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Cell and Organelle Structure and Assembly

Tau Consists of a Set of Proteins with Repeated C-Terminal Microtubule-Binding Domains and Variable N-Terminal Domains

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Pages 1381-1388 | Received 17 Oct 1988, Accepted 29 Dec 1988, Published online: 31 Mar 2023

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Yurika Hashi, Susumu Kotani & Takeshi Adachi. (2016) A nematode microtubule-associated protein, PTL-1, closely resembles its mammalian counterparts in overall molecular architecture. Bioscience, Biotechnology, and Biochemistry 80:6, pages 1107-1113.
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Tal Sines, Shira Granot-Attas, Sabrina Weisman-Welcher & Ari Elson. (2007) Association of Tyrosine Phosphatase Epsilon with Microtubules Inhibits Phosphatase Activity and Is Regulated by the Epidermal Growth Factor Receptor. Molecular and Cellular Biology 27:20, pages 7102-7112.
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Alistair J Stewart, Anthony Fox, Bruce H Morimoto & Illana Gozes. (2007) Looking for novel ways to treat the hallmarks of Alzheimer's disease. Expert Opinion on Investigational Drugs 16:8, pages 1183-1196.
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Sang Ho Chung. (1997) The C‐terminal region of human tau protein with ability of filament formation. Korean Journal of Biological Sciences 1:2, pages 317-321.
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Neerja Sethi, M. Cristina Monteagudo, Douglas Koshland, Eileen Hogan & Daniel J. Burke. (1991) The CDC20 Gene Product of Saccharomyces cerevisiae, a β-Transducin Homolog, Is Required for a Subset of Microtubule-Dependent Cellular Processes. Molecular and Cellular Biology 11:11, pages 5592-5602.
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Manley T. F. Huang & Cornelia M. Gorman. (1990) The Simian Virus 40 Small-t Intron, Present in Many Common Expression Vectors, Leads to Aberrant Splicing. Molecular and Cellular Biology 10:4, pages 1805-1810.
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Adolf Himmler. (1989) Structure of the Bovine Tau Gene: Alternatively Spliced Transcripts Generate a Protein Family. Molecular and Cellular Biology 9:4, pages 1389-1396.
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Viet Hoang Man, Xibing He, Fengyang Han, Lianjin Cai, Luxuan Wang, Taoyu Niu, Jingchen Zhai, Beihong Ji, Jie Gao & Junmei Wang. (2023) Phosphorylation at Ser289 Enhances the Oligomerization of Tau Repeat R2. Journal of Chemical Information and Modeling 63:4, pages 1351-1361.
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Viet Hoang Man, Xibing He, Jie Gao & Junmei Wang. (2023) Phosphorylation of Tau R2 Repeat Destabilizes Its Binding to Microtubules: A Molecular Dynamics Simulation Study. ACS Chemical Neuroscience 14:3, pages 458-467.
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Murat Serdar Gurses, Mustafa Numan Ural, Mehmet Akif Gulec, Omer Akyol & Sumeyya Akyol. (2016) Pathophysiological Function of ADAMTS Enzymes on Molecular Mechanism of Alzheimer’s Disease. Aging and disease 7:4, pages 479.
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Peter J. ChungMyung Chul ChoiHerbert P. MillerH. Eric FeinsteinUri RavivYouli Li, Leslie WilsonStuart C. FeinsteinCyrus R. Safinya. (2015) Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules. Proceedings of the National Academy of Sciences 112:47.
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Kenneth J. RosenbergJennifer L. Ross, H. Eric Feinstein, Stuart C. Feinstein & Jacob Israelachvili. (2008) Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis. Proceedings of the National Academy of Sciences 105:21, pages 7445-7450.
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Markus Schubert, Dinesh Gautam, David Surjo, Kojihiko Ueki, Stephanie Baudler, Dominic Schubert, Tatsuya Kondo, Jens Alber, Norbert Galldiks, Eckehardt Küstermann, Saskia Arndt, Andreas H. Jacobs, Wilhelm Krone, C. Ronald Kahn & Jens C. Brüning. (2004) Role for neuronal insulin resistance in neurodegenerative diseases. Proceedings of the National Academy of Sciences 101:9, pages 3100-3105.
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Dulal Panda, Jonathan C. Samuel, Michelle Massie, Stuart C. Feinstein & Leslie Wilson. (2003) Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for the onset of neurodegenerative disease. Proceedings of the National Academy of Sciences 100:16, pages 9548-9553.
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Alejandra del C. Alonso, Tanweer Zaidi, Michal Novak, Inge Grundke-Iqbal & Khalid Iqbal. (2001) Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments. Proceedings of the National Academy of Sciences 98:12, pages 6923-6928.
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Youichi Kadota, Akiko Niiya, Ryuichi Masaki, Akitsugu Yamamoto, Masasuke Araki & Shigeru Taketani. (1997) A newly identified membrane protein localized exclusively in intracellular organelles of neurons. Molecular Brain Research 46:1-2, pages 265-273.
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