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Molecular and Cellular Biology Volume 25, 2005 - Issue 15
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Gene Expression

Akt Phosphorylation of p300 at Ser-1834 Is Essential for Its Histone Acetyltransferase and Transcriptional Activity

Wei-Chien HuangDepartment of Pharmacology, College of Medicine, National Taiwan University, Taipei10018, Taiwan
&
Ching-Chow ChenDepartment of Pharmacology, College of Medicine, National Taiwan University, Taipei10018, TaiwanCorrespondence[email protected]
Pages 6592-6602 | Received 24 Oct 2004, Accepted 04 May 2005, Published online: 27 Mar 2023

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Shashank Srivastava, Shakur Mohibi, Sameer Mirza, Hamid Band & Vimla Band. (2017) Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway. Cell Cycle 16:16, pages 1515-1525.
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Shakur Mohibi, Shashank Srivastava, Aditya Bele, Sameer Mirza, Hamid Band & Vimla Band. (2016) Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation. Molecular and Cellular Biology 36:19, pages 2487-2502.
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Omar Motiño, Daniel E. Francés, Rafael Mayoral, Luis Castro-Sánchez, María Fernández-Velasco, Lisardo Boscá, Carmelo García-Monzón, Rocío Brea, Marta Casado, Noelia Agra & Paloma Martín-Sanz. (2015) Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver Is DEAD-Box Helicase p68 (DDX5) Dependent: Role in Insulin Signaling. Molecular and Cellular Biology 35:14, pages 2554-2567.
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Masashi Okada & Keqiang Ye. (2009) Nuclear phosphoinositide signaling regulates messenger RNA export. RNA Biology 6:1, pages 12-16.
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Linh N. Tsai, Tony K. S. Ku, Nader K. Salib & David L. Crowe. (2008) Extracellular Signals Regulate Rapid Coactivator Recruitment at AP-1 Sites by Altered Phosphorylation of both CREB Binding Protein and c-jun. Molecular and Cellular Biology 28:13, pages 4240-4250.
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Asish K. Ghosh. (2021) Acetyltransferase p300 Is a Putative Epidrug Target for Amelioration of Cellular Aging-Related Cardiovascular Disease. Cells 10:11, pages 2839.
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Amanuel Tafessu & Laura A. Banaszynski. (2020) Establishment and function of chromatin modification at enhancers. Open Biology 10:10.
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Zhen Fan, Jing Wu, Qiu-nan Chen, An-kang Lyu, Jin-liang Chen, Yue Sun, Qiong Lyu, Yu-xing Zhao, Ai Guo, Zhi-yin Liao, Yun-fei Yang, Shi-yu Zhu, Xu-shun Jiang, Bo Chen & Qian Xiao. (2020) Type 2 diabetes-induced overactivation of P300 contributes to skeletal muscle atrophy by inhibiting autophagic flux. Life Sciences 258, pages 118243.
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Stine M. Præstholm, Majken S. Siersbæk, Ronni Nielsen, Xuguang Zhu, Anthony N. Hollenberg, Sheue-yann Cheng & Lars Grøntved. (2020) Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone. PLOS Genetics 16:5, pages e1008770.
Crossref
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Crossref
Md Shamim Hossain, Yutaka Oomura, Takehiko Fujino & Koichi Akashi. (2020) Glucose signaling in the brain and periphery to memory. Neuroscience & Biobehavioral Reviews 110, pages 100-113.
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Crossref
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Crossref
Zihan Liu, Yonglai He, Xiaojuan Lian, Hong Zou, Yalan Huang, Ning Wang, Jianming Hu, Xiaobin Cui, Jin Zhao, Wenjie Zhang, Wenyi Gu, Lijuan Pang & Yan Qi. (2019) Prognostic role of upregulated P300 expression in human cancers: A clinical study of synovial sarcoma and a meta‑analysis. Experimental and Therapeutic Medicine.
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Vitor F. Martins, Jessica R. Dent, Kristoffer Svensson, Shahriar Tahvilian, Maedha Begur, Shivani Lakkaraju, Elisa H. Buckner, Samuel A. LaBarge, Byron Hetrick, Carrie E. McCurdy & Simon Schenk. (2019) Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity. American Journal of Physiology-Endocrinology and Metabolism 316:6, pages E1024-E1035.
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Jonathan M. Fahey, Witold Korytowski & Albert W. Girotti. (2019) Upstream signaling events leading to elevated production of pro-survival nitric oxide in photodynamically-challenged glioblastoma cells. Free Radical Biology and Medicine 137, pages 37-45.
Crossref
Karla Rubio, Indrabahadur Singh, Stephanie Dobersch, Pouya Sarvari, Stefan Günther, Julio Cordero, Aditi Mehta, Lukasz Wujak, Hector Cabrera-Fuentes, Cho-Ming Chao, Peter Braubach, Saverio Bellusci, Werner Seeger, Andreas Günther, Klaus T. Preissner, Malgorzata Wygrecka, Rajkumar Savai, Dulce Papy-Garcia, Gergana Dobreva, Mathias Heikenwalder, Soni Savai-Pullamsetti, Thomas Braun & Guillermo Barreto. (2019) Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. Nature Communications 10:1.
Crossref
Dongki Yang & Jaehong Kim. (2019) Mitochondrial Retrograde Signalling and Metabolic Alterations in the Tumour Microenvironment. Cells 8:3, pages 275.
Crossref
Jonathan W. Boyd, Nicole Prince & Marc Birringer. 2019. Cellular Signal Transduction in Toxicology and Pharmacology. Cellular Signal Transduction in Toxicology and Pharmacology 267 289 .
Diego Molina-Serrano, Dimitris Kyriakou & Antonis Kirmizis. (2019) Histone Modifications as an Intersection Between Diet and Longevity. Frontiers in Genetics 10.
Crossref
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Crossref
Larissa Leggieri Coa, Thiago Ferreira Abreu, Alexandre Keiji Tashima, Janaina Green, Renata Castiglioni Pascon, Marcelo Afonso Vallim & Joel Machado-Jr. (2019) AKT/protein kinase B associates with β-actin in the nucleus of melanoma cells. Bioscience Reports 39:1.
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Guojian Li, Qionghui Yang, Yong Yang, Guokai Yang, Jia Wan, Zhenhuan Ma, Lingjuan Du, Yi Sun & Guimin Ζhang. (2019) Laminar shear stress alters endothelial KCa2.3 expression in H9c2 cells partially via regulating the PI3K/Akt/p300 axis. International Journal of Molecular Medicine.
Crossref
Chao-Hui Zheng, Jia-Bin Wang, Man-Qiang Lin, Peng-Yang Zhang, Li-Chao Liu, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Jian-Wei Xie, Ping Li & Chang-Ming Huang. (2018) CDK5RAP3 suppresses Wnt/β-catenin signaling by inhibiting AKT phosphorylation in gastric cancer. Journal of Experimental & Clinical Cancer Research 37:1.
Crossref
Shanshan Li, Chu Xu, Yinkun Fu, Pin-Ji Lei, Yanhua Yao, Wanli Yang, Ying Zhang, Michael P Washburn, Laurence Florens, Manish Jaiswal, Min Wu & Man Mohan. (2018) DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers. Nucleic Acids Research 46:21, pages 11202-11213.
Crossref
Vahid Bemanian, John Christopher Noone, Torill Sauer, Joel Touma, Katja Vetvik, Cecilia Søderberg-Naucler, Jonas Christoffer Lindstrøm, Ida Rashida Bukholm, Vessela N. Kristensen & Jürgen Geisler. (2018) Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer. Breast Cancer Research and Treatment 172:2, pages 339-351.
Crossref
Sambit Roy, Divya Gandra, Christina Seger, Anindita Biswas, Vitaly A Kushnir, Norbert Gleicher, T Rajendra Kumar & Aritro Sen. (2018) Oocyte-Derived Factors (GDF9 and BMP15) and FSH Regulate AMH Expression Via Modulation of H3K27AC in Granulosa Cells. Endocrinology 159:9, pages 3433-3445.
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Bradly M. Bauman, Chang Jeong, Matthew Savage, Anna L. Briker, Nicholas G. Janigian, Linda L. Nguyen, Zachary A. Kemmerer & Aimee L. Eggler. (2018) Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accumulation. Free Radical Biology and Medicine 124, pages 532-540.
Crossref
Stephanie Kaypee, Smitha Asoka Sahadevan, Deepthi Sudarshan, Sarmistha Halder Sinha, Shilpa Patil, Parijat Senapati, Gopinath S. Kodaganur, Azeem Mohiyuddin, Dipak Dasgupta & Tapas K. Kundu. (2018) Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation. Biochimica et Biophysica Acta (BBA) - General Subjects 1862:8, pages 1729-1741.
Crossref
Andrew Sulaiman, Sarah McGarry, Ka Mien Lam, Sara El-Sahli, Jason Chambers, Shelby Kaczmarek, Li Li, Christina Addison, Jim Dimitroulakos, Angel Arnaout, Carolyn Nessim, Zemin Yao, Guang Ji, Haiyan Song, Sheng Liu, Ying Xie, Suresh Gadde, Xuguang Li & Lisheng Wang. (2018) Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells. Cell Death & Disease 9:8.
Crossref
Changwei Dou, Zhikui Liu, Kangsheng Tu, Hongbin Zhang, Chen Chen, Usman Yaqoob, Yuanguo Wang, Jialing Wen, Jan van Deursen, Delphine Sicard, Daniel Tschumperlin, Hongzhi Zou, Wei-Chien Huang, Raul Urrutia, Vijay H. Shah & Ningling Kang. (2018) P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts. Gastroenterology 154:8, pages 2209-2221.e14.
Crossref
Yongming Xue, Hong Wen & Xiaobing Shi. (2018) CBP/p300: intramolecular and intermolecular regulations. Frontiers in Biology 13:3, pages 168-179.
Crossref
Zhuofeng Ding, Jiawei Cao, Yu Shen, Yu Zou, Xin Yang, Wen Zhou, Qulian Guo & Changsheng Huang. (2018) Resveratrol Promotes Nerve Regeneration via Activation of p300 Acetyltransferase-Mediated VEGF Signaling in a Rat Model of Sciatic Nerve Crush Injury. Frontiers in Neuroscience 12.
Crossref
L. Yan, Z. Shen & Z. Lu. (2018) Increases in the expression of Na + /H + exchanger 1 and 3 are associated with insulin signalling in the ruminal epithelium . Journal of Animal Physiology and Animal Nutrition 102:2, pages e569-e577.
Crossref
Tomoshige Kino. (2018) GR-regulating Serine/Threonine Kinases: New Physiologic and Pathologic Implications. Trends in Endocrinology & Metabolism 29:4, pages 260-270.
Crossref
Alexander Y. Deneka, Jason D. Howard & Christine H. Chung. 2018. Molecular Determinants of Head and Neck Cancer. Molecular Determinants of Head and Neck Cancer 117 154 .
Osamu Tetsu & Frank McCormick. (2017) ETS‐targeted therapy: can it substitute for MEK inhibitors?. Clinical and Translational Medicine 6:1.
Crossref
Deguan Lv, Feng Jia, Yanli Hou, Youzhou Sang, Angel A. Alvarez, Weiwei Zhang, Wei-Qiang Gao, Bo Hu, Shi-Yuan Cheng, Jianwei Ge, Yanxin Li & Haizhong Feng. (2017) Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding. Cancer Research 77:22, pages 6190-6201.
Crossref
Wei Wan, Zhiyuan You, Yinfeng Xu, Li Zhou, Zhunlv Guan, Chao Peng, Catherine C.L. Wong, Hua Su, Tianhua Zhou, Hongguang Xia & Wei Liu. (2017) mTORC1 Phosphorylates Acetyltransferase p300 to Regulate Autophagy and Lipogenesis. Molecular Cell 68:2, pages 323-335.e6.
Crossref
Huicong Yang, Yiqun Huang, Yong Zou & Xudong Ma. (2017) Synergistic effects of phenylhexyl isothiocyanate and LY294002 on the PI3K/Akt signaling pathway in HL-60 cells. Oncology Letters 14:3, pages 3043-3050.
Crossref
Jennifer M. Spangle, Thomas M. Roberts & Jean J. Zhao. (2017) The emerging role of PI3K/AKT-mediated epigenetic regulation in cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1868:1, pages 123-131.
Crossref
Shao-Jung Li, Yu-Hsun Kao, Cheng-Chih Chung, Wei-Yu Chen, Wan-li Cheng & Yi-Jen Chen. (2017) Activated p300 acetyltransferase activity modulates aortic valvular calcification with osteogenic transdifferentiation and downregulation of Klotho. International Journal of Cardiology 232, pages 271-279.
Crossref
Marion Vanneste, Vincent Hanoux, Mohammed Bouakka & Pierre-Jacques Bonnamy. (2017) Hyaluronate synthase-2 overexpression alters estrogen dependence and induces histone deacetylase inhibitor-like effects on ER-driven genes in MCF7 breast tumor cells. Molecular and Cellular Endocrinology 444, pages 48-58.
Crossref
Tanwir Habib, Ameera Sadoun, Nancy Nader, Shigeru Suzuki, Wei Liu, Puthen V. Jithesh & Tomoshige Kino. (2017) AKT1 has dual actions on the glucocorticoid receptor by cooperating with 14-3-3. Molecular and Cellular Endocrinology 439, pages 431-443.
Crossref
Arthur ZimmermannArthur Zimmermann. 2017. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 1205 1213 .
Manti Guha, Satish Srinivasan, Kip Guja, Edison Mejia, Miguel Garcia-Diaz, F Brad Johnson, Gordon Ruthel, Brett A Kaufman, Eric F Rappaport, M Rebecca Glineburg, Ji-Kang Fang, Andres Klein Szanto, Hiroshi Nakagawa, Jeelan Basha, Tapas Kundu & Narayan G Avadhani. (2016) HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression. Cell Discovery 2:1.
Crossref
Jeong-Min Park & Tae-Hong Kang. (2016) Transcriptional and Posttranslational Regulation of Nucleotide Excision Repair: The Guardian of the Genome against Ultraviolet Radiation. International Journal of Molecular Sciences 17:11, pages 1840.
Crossref
Kyung-Sun HeoBradford C. BerkJun-ichi Abe. (2016) Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events . Antioxidants & Redox Signaling 25:7, pages 435-450.
Crossref
Peiye Shen, Xiaojun Feng, Xiaoying Zhang, Xiaoyang Huang, Shenglan Liu, Xia Lu, Jingyan Li, Jia You, Jing Lu, Zhuoming Li, Jiantao Ye & Peiqing Liu. (2016) SIRT6 suppresses phenylephrine-induced cardiomyocyte hypertrophy though inhibiting p300. Journal of Pharmacological Sciences 132:1, pages 31-40.
Crossref
Fan Liu, Lan Wang, Fabiana Perna & Stephen D. Nimer. (2016) Beyond transcription factors: how oncogenic signalling reshapes the epigenetic landscape. Nature Reviews Cancer 16:6, pages 359-372.
Crossref
David Paladino, Peibin Yue, Hideki Furuya, Jared Acoba, Charles J. Rosser & James Turkson. (2015) A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer. Oncotarget 7:6, pages 7253-7267.
Crossref
Tara Boulding, Fan Wu, Robert McCuaig, Jennifer Dunn, Christopher R. Sutton, Kristine Hardy, Wenjuan Tu, Amanda Bullman, Desmond Yip, Jane E. Dahlstrom & Sudha Rao. (2016) Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer. PLOS ONE 11:2, pages e0148065.
Crossref
Hamood AlSudais, Kawther Aabed, William Nicola, Katherine Dixon, Jihong Chen & Qiao Li. (2016) Retinoid X Receptor-selective Signaling in the Regulation of Akt/Protein Kinase B Isoform-specific Expression. Journal of Biological Chemistry 291:6, pages 3090-3099.
Crossref
Arthur ZimmermannArthur Zimmermann. 2016. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 1 9 .
D. Spina & C. P. Page. 2017. Pharmacology and Therapeutics of Asthma and COPD. Pharmacology and Therapeutics of Asthma and COPD 63 91 .
Seong-Su Han, Van S Tompkins, Dong-Ju Son, Sangwoo Han, Hwakyung Yun, Natalie L Kamberos, Casey L Dehoedt, Chunyan Gu, Carol Holman, Guido Tricot, Fenghuang Zhan & Siegfried Janz. (2015) CDKN1A and FANCD2 are potential oncotargets in Burkitt lymphoma and multiple myeloma. Experimental Hematology & Oncology 4:1.
Crossref
Jihong Chen, Yingjian Wang, Munerah Hamed, Natascha Lacroix & Qiao Li. (2015) Molecular Basis for the Regulation of Transcriptional Coactivator p300 in Myogenic Differentiation. Scientific Reports 5:1.
Crossref
Janyaporn Phuchareon, Frank McCormick, David W. Eisele & Osamu Tetsu. (2015) EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function. Proceedings of the National Academy of Sciences 112:29.
Crossref
Abbas Jafari, Majken S. Siersbaek, Li Chen, Diyako Qanie, Walid Zaher, Basem M. Abdallah & Moustapha Kassem. (2015) Pharmacological Inhibition of Protein Kinase G1 Enhances Bone Formation by Human Skeletal Stem Cells Through Activation of RhoA-Akt Signaling. Stem Cells 33:7, pages 2219-2231.
Crossref
Nymph Chan, Shikun He, Christine K. Spee, Keijiro Ishikawa & David R. Hinton. (2015) Attenuation of Choroidal Neovascularization by Histone Deacetylase Inhibitor. PLOS ONE 10:3, pages e0120587.
Crossref
Nicholas A. Wallace, Kristin Robinson, Heather L. Howie & Denise A. Galloway. (2015) β-HPV 5 and 8 E6 Disrupt Homology Dependent Double Strand Break Repair by Attenuating BRCA1 and BRCA2 Expression and Foci Formation. PLOS Pathogens 11:3, pages e1004687.
Crossref
Soline Aubry, William Shin, John F. Crary, Roger Lefort, Yasir H. Qureshi, Celine Lefebvre, Andrea Califano & Michael L. Shelanski. (2015) Assembly and Interrogation of Alzheimer’s Disease Genetic Networks Reveal Novel Regulators of Progression. PLOS ONE 10:3, pages e0120352.
Crossref
Yi Pan & Lennard P. Niles. (2015) Epigenetic mechanisms of melatonin action in human SH-SY5Y neuroblastoma cells. Molecular and Cellular Endocrinology 402, pages 57-63.
Crossref
Vivek Narayan, Kodihalli C. Ravindra, Chang Liao, Naveen Kaushal, Bradley A. Carlson & K. Sandeep Prabhu. (2015) Epigenetic regulation of inflammatory gene expression in macrophages by selenium. The Journal of Nutritional Biochemistry 26:2, pages 138-145.
Crossref
Bo Su, Tao Luo, Junjie Zhu, Jing Fu, Xiaofang Zhao, Lei Chen, Huilu Zhang, Yibin Ren, Lexing Yu, Xiaojun Yang, Mengchao Wu, Gensheng Feng, Shao Li, Yao Chen & Hongyang Wang. (2015) Interleukin‐1β/Iinterleukin‐1 receptor‐associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis. Hepatology 61:2, pages 585-597.
Crossref
Jing Fan, Kimberly A. Krautkramer, Jessica L. Feldman & John M. Denu. (2015) Metabolic Regulation of Histone Post-Translational Modifications. ACS Chemical Biology 10:1, pages 95-108.
Crossref
WOO-SUK CHOI, YONG-BAE SEO, PYUNG-GYUN SHIN, WOE-YEON KIM, SANG YEOL LEE, YOUNG-JU CHOI & GUN-DO KIM. (2015) Veratric acid inhibits iNOS expression through the regulation of PI3K activation and histone acetylation in LPS-stimulated RAW264.7 cells. International Journal of Molecular Medicine 35:1, pages 202-210.
Crossref
Mark D. Stewart, Vishnu C. Ramani & Ralph D. Sanderson. (2015) Shed Syndecan-1 Translocates to the Nucleus of Cells Delivering Growth Factors and Inhibiting Histone Acetylation. Journal of Biological Chemistry 290:2, pages 941-949.
Crossref
Tulin Ersahin, Nurcan Tuncbag & Rengul Cetin-Atalay. (2015) The PI3K/AKT/mTOR interactive pathway. Molecular BioSystems 11:7, pages 1946-1954.
Crossref
Madhuri Bhandaru, Gholamreza Safaee Ardekani, Guohong Zhang, Magdalena Martinka, Kevin J McElwee, Gang Li & Anand Rotte. (2014) A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma. BMC Cancer 14:1.
Crossref
Nilay Nandi, Lauren K. Tyra, Drew Stenesen & Helmut Krämer. (2014) Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy. Journal of Cell Biology 207:2, pages 253-268.
Crossref
Edwin ChenJong Sook AhnCharlie E. MassieDavid ClynesAnna L. Godfrey, Juan LiHyun Jung ParkJyoti Nangalia, Yvonne SilberAnn Mullally, Richard J. GibbonsAnthony R. Green. (2014) JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response. Proceedings of the National Academy of Sciences 111:42, pages 15190-15195.
Crossref
Andres Castillo, Lu Wang, Chihaya Koriyama, Yoshito Eizuru, King Jordan & Suminori Akiba. (2014) A systems biology analysis of the changes in gene expression via silencing of HPV-18 E1 expression in HeLa cells. Open Biology 4:10, pages 130119.
Crossref
Q. Liu, K. M. Turner, W. K. Alfred Yung, K. Chen & W. Zhang. (2014) Role of AKT signaling in DNA repair and clinical response to cancer therapy. Neuro-Oncology 16:10, pages 1313-1323.
Crossref
Quanri Jin, Hyo-Jong Lee, Hye-Young Min, John Kendal Smith, Su Jung Hwang, Young Mi Whang, Woo-Young Kim, Yeul Hong Kim & Ho-Young Lee. (2014) Transcriptional and posttranslational regulation of insulin-like growth factor binding protein-3 by Akt3. Carcinogenesis 35:10, pages 2232-2243.
Crossref
Xiangpeng Dai, Pengda Liu, Alan W. Lau, Yueyong Liu & Hiroyuki Inuzuka. (2014) Acetylation‐dependent regulation of essential iPS ‐inducing factors: a regulatory crossroad for pluripotency and tumorigenesis . Cancer Medicine 3:5, pages 1211-1224.
Crossref
Nicholas A. Wallace, Kristin Robinson & Denise A. Galloway. (2014) Beta Human Papillomavirus E6 Expression Inhibits Stabilization of p53 and Increases Tolerance of Genomic Instability. Journal of Virology 88:11, pages 6112-6127.
Crossref
Shao-An Wang, Chia-Yang Hung, Jian-Ying Chuang, Wen-Chang Chang, Tsung-I Hsu & Jan-Jong Hung. (2014) Phosphorylation of p300 increases its protein degradation to enhance the lung cancer progression. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:6, pages 1135-1149.
Crossref
H Yamaguchi, S-S Chang, J L Hsu & M-C Hung. (2013) Signaling cross-talk in the resistance to HER family receptor targeted therapy. Oncogene 33:9, pages 1073-1081.
Crossref
C.P. Page & Domenico Spina. 2014. Middleton's Allergy. Middleton's Allergy 1542 1551 .
Jason D. Howard & Christine H. Chung. 2014. Molecular Determinants of Head and Neck Cancer. Molecular Determinants of Head and Neck Cancer 131 161 .
Xiaoxue Xie, Hui Wang, Hekun Jin, Shuyu Ouyang, Jumei Zhou, Jun Hu, Xuping Xi, Junming Luo, Yingying Zhang & Bingqiang Hu. (2013) Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma. Radiation Oncology 8:1.
Crossref
Anand Rotte, Madhuri Bhandaru, Yabin Cheng, Cecilia Sjoestroem, Magdalena Martinka & Gang Li. (2013) Decreased Expression of Nuclear p300 Is Associated with Disease Progression and Worse Prognosis of Melanoma Patients. PLoS ONE 8:9, pages e75405.
Crossref
Delphine GomezKetty KesslerJean-Baptiste MichelRoger Vranckx. (2013) Modifications of Chromatin Dynamics Control Smad2 Pathway Activation in Aneurysmal Smooth Muscle Cells. Circulation Research 113:7, pages 881-890.
Crossref
Jun TakaiAlexandra SantuHaifeng ZhengSang Don KohMasanori Ohta, Linda M. FilimbanVincent LemaîtreRyutaro TeraokaHanjoong Jo & Hiroto Miura. (2013) Laminar shear stress upregulates endothelial Ca 2+ -activated K + channels KCa2.3 and KCa3.1 via a Ca 2+ /calmodulin-dependent protein kinase kinase/Akt/p300 cascade . American Journal of Physiology-Heart and Circulatory Physiology 305:4, pages H484-H493.
Crossref
Hsin-Shan Yu, Tien-Huang Lin & Chih-Hsin Tang. (2013) Involvement of Intercellular Adhesion Molecule-1 Up-Regulation in Bradykinin Promotes Cell Motility in Human Prostate Cancers. International Journal of Molecular Sciences 14:7, pages 13329-13345.
Crossref
Mitsuo KatoVarun DangMei WangJung Tak ParkSupriya DeshpandeSwati KadamArmen MardirosYumei ZhanPeter OettgenSumanth PuttaHang YuanLinda LantingRama Natarajan. (2013) TGF-β Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy. Science Signaling 6:278.
Crossref
Min Huan Wu, Li-Mien Chen, His-Hsien Hsu, James A. Lin, Yueh-Min Lin, Fuu-Jen Tsai, Chang-Hai Tsai, Chih-Yang Huang & Chih-Hsin Tang. (2013) Endothelin-1 enhances cell migration through COX-2 up-regulation in human chondrosarcoma. Biochimica et Biophysica Acta (BBA) - General Subjects 1830:6, pages 3355-3364.
Crossref
Yan Liu, Zhao-bin Xing, Jing-hua Zhang & Yue Fang. (2013) Akt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18. FEBS Letters 587:7, pages 847-853.
Crossref
Aimee I. Badeaux & Yang Shi. (2013) Emerging roles for chromatin as a signal integration and storage platform. Nature Reviews Molecular Cell Biology 14:4, pages 211-224.
Crossref
Jeffrey P. Solzak, Yun Liang, Feng C. Zhou & Randall J. Roper. (2013) Commonality in Down and fetal alcohol syndromes. Birth Defects Research Part A: Clinical and Molecular Teratology 97:4, pages 187-197.
Crossref
Qi-En Wang, Chunhua Han, Ran Zhao, Gulzar Wani, Qianzheng Zhu, Li Gong, Aruna Battu, Ira Racoma, Nidhi Sharma & Altaf A. Wani. (2013) p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair. Nucleic Acids Research 41:3, pages 1722-1733.
Crossref
Yu-Min Lin, Zi-Ling Chang, Yuan-Ya Liao, Ming-Chih Chou & Chih-Hsin Tang. (2013) IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma. Cancer Letters 328:1, pages 135-143.
Crossref
Alberto M. Martelli, Giovanna Tabellini, Daniela Bressanin, Andrea Ognibene, Kaoru Goto, Lucio Cocco & Camilla Evangelisti. (2012) The emerging multiple roles of nuclear Akt. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:12, pages 2168-2178.
Crossref
Zhiwei Wang, Hiroyuki Inuzuka, Jiateng Zhong, Pengda Liu, Fazlul H. Sarkar, Yi Sun & Wenyi Wei. (2012) Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2. Oncotarget 3:11, pages 1294-1300.
Crossref
Te‐Mao Li, Chi‐Ming Wu, Hsin‐Chih Huang, Pei‐Chi Chou, Yi‐Chin Fong & Chih‐Hsin Tang. (2012) Interleukin‐11 Increases Cell Motility and Up‐Regulates Intercellular Adhesion Molecule‐1 Expression in Human Chondrosarcoma Cells. Journal of Cellular Biochemistry 113:11, pages 3353-3362.
Crossref
Anuraag Shrivastav & Leigh Murphy. (2012) Interactions of PI3K/Akt/mTOR and estrogen receptor signaling in breast cancer. Breast Cancer Management 1:3, pages 235-249.
Crossref
Chih-Chung LinI-Ta LeeWan-Ling Wu, Wei-Ning Lin & Chuen-Mao Yang. (2012) Adenosine triphosphate regulates NADPH oxidase activity leading to hydrogen peroxide production and COX-2/PGE 2 expression in A549 cells . American Journal of Physiology-Lung Cellular and Molecular Physiology 303:5, pages L401-L412.
Crossref
Chih-Hsin Tang, Yun-Ting Keng & Ju-Fang Liu. (2012) HMGB-1 induces cell motility and α5β1 integrin expression in human chondrosarcoma cells. Cancer Letters 322:1, pages 98-106.
Crossref
Hiroyuki Inuzuka, Daming Gao, Lydia W.S. Finley, Wen Yang, Lixin Wan, Hidefumi Fukushima, Y. Rebecca Chin, Bo Zhai, Shavali Shaik, Alan W. Lau, Zhiwei Wang, Steven P. Gygi, Keiko Nakayama, Julie Teruya-Feldstein, Alex Toker, Marcia C. Haigis, Pier Paolo Pandolfi & Wenyi Wei. (2012) Acetylation-Dependent Regulation of Skp2 Function. Cell 150:1, pages 179-193.
Crossref
Jing-Yuan Chuang, Nuo-Yi Yu, I-Ping Chiang, Chih-Ho Lai, Chia-Der Lin & Chih-Hsin Tang. (2012) Cyr61 increases matrix metalloproteinase-3 expression and cell motility in human oral squamous cell carcinoma cells. Journal of Cellular Biochemistry 113:6, pages 1977-1986.
Crossref
Therese M. Becker. 2006. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Encyclopedia of Molecular Cell Biology and Molecular Medicine.
Hong Ma, Mingquan Guo, Baoen Shan & Zanxian Xia. (2012) Targeted functional analysis of p300 coactivator in Wnt/β-catenin signaling pathway using phosphoproteomic and biochemical approaches. Journal of Proteomics 75:9, pages 2601-2610.
Crossref
Yi-Shiou Chiou, Nianhan Jia-Lin Ma, Shengmin Sang, Chi-Tang Ho, Ying-Jan Wang & Min-Hsiung Pan. (2012) Peracetylated (−)-Epigallocatechin-3-gallate (AcEGCG) Potently Suppresses Dextran Sulfate Sodium-Induced Colitis and Colon Tumorigenesis in Mice. Journal of Agricultural and Food Chemistry 60:13, pages 3441-3451.
Crossref
Yi-Chin Fong, Chih-Yang Lin, Yi-Chang Su, Wen-Chi Chen, Fuu-Jen Tsai, Chang-Hai Tsai, Chih-Yang Huang & Chih-Hsin Tang. (2012) CCN6 enhances ICAM-1 expression and cell motility in human chondrosarcoma cells. Journal of Cellular Physiology 227:1, pages 223-232.
Crossref
Pei-Ling Chi, Shue-Fen Luo, Hsi-Lung Hsieh, I-Ta Lee, Li-Der Hsiao, Yuh-Lien Chen & Chuen-Mao Yang. (2011) Cytosolic phospholipase A 2 induction and prostaglandin E 2 release by interleukin-1β via the myeloid differentiation factor 88-dependent pathway and cooperation of p300, Akt, and NF-κB activity in human rheumatoid arthritis synovial fibroblasts . Arthritis & Rheumatism 63:10, pages 2905-2917.
Crossref
Heather L. Howie, Jennifer I. Koop, Joleen Weese, Kristin Robinson, Greg Wipf, Leslie Kim & Denise A. Galloway. (2011) Beta-HPV 5 and 8 E6 Promote p300 Degradation by Blocking AKT/p300 Association. PLoS Pathogens 7:8, pages e1002211.
Crossref
J. D. Meissner, R. Freund, D. Krone, P. K. Umeda, K.-C. Chang, G. Gros & R. J. Scheibe. (2011) Extracellular signal-regulated kinase 1/2-mediated phosphorylation of p300 enhances myosin heavy chain I/  gene expression via acetylation of nuclear factor of activated T cells c1. Nucleic Acids Research 39:14, pages 5907-5925.
Crossref
Jing-Yuan Chuang, Wan-Yu Yang, Chih-Ho Lai, Chia-Der Lin, Ming-Hsui Tsai & Chih-Hsin Tang. (2011) CTGF inhibits cell motility and COX-2 expression in oral cancer cells. International Immunopharmacology 11:8, pages 948-954.
Crossref
Emily Turner-Brannen, Ka-Yee Grace Choi, Ryan Arsenault, Hani El-Gabalawy, Scott Napper & Neeloffer Mookherjee. (2011) Inflammatory Cytokines IL-32 and IL-17 Have Common Signaling Intermediates despite Differential Dependence on TNF-Receptor 1. The Journal of Immunology 186:12, pages 7127-7135.
Crossref
Ashraf Said Al Madhoun, Virja Mehta, Grace Li, Daniel Figeys, Nadine Wiper-Bergeron & Ilona S Skerjanc. (2011) Skeletal myosin light chain kinase regulates skeletal myogenesis by phosphorylation of MEF2C. The EMBO Journal 30:12, pages 2477-2489.
Crossref
Sarah M. Senf, Pooja B. Sandesara, Sarah A. Reed & Andrew R. Judge. (2011) p300 Acetyltransferase activity differentially regulates the localization and activity of the FOXO homologues in skeletal muscle. American Journal of Physiology-Cell Physiology 300:6, pages C1490-C1501.
Crossref
Wei-Chien Huang, Yun-Ju Chen, Long-Yuan Li, Ya-Ling Wei, Sheng-Chieh Hsu, Shing-Ling Tsai, Pei-Chun Chiu, Wei-Pang Huang, Ying-Nai Wang, Chung-Hsuan Chen, Wei-Chao Chang, Wen-Chang Chang, Andy Jer-En Chen, Chang-Hai Tsai & Mien-Chie Hung. (2011) Nuclear Translocation of Epidermal Growth Factor Receptor by Akt-dependent Phosphorylation Enhances Breast Cancer-resistant Protein Expression in Gefitinib-resistant Cells. Journal of Biological Chemistry 286:23, pages 20558-20568.
Crossref
Carl F. Fortin, Alexandre Cloutier, Thornin Ear, Stéphanie Sylvain-Prévost, Thomas Z. Mayer, Rim Bouchelaghem & Patrick P. McDonald. (2011) A class IA PI3K controls inflammatory cytokine production in human neutrophils. European Journal of Immunology 41:6, pages 1709-1719.
Crossref
Che-Yi Chao, Chong-Kuei Lii, I-Ting Tsai, Chien−Chun Li, Kai-Li Liu, Chia-Wen Tsai & Haw-Wen Chen. (2011) Andrographolide Inhibits ICAM-1 Expression and NF-κB Activation in TNF-α-Treated EA.hy926 Cells. Journal of Agricultural and Food Chemistry 59:10, pages 5263-5271.
Crossref
Sung Hee Baek. (2011) When Signaling Kinases Meet Histones and Histone Modifiers in the Nucleus. Molecular Cell 42:3, pages 274-284.
Crossref
Li-Mien Chen, Chia-Hua Kuo, Tung-Yuan Lai, Yueh-Min Lin, Cheng-Chuan Su, His-Hsien Hsu, Fuu-Jen Tsai, Chang-Hai Tsai, Chih-Yang Huang & Chih-Hsin Tang. (2011) RANKL increases migration of human lung cancer cells through intercellular adhesion molecule-1 up-regulation. Journal of Cellular Biochemistry 112:3, pages 933-941.
Crossref
Seong-Su Han, Hwakyung Yun, Dong-Ju Son, Van S. Tompkins, Liangping Peng, Seung-Tae Chung, Joong-Su Kim, Eun-Sung Park & Siegfried Janz. (2010) NF-κB/STAT3/PI3K signaling crosstalk in iMycEμ B lymphoma. Molecular Cancer 9:1.
Crossref
Manti Guha, Ji-Kang Fang, Robert Monks, Morris J. Birnbaum & Narayan G. Avadhani. (2010) Activation of Akt Is Essential for the Propagation of Mitochondrial Respiratory Stress Signaling and Activation of the Transcriptional Coactivator Heterogeneous Ribonucleoprotein A2. Molecular Biology of the Cell 21:20, pages 3578-3589.
Crossref
Mohammed Arif, Parijat Senapati, Jayasha Shandilya & Tapas K. Kundu. (2010) Protein lysine acetylation in cellular function and its role in cancer manifestation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1799:10-12, pages 702-716.
Crossref
Shun-Fa Yang, Mu-Kuan Chen, Yih-Shou Hsieh, Tsung-Te Chung, Yi-Hsien Hsieh, Chiao-Wen Lin, Jen-Liang Su, Ming-Hsui Tsai & Chih-Hsin Tang. (2010) Prostaglandin E2/EP1 Signaling Pathway Enhances Intercellular Adhesion Molecule 1 (ICAM-1) Expression and Cell Motility in Oral Cancer Cells. Journal of Biological Chemistry 285:39, pages 29808-29816.
Crossref
Jason S. Patzlaff, Edith Terrenoire, Bryan M. Turner, William C. Earnshaw & James R. Paulson. (2010) Acetylation of core histones in response to HDAC inhibitors is diminished in mitotic HeLa cells. Experimental Cell Research 316:13, pages 2123-2135.
Crossref
Mohammed Arif, Bhusainahalli M. Vedamurthy, Ramesh Choudhari, Yogesh B. Ostwal, Kempegowda Mantelingu, Gopinath S. Kodaganur & Tapas K. Kundu. (2010) Nitric Oxide-Mediated Histone Hyperacetylation in Oral Cancer: Target for a Water-Soluble HAT Inhibitor, CTK7A. Chemistry & Biology 17:8, pages 903-913.
Crossref
Sang-pil Kim, Jung Min Ha, Sung Ji Yun, Eun Kyoung Kim, Sung Woon Chung, Ki Whan Hong, Chi Dae Kim & Sun Sik Bae. (2010) Transcriptional activation of peroxisome proliferator-activated receptor-γ requires activation of both protein kinase A and Akt during adipocyte differentiation. Biochemical and Biophysical Research Communications 399:1, pages 55-59.
Crossref
I-Ta Lee, Chih-Chung Lin, Yang-Chang Wu & Chuen-Mao Yang. (2010) TNF-α induces matrix metalloproteinase-9 expression in A549 cells: Role of TNFR1/TRAF2/PKCα-dependent signaling pathways. Journal of Cellular Physiology 224:2, pages 454-464.
Crossref
R Suvasini & K Somasundaram. (2010) Essential role of PI3-kinase pathway in p53-mediated transcription: Implications in cancer chemotherapy. Oncogene 29:25, pages 3605-3618.
Crossref
Catherine Ibarra Drendall, Quang H. Pham & Eric C. Dietze. (2010) Purification and characterization of recombinant CH3 domain fragment of the CREB-binding protein. Protein Expression and Purification 70:2, pages 196-205.
Crossref
Yoichi Sunagawa, Tatsuya Morimoto, Tomohide Takaya, Shinji Kaichi, Hiromichi Wada, Teruhisa Kawamura, Masatoshi Fujita, Akira Shimatsu, Toru Kita & Koji Hasegawa. (2010) Cyclin-dependent Kinase-9 Is a Component of the p300/GATA4 Complex Required for Phenylephrine-induced Hypertrophy in Cardiomyocytes. Journal of Biological Chemistry 285:13, pages 9556-9568.
Crossref
Julien Yockell-LelièvreCorentin SprietPaule CantinPatrick MalenfantLaurent HeliotYvan de LaunoitMarie Audette. (2009) Functional cooperation between Stat-1 and ets-1 to optimize icam-1 gene transcription . Biochemistry and Cell Biology 87:6, pages 905-918.
Crossref
Jing-Yi Chen, Ming-Chung Wang & Wen-Chun Hung. (2009) Transcriptional activation of Skp2 by BCR-ABL in K562 chronic myeloid leukemia cells. Leukemia Research 33:11, pages 1520-1524.
Crossref
Armina A. Kazi, Kristin Happ Molitoris & Robert D. Koos. (2009) Estrogen Rapidly Activates the PI3K/AKT Pathway and Hypoxia-Inducible Factor 1 and Induces Vascular Endothelial Growth Factor A Expression in Luminal Epithelial Cells of the Rat Uterus1. Biology of Reproduction 81:2, pages 378-387.
Crossref
Meng-Hsiu Chiang, Feng-Yu Liang, Chie-Pein Chen, Ching-Wen Chang, Mei-Leng Cheong, Liang-Jie Wang, Ching-Yeu Liang, Fang-Yu Lin, Chih-Chine Chou & Hungwen Chen. (2009) Mechanism of Hypoxia-induced GCM1 Degradation. Journal of Biological Chemistry 284:26, pages 17411-17419.
Crossref
Fun Yu, Chia-Wei Chou & Ching-Chow Chen. (2009) TNF-α suppressed TGF-β-induced CTGF expression by switching the binding preference of p300 from Smad4 to p65. Cellular Signalling 21:6, pages 867-872.
Crossref
Su-Jin Kim, Cuilan Nian & Christopher H.S. McIntosh. (2009) Glucose-dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 Modulate β-Cell Chromatin Structure. Journal of Biological Chemistry 284:19, pages 12896-12904.
Crossref
Shue-Fen Luo, Chia-Chi Chang, I-Ta Lee, Chiang-Wen Lee, Wei-Ning Lin, Chih-Chung Lin & Chuen-Mao Yang. (2009) Activation of ROS/NF-κB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1β-treated human tracheal smooth muscle cells. Toxicology and Applied Pharmacology 237:1, pages 8-21.
Crossref
Kensuke Sakamoto, Kenta Iwasaki, Hiroyuki Sugiyama & Yoshiaki Tsuji. (2009) Role of the Tumor Suppressor PTEN in Antioxidant Responsive Element-mediated Transcription and Associated Histone Modifications. Molecular Biology of the Cell 20:6, pages 1606-1617.
Crossref
Julie Lodewick, Isabelle Lamsoul, Angela Polania, Sylvie Lebrun, Arsène Burny, Lee Ratner & Françoise Bex. (2009) Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-κB pathway. Virology 386:1, pages 68-78.
Crossref
R. Magnus N. Friis & Michael C. Schultz. (2009) Untargeted tail acetylation of histones in chromatin: lessons from yeastThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.. Biochemistry and Cell Biology 87:1, pages 107-116.
Crossref
Derek J.C. Tai, Chia-Chen Su, Yun-Li Ma & Eminy H.Y. Lee. (2009) SGK1 Phosphorylation of IκB Kinase α and p300 Up-regulates NF-κB Activity and Increases N-Methyl-D-aspartate Receptor NR2A and NR2B Expression. Journal of Biological Chemistry 284:7, pages 4073-4089.
Crossref
Zhi Wang, Guotong Xu, Yalan Wu, Yuan Guan, Lu Cui, Xia Lei, Jingfa Zhang, Lisha Mou, Baogui Sun & Qiuyan Dai. (2008) Neuregulin-1 enhances differentiation of cardiomyocytes from embryonic stem cells. Medical & Biological Engineering & Computing 47:1, pages 41-48.
Crossref
Chia-Wei Chou & Ching-Chow Chen. (2008) HDAC inhibition upregulates the expression of angiostatic ADAMTS1. FEBS Letters 582:29, pages 4059-4065.
Crossref
Beata Madziar, Sonia Shah, Martina Brock, Rebecca Burke, Ignacio Lopez-Coviella, Ann-Christin Nickel, Esra Betul Cakal, Jan Krzysztof Blusztajn & Brygida Berse. (2008) Nerve growth factor regulates the expression of the cholinergic locus and the high-affinity choline transporter via the Akt/PKB signaling pathway. Journal of Neurochemistry 107:5, pages 1284-1293.
Crossref
Toshinobu Nakamura, Kimiko Inoue, Shoko Ogawa, Hiroki Umehara, Narumi Ogonuki, Hiromi Miki, Tohru Kimura, Atsuo Ogura & Toru Nakano. (2008) Effects of Akt signaling on nuclear reprogramming. Genes to Cells 13:12, pages 1269-1277.
Crossref
M. R. Bratton, D. E. Frigo, K. A. Vigh-Conrad, D. Fan, S. Wadsworth, J. A. McLachlan & M. E. Burow. (2008) Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated protein kinase. Carcinogenesis 30:1, pages 106-113.
Crossref
Jian Qin WeiLina A. ShehadehJames M. MitraniMonica PessanhaTatiana I. SlepakKeith A. WebsterNanette H. Bishopric. (2008) Quantitative Control of Adaptive Cardiac Hypertrophy by Acetyltransferase p300. Circulation 118:9, pages 934-946.
Crossref
Santhosh Palani & Casim A. Sarkar. (2008) Positive Receptor Feedback during Lineage Commitment Can Generate Ultrasensitivity to Ligand and Confer Robustness to a Bistable Switch. Biophysical Journal 95:4, pages 1575-1589.
Crossref
Martin Savard, David Barbaz, Simon Bélanger, Werner Müller-Esterl, Ghassan Bkaily, Pedro D'orléans-Juste, Jérôme Coté, Veronica Bovenzi & Fernand GobeilJrJr. (2008) Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation. Journal of Cellular Physiology 216:1, pages 234-244.
Crossref
Feng-Qian Li, Adaobi Mofunanya, Kimberley Harris & Ken-Ichi Takemaru. (2008) Chibby cooperates with 14-3-3 to regulate β-catenin subcellular distribution and signaling activity. Journal of Cell Biology 181:7, pages 1141-1154.
Crossref
Wei Chen, Methode Bacanamwo & David G. Harrison. (2008) Activation of p300 Histone Acetyltransferase Activity Is an Early Endothelial Response to Laminar Shear Stress and Is Essential for Stimulation of Endothelial Nitric-oxide Synthase mRNA Transcription. Journal of Biological Chemistry 283:24, pages 16293-16298.
Crossref
Weimin Peng, Cynthia Togawa, Kangling Zhang & Siavash K Kurdistani. (2008) Regulators of Cellular Levels of Histone Acetylation in Saccharomyces cerevisiae . Genetics 179:1, pages 277-289.
Crossref
Chiang-Wen Lee, Chih-Chung Lin, Shue-Fen Luo, Hui-Chun Lee, I.-Ta Lee, William C. Aird, Tsong-Long Hwang & Chuen-Mao Yang. (2008) Tumor Necrosis Factor-α Enhances Neutrophil Adhesiveness: Induction of Vascular Cell Adhesion Molecule-1 via Activation of Akt and CaM Kinase II and Modifications of Histone Acetyltransferase and Histone Deacetylase 4 in Human Tracheal Smooth Muscle Cells. Molecular Pharmacology 73:5, pages 1454-1464.
Crossref
Cheng-Ying Wu, Hsi-Lung Hsieh, Chi-Chin Sun, Ching-Ping Tseng & Chuen-Mao Yang. (2008) IL-1β induces proMMP-9 expression via c-Src-dependent PDGFR/PI3K/Akt/p300 cascade in rat brain astrocytes. Journal of Neurochemistry 105:4, pages 1499-1512.
Crossref
Naoko Kanda & Shinichi Watanabe. (2007) Histamine enhances the production of human β-defensin-2 in human keratinocytes. American Journal of Physiology-Cell Physiology 293:6, pages C1916-C1923.
Crossref
Asish K Ghosh & John Varga. (2007) The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis. Journal of Cellular Physiology 213:3, pages 663-671.
Crossref
J. M. McClung, A. N. Kavazis, M. A. Whidden, K. C. DeRuisseau, D. J. Falk, D. S. Criswell & S. K. Powers. (2007) Antioxidant administration attenuates mechanical ventilation-induced rat diaphragm muscle atrophy independent of protein kinase B (PKB-Akt) signalling. The Journal of Physiology 585:1, pages 203-215.
Crossref
Liu-Ya Tang, Ning Deng, Lian-Shui Wang, Jie Dai, Zheng-Long Wang, Xiao-Sheng Jiang, Su-Jun Li, Long Li, Quan-Hu Sheng, Dian-Qing Wu, Lin Li & Rong Zeng. (2007) Quantitative Phosphoproteome Profiling of Wnt3a-mediated Signaling Network. Molecular & Cellular Proteomics 6:11, pages 1952-1967.
Crossref
Carlo Serra, Daniela Palacios, Chiara Mozzetta, Sonia V. Forcales, Ianessa Morantte, Meri Ripani, David R. Jones, Keyong Du, Ulupi S. Jhala, Cristiano Simone & Pier Lorenzo Puri. (2007) Functional Interdependence at the Chromatin Level between the MKK6/p38 and IGF1/PI3K/AKT Pathways during Muscle Differentiation. Molecular Cell 28:2, pages 200-213.
Crossref
Yung-Cheng Chiu, Rong-Sen Yang, Kuo-Hsien Hsieh, Yi-Chin Fong, Tzong-Der Way, Tu-Sheng Lee, Hsi-Chin Wu, Wen-Mei Fu & Chih-Hsin Tang. (2007) Stromal Cell-Derived Factor-1 Induces Matrix Metalloprotease-13 Expression in Human Chondrocytes. Molecular Pharmacology 72:3, pages 695-703.
Crossref
Yun-Ju Chen, Ying-Nai Wang & Wen-Chang Chang. (2007) ERK2-mediated C-terminal Serine Phosphorylation of p300 Is Vital to the Regulation of Epidermal Growth Factor-induced Keratin 16 Gene Expression. Journal of Biological Chemistry 282:37, pages 27215-27228.
Crossref
Chih-Hsin Tang, Dah-Yuu Lu, Tzu-Wei Tan, Wen-Mei Fu & Rong-Sen Yang. (2007) Ultrasound Induces Hypoxia-inducible Factor-1 Activation and Inducible Nitric-oxide Synthase Expression through the Integrin/Integrin-linked Kinase/Akt/Mammalian Target of Rapamycin Pathway in Osteoblasts. Journal of Biological Chemistry 282:35, pages 25406-25415.
Crossref
Chien-Ping LiangSeongah HanTakafumi SenokuchiAlan R. Tall. (2007) The Macrophage at the Crossroads of Insulin Resistance and Atherosclerosis. Circulation Research 100:11, pages 1546-1555.
Crossref
Chih-Chung Lin, Chiang-Wen Lee, Tzu-Hua Chu, Ching-Yi Cheng, Shue-Fen Luo, Li-Der Hsiao & Chuen-Mao Yang. (2007) Transactivation of Src, PDGF receptor, and Akt is involved in IL-1β-induced ICAM-1 expression in A549 cells. Journal of Cellular Physiology 211:3, pages 771-780.
Crossref
Pedro A. Ruiz, Annett Braune, Gabriele Hölzlwimmer, Leticia Quintanilla-Fend & Dirk Haller. (2007) Quercetin Inhibits TNF-Induced NF-κB Transcription Factor Recruitment to Proinflammatory Gene Promoters in Murine Intestinal Epithelial Cells. The Journal of Nutrition 137:5, pages 1208-1215.
Crossref
Michalis V Karamouzis, Panagiotis A Konstantinopoulos & Athanasios G Papavassiliou. (2007) Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis. Cell Research 17:4, pages 324-332.
Crossref
Wei-Chien Huang, Tsai-Kai Ju, Mien-Chie Hung & Ching-Chow Chen. (2007) Phosphorylation of CBP by IKKα Promotes Cell Growth by Switching the Binding Preference of CBP from p53 to NF-κB. Molecular Cell 26:1, pages 75-87.
Crossref
Chiang-Wen Lee, Chih-Chung Lin, Wei-Ning Lin, Kao-Chih Liang, Shue-Feng Luo, Chow-Bin Wu, Shyi-Wu Wang & Chuen-Mao Yang. (2007) TNF-α induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-κB/p300 binding in human tracheal smooth muscle cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 292:3, pages L799-L812.
Crossref
Cristiana Roggia, Christian Ukena, Michael Böhm & Heiko Kilter. (2007) Hepatocyte growth factor (HGF) enhances cardiac commitment of differentiating embryonic stem cells by activating PI3 kinase. Experimental Cell Research 313:5, pages 921-930.
Crossref
Mélanie Sanchez, Karine Sauvé, Nathalie Picard & André Tremblay. (2007) The Hormonal Response of Estrogen Receptor β Is Decreased by the Phosphatidylinositol 3-Kinase/Akt Pathway via a Phosphorylation-dependent Release of CREB-binding Protein. Journal of Biological Chemistry 282:7, pages 4830-4840.
Crossref
Satomi Kato & Keyong Du. (2007) TRB3 modulates C2C12 differentiation by interfering with Akt activation. Biochemical and Biophysical Research Communications 353:4, pages 933-938.
Crossref
Norihiko Ohbayashi, Osamu Ikeda, Naohisa Taira, Yu Yamamoto, Ryuta Muromoto, Yuichi Sekine, Kenji Sugiyama, Tsutomu HonjohTadashi Matsuda. (2007) LIF- and IL-6-Induced Acetylation of STAT3 at Lys-685 through PI3K/Akt Activation. Biological and Pharmaceutical Bulletin 30:10, pages 1860-1864.
Crossref
Lata Balakrishnan & Barry Milavetz. (2007) Histone Hyperacetylation in the Coding Region of Chromatin Undergoing Transcription in SV40 Minichromosomes Is a Dynamic Process Regulated Directly by the Presence of RNA Polymerase II. Journal of Molecular Biology 365:1, pages 18-30.
Crossref
Jihong Chen, Feras M Ghazawi, Wafae Bakkar & Qiao Li. (2006) Valproic acid and butyrate induce apoptosis in human cancer cells through inhibition of gene expression of Akt/protein kinase B. Molecular Cancer 5:1.
Crossref

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