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Signal Transduction

AMP-Activated Protein Kinase Protects Cardiomyocytes against Hypoxic Injury through Attenuation of Endoplasmic Reticulum Stress

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Pages 9554-9575 | Received 06 Jun 2005, Accepted 16 Aug 2005, Published online: 27 Mar 2023

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Olivier A. PierratAnju PaudyalJames WoodruffOlga KorolevaSamuel Y. Boateng. (2017) The exon junction complex senses energetic stress and regulates contractility and cell architecture in cardiac myocytes. Bioscience Reports 37:4.
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M. L. Battson, D. M. Lee & C. L. Gentile. (2017) Endoplasmic reticulum stress and the development of endothelial dysfunction. American Journal of Physiology-Heart and Circulatory Physiology 312:3, pages H355-H367.
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Wenqi Yang, Xu Chen, Ming Chen, Yanping Li, Qing Li, Xinwei Jiang, Yan Yang & Wenhua Ling. (2017) Fish oil supplementation inhibits endoplasmic reticulum stress and improves insulin resistance: involvement of AMP-activated protein kinase. Food & Function 8:4, pages 1481-1493.
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Giada Zurlo, Jianping Guo, Mamoru Takada, Wenyi Wei & Qing Zhang. (2016) New Insights into Protein Hydroxylation and Its Important Role in Human Diseases. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1866:2, pages 208-220.
Crossref
Suresh C. Bairwa, Nirmal Parajuli & Jason R.B. Dyck. (2016) The role of AMPK in cardiomyocyte health and survival. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1862:12, pages 2199-2210.
Crossref
Yu Liu, Manli Yu, Zhigang Zhang, Yunhua Yu, Qi Chen, Wei Zhang & Xianxian Zhao. (2016) Blockade of receptor for advanced glycation end products protects against systolic overload-induced heart failure after transverse aortic constriction in mice. European Journal of Pharmacology 791, pages 535-543.
Crossref
Ying Wang, Yumeng Wan, Guihong Ye, Pu Wang, Xiaowen Xue, Guanzhong Wu & Boping Ye. (2016) Hepatoprotective effects of AdipoRon against d-galactosamine-induced liver injury in mice. European Journal of Pharmaceutical Sciences 93, pages 123-131.
Crossref
Wenguang Chang, Kun Li, Fengying Guan, Fan Yao, Yang Yu, Ming Zhang, Grant M. Hatch & Li Chen. (2016) Berberine Pretreatment Confers Cardioprotection Against Ischemia–Reperfusion Injury in a Rat Model of Type 2 Diabetes. Journal of Cardiovascular Pharmacology and Therapeutics 21:5, pages 486-494.
Crossref
Marcel Boß, Yvette Newbatt, Sahil Gupta, Ian Collins, Bernhard Brüne & Dmitry Namgaladze. (2016) AMPK-independent inhibition of human macrophage ER stress response by AICAR. Scientific Reports 6:1.
Crossref
Tomozumi Takatani, Jun Shirakawa, Michael W. Roe, Colin A. Leech, Bernhard F. Maier, Raghavendra G. Mirmira & Rohit N. Kulkarni. (2016) IRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation. Scientific Reports 6:1.
Crossref
WEIKUN JIA, ZHAO JIAN, JINGWEI LI, LIN LUO, LIANG ZHAO, YANG ZHOU, FUQIN TANG & YINGBIN XIAO. (2016) Upregulated ATF6 contributes to chronic intermittent hypoxia-afforded protection against myocardial ischemia/reperfusion injury. International Journal of Molecular Medicine 37:5, pages 1199-1208.
Crossref
Zhen-Guo Ma, Jia Dai, Wen-Bin Zhang, Yuan Yuan, Hai-Han Liao, Ning Zhang, Zhou-Yan Bian & Qi-Zhu Tang. (2016) Protection against cardiac hypertrophy by geniposide involves the GLP-1 receptor / AMPKα signalling pathway. British Journal of Pharmacology 173:9, pages 1502-1516.
Crossref
Mei-qing Liu, Zhe Chen & Lin-xi Chen. (2016) Endoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseases. Acta Pharmacologica Sinica 37:4, pages 425-443.
Crossref
Li Weidong, Li Chunsheng, Zheng Honggang, Chen Guohong & Hua Baojin. (2016) Therapeutic targets of Traditional Chinese Medicine for colorectal cancer. Journal of Traditional Chinese Medicine 36:2, pages 243-249.
Crossref
Rui Liu & Christopher G Proud. (2016) Eukaryotic elongation factor 2 kinase as a drug target in cancer, and in cardiovascular and neurodegenerative diseases. Acta Pharmacologica Sinica 37:3, pages 285-294.
Crossref
Huifang M. Zhang, Fengping Wang, Ye Qiu, Xin Ye, Paul Hanson, Hongxing Shen & Decheng Yang. (2016) Emodin inhibits coxsackievirus B3 replication via multiple signalling cascades leading to suppression of translation. Biochemical Journal 473:4, pages 473-485.
Crossref
Tae Jung & Kyung Choi. (2016) Pharmacological Modulators of Endoplasmic Reticulum Stress in Metabolic Diseases. International Journal of Molecular Sciences 17:2, pages 192.
Crossref
Evangelos P. Daskalopoulos, Cécile Dufeys, Luc Bertrand, Christophe Beauloye & Sandrine Horman. (2016) AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation. Journal of Molecular and Cellular Cardiology 91, pages 188-200.
Crossref
Hirobumi Asai, Junya Hirata, Ayumi Hirano, Kazuya Hirai, Sayaka Seki & Mie Watanabe-Akanuma. (2016) Activation of aryl hydrocarbon receptor mediates suppression of hypoxia-inducible factor-dependent erythropoietin expression by indoxyl sulfate. American Journal of Physiology-Cell Physiology 310:2, pages C142-C150.
Crossref
Victòria Ceperuelo-Mallafré, Miriam Ejarque, Carolina Serena, Xavier Duran, Marta Montori-Grau, Miguel Angel Rodríguez, Oscar Yanes, Catalina Núñez-Roa, Kelly Roche, Prasanth Puthanveetil, Lourdes Garrido-Sánchez, Enrique Saez, Francisco J. Tinahones, Pablo M. Garcia-Roves, Anna Ma Gómez-Foix, Alan R. Saltiel, Joan Vendrell & Sonia Fernández-Veledo. (2016) Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans. Molecular Metabolism 5:1, pages 5-18.
Crossref
Chan Gyu Lee, Ja Hyun Koo & Sang Geon Kim. (2015) Phytochemical regulation of Fyn and AMPK signaling circuitry. Archives of Pharmacal Research 38:12, pages 2093-2105.
Crossref
Luciano Cominacini, Chiara Mozzini, Ulisse Garbin, Andrea Pasini, Chiara Stranieri, Erika Solani, Paola Vallerio, Irene Alessandra Tinelli & Anna Fratta Pasini. (2015) Endoplasmic reticulum stress and Nrf2 signaling in cardiovascular diseases. Free Radical Biology and Medicine 88, pages 233-242.
Crossref
Mounia Guerram, Zhen-Zhou Jiang, Bashir Alsiddig Yousef, Aida Mejda Hamdi, Hozeifa Mohamed Hassan, Zi-Qiao Yuan, Hou-Wei Luo, Xiong Zhu & Lu-Yong Zhang. (2015) The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways. Oncotarget 6:26, pages 21865-21877.
Crossref
Francisco Altamirano, Zhao V. Wang & Joseph A. Hill. (2015) Cardioprotection in ischaemia–reperfusion injury: novel mechanisms and clinical translation. The Journal of Physiology 593:17, pages 3773-3788.
Crossref
Tae Woo Jung, Hwan-Jin Hwang, Ho Cheol Hong, Hye Jin Yoo, Sei Hyun Baik & Kyung Mook Choi. (2015) BAIBA attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice. Diabetologia 58:9, pages 2096-2105.
Crossref
Jiqian Xu, Houxiang Hu, Bin Chen, Rongchuan Yue, Zhou Zhou, Yin Liu, Shuang Zhang, Lei Xu, Huan Wang & Zhengping Yu. (2015) Lycopene Protects against Hypoxia/Reoxygenation Injury by Alleviating ER Stress Induced Apoptosis in Neonatal Mouse Cardiomyocytes. PLOS ONE 10:8, pages e0136443.
Crossref
Wei-Wei Lu, Lei Zhao, Jin-Sheng Zhang, Yue-Long Hou, Yan-Rong Yu, Mo-Zhi Jia, Chao-Shu Tang & Yong-Fen Qi. (2015) Intermedin1–53 protects against cardiac hypertrophy by inhibiting endoplasmic reticulum stress via activating AMP-activated protein kinase. Journal of Hypertension 33:8, pages 1676-1687.
Crossref
Dake Qi & Lawrence H. Young. (2015) AMPK: energy sensor and survival mechanism in the ischemic heart. Trends in Endocrinology & Metabolism 26:8, pages 422-429.
Crossref
Laia Salvadó, Xavier Palomer, Emma Barroso & Manuel Vázquez-Carrera. (2015) Targeting endoplasmic reticulum stress in insulin resistance. Trends in Endocrinology & Metabolism 26:8, pages 438-448.
Crossref
Fanyu Meng, Hua Ning, Zongxiang Sun, Fangfang Huang, Yanchuan Li, Xia Chu, Huimin Lu, Changhao Sun & Songtao Li. (2015) Ursolic acid protects hepatocytes against lipotoxicity through activating autophagy via an AMPK pathway. Journal of Functional Foods 17, pages 172-182.
Crossref
Christopher G. Proud. (2015) Regulation and roles of elongation factor 2 kinase. Biochemical Society Transactions 43:3, pages 328-332.
Crossref
Ling Niu, Xiu-hua He, Qing-wen Wang, Ming-yu Fu, Feng Xu, Ying Xue, Zhen-zhou Wang & Xin-jiang An. (2015) Polyphenols in Regulation of Redox Signaling and Inflammation During Cardiovascular Diseases. Cell Biochemistry and Biophysics 72:2, pages 485-494.
Crossref
Giselle Barreto-Torres, Jessica Soto Hernandez, Sehwan Jang, Adlín R. Rodríguez-Muñoz, Carlos A. Torres-Ramos, Alexei G. Basnakian & Sabzali Javadov. (2015) The beneficial effects of AMP kinase activation against oxidative stress are associated with prevention of PPARα-cyclophilin D interaction in cardiomyocytes. American Journal of Physiology-Heart and Circulatory Physiology 308:7, pages H749-H758.
Crossref
Seong Hun Kim, Kook Hwan Kim, Hyoung-Kyu Kim, Mi-Jeong Kim, Sung Hoon Back, Morichika Konishi, Nobuyuki Itoh & Myung-Shik Lee. (2014) Fibroblast growth factor 21 participates in adaptation to endoplasmic reticulum stress and attenuates obesity-induced hepatic metabolic stress. Diabetologia 58:4, pages 809-818.
Crossref
Lan Yang, Li-yun Zheng, Ye Tian, Zhi-qing Zhang, Wan-li Dong, Xu-fen Wang, Xiao-ying Zhang & Cong Cao. (2015) C6 ceramide dramatically enhances docetaxel-induced growth inhibition and apoptosis in cultured breast cancer cells: A mechanism study. Experimental Cell Research 332:1, pages 47-59.
Crossref
Justin W. Kenney, Oksana Sorokina, Maja Genheden, Anatoly Sorokin, J. Douglas Armstrong & Christopher G. Proud. (2015) Dynamics of Elongation Factor 2 Kinase Regulation in Cortical Neurons in Response to Synaptic Activity. The Journal of Neuroscience 35:7, pages 3034-3047.
Crossref
Hyosang Kim, Soo Young Moon, Joon-Seok Kim, Chung Hee Baek, Miyeon Kim, Ji Yeon Min & Sang Koo Lee. (2015) Activation of AMP-activated protein kinase inhibits ER stress and renal fibrosis. American Journal of Physiology-Renal Physiology 308:3, pages F226-F236.
Crossref
Kwang Min Lee, Seung-Joo Yang, Sojung Park, Yoo Duk Choi, Hwa Kyoung Shin, Jhang Ho Pak, Chul-Seung Park & Inki Kim. (2015) Depletion of the cereblon gene activates the unfolded protein response and protects cells from ER stress-induced cell death. Biochemical and Biophysical Research Communications 458:1, pages 34-39.
Crossref
John R. P. KnightAmandine BastideAnne RoobolJo RoobolThomas J. JacksonWahyu UtamiDavid A. BarrettC. Mark SmalesAnne E. Willis. (2015) Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation. Biochemical Journal 465:2, pages 227-238.
Crossref
Keith E. Latham. 2015. 227 265 .
Martin Pelosse, Malgorzata Tokarska-Schlattner & Uwe Schlattner. 2015. Cardiac Cytoarchitecture. Cardiac Cytoarchitecture 187 225 .
Madeleen Bosma, Dianne H. Dapito, Zoi Drosatos-Tampakaki, Ni Huiping-Son, Li-Shin Huang, Sander Kersten, Konstantinos Drosatos & Ira J. Goldberg. (2014) Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1841:12, pages 1648-1655.
Crossref
Xavier Palomer, Eva Capdevila-Busquets, Gerard Garreta, Mercy M. Davidson & Manuel Vázquez-Carrera. (2014) PPARα atenúa el estrés del retículo endoplasmático inducido por palmitato en células cardíacas humanas por medio de la inducción de la actividad AMPK. Clínica e Investigación en Arteriosclerosis 26:6, pages 255-267.
Crossref
Guang-Zhi Dong, Ju-Hee Lee, Sung Hwan Ki, Ji Hye Yang, Il Je Cho, Seung Ho Kang, Rong Jie Zhao, Sang Chan Kim & Young Woo Kim. (2014) AMPK activation by isorhamnetin protects hepatocytes against oxidative stress and mitochondrial dysfunction. European Journal of Pharmacology 740, pages 634-640.
Crossref
Laia Salvadó, Emma Barroso, Anna Maria Gómez-Foix, Xavier Palomer, Liliane Michalik, Walter Wahli & Manuel Vázquez-Carrera. (2014) PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism. Diabetologia 57:10, pages 2126-2135.
Crossref
Hongliang Li, Qing Min, Changhan Ouyang, Jiyeon Lee, Chaoyong He, Ming-Hui Zou & Zhonglin Xie. (2014) AMPK activation prevents excess nutrient-induced hepatic lipid accumulation by inhibiting mTORC1 signaling and endoplasmic reticulum stress response. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1842:9, pages 1844-1854.
Crossref
Nassrene Y. Elmadhun, Ashraf A. Sabe, Antonio D. Lassaletta & Frank W. Sellke. (2014) Alcohol Consumption Mitigates Apoptosis and Mammalian Target of Rapamycin Signaling in Myocardium. Journal of the American College of Surgeons 218:6, pages 1175-1181.
Crossref
Justin W. Kenney, Claire E. Moore, Xuemin Wang & Christopher G. Proud. (2014) Eukaryotic elongation factor 2 kinase, an unusual enzyme with multiple roles. Advances in Biological Regulation 55, pages 15-27.
Crossref
Botao Liu & Shu-Bing Qian. (2014) Translational reprogramming in cellular stress response. Wiley Interdisciplinary Reviews: RNA 5:3, pages 301-305.
Crossref
Nicola E. ClarkeNikolai D. BelyaevDaniel W. LambertAnthony J. Turner. (2013) Epigenetic regulation of angiotensin-converting enzyme 2 (ACE2) by SIRT1 under conditions of cell energy stress. Clinical Science 126:7, pages 507-516.
Crossref
Ching-Yi Weng, Shu-Yuan Chiou, Lisu Wang, Mei-Chun Kou, Ying-Jan Wang & Ming-Jiuan Wu. (2013) Arsenic trioxide induces unfolded protein response in vascular endothelial cells. Archives of Toxicology 88:2, pages 213-226.
Crossref
Volker UllrichStefan Schildknecht. (2014) Sensing Hypoxia by Mitochondria: A Unifying Hypothesis Involving S-Nitrosation. Antioxidants & Redox Signaling 20:2, pages 325-338.
Crossref
Yu-Chin Lin, Meng-Hsuan WuTzu-Tang WeiYun-Chieh LinWen-Chih HuangLiang-Yu HuangYi-Ting LinChing-Chow Chen. (2014) Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress. Oncotarget 5:1, pages 298-308.
Crossref
Dmitry A. Chistiakov, Igor A. Sobenin, Alexander N. Orekhov & Yuri V. Bobryshev. (2014) Role of Endoplasmic Reticulum Stress in Atherosclerosis and Diabetic Macrovascular Complications. BioMed Research International 2014, pages 1-14.
Crossref
Tae Woo Jung, So Young Lee, Ho Cheol Hong, Hae Yoon Choi, Hye Jin Yoo, Sei Hyun Baik & Kyung Mook Choi. (2014) AMPK activator-mediated inhibition of endoplasmic reticulum stress ameliorates carrageenan-induced insulin resistance through the suppression of selenoprotein P in HepG2 hepatocytes. Molecular and Cellular Endocrinology 382:1, pages 66-73.
Crossref
Guido R. Y. De Meyer, Dorien M. Schrijvers & Wim Martinet. 2014. Aging and Heart Failure. Aging and Heart Failure 339 349 .
Ke-ran Li, Zhi-qing Zhang, Jin Yao, Yu-xia Zhao, Jing Duan, Cong Cao & Qin Jiang. (2013) Ginsenoside Rg-1 Protects Retinal Pigment Epithelium (RPE) Cells from Cobalt Chloride (CoCl2) and Hypoxia Assaults. PLoS ONE 8:12, pages e84171.
Crossref
Guang-Zhi Dong, Eun Jeong Jang, Seung Ho Kang, Il Je Cho, Sun-Dong Park, Sang Chan Kim & Young Woo Kim. (2013) Red ginseng abrogates oxidative stress via mitochondria protection mediated by LKB1-AMPK pathway. BMC Complementary and Alternative Medicine 13:1.
Crossref
Wilfred Lieberthal, Meiyi Tang, Leiqing Zhang, Benoit Viollet, Vimal Patel & Jerrold S Levine. (2013) Susceptibility to ATP depletion of primary proximal tubular cell cultures derived from mice lacking either the α1 or the α2 isoform of the catalytic domain of AMPK. BMC Nephrology 14:1.
Crossref
Cornelius Lehane, Timo Guelzow, Simone Zenker, Anika Erxleben, Christian I. Schwer, Bernd Heimrich, Hartmut Buerkle & Matjaz Humar. (2013) Carbimazole Is an Inhibitor of Protein Synthesis and Protects from Neuronal Hypoxic Damage In Vitro. Journal of Pharmacology and Experimental Therapeutics 347:3, pages 781-793.
Crossref
Xin-Yuan Zhu, Zi-Long Zhang, Pei Li, Wen-Yi Liang, Xue-Ru Feng & Mei-Lin Liu. (2013) Shenyuan, an extract of American Ginseng and Corydalis Tuber formula, attenuates cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and oxidative stress in a porcine model of acute myocardial infarction. Journal of Ethnopharmacology 150:2, pages 672-681.
Crossref
Christian I. Schwer, Cornelius Lehane, Timo Guelzow, Simone Zenker, Karl M. Strosing, Sashko Spassov, Anika Erxleben, Bernd Heimrich, Hartmut Buerkle & Matjaz Humar. (2013) Thiopental Inhibits Global Protein Synthesis by Repression of Eukaryotic Elongation Factor 2 and Protects from Hypoxic Neuronal Cell Death. PLoS ONE 8:10, pages e77258.
Crossref
Kiwon BanBrian WileSangsung KimHun-Jun ParkJaemin ByunKyu-Won ChoTalib SaafirMing-Ke SongShan Ping YuMary WagnerGang BaoYoung-Sup Yoon. (2013) Purification of Cardiomyocytes From Differentiating Pluripotent Stem Cells Using Molecular Beacons That Target Cardiomyocyte-Specific mRNA. Circulation 128:17, pages 1897-1909.
Crossref
Ying-Chun Chen, Xiao-Yi Zeng, Yan He, Hong Liu, Bin Wang, Han Zhou, Jian-Wen Chen, Pei-Qing Liu, Lian-Quan Gu, Ji-Ming Ye & Zhi-Shu Huang. (2013) Rutaecarpine Analogues Reduce Lipid Accumulation in Adipocytes via Inhibiting Adipogenesis/Lipogenesis with AMPK Activation and UPR Suppression . ACS Chemical Biology 8:10, pages 2301-2311.
Crossref
Gai-Gai Zhang, Huai-Qiu Cai, Yan-Hui Li, Yu-Bin Sui, Jin-Sheng Zhang, Jin-Rui Chang, Ming Ning, Yang Wu, Chao-Shu Tang, Yong-Fen Qi & Xin-Hua Yin. (2013) Ghrelin protects heart against ERS-induced injury and apoptosis by activating AMP-activated protein kinase. Peptides 48, pages 156-165.
Crossref
Min-Bin Chen, Yan Zhang, Mu-Xin Wei, Wei Shen, Xiao-Yang Wu, Chen Yao & Pei-Hua Lu. (2013) Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells. Cellular Signalling 25:10, pages 1993-2002.
Crossref
Francesco Onorati, Carol Chen-Scarabelli, Richard Knight, Anastasis Stephanou, Bibhu Mohanti, Francesco Santini, Maddalena Tessari, Annapoorna Kini, Jagat Narula, Louis Saravolatz, Alessandro Mazzucco, Tiziano Scarabelli & Giuseppe Faggian. (2013) Targeting Urocortin Signaling Pathways to Enhance Cardioprotection: Is It Time to Move from Bench to Bedside?. Cardiovascular Drugs and Therapy 27:5, pages 451-463.
Crossref
Hong Li, Tong Liu, Wei Chen, Mohit Raja Jain, Dorothy E. Vatner, Stephen F. Vatner, Raymond K. Kudej & Lin Yan. (2013) Proteomic Mechanisms of Cardioprotection during Mammalian Hibernation in Woodchucks, Marmota Monax . Journal of Proteome Research 12:9, pages 4221-4229.
Crossref
Gilles M. Leclerc, Guy J. Leclerc, Jeffim N. Kuznetsov, Joanna DeSalvo & Julio C. Barredo. (2013) Metformin Induces Apoptosis through AMPK-Dependent Inhibition of UPR Signaling in ALL Lymphoblasts. PLoS ONE 8:8, pages e74420.
Crossref
Mohamed Amine Zaouali, Eleonora Boncompagni, Russel J. Reiter, Mohamed Bejaoui, Isabel Freitas, Eirini Pantazi, Emma Folch-Puy, Hassen ben Abdennebi, Francisco A. Garcia-Gil & Joan Roselló-Catafau. (2013) AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail. Journal of Pineal Research 55:1, pages 65-78.
Crossref
J. Misra, D.-K. Kim, W. Choi, S.-H. Koo, C.-H. Lee, S.-H. Back, R. J. Kaufman & H.-S. Choi. (2013) Transcriptional cross talk between orphan nuclear receptor ERR  and transmembrane transcription factor ATF6  coordinates endoplasmic reticulum stress response. Nucleic Acids Research 41:14, pages 6960-6974.
Crossref
Yuguang Zhao, Yi Tan, Shugang Xi, Yunqian Li, Cai Li, Jiuwei Cui, Xiaoqing Yan, Xiaokun Li, Guanjun Wang, Wei Li & Lu Cai. (2013) A Novel Mechanism by Which SDF-1β Protects Cardiac Cells From Palmitate-Induced Endoplasmic Reticulum Stress and Apoptosis via CXCR7 and AMPK/p38 MAPK-Mediated Interleukin-6 Generation. Diabetes 62:7, pages 2545-2558.
Crossref
L. Salvadó, T. Coll, A. M. Gómez-Foix, E. Salmerón, E. Barroso, X. Palomer & M. Vázquez-Carrera. (2013) Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism. Diabetologia 56:6, pages 1372-1382.
Crossref
Subat Turdi, Nan Hu & Jun Ren. (2013) Tauroursodeoxycholic Acid Mitigates High Fat Diet-Induced Cardiomyocyte Contractile and Intracellular Ca2+ Anomalies. PLoS ONE 8:5, pages e63615.
Crossref
Liu Yang, Haibo Sha, Robin L. Davisson & Ling Qi. (2013) Phenformin Activates the Unfolded Protein Response in an AMP-activated Protein Kinase (AMPK)-dependent Manner. Journal of Biological Chemistry 288:19, pages 13631-13638.
Crossref
Christina Drevinge, Lars O. Karlsson, Marcus Ståhlman, Thomas Larsson, Jeanna Perman Sundelin, Lars Grip, Linda Andersson, Jan Borén & Malin C. Levin. (2013) Cholesteryl Esters Accumulate in the Heart in a Porcine Model of Ischemia and Reperfusion. PLoS ONE 8:4, pages e61942.
Crossref
Yasunori ShintaniAmar KapoorMasahiro KanekoRyszard T. Smolenski, Fulvio D’AcquistoSteven R. CoppenNarumi Harada-ShojiHack Jae LeeChristoph ThiemermannSeiji Takashima, Kenta YashiroKen Suzuki. (2013) TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons. Proceedings of the National Academy of Sciences 110:13, pages 5109-5114.
Crossref
Kai Chen, Satoru Kobayashi, Xianmin Xu, Benoit Viollet & Qiangrong Liang. (2013) AMP Activated Protein Kinase Is Indispensable for Myocardial Adaptation to Caloric Restriction in Mice. PLoS ONE 8:3, pages e59682.
Crossref
Bin LiangShuangxi WangQilong WangWencheng ZhangBenoit ViolletYi ZhuMing-Hui Zou. (2013) Aberrant Endoplasmic Reticulum Stress in Vascular Smooth Muscle Increases Vascular Contractility and Blood Pressure in Mice Deficient of AMP-Activated Protein Kinase-α2 In Vivo. Arteriosclerosis, Thrombosis, and Vascular Biology 33:3, pages 595-604.
Crossref
Shirin Doroudgar & Christopher C. Glembotski. (2013) New concepts of endoplasmic reticulum function in the heart: Programmed to conserve. Journal of Molecular and Cellular Cardiology 55, pages 85-91.
Crossref
Susana M. Campos, Richard T. Penson, Ursula Matulonis, Neil S. Horowitz, Christin Whalen, Lauren Pereira, Karin Tyburski, Maria Roche, Jackie Szymonifka & Suzanne Berlin. (2013) A phase II trial of Sunitinib malate in recurrent and refractory ovarian, fallopian tube and peritoneal carcinoma. Gynecologic Oncology 128:2, pages 215-220.
Crossref
Tatsuya Usui, Muneyoshi Okada, Yukio Hara & Hideyuki Yamawaki. (2013) Vascular effects of novel calmodulin-related proteins that mediate development of hypertension. Folia Pharmacologica Japonica 141:2, pages 85-89.
Crossref
Hyou-Ju Jin & Chun-Guang Li. (2013) Tanshinone IIA and Cryptotanshinone Prevent Mitochondrial Dysfunction in Hypoxia-Induced H9c2 Cells: Association to Mitochondrial ROS, Intracellular Nitric Oxide, and Calcium Levels. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-11.
Crossref
Oktay Tacar, Pornsak Sriamornsak & Crispin R Dass. (2013) Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. Journal of Pharmacy and Pharmacology 65:2, pages 157-170.
Crossref
Liu Chun-Lei, Li Xin, Hu Guo-Liang, Li Rui-Jun, He Yun-Yun, Zhong Wu, Li Song, He Kun-Lun & Wang Li-Li. (2012) Salubrinal protects against tunicamycin and hypoxia induced cardiomyocyte apoptosis via the PERK-eIF2α signaling pathwaySalubrinal protects against tunicamycin and hypoxia induced cardiomyocyte apoptosis via the PERK-eIF2α signaling pathway. Journal of Geriatric Cardiology 9:3, pages 258-268.
Crossref
Jun Lu, Qinghua Wang, Lianghu Huang, Huiyue Dong, Lingjing Lin, Na Lin, Feng Zheng & Jianming Tan. (2012) Palmitate Causes Endoplasmic Reticulum Stress and Apoptosis in Human Mesenchymal Stem Cells: Prevention by AMPK Activator. Endocrinology 153:11, pages 5275-5284.
Crossref
Juquan Song, Celeste C. Finnerty, David N. Herndon, Robert Kraft, Darren Boehning, Natasha C. Brooks, Ronald G. Tompkins & Marc G. Jeschke. (2012) Thermal Injury Activates the eEF2K-Dependent eEF2 Pathway in Pediatric Patients. Journal of Parenteral and Enteral Nutrition 36:5, pages 596-602.
Crossref
Maria GalánModar KassanSoo-Kyoung ChoiMegan PartykaMohamed TrebakDaniel HenrionKhalid Matrougui. (2012) A Novel Role for Epidermal Growth Factor Receptor Tyrosine Kinase and Its Downstream Endoplasmic Reticulum Stress in Cardiac Damage and Microvascular Dysfunction in Type 1 Diabetes Mellitus. Hypertension 60:1, pages 71-80.
Crossref
Modar KassanMaria GalánMegan PartykaZubaida SaifudeenDaniel HenrionMohamed TrebakKhalid Matrougui. (2012) Endoplasmic Reticulum Stress Is Involved in Cardiac Damage and Vascular Endothelial Dysfunction in Hypertensive Mice. Arteriosclerosis, Thrombosis, and Vascular Biology 32:7, pages 1652-1661.
Crossref
Ja Hyun Koo, Woo Hyung Lee, Chan Gyu Lee & Sang Geon Kim. (2012) Fyn Inhibition by Cycloalkane-Fused 1,2-Dithiole-3-thiones Enhances Antioxidant Capacity and Protects Mitochondria from Oxidative Injury. Molecular Pharmacology 82:1, pages 27-36.
Crossref
Yuan Gu, Xiao-xiao Sun, Ji-ming Ye, Li He, Shou-sheng Yan, Hao-hao Zhang, Li-hong Hu, Jun-ying Yuan & Qiang Yu. (2012) Arctigenin alleviates ER stress via activating AMPK. Acta Pharmacologica Sinica 33:7, pages 941-952.
Crossref
Kathryn J. Huber-Keener, Brad R. Evans, Xingcong Ren, Yan Cheng, Yi Zhang, William N. Hait & Jin-Ming Yang. (2012) Phosphorylation of elongation factor-2 kinase differentially regulates the enzyme’s stability under stress conditions. Biochemical and Biophysical Research Communications 424:2, pages 308-314.
Crossref
Yingli Wang, Bo Wan, Dawei Li, Jun Zhou, Ruwei Li, Meirong Bai, Fang Chen & Long Yu. (2012) BRSK2 is regulated by ER stress in protein level and involved in ER stress-induced apoptosis. Biochemical and Biophysical Research Communications 423:4, pages 813-818.
Crossref
Jun-jie Shao, Ai-ping Zhang, Wei Qin, Lin Zheng, Yi-fan Zhu & Xin Chen. (2012) AMP-activated protein kinase (AMPK) activation is involved in chrysin-induced growth inhibition and apoptosis in cultured A549 lung cancer cells. Biochemical and Biophysical Research Communications 423:3, pages 448-453.
Crossref
Masaya Tanno, Atsushi Kuno, Yoshiyuki Horio & Tetsuji Miura. (2012) Emerging beneficial roles of sirtuins in heart failure. Basic Research in Cardiology 107:4.
Crossref
Lianru Zhang, Yuting Yi, Qiuju Guo, Yifei Sun, Shun Ma, Shuyan Xiao, Jing Geng, Zhonghui Zheng & Siyang Song. (2012) Hsp90 interacts with AMPK and mediates acetyl-CoA carboxylase phosphorylation. Cellular Signalling 24:4, pages 859-865.
Crossref
Thomas Quentin, Michael Steinmetz, Andrea Poppe & Sven Thoms. (2012) Metformin differentially activates ER stress signaling pathways without inducing apoptosis. Disease Models & Mechanisms 5:2, pages 259-269.
Crossref
Qing-you Zheng, Feng-suo Jin, Chen Yao, Tong Zhang, Guo-hui Zhang & Xing Ai. (2012) Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells. Biochemical and Biophysical Research Communications 419:4, pages 741-747.
Crossref
Chen Wang, Yu-Zhen Li, Xiao-Reng Wang, Zhen-Rong Lu, Da-Zhuo Shi & Xiu-Hua Liu. (2012) Panax quinquefolium Saponins Reduce Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Excessive Endoplasmic Reticulum Stress. Shock 37:2, pages 228-233.
Crossref
S.F. Williams, E. Fik, S. Zamudio & N.P. Illsley. (2012) Global protein synthesis in human trophoblast is resistant to inhibition by hypoxia. Placenta 33:1, pages 31-38.
Crossref
Theodore Kalogeris, Christopher P. Baines, Maike Krenz & Ronald J. Korthuis. 2012. International Review of Cell and Molecular Biology Volume 298. International Review of Cell and Molecular Biology Volume 298 229 317 .
Xuejun Wang & Cam Patterson. 2012. Muscle. Muscle 353 367 .
Jian Cao, Komal Sodhi, Nitin Puri, Sumit R Monu, Rita Rezzani & Nader G Abraham. (2011) High fat diet enhances cardiac abnormalities in SHR rats: Protective role of heme oxygenase-adiponectin axis. Diabetology & Metabolic Syndrome 3:1.
Crossref
Wilfred Lieberthal, Leiqing Zhang, Vimal A. Patel & Jerrold S. Levine. (2011) AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation. American Journal of Physiology-Renal Physiology 301:6, pages F1177-F1192.
Crossref
Colin F. Greineder, Sarah Kohnstamm & Bonnie Ky. (2011) Heart Failure Associated with Sunitinib: Lessons Learned from Animal Models. Current Hypertension Reports 13:6, pages 436-441.
Crossref
J.D. Cohen, J.E. Babiarz, R.M. Abrams, L. Guo, S. Kameoka, E. Chiao, J. Taunton & K.L. Kolaja. (2011) Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations. Toxicology and Applied Pharmacology 257:1, pages 74-83.
Crossref
Agnese Viganò, Michele Vasso, Anna Caretti, Valentina Bravatà, Laura Terraneo, Chiara Fania, Daniele Capitanio, Michele Samaja & Cecilia Gelfi. (2011) Protein modulation in mouse heart under acute and chronic hypoxia. PROTEOMICS 11:21, pages 4202-4217.
Crossref
Jianping Tao, Wei Zhu, Yapeng Li, Ping Xin, Jing Li, Mingya Liu, Jingbo Li, Andrew N. Redington & Meng Wei. (2011) Apelin-13 protects the heart against ischemia-reperfusion injury through inhibition of ER-dependent apoptotic pathways in a time-dependent fashion. American Journal of Physiology-Heart and Circulatory Physiology 301:4, pages H1471-H1486.
Crossref
Juhae Kim, Youn-Jin Park, Yumi Jang & Young Hye Kwon. (2011) AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells. Brain Research 1418, pages 42-51.
Crossref

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