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Molecular and Cellular Biology Volume 13, 1993 - Issue 3
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Cell Growth and Development

SH1 Domain Autophosphorylation of P210 BCR/ABL Is Required for Transformation but Not Growth Factor Independence

Ann Marie Pendergast1 Department of Microbiology and Molecular Genetics, University of California, Los Angeles, California90024.;2 Molecular Biology Institute, University of California, Los Angeles, California90024.
,
Mikhail L. Gishizky1 Department of Microbiology and Molecular Genetics, University of California, Los Angeles, California90024.;2 Molecular Biology Institute, University of California, Los Angeles, California90024.;3 Howard Hughes Medical Institute, University of California, Los Angeles, California90024.
,
Marie H. Havlik3 Howard Hughes Medical Institute, University of California, Los Angeles, California90024.
&
Owen N. Witte1 Department of Microbiology and Molecular Genetics, University of California, Los Angeles, California90024.;2 Molecular Biology Institute, University of California, Los Angeles, California90024.;3 Howard Hughes Medical Institute, University of California, Los Angeles, California90024.
Pages 1728-1736 | Received 02 Jul 1992, Accepted 11 Dec 1992, Published online: 31 Mar 2023

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Moorthy SS Palanki, Jianguo Cao, Chun P Chow, Elena Dneprovskaia, Chi Ching Mak, Andrew McPherson, Ved P Pathak, Joel Renick, Richard Soll, Binqi Zeng & Glenn Noronha. (2009) Development of novel benzotriazines for drug discovery. Expert Opinion on Drug Discovery 4:1, pages 33-49.
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Lolita Banerji & Martin Sattler. (2004) Targeting mutated tyrosine kinases in the therapy of myeloid leukaemias. Expert Opinion on Therapeutic Targets 8:3, pages 221-239.
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Ryan P. Million, Nari Harakawa, Sergei Roumiantsev, Lyuba Varticovski & Richard A. Van Etten. (2004) A Direct Binding Site for Grb2 Contributes to Transformation and Leukemogenesis by the Tel-Abl (ETV6-Abl) Tyrosine Kinase. Molecular and Cellular Biology 24:11, pages 4685-4695.
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Gwen L. Nichols. (2003) Tyrosine Kinase Inhibitors as Cancer Therapy. Cancer Investigation 21:5, pages 758-771.
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Catherine M. Verfaillie, Pankaj Gupta, Felipe Prosper, Randy Hurley, Beverly Lundell & Ravi Bhatia. (1999) Stromal Extracellular Matrix Components As Growth Regulators For Human Hematopoietic Progenitors. Hematology 4:4, pages 321-333.
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Kristen Senechal, Conor Heaney, Brian Druker & Charles L. Sawyers. (1998) Structural Requirements for Function of the Crkl Adapter Protein in Fibroblasts and Hematopoietic Cells. Molecular and Cellular Biology 18:9, pages 5082-5090.
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Todd R. Golub, Andrei Goga, George F. Barker, Daniel E. H. Afar, Jami McLaughlin, Stefan K. Bohlander, Janet D. Rowley, Owen N. Witte & D. Gary Gilliland. (1996) Oligomerization of the ABL Tyrosine Kinase by the Ets Protein TEL in Human Leukemia. Molecular and Cellular Biology 16:8, pages 4107-4116.
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Jiaxin Liu, Yun Wu, Guo Zhen Ma, Dai Lu, Leena Haataja, Nora Heisterkamp, John Groffen & Ralph B. Arlinghaus. (1996) Inhibition of Bcr Serine Kinase by Tyrosine Phosphorylation. Molecular and Cellular Biology 16:3, pages 998-1005.
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David Cortez, Lisa Kadlec & Ann Marie Pendergast. (1995) Structural and Signaling Requirements for BCR-ABL-Mediated Transformation and Inhibition of Apoptosis. Molecular and Cellular Biology 15:10, pages 5531-5541.
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John R. McWhirter, Debora L. Galasso & Jean Y. J. Wang. (1993) A Coiled-Coil Oligomerization Domain of Bcr Is Essential for the Transforming Function of Bcr-Abl Oncoproteins. Molecular and Cellular Biology 13:12, pages 7587-7595.
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Andrei Goga, Jami McLaughlin, Ann Marie Pendergast, Kalindi Parmar, Alexander Muller, Naomi Rosenberg & Owen N. Witte. (1993) Oncogenic Activation of c-ABL by Mutation within Its Last Exon. Molecular and Cellular Biology 13:8, pages 4967-4975.
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C. L. Sawyers. (1993) Molecular Consequences of the BCR-ABL Translocation in Chronic Myelogenous Leukemia. Leukemia & Lymphoma 11:sup2, pages 101-103.
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Articles from other publishers (3)

Li Gong, Indira Unnikrishnan, Anuradha Raghavan, Kalindi Parmar & Naomi Rosenberg. (2004) Active Akt and Functional p53 Modulate Apoptosis in Abelson Virus-Transformed Pre-B Cells. Journal of Virology 78:4, pages 1636-1644.
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Celine A. Mainville, Kalindi Parmar, Indira Unnikrishnan, Li Gong, Glen D. Raffel & Naomi Rosenberg. (2001) Temperature-Sensitive Transformation by an Abelson Virus Mutant Encoding an Altered SH2 Domain. Journal of Virology 75:4, pages 1816-1823.
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David Warren, Andrew J. Heilpern, Kent Berg & Naomi Rosenberg. (2000) The Carboxyl Terminus of v-Abl Protein Can Augment SH2 Domain Function. Journal of Virology 74:10, pages 4495-4504.
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