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Molecular and Cellular Biology Volume 8, 1988 - Issue 8
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Research Article

p21-ras Effector Domain Mutants Constructed by "Cassette" Mutagenesis

James C. Stone1 Jackson Laboratory, Bar Harbor, Maine04609
,
William C. Vass2 Laboratory of Cellular Oncology, National Cancer Institute, Bethesda, Maryland20892
,
Berthe M. Willumsen3 University Microbiology Institute, Copenhagen, Denmark
&
Douglas R. Lowy2 Laboratory of Cellular Oncology, National Cancer Institute, Bethesda, Maryland20892
Pages 3565-3569 | Received 18 Feb 1988, Accepted 17 May 1988, Published online: 31 Mar 2023

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Stacey Stang, Drell Bottorff & James C. Stone. (1997) Interaction of Activated Ras with Raf-1 Alone May Be Sufficient for Transformation of rat2 Cells. Molecular and Cellular Biology 17:6, pages 3047-3055.
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Drell Bottorff, Stacey Stang, Sherry Agellon & James C. Stone. (1995) RAS Signalling Is Abnormal in a c-raf1 MEK1 Double Mutant. Molecular and Cellular Biology 15:9, pages 5113-5122.
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James C. Stone, Micheal Colleton & Darrel Bottorff. (1993) Effector Domain Mutations Dissociate p21 Effector Function and GTPase-Activating Protein Interaction. Molecular and Cellular Biology 13:12, pages 7311-7320.
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James C. Stone & Rachel A. Blanchard. (1991) Genetic Definition of ras Effector Elements. Molecular and Cellular Biology 11:12, pages 6158-6165.
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Jeffrey E. Declue, James C. Stone, Rachel A. Blanchard, Alex G. Papageorge, Patrick Martin, Ke Zhang & Douglas R. Lowy. (1991) A ras Effector Domain Mutant Which Is Temperature Sensitive for Cellular Transformation: Interactions with GTPase-Activating Protein and NF-1. Molecular and Cellular Biology 11:6, pages 3132-3138.
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Padmini S. Kedar, Douglas R. Lowy, Steven G. Widen & Samuel H. Wilson. (1990) Transfected Human β-Polymerase Promoter Contains a ras-Responsive Element. Molecular and Cellular Biology 10:7, pages 3852-3856.
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JamesM. Chen, Grace Lee, RandallB. Murphy, RobertP. Carty, PaulW. Brandt-Rauf, Edward Friedman & MatthewR. Pincus. (1989) Comparison of the Computed Structures for the Phosphate-Binding Loop of the p21 Protein Containing the Oncogenic Site Gly 12 with the X-ray Crystallographic Structures for this Region in the p21 Protein and EFtu. A Model for the Structure of the p21 Protein in its Oncogenic Form. Journal of Biomolecular Structure and Dynamics 6:5, pages 859-875.
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