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Molecular and Cellular Biology Volume 14, 1994 - Issue 9
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Transcriptional Regulation

Identification of Functional Domains of the Aryl Hydrocarbon Receptor Nuclear Translocator Protein (ARNT)

Suzanne Reisz-Porszasz1 Laboratory of Structural Biology and Molecular Medicine, University of California, Los Angeles, California90024-1786
,
Markus R. Probst1 Laboratory of Structural Biology and Molecular Medicine, University of California, Los Angeles, California90024-1786
,
Bert N. Fukunaga1 Laboratory of Structural Biology and Molecular Medicine, University of California, Los Angeles, California90024-1786;2 Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California90024-1786
&
Oliver Hankinson1 Laboratory of Structural Biology and Molecular Medicine, University of California, Los Angeles, California90024-1786;2 Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California90024-1786Correspondence[email protected]
Pages 6075-6086 | Received 18 Apr 1994, Accepted 18 Jun 1994, Published online: 30 Mar 2023

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Ali Q Khazaal, Cassie D Jaeger, Kathleen M Bottum & Shelley A Tischkau. (2018) Environmental factors act through aryl hydrocarbon receptor activation and circadian rhythm disruption to regulate energy metabolism. Journal of Receptor, Ligand and Channel Research 10, pages 13-24.
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Sucharita Sen Banerjee, Mahesh Thirunavukkarasu, Muhammad Tipu Rishi, Juan A. Sanchez, Nilanjana Maulik & Gautam Maulik. (2012) HIF–prolyl hydroxylases and cardiovascular diseases. Toxicology Mechanisms and Methods 22:5, pages 347-358.
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Sayuri Shimazu, Yukiko Kawabata, Akito Inayoshi, Hideyuki Inui, Hitoshi Ashida & Hideo Ohkawa. (2010) Recombinant human AhR-mediated GUS reporter gene assays for PCB congeners in transgenic tobacco plants in comparison with recombinant mouse and guinea pig AhRs. Journal of Environmental Science and Health, Part B 45:8, pages 741-749.
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Katalin Monostory, Jean-Marc Pascussi, László Kóbori & Zdenek Dvorak. (2009) Hormonal regulation of CYP1A expression. Drug Metabolism Reviews 41:4, pages 547-572.
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Timothy V. Beischlag, Song Wang, David W. Rose, Joseph Torchia, Suzanne Reisz-Porszasz, Khurshid Muhammad, Walter E. Nelson, Markus R. Probst, Michael G. Rosenfeld & Oliver Hankinson. (2002) Recruitment of the NCoA/SRC-1/p160 Family of Transcriptional Coactivators by the Aryl Hydrocarbon Receptor/Aryl Hydrocarbon Receptor Nuclear Translocator Complex. Molecular and Cellular Biology 22:12, pages 4319-4333.
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Ping Cheng, Yuhong Yang, Kevin H. Gardner & Yi Liu. (2002) PAS Domain-Mediated WC-1/WC-2 Interaction Is Essential for Maintaining the Steady-State Level of WC-1 and the Function of Both Proteins in Circadian Clock and Light Responses of Neurospora. Molecular and Cellular Biology 22:2, pages 517-524.
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Richard S. Pollenz & E. Rick Barbour. (2000) Analysis of the Complex Relationship between Nuclear Export and Aryl Hydrocarbon Receptor-Mediated Gene Regulation. Molecular and Cellular Biology 20:16, pages 6095-6104.
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Choogon Lee, Kiho Bae & Isaac Edery. (1999) PER and TIM Inhibit the DNA Binding Activity of a Drosophila CLOCK-CYC/dBMAL1 Heterodimer without Disrupting Formation of the Heterodimer: a Basis for Circadian Transcription. Molecular and Cellular Biology 19:8, pages 5316-5325.
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Ingemar Pongratz, Camilla Antonsson, Murray L. Whitelaw & Lorenz Poellinger. (1998) Role of the PAS Domain in Regulation of Dimerization and DNA Binding Specificity of the Dioxin Receptor. Molecular and Cellular Biology 18:7, pages 4079-4088.
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Peter Moffett, Mark Reece & Jerry Pelletier. (1997) The Murine Sim-2 Gene Product Inhibits Transcription by Active Repression and Functional Interference. Molecular and Cellular Biology 17:9, pages 4933-4947.
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Hyunsung P. Ko, Steven T. Okino, Qiang Ma & James P. Whitlock$suffix/text()$suffix/text(). (1997) Transactivation Domains Facilitate Promoter Occupancy for the Dioxin-Inducible CYP1A1 Gene In Vivo. Molecular and Cellular Biology 17:7, pages 3497-3507.
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J. Craig Rowlands & Jan-Åke Gustafsson. (1997) Aryl Hydrocarbon Receptor-Mediated Signal Transduction. Critical Reviews in Toxicology 27:2, pages 109-134.
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James P. Whitlock, Christine H. Chichester, Robert M. Bedgood, Steven T. Okino, Hyunsung P. Ko, Qiang Ma, Liqun Dong, Hui Li & Regina Clarkekatzenberg. (1997) Induction of Drug-Metabolizing Enzymes by Dioxin. Drug Metabolism Reviews 29:4, pages 1107-1127.
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Jo A. Forsythe, Bing-Hua Jiang, Narayan V. Iyer, Faton Agani, Sandra W. Leung, Robert D. Koos & Gregg L. Semenza. (1996) Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1. Molecular and Cellular Biology 16:9, pages 4604-4613.
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Ken Hirose, Masanobu Morita, Masatsugu Ema, Junsei Mimura, Hiroshi Hamada, Hideta Fujii, Yukio Saijo, Osamu Gotoh, Kazuhiro Sogawa & Yoshiaki Fujii-Kuriyama. (1996) cDNA Cloning and Tissue-Specific Expression of a Novel Basic Helix-Loop-Helix/PAS Factor (Arnt2) with Close Sequence Similarity to the Aryl Hydrocarbon Receptor Nuclear Translocator (Arnt). Molecular and Cellular Biology 16:4, pages 1706-1713.
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Articles from other publishers (8)

Sarah V Mendoza, Damian C Genetos & Clare E Yellowley. (2023) Hypoxia‐Inducible Factor‐2α Signaling in the Skeletal System. JBMR Plus 7:4.
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Jingyuan Wang, Peipei Lu & Wen Xie. (2023) Atypical functions of xenobiotic receptors in lipid and glucose metabolism. Medical Review 2:6, pages 611-624.
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Amy I.H. Hrdina, Ishwar N. Kohale, Simran Kaushal, Jamie Kelly, Noelle E. Selin, Bevin P. Engelward & Jesse H. Kroll. (2022) The Parallel Transformations of Polycyclic Aromatic Hydrocarbons in the Body and in the Atmosphere. Environmental Health Perspectives 130:2.
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Shutang ZhouSimone DeganErin N. Potts, W. Michael Foster & Mary E. Sunday. (2009) NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proceedings of the National Academy of Sciences 106:28, pages 11691-11696.
Crossref
Sara Brunnberg, Katarina Pettersson, Elin Rydin, Jason Matthews, Annika Hanberg & Ingemar Pongratz. (2003) The basic helix–loop–helix–PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription. Proceedings of the National Academy of Sciences 100:11, pages 6517-6522.
Crossref
L. Eric Huang, Jie Gu, Maureen Schau & H. Franklin Bunn. (1998) Regulation of hypoxia-inducible factor 1α is mediated by an O 2 -dependent degradation domain via the ubiquitin-proteasome pathway . Proceedings of the National Academy of Sciences 95:14, pages 7987-7992.
Crossref
Pekka J. Kallio, Ingemar Pongratz, Katarina Gradin, Jacqueline McGuire & Lorenz Poellinger. (1997) Activation of hypoxia-inducible factor 1α: Posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor. Proceedings of the National Academy of Sciences 94:11, pages 5667-5672.
Crossref
Yu-Dong Zhou, Mary Barnard, Hui Tian, Xu Li, Huijun Z. Ring, Uta Francke, John Shelton, James Richardson, David W. Russell & Steven L. McKnight. (1997) Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system. Proceedings of the National Academy of Sciences 94:2, pages 713-718.
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