Advanced search
Publication Cover
Molecular and Cellular Biology Volume 14, 1994 - Issue 5
Submit an article Journal homepage
4
Views
8
CrossRef citations to date
0
Altmetric
Gene Expression

Mutations in the GCD7 Subunit of Yeast Guanine Nucleotide Exchange Factor eIF-2B Overcome the Inhibitory Effects of Phosphorylated eIF-2 on Translation Initiation

Carlos R. Vazquez De AldanaSection on Molecular Genetics of Lower Eukaryotes, Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, Maryland20892
&
Alan G. HinnebuschSection on Molecular Genetics of Lower Eukaryotes, Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, Maryland20892
Pages 3208-3222 | Received 18 Oct 1993, Accepted 10 Feb 1994, Published online: 30 Mar 2023

Citations (8)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (7)

Kamal Dev, Hongfang Qiu, Jinsheng Dong, Fan Zhang, Dominik Barthlme & Alan G. Hinnebusch. (2010) The β/Gcd7 Subunit of Eukaryotic Translation Initiation Factor 2B (eIF2B), a Guanine Nucleotide Exchange Factor, Is Crucial for Binding eIF2 In Vivo. Molecular and Cellular Biology 30:21, pages 5218-5233.
Read now
Jonathan P. Richardson, Sarah S. Mohammad & Graham D. Pavitt. (2004) Mutations Causing Childhood Ataxia with Central Nervous System Hypomyelination Reduce Eukaryotic Initiation Factor 2B Complex Formation and Activity. Molecular and Cellular Biology 24:6, pages 2352-2363.
Read now
Thanuja Krishnamoorthy, Graham D. Pavitt, Fan Zhang, Thomas E. Dever & Alan G. Hinnebusch. (2001) Tight Binding of the Phosphorylated α Subunit of Initiation Factor 2 (eIF2α) to the Regulatory Subunits of Guanine Nucleotide Exchange Factor eIF2B Is Required for Inhibition of Translation Initiation. Molecular and Cellular Biology 21:15, pages 5018-5030.
Read now
Graham D. Pavitt, Weimin Yang & Alan G. Hinnebusch. (1997) Homologous Segments in Three Subunits of the Guanine Nucleotide Exchange Factor eIF2B Mediate Translational Regulation by Phosphorylation of eIF2. Molecular and Cellular Biology 17:3, pages 1298-1313.
Read now
Weimin Yang & Alan G. Hinnebusch. (1996) Identification of a Regulatory Subcomplex in the Guanine Nucleotide Exchange Factor eIF2B That Mediates Inhibition by Phosphorylated eIF2. Molecular and Cellular Biology 16:11, pages 6603-6616.
Read now
Thomas E. Dever, Weimin Yang, Stefan Åström, Anders S. Byström & Alan G. Hinnebusch. (1995) Modulation of tRNA(iMet), eIF-2, and eIF-2B Expression Shows that GCN4 Translation Is Inversely Coupled to the Level of eIF-2·GTP·Met-tRNA(iMet) Ternary Complexes. Molecular and Cellular Biology 15:11, pages 6351-6363.
Read now
Carlos R. Vazquez De Aldana, Ronald C. Wek, Pedro San Segundo, Alexander G. Truesdell & Alan G. Hinnebusch. (1994) Multicopy tRNA Genes Functionally Suppress Mutations in Yeast eIF-2α Kinase GCN2: Evidence for Separate Pathways Coupling GCN4 Expression to Uncharged tRNA. Molecular and Cellular Biology 14:12, pages 7920-7932.
Read now

Articles from other publishers (1)

Rachel Elsby, Joshua F. Heiber, Peter Reid, Scot R. Kimball, Graham D. Pavitt & Glen N. Barber. (2011) The Alpha Subunit of Eukaryotic Initiation Factor 2B (eIF2B) Is Required for eIF2-Mediated Translational Suppression of Vesicular Stomatitis Virus. Journal of Virology 85:19, pages 9716-9725.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.