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Cell Growth and Development

Point Mutations in the abl SH2 Domain Coordinately Impair Phosphotyrosine Binding In Vitro and Transforming Activity In Vivo

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Pages 609-618 | Received 29 Jul 1991, Accepted 13 Nov 1991, Published online: 01 Apr 2023

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Myeong Gu Yeo, Michael A. Partridge, Ellen J. Ezratty, Qiong Shen, Gregg G. Gundersen & Eugene E. Marcantonio. (2006) Src SH2 Arginine 175 Is Required for Cell Motility: Specific Focal Adhesion Kinase Targeting and Focal Adhesion Assembly Function. Molecular and Cellular Biology 26:12, pages 4399-4409.
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Shu-yue Ren, Elisabeth Bolton, M. Golam Mohi, Andrea Morrione, Benjamin G. Neel & Tomasz Skorski. (2005) Phosphatidylinositol 3-Kinase p85α Subunit-Dependent Interaction with BCR/ABL-Related Fusion Tyrosine Kinases: Molecular Mechanisms and Biological Consequences. Molecular and Cellular Biology 25:18, pages 8001-8008.
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Brenda J. Irvin, Brandi L. Williams, Allan E. Nilson, Hannah O. Maynor & Robert T. Abraham. (2000) Pleiotropic Contributions of Phospholipase C-γ1 (PLC-γ1) to T-Cell Antigen Receptor-Mediated Signaling: Reconstitution Studies of a PLC-γ1-Deficient Jurkat T-Cell Line. Molecular and Cellular Biology 20:24, pages 9149-9161.
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Qun-sheng Ji, Ansuman Chattopadhyay, Manuela Vecchi & Graham Carpenter. (1999) Physiological Requirement for Both SH2 Domains for Phospholipase C-γ1 Function and Interaction with Platelet-Derived Growth Factor Receptors. Molecular and Cellular Biology 19:7, pages 4961-4970.
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Nika N. Danial, Julie A. Losman, Tianhong Lu, Natalie Yip, Kartik Krishnan, John Krolewski, Stephen P. Goff, Jean Y. J. Wang & Paul B. Rothman. (1998) Direct Interaction of Jak1 and v-Abl Is Required for v-Abl-Induced Activation of STATs and Proliferation. Molecular and Cellular Biology 18:11, pages 6795-6804.
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Huaiyuan Jiao, Karim Berrada, Wentian Yang, Mina Tabrizi, Leonidas C. Platanias & Taolin Yi. (1996) Direct Association with and Dephosphorylation of Jak2 Kinase by the SH2-Domain-Containing Protein Tyrosine Phosphatase SHP-1. Molecular and Cellular Biology 16:12, pages 6985-6992.
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Masamitsu Tanaka, Ruchika Gupta & Bruce J. Mayer. (1995) Differential Inhibition of Signaling Pathways by Dominant-Negative SH2/SH3 Adapter Proteins. Molecular and Cellular Biology 15:12, pages 6829-6837.
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Lily Shiue, J. Green, O. M. Green, Jennifer L. Karas, Jay P. Morgenstern, Mary K. Ram, Marta K. Taylor, Mark J. Zoller, Lynne D. Zydowsky, Joseph B. Bolen & Joan S. Brugge. (1995) Interaction of p72 with the γ and β Subunits of the High-Affinity Receptor for Immunoglobulin E, FcεRI. Molecular and Cellular Biology 15:1, pages 272-281.
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Govindaswamy Panchamoorthy, Toru Fukazawa, Lesley Stolz, Gillian Payne, Kris Reedquist, Steven Shoelson, Zhou Songyang, Lewis Cantley, Christopher Walsh & Hamid Band. (1994) Physical and Functional Interactions between SH2 and SH3 Domains of the Src Family Protein Tyrosine Kinase p59. Molecular and Cellular Biology 14:9, pages 6372-6385.
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Monique Yoakim, Weimin Hou, Zhou Songyang, Yuxi Liu, Lewis Cantley & Brian Schaffhausen. (1994) Genetic Analysis of a Phosphatidylinositol 3-Kinase SH2 Domain Reveals Determinants of Specificity. Molecular and Cellular Biology 14:9, pages 5929-5938.
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Brian W. Howell & Jonathan A. Cooper. (1994) Csk Suppression of Src Involves Movement of Csk to Sites of Src Activity. Molecular and Cellular Biology 14:8, pages 5402-5411.
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Bruce J. Mayer & David Baltimore. (1994) Mutagenic Analysis of the Roles of SH2 and SH3 Domains in Regulation of the Abl Tyrosine Kinase. Molecular and Cellular Biology 14:5, pages 2883-2894.
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Dwaine D. Wright, Bartholomew M. Sefton & Mark P. Kamps. (1994) Oncogenic Activation of the Lck Protein Accompanies Translocation of the LCK Gene in the Human HSB2 T-Cell Leukemia. Molecular and Cellular Biology 14:4, pages 2429-2437.
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Taolin Yi, Alice L.-F. Mui, Gerald Krystal & James N. Ihle. (1993) Hematopoietic Cell Phosphatase Associates with the Interleukin-3 (IL-3) Receptor β Chain and Down-Regulates IL-3-Induced Tyrosine Phosphorylation and Mitogenesis. Molecular and Cellular Biology 13:12, pages 7577-7586.
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Christine Hall, Wun Chey Sin, Mabel Teo, Gregory J. Michael, Paul Smith, Jing Ming Dong, Hong Hwa Lim, Edward Manser, Nigel K. Spurr, Tania A. Jones & Louis Lim. (1993) α2-Chimerin, an SH2-Containing GTPase-Activating Protein for the ras-Related Protein p21rac Derived by Alternate Splicing of the Human n-Chimerin Gene, Is Selectively Expressed in Brain Regions and Testes. Molecular and Cellular Biology 13:8, pages 4986-4998.
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G. Panayotou, G. Gish, P. End, O. Truong, I. Gout, R. Dhand, M. J. Fry, I. Hiles, T. Pawson & M. D. Waterfield. (1993) Interactions Between SH2 Domains and Tyrosine-Phosphorylated Platelet-Derived Growth Factor β-receptor Sequences: Analysis of Kinetic Parameters by a Novel Biosensor-Based Approach. Molecular and Cellular Biology 13:6, pages 3567-3576.
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Alexander J. Muller, Ann-Marie Pendergast, Marie H. Havlik, Lorri Puil, Tony Pawson & Owen N. Witte1. (1992) A Limited Set of SH2 Domains Binds BCR through a High- Affinity Phosphotyrosine-Independent Interaction. Molecular and Cellular Biology 12:11, pages 5087-5093.
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Kunxin Luo & Bartholomew M. Sefton. (1992) Activated lek Tyrosine Protein Kinase Stimulates AntigenIndependent Interleukin-2 Production in T Cells. Molecular and Cellular Biology 12:10, pages 4724-4732.
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Chae-Ryun Yi & Naomi Rosenberg. (2007) Gag Influences Transformation by Abelson Murine Leukemia Virus and Suppresses Nuclear Localization of the v-Abl Protein. Journal of Virology 81:17, pages 9461-9468.
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Linda B. Baughn & Naomi Rosenberg. (2005) Disruption of the Shc/Grb2 Complex during Abelson Virus Transformation Affects Proliferation, but Not Apoptosis. Journal of Virology 79:4, pages 2325-2334.
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Richard A Van Etten. (2002) Studying the pathogenesis of BCR–ABL+ leukemia in mice. Oncogene 21:56, pages 8643-8651.
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Ralph B Arlinghaus. (2002) Bcr: a negative regulator of the Bcr-Abl oncoprotein in leukemia. Oncogene 21:56, pages 8560-8567.
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Bernard A Callus & Bernard Mathey-Prevot. (2002) SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc. Oncogene 21:31, pages 4812-4821.
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Bradley B Brasher, Sergei Roumiantsev & Richard A Van Etten. (2001) Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain. Oncogene 20:53, pages 7744-7752.
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Liang Feng & Kevin A W Lee. (2001) A repetitive element containing a critical tyrosine residue is required for transcriptional activation by the EWS/ATF1 oncogene. Oncogene 20:31, pages 4161-4168.
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Celine A. Mainville, Kalindi Parmar, Indira Unnikrishnan, Li Gong, Glen D. Raffel & Naomi Rosenberg. (2001) Temperature-Sensitive Transformation by an Abelson Virus Mutant Encoding an Altered SH2 Domain. Journal of Virology 75:4, pages 1816-1823.
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David Warren, Andrew J. Heilpern, Kent Berg & Naomi Rosenberg. (2000) The Carboxyl Terminus of v-Abl Protein Can Augment SH2 Domain Function. Journal of Virology 74:10, pages 4495-4504.
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Emmanuel Fournier, Pamela Blaikie, Olivier Rosnet, Benjamin Margolis, Daniel Birnbaum & Jean-Paul Borg. (1999) Role of tyrosine residues and protein interaction domains of SHC adaptor in VEGF Receptor 3 signaling. Oncogene 18:2, pages 507-514.
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