contributes to p38-mediated apoptosis in primary T lymphocytes in vitro. Cytokine 59:2, pages 433-441.
Crossref
LING-LIN YANG, BI-QIONG WANG, LAN-LAN CHEN, HUI-QUN LUO & JING-BO WU. (2012) CXCL10 enhances radiotherapy effects in HeLa cells through cell cycle redistribution. Oncology Letters 3:2, pages 383-386.
Crossref
Geoffrey M. Matthews, Andrea Newbold & Ricky W. Johnstone. 2012. Histone Deacetylase Inhibitors as Cancer Therapeutics. Histone Deacetylase Inhibitors as Cancer Therapeutics 165 197 .
Ying Zhou, Ying Wei, Jing Zhu, Qingyuan Wang, Liang Bao, Yang Ma, Yu Chen, Dingqing Feng, Aijin Zhang, Jie Sun, Shreeram C. Nallar, Keng Shen, Dhananjaya V. Kalvakolanu, Weihua Xiao & Bin Ling. (2011) GRIM-19 Disrupts E6/E6AP Complex to Rescue p53 and Induce Apoptosis in Cervical Cancers. PLoS ONE 6:7, pages e22065.
Crossref
Ya-Fen Hsu, Joen-Rong Sheu, George Hsiao, Chien-Huang Lin, Tsai-Hsing Chang, Pei-Ting Chiu, Chun-Yu Wang & Ming-Jen Hsu. (2011) p53 in trichostatin A induced C6 glioma cell death. Biochimica et Biophysica Acta (BBA) - General Subjects 1810:5, pages 504-513.
Crossref
Yan Yue, Jun Gui, Wenqing Ai, Wei Xu & Sidong Xiong. (2011) Direct Gene Transfer with IP-10 Mutant Ameliorates Mouse CVB3-Induced Myocarditis by Blunting Th1 Immune Responses. PLoS ONE 6:3, pages e18186.
Crossref
Jeroen E. J. Guikema, Carol E. Schrader, Michael H. Brodsky, Erin K. Linehan, Adam Richards, Nahla El Falaky, Daniel H. Li, Hayla K. Sluss, Eva Szomolanyi-Tsuda & Janet Stavnezer. (2010) p53 Represses Class Switch Recombination to IgG2a through Its Antioxidant Function. The Journal of Immunology 184:11, pages 6177-6187.
Crossref
Lipi Singh, Sunil Kumar Arora, Dapinder K. Bakshi, Siddarth Majumdar & Jai Dev Wig. (2009) Potential role of CXCL10 in the induction of cell injury and mitochondrial dysfunction. International Journal of Experimental Pathology 91:3, pages 210-223.
Crossref
Alhousseynou Sall, Huifang M. Zhang, Dexin Qiu, Zhongbin Liu, Ji Yuan, Zhen Liu, Travis Lim, Xin Ye, David Marchant, Bruce McManus & Decheng Yang. (2010) Pro-apoptotic activity of mBNIP-21 depends on its BNIP-2 and Cdc42GAP homology (BCH) domain and is enhanced by coxsackievirus B3 infection. Cellular Microbiology 12:5, pages 599-614.
Crossref
S. V. M. Durand, M. M. Hulst, A. A. C. de Wit, L. Mastebroek & W. L. A. Loeffen. (2009) Activation and modulation of antiviral and apoptotic genes in pigs infected with classical swine fever viruses of high, moderate or low virulence. Archives of Virology 154:9, pages 1417-1431.
Crossref
Ji YuanZhen LiuTravis LimHuifang ZhangJianqing HeElizabeth WalkerCourtney ShierYinjing WangYue SuAlhousseynou SallBruce McManusDecheng Yang. (2009) CXCL10 Inhibits Viral Replication Through Recruitment of Natural Killer Cells in Coxsackievirus B3-Induced Myocarditis. Circulation Research 104:5, pages 628-638.
Crossref
Huijuan Li, Tao Yi, Shuyun Zhao, Pin Chen, Chenxian Cheng, Yuquan Wei & Xia Zhao. (2009) The anti-condyloma acuminatum effects of interferon-inducible protein 10 in vitro . International Journal of Dermatology 48:2, pages 136-141.
Crossref
Fabienne T. Schulthess, Federico Paroni, Nadine S. Sauter, Luan Shu, Pascale Ribaux, Leena Haataja, Robert M. Strieter, Jose Oberholzer, Charles C. King & Kathrin Maedler. (2009) CXCL10 Impairs β Cell Function and Viability in Diabetes through TLR4 Signaling. Cell Metabolism 9:2, pages 125-139.
Crossref
Surinder Kaur, Antonella Sassano, Ajith M. Joseph, Beata Majchrzak-Kita, Elizabeth A. Eklund, Amit Verma, Saskia M. Brachmann, Eleanor N. Fish & Leonidas C. Platanias. (2008) Dual Regulatory Roles of Phosphatidylinositol 3-Kinase in IFN Signaling. The Journal of Immunology 181:10, pages 7316-7323.
Crossref
Andreas Oliver Weinzierl, Gudrun Szalay, Hartwig Wolburg, Martina Sauter, Hans-Georg Rammensee, Reinhard Kandolf, Stefan Stevanović & Karin Klingel. (2008) Effective Chemokine Secretion by Dendritic Cells and Expansion of Cross-Presenting CD4 − /CD8 + Dendritic Cells Define a Protective Phenotype in the Mouse Model of Coxsackievirus Myocarditis . Journal of Virology 82:16, pages 8149-8160.
Crossref
Surinder KaurAntonella SassanoBlazej DolniakSonali JoshiBeata Majchrzak-KitaDarren P. Baker, Nissim Hay, Eleanor N. FishLeonidas C. Platanias. (2008) Role of the Akt pathway in mRNA translation of interferon-stimulated genes. Proceedings of the National Academy of Sciences 105:12, pages 4808-4813.
Crossref
Xiaoning Si, David Marchant, Decheng Yang, Bruce M. McManus & Honglin Luo. 2008. Signal Transduction in the Cardiovascular System in Health and Disease. Signal Transduction in the Cardiovascular System in Health and Disease 267 284 .
Tae-Kyung Kim, Joong-Seob Lee, Se-Yeong Oh, Xun Jin, Yun-Jaie Choi, Tae-Hoon Lee, Eun ho Lee, Young-Ki Choi, Seungkwon You, Yong Gu Chung, Jang-Bo Lee, Ronald A. DePinho, Lynda Chin & Hyunggee Kim. (2007) Direct Transcriptional Activation of Promyelocytic Leukemia Protein by IFN Regulatory Factor 3 Induces the p53-Dependent Growth Inhibition of Cancer Cells. Cancer Research 67:23, pages 11133-11140.
Crossref
L Singh, D.K. Bakshi, S. Majumdar, R.K. Vasishta, S.K. Arora & J.D. Wig. (2007) Expression of Interferon-Gamma-Inducible Protein-10 and Its Receptor CXCR3 in Chronic Pancreatitis. Pancreatology 7:5-6, pages 479-490.
Crossref
Ming-Jen Hsu, Chung Y. Hsu, Bing-Chang Chen, Mei-Chieh Chen, George Ou & Chien-Huang Lin. (2007) Apoptosis Signal-Regulating Kinase 1 in Amyloid β Peptide-Induced Cerebral Endothelial Cell Apoptosis. The Journal of Neuroscience 27:21, pages 5719-5729.
Crossref
David H. W. Chau, Ji Yuan, Huifang Zhang, Paul Cheung, Travis Lim, Zhen Liu, Alhousseynou Sall & Decheng Yang. (2006) Coxsackievirus B3 proteases 2A and 3C induce apoptotic cell death through mitochondrial injury and cleavage of eIF4GI but not DAP5/p97/NAT1. Apoptosis 12:3, pages 513-524.
Crossref
Surinder Kaur, Lakhvir Lal, Antonella Sassano, Beata Majchrzak-Kita, Maya Srikanth, Darren P. Baker, Emmanuel Petroulakis, Nissim Hay, Nahum Sonenberg, Eleanor N. Fish & Leonidas C. Platanias. (2007) Regulatory Effects of Mammalian Target of Rapamycin-activated Pathways in Type I and II Interferon Signaling. Journal of Biological Chemistry 282:3, pages 1757-1768.
Crossref
Thomas T. Murooka, Mark M. Wong, Ramtin Rahbar, Beata Majchrzak-Kita, Amanda E.I. Proudfoot & Eleanor N. Fish. (2006) CCL5-CCR5-mediated Apoptosis in T Cells. Journal of Biological Chemistry 281:35, pages 25184-25194.
Crossref
Ming-Fang Hsieh, Szu-Liang Lai, Jia-Perng Chen, Jui-Ming Sung, Yi-Ling Lin, Betty A. Wu-Hsieh, Craig Gerard, Andrew Luster & Fang Liao. (2006) Both CXCR3 and CXCL10/IFN-Inducible Protein 10 Are Required for Resistance to Primary Infection by Dengue Virus. The Journal of Immunology 177:3, pages 1855-1863.
Crossref
M Vogt, K Butz, S Dymalla, J Semzow & F Hoppe-Seyler. (2006) Inhibition of Bax activity is crucial for the antiapoptotic function of the human papillomavirus E6 oncoprotein. Oncogene 25:29, pages 4009-4015.
Crossref
Yuh-Cheng Yang, Yun-Ting Hsu, Chao-Chih Wu, Hsiang-Ting Chen & Mau-Sun Chang. (2006) Silencing of astrin induces the p53-dependent apoptosis by suppression of HPV18 E6 expression and sensitizes cells to paclitaxel treatment in HeLa cells. Biochemical and Biophysical Research Communications 343:2, pages 428-434.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.