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Transcriptional Regulation

Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region

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Pages 268-276 | Received 14 Jun 1993, Accepted 01 Oct 1993, Published online: 30 Mar 2023

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Benoit Grondin, Martin Lefrancois, Mathieu Tremblay, Marianne Saint-Denis, André Haman, Kazuo Waga, André Bédard, Daniel G. Tenen & Trang Hoang. (2007) c-Jun Homodimers Can Function as a Context-Specific Coactivator. Molecular and Cellular Biology 27:8, pages 2919-2933.
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Janki Rangatia, Rajani Kanth Vangala, Nicolai Treiber, Pu Zhang, Hanna Radomska, Daniel G. Tenen, Wolfgang Hiddemann & Gerhard Behre. (2002) Downregulation of c-Jun Expression by Transcription Factor C/EBPα Is Critical for Granulocytic Lineage Commitment. Molecular and Cellular Biology 22:24, pages 8681-8694.
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Charles Vinson, Max Myakishev, Asha Acharya, Alain A. Mir, Jonathan R. Moll & Maria Bonovich. (2002) Classification of Human B-ZIP Proteins Based on Dimerization Properties. Molecular and Cellular Biology 22:18, pages 6321-6335.
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Songyun Zhu, Hye-Sun Oh, Minsub Shim, Esta Sterneck, Peter F. Johnson & Robert C. Smart. (1999) C/EBPβ Modulates the Early Events of Keratinocyte Differentiation Involving Growth Arrest and Keratin 1 and Keratin 10 Expression. Molecular and Cellular Biology 19:10, pages 7181-7190.
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Alexander Zagariya, Shubhangee Mungre, Rosa Lovis, Michael Birrer, Scott Ness, Bayar Thimmapaya & Richard Pope. (1998) Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun. Molecular and Cellular Biology 18:5, pages 2815-2824.
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Robert G. Hawley & Lloyd C. Berger. (1998) Growth Control Mechanisms in Multiple Myeloma. Leukemia & Lymphoma 29:5-6, pages 465-475.
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Alexey M. Chumakov, Isabelle Grillier, Ekaterina Chumakova, Doris Chih, James Slater & H. Phillip Koeffler. (1997) Cloning of the Novel Human Myeloid-Cell-Specific C/EBP-ε Transcription Factor. Molecular and Cellular Biology 17:3, pages 1375-1386.
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Edward T. Morgan. (1997) Regulation of Cytochromes P450 During Inflammation and Infection. Drug Metabolism Reviews 29:4, pages 1129-1188.
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Luo-Hua Miau, Ching-Jin Chang, Wen-Hai Tsai & Sheng-Chung Lee. (1997) Identification and Characterization of a Nucleolar Phosphoprotein, Nopp140, as a Transcription Factor. Molecular and Cellular Biology 17:1, pages 230-239.
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Sigrun Mink, Ulrike Kerber & Karl-Heinz Klempnauer. (1996) Interaction of C/EBPβ and v-Myb Is Required for Synergistic Activation of the mim-1 Gene. Molecular and Cellular Biology 16:4, pages 1316-1325.
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Susanne Heiland & Rolf Knippers. (1995) The Human Topoisomerase I Gene Promoter Is Regulated by NF-IL6. Molecular and Cellular Biology 15:12, pages 6623-6631.
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Junichi Tsukada, Kazuyoshi Saito, Wayne R. Waterman, Andrew C. Webb & Philip E. Auron. (1994) Transcription Factors NF-IL6 and CREB Recognize a Common Essential Site in the Human Prointerleukin 1β Gene. Molecular and Cellular Biology 14:11, pages 7285-7297.
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Nabeel R. Yaseen, Jungchan Park, Tom Kerppola, Tom Curran & Surendra Sharma. (1994) A Central Role for Fos in Human B- and T-Cell NFAT (Nuclear Factor of Activated T Cells): an Acidic Region Is Required for In Vitro Assembly. Molecular and Cellular Biology 14:10, pages 6886-6895.
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Lidija Klampfer, Tae Ho Lee, Wei Hsu, Jan Vilček & Selina Chen-Kiang. (1994) NF-IL6 and AP-1 Cooperatively Modulate the Activation of the TSG-6 Gene by Tumor Necrosis Factor Alpha and Interleukin-1. Molecular and Cellular Biology 14:10, pages 6561-6569.
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Lizhen Wang, Natalie A. Rodrigues, Ying Wu, Bart M. Maslikowski, Nishi Singh, Samantha Lacroix & Pierre-André Bédard. (2011) Pleiotropic Action of AP-1 in v-Src-Transformed Cells. Journal of Virology 85:13, pages 6725-6735.
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Satoshi Uematsu, Tsuneyasu Kaisho, Takashi Tanaka, Makoto Matsumoto, Megumi Yamakami, Hiroko Omori, Masahiro Yamamoto, Tamotsu Yoshimori & Shizuo Akira. (2007) The C/EBPβ Isoform 34-kDa LAP Is Responsible for NF-IL-6-Mediated Gene Induction in Activated Macrophages, but Is Not Essential for Intracellular Bacteria Killing. The Journal of Immunology 179:8, pages 5378-5386.
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Joshua R. Friedman, Brian Larris, Phillip P. Le, T. Harshani Peiris, Athanasios Arsenlis, Jonathan Schug, John W. Tobias, Klaus H. Kaestner & Linda E. Greenbaum. (2004) Orthogonal analysis of C/EBPβ targets in vivo during liver proliferation . Proceedings of the National Academy of Sciences 101:35, pages 12986-12991.
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Ellora Sen, Samina Alam & Craig Meyers. (2004) Genetic and Biochemical Analysis of cis Regulatory Elements within the Keratinocyte Enhancer Region of the Human Papillomavirus Type 31 Upstream Regulatory Region during Different Stages of the Viral Life Cycle . Journal of Virology 78:2, pages 612-629.
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Caroline A Heckman, Melissa A Wheeler & Linda M Boxer. (2003) Regulation of Bcl-2 expression by C/EBP in t(14;18) lymphoma cells. Oncogene 22:39, pages 7891-7899.
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Dirk Hadaschik, Korinna Hinterkeuser, Monika Oldak, Herbert J. Pfister & Sigrun Smola-Hess. (2003) The Papillomavirus E2 Protein Binds to and Synergizes with C/EBP Factors Involved in Keratinocyte Differentiation. Journal of Virology 77:9, pages 5253-5265.
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Min Young Lee, Che-Hun Jung, Keesook Lee, Yung Hyun Choi, SunHwa Hong & JaeHun Cheong. (2002) Activating Transcription Factor-2 Mediates Transcriptional Regulation of Gluconeogenic Gene PEPCK by Retinoic Acid. Diabetes 51:12, pages 3400-3407.
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Christoffer Gebhardt, Ute Breitenbach, Jan Peter Tuckermann, Bernd Thilo Dittrich, Karl Hartmut Richter & Peter Angel. (2002) Calgranulins S100A8 and S100A9 are negatively regulated by glucocorticoids in a c-Fos-dependent manner and overexpressed throughout skin carcinogenesis. Oncogene 21:27, pages 4266-4276.
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Ellora Sen, Jennifer L. Bromberg-White & Craig Meyers. (2002) Genetic Analysis of cis Regulatory Elements within the 5′ Region of the Human Papillomavirus Type 31 Upstream Regulatory Region during Different Stages of the Viral Life Cycle . Journal of Virology 76:10, pages 4798-4809.
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Chun-sheng Mao & Janet Stavnezer. (2001) Differential Regulation of Mouse Germline Ig γ1 and ε Promoters by IL-4 and CD40. The Journal of Immunology 167:3, pages 1522-1534.
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Yurii Chinenov & Tom K Kerppola. (2001) Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20:19, pages 2438-2452.
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Mark Gagliardi, Scott Maynard, Bojana Bojovic & Pierre-André Bédard. (2001) The constitutive activation of the CEF-4/9E3 chemokine gene depends on C/EBPβ in v-src transformed chicken embryo fibroblasts. Oncogene 20:18, pages 2301-2313.
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Ching-Hung Shen & Janet Stavnezer. (2001) Activation of the Mouse Ig Germline ε Promoter by IL-4 Is Dependent on AP-1 Transcription Factors. The Journal of Immunology 166:1, pages 411-423.
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Chao-Kuen Lai & Ling-Pai Ting. (1999) Transcriptional Repression of Human Hepatitis B Virus Genes by a bZIP Family Member, E4BP4. Journal of Virology 73:4, pages 3197-3209.
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Livio Azzoni, Olga Zatsepina, Bekele Abebe, Ian M. Bennett, Palanisamy Kanakaraj & Bice Perussia. (1998) Differential Transcriptional Regulation of CD161 and a Novel Gene, 197/15a , by IL-2, IL-15, and IL-12 in NK and T Cells . The Journal of Immunology 161:7, pages 3493-3500.
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Tobias Bauknecht & Yang Shi. (1998) Overexpression of C/EBPβ Represses Human Papillomavirus Type 18 Upstream Regulatory Region Activity in HeLa Cells by Interfering with the Binding of TATA-Binding Protein. Journal of Virology 72:3, pages 2113-2124.
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Theodore C. Lee, Linheng Li, Lennart Philipson & Edward B. Ziff. (1997) Myc represses transcription of the growth arrest gene  gas1 . Proceedings of the National Academy of Sciences 94:24, pages 12886-12891.
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Ryuya Yamanaka, Gun-Do Kim, Hanna S. Radomska, Julie Lekstrom-Himes, Laura T. Smith, Per Antonson, Daniel G. Tenen & Kleanthis G. Xanthopoulos. (1997) CCAAT/enhancer binding protein ɛ is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing. Proceedings of the National Academy of Sciences 94:12, pages 6462-6467.
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