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Redox Report
Communications in Free Radical Research
Volume 8, 2003 - Issue 4
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Research articles

Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction

Anna-Rebekka RessmeyerInstitut für Zoologie, Anthropologie und Entwicklungsbiologie, Universität Göttingen, Göttingen, Germany
,
Juan C. MayoDepartment of Cellular and Structural Biology The University of Texas Health Science Center, San Antonio, Texas, USA
,
Veronika ZeloskoInstitut für Zoologie, Anthropologie und Entwicklungsbiologie, Universität Göttingen, Göttingen, Germany
,
Rosa M. SáinzDepartment of Cellular and Structural Biology The University of Texas Health Science Center, San Antonio, Texas, USA
,
Dun-Xian TanDepartment of Cellular and Structural Biology The University of Texas Health Science Center, San Antonio, Texas, USA
,
Burkhard PoeggelerInstitut für Zoologie, Anthropologie und Entwicklungsbiologie, Universität Göttingen, Göttingen, Germany
,
Isaac AntolínDepartamento de Morfologí a y Biologí a Celular Universidad de Oviedo, Oviedo , Asturias, Spain
,
Beata K. ZsizsikInstitut für Zoologie, Anthropologie und Entwicklungsbiologie, Universität Göttingen, Göttingen, Germany
,
Russel J. ReiterDepartment of Cellular and Structural Biology The University of Texas Health Science Center, San Antonio, Texas, USA
&
Rüdiger HardelandInstitut für Zoologie, Anthropologie und Entwicklungsbiologie, Universität Göttingen, Göttingen, Germany
 show all
Pages 205-213 | Published online: 19 Jul 2013

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Yu-Qing Zhao, Zhong-Wei Zhang, Yang-Er Chen, Chun-Bang Ding, Shu Yuan, Russel J. Reiter & Ming Yuan. (2021) Melatonin: A Potential Agent in Delaying Leaf Senescence. Critical Reviews in Plant Sciences 40:1, pages 1-22.
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Konrad Kleszczynski & Tobias W. Fischer. (2012) Melatonin and human skin aging. Dermato-Endocrinology 4:3, pages 245-252.
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Birajalaxmi Das, Paula V. Bennett, Noelle C. Cutter, John C. Sutherland & Betsy M. Sutherland. (2011) Melatonin protects human cells from clustered DNA damages, killing and acquisition of soft agar growth induced by X-rays or 970 MeV/n Fe ions. International Journal of Radiation Biology 87:6, pages 545-555.
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Hsiao-Wen Lin & E-Jian Lee. (2009) Effects of melatonin in experimental stroke models in acute, sub-acute, and chronic stages. Neuropsychiatric Disease and Treatment 5, pages 157-162.
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Alexandra Nowak, Hafizur Rahman, Christina Heer, Anna Schueth, Hartmut Laatsch & Rüdiger Hardeland. (2008) Reactions of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK) with the tyrosine side-chain fragment, 4-ethylphenol. Redox Report 13:3, pages 102-108.
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Ozkan Ates, Suleyman Cayli, Iclal Gurses, Neslihan Yucel, Eyup Altinoz, Mustafa Iraz, Ayhan Kocak & Saim Yologlu. (2007) Does pinealectomy affect the recovery rate after spinal cord injury?. Neurological Research 29:6, pages 533-539.
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A. Grzelak & G. Bartosz. (2005) Melatonin does not affect total antioxidant capacity of blood plasma in vitro. Scandinavian Journal of Clinical and Laboratory Investigation 65:1, pages 77-81.
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Chao Gao, Hong‐Bing Han, Xiu‐Zhi Tian, Dun‐Xian Tan, Liang Wang, Guang‐Bin Zhou, Shi‐En Zhu & Guo‐Shi Liu. (2012) Melatonin promotes embryonic development and reduces reactive oxygen species in vitrified mouse 2‐cell embryos. Journal of Pineal Research 52:3, pages 305-311.
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Sergio A. Rosales‐Corral, Dario Acuña‐Castroviejo, Ana Coto‐Montes, Jose A. Boga, Lucien C. Manchester, Lorena Fuentes‐Broto, Ahmet Korkmaz, Shuran Ma, Dun‐ Xian Tan & Russel J. Reiter. (2011) Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin. Journal of Pineal Research 52:2, pages 167-202.
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Ahmet Korkmaz, Shuran Ma, Turgut Topal, Sergio Rosales-Corral, Dun-Xian Tan & Russel J. Reiter. (2012) Glucose: A vital toxin and potential utility of melatonin in protecting against the diabetic state. Molecular and Cellular Endocrinology 349:2, pages 128-137.
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Germaine Escames, Guler Ozturk, Beatriz Baño‐Otálora, María J. Pozo, Juan A. Madrid, Russel J. Reiter, Eric Serrano, Melquiades Concepción & Dario Acuña‐Castroviejo. (2011) Exercise and melatonin in humans: reciprocal benefits. Journal of Pineal Research 52:1, pages 1-11.
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Yan‐Li Ji, Hua Wang, Can Meng, Xian‐Feng Zhao, Cheng Zhang, Ying Zhang, Mei Zhao, Yuan‐Hua Chen, Xiu‐Hong Meng & De‐Xiang Xu. (2011) Melatonin alleviates cadmium‐induced cellular stress and germ cell apoptosis in testes. Journal of Pineal Research 52:1, pages 71-79.
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José C. Dayoub, Francisco Ortiz, Luis C. López, Carmen Venegas, Alberto del Pino-Zumaquero, Olga Roda, Indalecio Sánchez-Montesinos, Darío Acuña-Castroviejo & Germaine Escames. (2011) Synergism between melatonin and atorvastatin against endothelial cell damage induced by lipopolysaccharide. Journal of Pineal Research 51:3, pages 324-330.
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Catherine Marchetti, Nazha Sidahmed-Adrar, Fabrice Collin, Daniel Jore, Monique Gardès-Albert & Dominique Bonnefont-Rousselot. (2011) Melatonin protects PLPC liposomes and LDL towards radical-induced oxidation. Journal of Pineal Research 51:3, pages 286-296.
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Annia Galano, Dun Xian Tan & Russel J. Reiter. (2011) Melatonin as a natural ally against oxidative stress: a physicochemical examination. Journal of Pineal Research 51:1, pages 1-16.
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Seung-Il Choi, Shorafidinkhuja Dadakhujaev, Hyunmi Ryu, Tae im Kim & Eung Kweon Kim. (2011) Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors. Journal of Pineal Research 51:1, pages 94-103.
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Sara Succu, Fiammetta Berlinguer, Valeria Pasciu, Valentina Satta, Giovanni G Leoni & Salvatore Naitana. (2011) Melatonin protects ram spermatozoa from cryopreservation injuries in a dose-dependent manner. Journal of Pineal Research 50:3, pages 310-318.
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Emanuela Esposito, Irene Paterniti, Emanuela Mazzon, Placido Bramanti & Salvatore Cuzzocrea. (2010) Melatonin reduces hyperalgesia associated with inflammation. Journal of Pineal Research 49:4, pages 321-331.
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Sida Niu, Feng Li, Dun-Xian Tan, Lirong Zhang, Jeffrey R. Idle, Frank J. Gonzalez & Xiaochao Ma. (2010) Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice. Journal of Pineal Research 49:2, pages 106-114.
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Russel J Reiter, Lucien C Manchester, Lorena Fuentes-Broto & Dun-Xian Tan. (2010) Cardiac hypertrophy and remodelling: pathophysiological consequences and protective effects of melatonin. Journal of Hypertension 28:Suppl 1, pages S7-S12.
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Irene Crespo, Beatriz S. Miguel, Almudena Laliena, Marcelino Álvarez, Jesús M. Culebras, Javier González-Gallego & María J. Tuñón. (2010) Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin. Journal of Pineal Research, pages no-no.
Crossref
Valdecir F. Ximenes, Camila Z. Padovan, Danielle A. Carvalho & João Roberto Fernandes. (2010) Oxidation of melatonin by taurine chloramine. Journal of Pineal Research, pages no-no.
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Germaine Escames, Darío Acuña-Castroviejo, Luis Carlos López, Dun-xian Tan, Maria Dolores Maldonado, Marina Sánchez-Hidalgo, Josefa León & Russel J Reiter. (2006) Pharmacological utility of melatonin in the treatment of septic shock: experimental and clinical evidence. Journal of Pharmacy and Pharmacology 58:9, pages 1153-1165.
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D. Hevia, C. Botas, R.M. Sainz, I. Quiros, D. Blanco, D.X. Tan, C. Gomez-Cordoves & J.C. Mayo. (2010) Development and validation of new methods for the determination of melatonin and its oxidative metabolites by high performance liquid chromatography and capillary electrophoresis, using multivariate optimization. Journal of Chromatography A 1217:8, pages 1368-1374.
Crossref
Jana T. Kuesel, Rüdiger Hardeland, Henrike Pfoertner & Nelia Aeckerle. (2010) Reactions of the melatonin metabolite N 1 -acetyl-5-methoxykynuramine with carbamoyl phosphate and related compounds . Journal of Pineal Research 48:1, pages 47-54.
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Rüdiger Hardeland. (2009) Neuroprotection by Radical Avoidance: Search for Suitable Agents. Molecules 14:12, pages 5054-5102.
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Ismaël Yekini, Fatma Hammoudi, Françoise Martin-Nizard, Saïd Yous, Nicolas Lebegue, Pascal Berthelot & Pascal Carato. (2009) Antioxidant activity of benzoxazolinonic and benzothiazolinonic derivatives in the LDL oxidation model. Bioorganic & Medicinal Chemistry 17:22, pages 7823-7830.
Crossref
Youssef Hibaoui, Emmanuelle Roulet & Urs T. Ruegg. (2009) Melatonin prevents oxidative stress-mediated mitochondrial permeability transition and death in skeletal muscle cells. Journal of Pineal Research 47:3, pages 238-252.
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M. C. Reyes-Gonzales, L. Fuentes-Broto, E. Martínez-Ballarín, F. J. Miana-Mena, C. Berzosa, F. A. García-Gil, M. Aranda & J. J. García. (2009) Effects of Tryptophan and 5-Hydroxytryptophan on the Hepatic Cell Membrane Rigidity Due to Oxidative Stress. Journal of Membrane Biology 231:2-3, pages 93-99.
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Víctor Tapias, Germaine Escames, Luis C. López, Ana López, Encarnación Camacho, María D. Carrión, Antonio Entrena, Miguel A. Gallo, Antonio Espinosa & Darío Acuña-Castroviejo. (2009) Melatonin and its brain metabolite N 1 -acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice . Journal of Neuroscience Research 87:13, pages 3002-3010.
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Rüdiger Hardeland, Dun‐Xian Tan & Russel J. Reiter. (2009) Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. Journal of Pineal Research 47:2, pages 109-126.
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Alberto Domínguez-Rodríguez, Sima Samimi-Fard, Pedro Abreu-González & Juan Carlos Kaski. (2009) Melatonina y aterosclerosis coronaria. Clínica e Investigación en Arteriosclerosis 21:5, pages 247-256.
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Meike Schaefer & Rüdiger Hardeland. (2009) The melatonin metabolite N 1 -acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger . Journal of Pineal Research 46:1, pages 49-52.
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H. M. Yeung, M. W. Hung & M. L. Fung. (2008) Melatonin ameliorates calcium homeostasis in myocardial and ischemia-reperfusion injury in chronically hypoxic rats. Journal of Pineal Research 45:4, pages 373-382.
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Valdecir F. Ximenes. (2008) Optimized synthesis of the melatonin metabolite N 1 -acetyl- N 2 -formyl-5-methoxykynuramine (AFMK) . Journal of Pineal Research 45:3, pages 297-301.
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Tobias W. Fischer, Andrzej Slominski, Michal A. Zmijewski, Russel J. Reiter & Ralf Paus. (2008) Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Experimental Dermatology 17:9, pages 713-730.
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Miguel Cervantes, Gabriela Moral & Graciela Letechipa-Vallejo. (2008) Melatonin and ischemiareperfusion injury of the brain. Journal of Pineal Research 45:1, pages 1-7.
Crossref
Mandava V. Rao & Bindu Gangadharan. (2008) Antioxidative potential of melatonin against mercury induced intoxication in spermatozoa in vitro. Toxicology in Vitro 22:4, pages 935-942.
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Katinka Seever & Rüdiger Hardeland. (2008) Novel pathway for N 1 -acetyl-5-methoxykynuramine: UVB-induced liberation of carbon monoxide from precursor N 1 -acetyl-N 2 -formyl-5-methoxykynuramine . Journal of Pineal Research 44:4, pages 450-455.
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Valdecir F. Ximenes, Ana Paula Rodrigues, Cláudio Cabello, Manoel L. de Menezes & João Roberto Fernandes. (2008) The co-catalytic effect of chlorpromazine on peroxidase-mediated oxidation of melatonin: enhanced production of N 1 -acetyl-N 2 -formyl-5-methoxykynuramine . Journal of Pineal Research 44:2, pages 115-120.
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Mirko Krotzky & Rüdiger Hardeland. (2008) Metabolism of the Melatonin Metabolite N1-Acetyl-N2-formyl-5-methoxykynuramine in Saccharomyces cerevisiae. CYTOLOGIA 73:2, pages 123-128.
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Deepa S. Maharaj, Beverley D. Glass & Santy Daya. (2007) Melatonin: New Places in Therapy. Bioscience Reports 27:6, pages 299-320.
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Rüdiger Hardeland, Claudia Backhaus & Azadeh Fadavi. (2007) Reactions of the NO redox forms NO + , ? NO and HNO (protonated NO ? ) with the melatonin metabolite N 1 -acetyl-5-methoxykynuramine . Journal of Pineal Research 43:4, pages 382-388.
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Maria J. Perez, Beatriz Castaño, Jose M. Gonzalez-Buitrago & Jose J. G. Marin. (2007) Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver?placenta?maternal liver trio. Journal of Pineal Research 43:2, pages 130-139.
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Javier Gutierrez-Cuesta, Francesc X. Sureda, Marta Romeu, Anna M. Canudas, Beatriz Caballero, Ana Coto-Montes, Antoni Camins & Mercè Pallàs. (2007) Chronic administration of melatonin reduces cerebral injury biomarkers in SAMP8. Journal of Pineal Research 42:4, pages 394-402.
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Valdecir F. Ximenes, João Roberto Fernandes, Vânia B. Bueno, Luiz H. Catalani, Georgino H. de Oliveira & Rosângela G. P. Machado. (2007) The effect of pH on horseradish peroxidase-catalyzed oxidation of melatonin: production of N 1 -acetyl-N 2 -formyl-5-methoxykynuramine versus radical-mediated degradation . Journal of Pineal Research 42:3, pages 291-296.
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Sonja Riediger, Andreas Behrends, Björn Croll, Ignacio Vega‐Naredo, Nils Hänig, Burkhard Poeggeler, Jutta Böker, Sascha Grube, Juliane Gipp, Ana Coto‐Montes, Chandana Haldar & Rüdiger Hardeland. (2007) Toxicity of the quinalphos metabolite 2‐hydroxyquinoxaline: Growth inhibition, induction of oxidative stress, and genotoxicity in test organisms. Environmental Toxicology 22:1, pages 33-43.
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Dun-Xian Tan, Lucien C. Manchester, Maria P. Terron, Luis J. Flores & Russel J. Reiter. (2007) One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?. Journal of Pineal Research 42:1, pages 28-42.
Crossref
Sibel Süzen. 2007. Bioactive Heterocycles V. Bioactive Heterocycles V 145 178 .
V Srinivasan, SR Pandi-Perumal, DP Cardinali, B Poeggeler & R Hardeland. (2006) Melatonin in Alzheimer's disease and other neurodegenerative disorders. Behavioral and Brain Functions 2:1.
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Qiuhong Duan, Zhongqiang Wang, Tao Lu, Juan Chen & Ximing Wang. (2006) Comparison of 6-hydroxylmelatonin or melatonin in protecting neurons against ischemia/reperfusion-mediated injury. Journal of Pineal Research 41:4, pages 351-357.
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Margarita H. Guajardo, Ana M. Terrasa & Angel Catala. (2006) Lipid–protein modifications during ascorbate-Fe2+ peroxidation of photoreceptor membranes: protective effect of melatonin. Journal of Pineal Research 41:3, pages 201-210.
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C. F. Reyes-Toso, I. R. Rebagliati, C. R. Ricci, L. M. Linares, L. E. Albornoz, D. P. Cardinali & A. Zaninovich. (2006) Effect of melatonin treatment on oxygen consumption by rat liver mitochondria. Amino Acids 31:3, pages 299-302.
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Josefa León, Germaine Escames, María I. Rodríguez, Luis C. López, Víctor Tapias, Antonio Entrena, Encarnación Camacho, María D. Carrión, Miguel A. Gallo, Antonio Espinosa, Dun-Xian Tan, Russel J. Reiter & Darío Acuña-Castroviejo. (2006) Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin. Journal of Neurochemistry 98:6, pages 2023-2033.
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C. F. Reyes-Toso, L. M. Linares, L. E. Albornoz, D. Obaya-Naredo, M. L. Wallinger, C. R. Ricci & D. P. Cardinali. (2006) Comparative effects of melatonin and vitamin E in restoring aortic relaxation in pancreatectomized ratsEfectos comparativos de la melatonina y la vitamina E en la respuesta relajante de anillos aórticos de ratas pancreatectomizadas. Journal of Physiology and Biochemistry 62:3, pages 207-212.
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S. R. Pandi‐Perumal, V. Srinivasan, G. J. M. Maestroni, D. P. Cardinali, B. Poeggeler & R. Hardeland. (2006) Melatonin. The FEBS Journal 273:13, pages 2813-2838.
Crossref
Tobias W. Fischer, Trevor W. Sweatman, Igor Semak, Robert M. Sayre, Jacobo Wortsman, Andrƶej Slominski, Tobias W. Fischer, Trevor W. Sweatman, Igor Semak, Robert M. Sayre, Jacobo Wortsman & Andrzej Slominski. (2006) Constitutive and UV‐induced metabolism of melatonin in keratinocytes and cell‐free systems. The FASEB Journal 20:9, pages 1564-1566.
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Mahmoud R. Hussein, Eman E. Abu-Dief, Amal T. Abou El-Ghait, Mohamed A. Adly & Mohamad H. Abdelraheem. (2006) Morphological evaluation of the radioprotective effects of melatonin against X-ray-induced early and acute testis damage in Albino rats: an animal model. International Journal of Experimental Pathology 87:3, pages 237-250.
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Xiaochao Ma, Jeffrey R. Idle, Kristopher W. Krausz, Dun-Xian Tan, Leopoldo Ceraulo & Frank J. Gonzalez. (2006) Urinary metabolites and antioxidant products of exogenous melatonin in the mouse. Journal of Pineal Research 40:4, pages 343-349.
Crossref
Marta G. Ladizesky, Verónica Boggio, Rodolfo A. Cutrera, Nélida Mondelo, Silvina Mastaglia, Julia Somoza & Daniel P. Cardinali. (2006) Melatonin effect on bone metabolism in rats treated with methylprednisolone. Journal of Pineal Research 40:4, pages 297-304.
Crossref
Yuan-Hua Chen, De-Xiang Xu, Jian-Ping Wang, Hua Wang, Ling-Zhen Wei, Mei-Fang Sun & Wei Wei. (2006) Melatonin protects against lipopolysaccharide-induced intra-uterine fetal death and growth retardation in mice. Journal of Pineal Research 40:1, pages 40-47.
Crossref
Rüdiger Hardeland & SR Pandi-Perumal. (2005) Melatonin, a potent agent in antioxidative defense: Actions as a natural food constituent, gastrointestinal factor, drug and prodrug. Nutrition & Metabolism 2:1.
Crossref
S.R. Pandi-Perumal, N. Zisapel, V. Srinivasan & D.P. Cardinali. (2005) Melatonin and sleep in aging population. Experimental Gerontology 40:12, pages 911-925.
Crossref
V. Srinivasan, S. R. Pandi-Perumal, G. J. M. Maestroni, A. I. Esquifino, R. Hardeland & D. P. Cardinali. (2005) Role of melatonin in neurodegenerative diseases. Neurotoxicity Research 7:4, pages 293-318.
Crossref
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Edward Ram, Tali H Vishne, Talia Weinstein, Benzion Beilin & Zeev Dreznik. (2005) General Anesthesia for Surgery Influences Melatonin and Cortisol Levels. World Journal of Surgery 29:7, pages 826-829.
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S.O. Silva, M.R. Rodrigues, V.F. Ximenes, A.E.B. Bueno-da-Silva, G.P. Amarante-Mendes & A. Campa. (2004) Neutrophils as a specific target for melatonin and kynuramines: effects on cytokine release. Journal of Neuroimmunology 156:1-2, pages 146-152.
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Sueli O. Silva, Maria R. Rodrigues, Sandra R. Q. Carvalho, Luiz H. Catalani, Ana Campa & Valdecir F. Ximenes. (2004) Oxidation of melatonin and its catabolites, N1-acetyl-N 2-formyl-5-methoxykynuramine and N1-acetyl-5-methoxykynuramine, by activated leukocytes. Journal of Pineal Research 37:3, pages 171-175.
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