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Molecular and Cellular Biology Volume 25, 2005 - Issue 16
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Gene Expression

Identification of Splicing Silencers and Enhancers in Sense Alus: a Role for Pseudoacceptors in Splice Site Repression

Haixin Lei1 University of Southampton School of Medicine, Division of Human Genetics, SouthamptonSO16 6YD, United Kingdom;2 Karolinska Institute at NOVUM, Department of Biosciences, S-141 57Huddinge, Sweden
&
Igor Vořechovský1 University of Southampton School of Medicine, Division of Human Genetics, SouthamptonSO16 6YD, United KingdomCorrespondence[email protected]
Pages 6912-6920 | Received 26 Feb 2005, Accepted 27 May 2005, Published online: 27 Mar 2023

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Jana Kralovicova, Alpa Patel, Mark Searle & Igor Vorechovsky. (2015) The role of short RNA loops in recognition of a single-hairpin exon derived from a mammalian-wide interspersed repeat. RNA Biology 12:1, pages 54-69.
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Articles from other publishers (26)

Jana Královičová, Ivana Borovská, Reuben Pengelly, Eunice Lee, Pavel Abaffy, Radek Šindelka, Frank Grutzner & Igor Vořechovský. (2021) Restriction of an intron size en route to endothermy . Nucleic Acids Research 49:5, pages 2460-2487.
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R. N Mustafin. (2021) Involvement of transposons in epigenetic regulation of embryogenesis. Genes & Cells 16:1, pages 10-14.
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Se-Hee Choe, Sang-Je Park, Hyeon-Mu Cho, Hye-Ri Park, Ja-Rang Lee, Young-Hyun Kim & Jae-Won Huh. (2020) A single mutation in the ACTR8 gene associated with lineage-specific expression in primates. BMC Evolutionary Biology 20:1.
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R. N. Mustafin & E. K. Khusnutdinova. (2019) The Role of Reverse Transcriptase in the Origin of Life. Biochemistry (Moscow) 84:8, pages 870-883.
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Ulrich H. Weidle, Ina Rohwedder, Fabian Birzele, Elisabeth H. Weiss & Christian Schiller. (2018) LST1: A multifunctional gene encoded in the MHC class III region. Immunobiology 223:11, pages 699-708.
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R. N. Mustafin & E. K. Khusnutdinova. (2018) The Role of Transposable Elements in Emergence of Metazoa. Biochemistry (Moscow) 83:3, pages 185-199.
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Ling-Ling Chen & Li Yang. (2017) ALU ternative Regulation for Gene Expression. Trends in Cell Biology 27:7, pages 480-490.
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Jana Kralovicova & Igor Vorechovsky. (2017) Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons . Nucleic Acids Research 45:1, pages 417-434.
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Jana KralovicovaPedro M.D. MorenoNicholas C.P. CrossAna Paula PêgoIgor Vorechovsky. (2016) Antisense Oligonucleotides Modulating Activation of a Nonsense-Mediated RNA Decay Switch Exon in the ATM Gene . Nucleic Acid Therapeutics 26:6, pages 392-400.
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Jana Kralovicova, Marcin Knut, Nicholas C. P. Cross & Igor Vorechovsky. (2016) Exon-centric regulation of ATM expression is population-dependent and amenable to antisense modification by pseudoexon targeting. Scientific Reports 6:1.
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Jana Kralovicova, Ana Lages, Alpa Patel, Ashish Dhir, Emanuele Buratti, Mark Searle & Igor Vorechovsky. (2014) Optimal antisense target reducing INS intron 1 retention is adjacent to a parallel G quadruplex . Nucleic Acids Research 42:12, pages 8161-8173.
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Olga Kelemen, Paolo Convertini, Zhaiyi Zhang, Yuan Wen, Manli Shen, Marina Falaleeva & Stefan Stamm. (2013) Function of alternative splicing. Gene 514:1, pages 1-30.
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Haixin Lei, Anusha P. Dias & Robin Reed. (2011) Export and stability of naturally intronless mRNAs require specific coding region sequences and the TREX mRNA export complex. Proceedings of the National Academy of Sciences 108:44, pages 17985-17990.
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Jana Kralovicova, Gyulin Hwang, A. Charlotta Asplund, Alexander Churbanov, C. I. Edvard Smith & Igor Vorechovsky. (2011) Compensatory signals associated with the activation of human GC 5′ splice sites. Nucleic Acids Research 39:16, pages 7077-7091.
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Michela Raponi, Jana Kralovicova, Ellen Copson, Petr Divina, Diana Eccles, Peter Johnson, Diana Baralle & Igor Vorechovsky. (2011) Prediction of single‐nucleotide substitutions that result in exon skipping: identification of a splicing silencer in BRCA1 exon 6 . Human Mutation 32:4, pages 436-444.
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Paula Moolhuijzen, Jerzy K. Kulski, David S. Dunn, David Schibeci, Roberto Barrero, Takashi Gojobori & Matthew Bellgard. (2010) The transcript repeat element: the human Alu sequence as a component of gene networks influencing cancer. Functional & Integrative Genomics 10:3, pages 307-319.
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David Meili, Jana Kralovicova, Julian Zagalak, Luisa Bonafé, Laura Fiori, Nenad Blau, Beat Thöny & Igor Vorechovsky. (2009) Disease-causing mutations improving the branch site and polypyrimidine tract: Pseudoexon activation of LINE-2 and antisense Alu lacking the poly(T)-tail . Human Mutation 30:5, pages 823-831.
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Rotem Sorek. (2007) The birth of new exons: Mechanisms and evolutionary consequences. RNA 13:10, pages 1603-1608.
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Jana Královičová & Igor Vořechovský. (2007) Global control of aberrant splice-site activation by auxiliary splicing sequences: evidence for a gradient in exon and intron definition. Nucleic Acids Research 35:19, pages 6399-6413.
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Zheqiong Yang, Yang Sui, Shiqin Xiong, Sean S. Liour, Andrew C. Phillips & Lan Ko. (2007) Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation. Nucleic Acids Research 35:6, pages 1919-1932.
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Gemma Mola, Elena Vela, Ma Teresa Fernández-Figueras, Marcos Isamat & Ana M. Muñoz-Mármol. (2007) Exonization of Alu-generated Splice Variants in the Survivin Gene of Human and Non-human Primates. Journal of Molecular Biology 366:4, pages 1055-1063.
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A.E. Illarionova, T.V. Vinogradova & E.D. Sverdlov. (2007) Only those genes of the KIAA1245 gene subfamily that contain HERV(K) LTRs in their introns are transcriptionally active. Virology 358:1, pages 39-47.
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Julien Häsler & Katharina Strub. (2006) Alu elements as regulators of gene expression. Nucleic Acids Research 34:19, pages 5491-5497.
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Jana Královičová, Haixin Lei & Igor Vořechovský. (2006) Phenotypic consequences of branch point substitutions. Human Mutation 27:8, pages 803-813.
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Jana Královic̆ová & Igor Vor̆echovský. (2006) Position-Dependent Repression and Promotion of DQB1 Intron 3 Splicing by GGGG Motifs . The Journal of Immunology 176:4, pages 2381-2388.
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J. Kralovicova, M. B. Christensen & I. Vorechovsky. (2005) Biased exon/intron distribution of cryptic and de novo 3' splice sites. Nucleic Acids Research 33:15, pages 4882-4898.
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