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Chromosome Structure and Dynamics

Identification, Characterization, and Cell Specificity of a Human LINE-1 Promoter

Pages 6718-6729 | Received 02 Jul 1990, Accepted 13 Sep 1990, Published online: 31 Mar 2023

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Loredana Frassinelli, Elisa Orecchini, Sofian Al-Wardat, Marco Tripodi, Carmine Mancone, Margherita Doria, Silvia Galardi, Silvia Anna Ciafrè & Alessandro Michienzi. (2021) The RNA editing enzyme ADAR2 restricts L1 mobility. RNA Biology 18:sup1, pages 75-87.
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Juan Du & Ke Zhao. (2021) HIV suppressors against LINE-1: one functions as two. Critical Reviews in Biochemistry and Molecular Biology 56:3, pages 205-220.
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Elisa Orecchini, Loredana Frassinelli & Alessandro Michienzi. (2017) Restricting retrotransposons: ADAR1 is another guardian of the human genome. RNA Biology 14:11, pages 1485-1491.
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Natasha Vafadar-Isfahani, Christina Parr, Lara E. McMillan, Juliane Sanner, Zhao Yeo, Stephen Saddington, Oliver Peacock, Hazel A. Cruickshanks, Richard R. Meehan, Jonathan N. Lund & Cristina Tufarelli. (2017) Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer. Epigenetics 12:6, pages 465-475.
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Jie-Ting Tang, Zhen-Hua Wang & Jing-Yuan Fang. (2015) Assessing the potential value of long interspersed element-1 hypomethylation in colorectal cancer: evidence from retrospective studies. OncoTargets and Therapy 8, pages 3265-3276.
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S Zucchelli, D Cotella, H Takahashi, C Carrieri, L Cimatti, F Fasolo, MH Jones, D Sblattero, R Sanges, C Santoro, F Persichetti, P Carninci & S Gustincich. (2015) SINEUPs: A new class of natural and synthetic antisense long non-coding RNAs that activate translation. RNA Biology 12:8, pages 771-779.
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Sara R Heras, Sara Macias, Javier F Cáceres & Jose L Garcia-Perez. (2014) Control of mammalian retrotransposons by cellular RNA processing activities. Mobile Genetic Elements 4:2.
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Jingchen Jiang, Liuya Zhao, Lan Yan, Lulu Zhang, Yingying Cao, Yan Wang, Yuanying Jiang, Tianhua Yan & Yongbing Cao. (2014) Structural features and mechanism of translocation of non-LTR retrotransposons in Candida albicans. Virulence 5:2, pages 245-252.
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Dustin C. Hancks, Prabhat K. Mandal, Ling E. Cheung & Haig H. Kazazian$suffix/text()$suffix/text(). (2012) The Minimal Active Human SVA Retrotransposon Requires Only the 5′-Hexamer and Alu-Like Domains. Molecular and Cellular Biology 32:22, pages 4718-4726.
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Kristel Kaer & Mart Speek. (2012) Intronic retroelements. Mobile Genetic Elements 2:3, pages 154-157.
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Francisco Sánchez-Luque, Manuel C. López, Francisco Macias, Carlos Alonso & M. Carmen Thomas. (2012) Pr77 and L1TcRz. Mobile Genetic Elements 2:1, pages 1-7.
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Kyle R. Upton, J. Kenneth Baillie & Geoffrey J. Faulkner. (2011) Is somatic retrotransposition a parasitic or symbiotic phenomenon?. Mobile Genetic Elements 1:4, pages 279-328.
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Martin Muñoz-Lopez, Angela Macia, Marta Garcia-Cañadas, Richard M. Badge & Jose L. Garcia-Perez. (2011) An epi [c] genetic battle. Mobile Genetic Elements 1:2, pages 122-127.
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Angela Macia, Martin Muñoz-Lopez, Jose Luis Cortes, Robert K. Hastings, Santiago Morell, Gema Lucena-Aguilar, Juan Antonio Marchal, Richard M. Badge & Jose Luis Garcia-Perez. (2011) Epigenetic Control of Retrotransposon Expression in Human Embryonic Stem Cells. Molecular and Cellular Biology 31:2, pages 300-316.
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Danna G. Eickbush & Thomas H. Eickbush. (2010) R2 Retrotransposons Encode a Self-Cleaving Ribozyme for Processing from an rRNA Cotranscript. Molecular and Cellular Biology 30:13, pages 3142-3150.
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Sergey E. Dmitriev, Dmitri E. Andreev, Ilya M. Terenin, Ivan A. Olovnikov, Vladimir S. Prassolov, William C. Merrick & Ivan N. Shatsky. (2007) Efficient Translation Initiation Directed by the 900-Nucleotide-Long and GC-Rich 5′ Untranslated Region of the Human Retrotransposon LINE-1 mRNA Is Strictly Cap Dependent Rather than Internal Ribosome Entry Site Mediated. Molecular and Cellular Biology 27:13, pages 4685-4697.
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Mart Speek. (2001) Antisense Promoter of Human L1 Retrotransposon Drives Transcription of Adjacent Cellular Genes. Molecular and Cellular Biology 21:6, pages 1973-1985.
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Wei Wei, Nicolas Gilbert, Siew Loon Ooi, Joseph F. Lawler, Eric M. Ostertag, Haig H. Kazazian, Jef D. Boeke & John V. Moran. (2001) Human L1 Retrotransposition: cisPreference versus trans Complementation. Molecular and Cellular Biology 21:4, pages 1429-1439.
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Kazuhiko Ohshima, Mitsuhiro Hamada, Yohey Terai & Norihiro Okada. (1996) The 3′ Ends of tRNA-Derived Short Interspersed Repetitive Elements Are Derived from the 3′ Ends of Long Interspersed Repetitive Elements. Molecular and Cellular Biology 16:7, pages 3756-3764.
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Gerald Schumann, Ilse Zündorf, Jörg Hofmann, Rolf Marschalek & Theodor Dingermann. (1994) Internally Located and Oppositely Oriented Polymerase II Promoters Direct Convergent Transcription of a LINE-Like Retroelement, the Dictyostelium Repetitive Element, from Dictyostelium discoideum. Molecular and Cellular Biology 14:5, pages 3074-3084.
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Nora J. Besansky, Susan M. Paskewitz, Diane Mills Hamm & Frank H. Collins. (1992) Distinct Families of Site-Specific Retrotransposons Occupy Identical Positions in the rRNA Genes of Anopheles gambiae. Molecular and Cellular Biology 12:11, pages 5102-5110.
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Heini Ilves, Olev Kahre & Mart Speek. (1992) Translation of the Rat LINE Bicistronic RNAs In Vitro Involves Ribosomal Reinitiation instead of Frameshifting. Molecular and Cellular Biology 12:9, pages 4242-4248.
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Gabriella Minchiotti & Pier Paolo Di Nocera. (1991) Convergent Transcription Initiates from Oppositely Oriented Promoters within the 5′ End Regions of Drosophila melanogaster F Elements. Molecular and Cellular Biology 11:10, pages 5171-5180.
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Articles from other publishers (13)

Srinjoy Sil, Sarah Keegan, Farida Ettefa, Lance T Denes, Jef D Boeke & Liam J Holt. (2023) Condensation of LINE-1 is critical for retrotransposition. eLife 12.
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Ji-Hoon Son, Hyunsu Do & Jinju Han. (2022) Intragenic L1 Insertion: One Possibility of Brain Disorder. Life 12:9, pages 1425.
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Doris Loh & Russel J. Reiter. (2022) Melatonin: Regulation of Viral Phase Separation and Epitranscriptomics in Post-Acute Sequelae of COVID-19. International Journal of Molecular Sciences 23:15, pages 8122.
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Yifei Zhao, Juan Du, Yu Wang, Qing Wang, Shaohua Wang & Ke Zhao. (2022) BST2 Suppresses LINE-1 Retrotransposition by Reducing the Promoter Activity of LINE-1 5′ UTR. Journal of Virology 96:2.
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Ahmad Luqman-Fatah & Tomoichiro Miyoshi. (2022) Human LINE-1 retrotransposons: impacts on the genome and regulation by host factors. Genes & Genetic Systems.
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John B. MoldovanYifan WangStewart Shuman, Ryan E. Mills & John V. Moran. (2019) RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA. Proceedings of the National Academy of Sciences 116:41, pages 20612-20622.
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Xiaoji SunXuya WangZuojian TangMark GrivainisDavid Kahler, Chi Yun, Paolo MitaDavid FenyöJef D. Boeke. (2018) Transcription factor profiling reveals molecular choreography and key regulators of human retrotransposon expression. Proceedings of the National Academy of Sciences 115:24.
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Sandra R. Richardson, Aurélien J. Doucet, Huira C. Kopera, John B. Moldovan, José Luis Garcia-Perez & John V. Moran. (2015) The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes. Microbiology Spectrum 3:2.
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Huira C. KoperaJohn B. Moldovan, Tammy A. MorrishJose Luis Garcia-PerezJohn V. Moran. (2011) Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase. Proceedings of the National Academy of Sciences 108:51, pages 20345-20350.
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Shuji KuboMaria del Carmen SelemeHarris S. Soifer, José Luis Garcia Perez, John V. Moran, Haig H. KazazianJr.Jr. & Noriyuki Kasahara. (2006) L1 retrotransposition in nondividing and primary human somatic cells. Proceedings of the National Academy of Sciences 103:21, pages 8036-8041.
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Maria del Carmen SelemeMelissa R. VetterRichard Cordaux, Laurel Bastone, Mark A. Batzer & Haig H. KazazianJr.Jr.. (2006) Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity. Proceedings of the National Academy of Sciences 103:17, pages 6611-6616.
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Brook Brouha, Joshua Schustak, Richard M. Badge, Sheila Lutz-Prigge, Alexander H. Farley, John V. Moran & Haig H. KazazianJr.Jr.. (2003) Hot L1s account for the bulk of retrotransposition in the human population. Proceedings of the National Academy of Sciences 100:9, pages 5280-5285.
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Michael Knössl, Roswitha Löwer & Johannes Löwer. (1999) Expression of the Human Endogenous Retrovirus HTDV/HERV-K Is Enhanced by Cellular Transcription Factor YY1. Journal of Virology 73:2, pages 1254-1261.
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