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Hematology Volume 16, 2011 - Issue 5
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Original Article

Quercetin-induced apoptosis involves increased hTERT enzyme activity of leukemic cells

Cigir Biray AvciDepartment of Medical BiologySchool of Medicine, Ege University, Izmir, Turkey
,
Sunde YilmazDepartment of Medical BiologySchool of Medicine, Ege University, Izmir, Turkey
,
Zeynep Ozlem DoganDepartment of Medical BiologySchool of Medicine, Ege University, Izmir, Turkey
,
Güray SaydamDepartment of HematologySchool of Medicine, Ege University, IzmirTurkey
,
Yavuz DodurgaSchool of MedicineDepartment of Medical Biology, School of Medicine, Pamukkale University, Denizli, Turkey
,
Huseyin Atakan EkizDepartment of Molecular Biology and Genetics Faculty of Science, Izmir Institute of Technology, Turkey
,
Melis KartalDepartment of Molecular Biology and Genetics Faculty of Science, Izmir Institute of Technology, Turkey
,
Fahri SahinDepartment of HematologySchool of Medicine, Ege University, IzmirTurkey
,
Yusuf BaranDepartment of Molecular Biology and Genetics Faculty of Science, Izmir Institute of Technology, TurkeyCorrespondence[email protected]
&
Cumhur GunduzDepartment of Medical BiologySchool of Medicine, Ege University, Izmir, Turkey
 show all
Pages 303-307 | Published online: 12 Nov 2013

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Mark A. Levy, Junqiang Tian, Mandi Gandelman, Haojie Cheng, Menelaos Tsapekos, Sara R. Crego, Rolando Maddela & Robert Sinnott. (2024) A Multivitamin Mixture Protects against Oxidative Stress-Mediated Telomere Shortening. Journal of Dietary Supplements 21:1, pages 53-70.
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Katrin Sak. (2014) Site-Specific Anticancer Effects of Dietary Flavonoid Quercetin. Nutrition and Cancer 66:2, pages 177-193.
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Articles from other publishers (22)

Esha S. Attar, Vanashree H. Chaudhari, Chaitanya G. Deokar, Sathish Dyawanapelly & Padma V. Devarajan. (2023) Nano Drug Delivery Strategies for an Oral Bioenhanced Quercetin Formulation. European Journal of Drug Metabolism and Pharmacokinetics 48:5, pages 495-514.
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Vincenzo Sorrenti, Alessandro Buriani, Stefano Fortinguerra, Sergio Davinelli, Giovanni Scapagnini, Aedin Cassidy & Immaculata De Vivo. (2023) Cell Survival, Death, and Proliferation in Senescent and Cancer Cells: the Role of (Poly)phenols. Advances in Nutrition.
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Neel Parekh, Ashish Garg, Renuka Choudhary, Madhu Gupta, Ginpreet Kaur, Seema Ramniwas, Moyad Shahwan, Hardeep Singh Tuli & Gautam Sethi. (2023) The Role of Natural Flavonoids as Telomerase Inhibitors in Suppressing Cancer Growth. Pharmaceuticals 16:4, pages 605.
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Harsh Goel, Rahul Kumar, Pranay Tanwar, Tarun Kumar Upadhyay, Fahad Khan, Pratibha Pandey, Sojin Kang, Myunghan Moon, Jinwon Choi, Min Choi, Moon Nyeo Park, Bonglee Kim & Mohd Saeed. (2023) Unraveling the therapeutic potential of natural products in the prevention and treatment of leukemia. Biomedicine & Pharmacotherapy 160, pages 114351.
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Keerti Vishwakarma, Rajdeep Dey & Hardik Bhatt. (2023) Telomerase: A prominent oncological target for development of chemotherapeutic agents. European Journal of Medicinal Chemistry 249, pages 115121.
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Noushin Lotfi, Zahra Yousefi, Marjan Golabi, Parvin Khalilian, Behrooz Ghezelbash, Mina Montazeri, Mohammad Hossein Shams, Parnian Zolfaghari Baghbadorani & Nahid Eskandari. (2023) The potential anti-cancer effects of quercetin on blood, prostate and lung cancers: An update. Frontiers in Immunology 14.
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Nada Oršolić & Maja Jazvinšćak Jembrek. (2022) Molecular and Cellular Mechanisms of Propolis and Its Polyphenolic Compounds against Cancer. International Journal of Molecular Sciences 23:18, pages 10479.
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Fatemeh Nabizadeh, Saeideh Momtaz, Maryam Ghanbari-Movahed, Farshad Qalekhani, Hadi Mohsenpour, Ina Yosifova Aneva, Anusha Bishayee, Mohammad Hosein Farzaei & Anupam Bishayee. (2022) Pediatric acute lymphoblastic leukemia management using multitargeting bioactive natural compounds: A systematic and critical review. Pharmacological Research 177, pages 106116.
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Raman Kumar, Nidhi Gupta & Alpana Sharma. 2022. Cancer Diagnostics and Therapeutics. Cancer Diagnostics and Therapeutics 303 331 .
Coralia Cotoraci, Alina Ciceu, Alciona Sasu, Eftimie Miutescu & Anca Hermenean. (2021) The Anti-Leukemic Activity of Natural Compounds. Molecules 26:9, pages 2709.
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Somayyeh Ghareghomi, Shahin Ahmadian, Nosratollah Zarghami & Houman Kahroba. (2021) Fundamental insights into the interaction between telomerase/TERT and intracellular signaling pathways. Biochimie 181, pages 12-24.
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Shalini Bajaj, Maushmi S Kumar, GJ Peters & YC Mayur. (2020) Targeting telomerase for its advent in cancer therapeutics. Medicinal Research Reviews 40:5, pages 1871-1919.
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Xing Chen, Wen‐Jian Tang, Jing Bo Shi, Ming Ming Liu & Xin‐Hua Liu. (2020) Therapeutic strategies for targeting telomerase in cancer. Medicinal Research Reviews 40:2, pages 532-585.
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Fabrizia Brisdelli, Laura Di Francesco, Alessandra Giorgi, Anna Rita Lizzi, Carla Luzi, Giuseppina Mignogna, Argante Bozzi & M. Eugenia Schininà. (2019) Proteomic Analysis of Quercetin-Treated K562 Cells. International Journal of Molecular Sciences 21:1, pages 32.
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HyunTae V. Hwang, Darlene Thuy Tran, Michelle Nicole Rebuffatti, Chin-Shang Li & Anne A. Knowlton. (2018) Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells. PLOS ONE 13:1, pages e0190374.
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Kumar Ganesan & Baojun Xu. (2017) Telomerase Inhibitors from Natural Products and Their Anticancer Potential. International Journal of Molecular Sciences 19:1, pages 13.
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Junn-Liang Chang, Jyh-Ming Chow, Jer-Hwa Chang, Yu-Ching Wen, Yung-Wei Lin, Shun-Fa Yang, Wei-Jiunn Lee & Ming-Hsien Chien. (2017) Quercetin simultaneously induces G 0 /G 1 -phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells . Environmental Toxicology 32:7, pages 1857-1868.
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Victor Maso, Andrana Karla Calgarotto, Gilberto Carlos FranchiJrJr, Alexandre Eduardo Nowill, Paulo Latuf Filho, José Vassallo & Sara Teresinha Olalla Saad. (2014) Multitarget Effects of Quercetin in Leukemia. Cancer Prevention Research 7:12, pages 1240-1250.
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Catherine Charles, Amandine Nachtergael, Moustapha Ouedraogo, Alexandra Belayew & Pierre Duez. (2014) Effects of chemopreventive natural products on non-homologous end-joining DNA double-strand break repair. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 768, pages 33-41.
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Juliana Poglia Carini, Fábio Klamt & Valquiria Linck Bassani. (2014) Flavonoids from Achyrocline satureioides: promising biomolecules for anticancer therapy. RSC Adv. 4:7, pages 3131-3144.
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. (2013) Current World Literature. Current Opinion in Lipidology 24:1, pages 86-94.
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Carmela Spagnuolo, Maria Russo, Stefania Bilotto, Idolo Tedesco, Bruna Laratta & Gian Luigi Russo. (2012) Dietary polyphenols in cancer prevention: the example of the flavonoid quercetin in leukemia. Annals of the New York Academy of Sciences 1259:1, pages 95-103.
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