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Gene Expression

Introns are cis Effectors of the Nonsense-Codon-Mediated Reduction in Nuclear mRNA Abundance

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Pages 6317-6325 | Received 13 Apr 1994, Accepted 16 Jun 1994, Published online: 30 Mar 2023

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Kavitha S. Rajavel & Elizabeth F. Neufeld. (2001) Nonsense-Mediated Decay of HumanHEXA mRNA. Molecular and Cellular Biology 21:16, pages 5512-5519.
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Guillaume Serin, Anand Gersappe, Jennifer D. Black, Rachel Aronoff & Lynne E. Maquat. (2001) Identification and Characterization of Human Orthologues to Saccharomyces cerevisiae Upf2 Protein and Upf3 Protein (Caenorhabditis elegans SMG-4). Molecular and Cellular Biology 21:1, pages 209-223.
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Joshua T. Mendell, Susan M. Medghalchi, Ross G. Lake, Erick N. Noensie & Harry C. Dietz. (2000) Novel Upf2p Orthologues Suggest a Functional Link between Translation Initiation and Nonsense Surveillance Complexes. Molecular and Cellular Biology 20:23, pages 8944-8957.
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Jing Zhang, Xiaolei Sun, Yimei Qian, Jeffrey P. LaDuca & Lynne E. Maquat. (1998) At Least One Intron Is Required for the Nonsense-Mediated Decay of Triosephosphate Isomerase mRNA: a Possible Link between Nuclear Splicing and Cytoplasmic Translation. Molecular and Cellular Biology 18:9, pages 5272-5283.
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Ofra Kessler & Lawrence A. Chasin. (1996) Effects of Nonsense Mutations on Nuclear and Cytoplasmic Adenine Phosphoribosyltransferase RNA. Molecular and Cellular Biology 16:8, pages 4426-4435.
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Phillip Belgrader, Jiu Cheng, Xianbo Zhou, Lori S. Stephenson & Lynne E. Maquat. (1994) Mammalian Nonsense Codons Can Be cis Effectors of Nuclear mRNA Half-Life. Molecular and Cellular Biology 14:12, pages 8219-8228.
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Arcangela De Nicolo, Mariella Tancredi, Grazia Lombardi, Cristina Chantal Flemma, Serena Barbuti, Claudio Di Cristofano, Bijan Sobhian, Generoso Bevilacqua, Ronny Drapkin & Maria Adelaide Caligo. (2008) A Novel Breast Cancer–Associated BRIP1 ( FANCJ/BACH1 ) Germ-line Mutation Impairs Protein Stability and Function . Clinical Cancer Research 14:14, pages 4672-4680.
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Daehyun Baek & Phil Green. (2005) Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing. Proceedings of the National Academy of Sciences 102:36, pages 12813-12818.
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Jun Wang, Jayanthi P Gudikote, O Renee Olivas & Miles F Wilkinson. (2002) Boundary‐independent polar nonsense‐mediated decay. EMBO reports 3:3, pages 274-279.
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Yumiko Watanabe, Katharine E. Magor & Peter Parham. (2001) Exon 5 Encoding the Transmembrane Region of HLA-A Contains a Transitional Region for the Induction of Nonsense-Mediated mRNA Decay. The Journal of Immunology 167:12, pages 6901-6911.
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Xiaolei Sun, Haley A. Perlick, Harry C. Dietz & Lynne E. Maquat. (1998) A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsensecontaining mRNAs in mammalian cells. Proceedings of the National Academy of Sciences 95:17, pages 10009-10014.
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