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Original Articles

Safety of artemisinins during early pregnancy, assessed in 62 Sudanese women

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Pages 205-210 | Published online: 18 Jul 2013

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Read on this site (7)

Makoto Saito, Mary Ellen Gilder, Rose McGready & François Nosten. (2018) Antimalarial drugs for treating and preventing malaria in pregnant and lactating women. Expert Opinion on Drug Safety 17:11, pages 1129-1144.
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Harry Tagbor, Gifty Antwi & Joslin Dogbe. (2014) Safety of antimalarial drugs exposure during early pregnancy. Research and Reports in Tropical Medicine 5, pages 23-33.
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Benjamin J Visser, Michèle van Vugt & Martin P Grobusch. (2014) Malaria: an update on current chemotherapy. Expert Opinion on Pharmacotherapy 15:15, pages 2219-2254.
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Brian Angus. (2014) Novel anti-malarial combinations and their toxicity. Expert Review of Clinical Pharmacology 7:3, pages 299-316.
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Theonest K Mutabingwa & Ishag Adam. (2013) Use of artemether–lumefantrine to treat malaria during pregnancy: what do we know and need to know?. Expert Review of Anti-infective Therapy 11:2, pages 125-135.
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Kamal Hamed & Heiner Grueninger. (2012) Coartem®: a decade of patient-centric malaria management. Expert Review of Anti-infective Therapy 10:6, pages 645-659.
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Pauline Byakika-Kibwika, Mohammed Lamorde, Harriet Mayanja-Kizza, Concepta Merry, Bob Colebunders & Jean-Pierre Van geertruyden. (2010) Update on the efficacy, effectiveness and safety of artemether–lumefantrine combination therapy for treatment of uncomplicated malaria. Therapeutics and Clinical Risk Management 6, pages 11-20.
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Articles from other publishers (24)

Robert L. Clark. (2022) Safety of treating malaria with artemisinin-based combination therapy in the first trimester of pregnancy. Reproductive Toxicology 111, pages 204-210.
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Robert L. Clark. (2020) Teratogen update: Malaria in pregnancy and the use of antimalarial drugs in the first trimester. Birth Defects Research 112:18, pages 1403-1449.
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Sarah D’Alessandro, Elena Menegola, Silvia Parapini, Donatella Taramelli & Nicoletta Basilico. (2020) Safety of Artemisinin Derivatives in the First Trimester of Pregnancy: A Controversial Story. Molecules 25:15, pages 3505.
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Robert L. Clark, Tammye L. Edwards, Monica Longo, Joseph Kinney, Don K. Walker, Jon Rhodes, Sally A. Clode, Thomas Rückle, Timothy Wells, Nicole Andenmatten & Anna Christine Huber. (2018) Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate. Birth Defects Research 110:7, pages 553-578.
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Robert L. Clark. (2017) Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester. Birth Defects Research 109:14, pages 1075-1126.
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Chinaka O. Nwaehujor, Onyeka V. Asuzu, Daniel D. Nwibo, Obichukwu C. Nwobi & Ihechiluru I. Ezeigbo. (2017) Effects of Artesunate on some biochemical parameters in pregnant albino Wistar rats challenged with lethal strain Plasmodium berghei NK65: Appreciating the activities of artemisinin drugs on key pregnancy hormone balance. Experimental and Toxicologic Pathology 69:6, pages 408-411.
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Caroline Gomes, Ana Cláudia Boareto & Paulo Roberto Dalsenter. (2016) Clinical and non-clinical safety of artemisinin derivatives in pregnancy. Reproductive Toxicology 65, pages 194-203.
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Kerryn A Moore, Julie A Simpson, Moo Kho Paw, MuPawJay Pimanpanarak, Jacher Wiladphaingern, Marcus J Rijken, Podjanee Jittamala, Nicholas J White, Freya J I Fowkes, François Nosten & Rose McGready. (2016) Safety of artemisinins in first trimester of prospectively followed pregnancies: an observational study. The Lancet Infectious Diseases 16:5, pages 576-583.
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Halidou Tinto, Esperança Sevene, Stephanie Dellicour, Gregory S. Calip, Umberto d’Alessandro, Eusébio Macete, Seydou Nakanabo-Diallo, Adama Kazienga, Innocent Valea, Hermann Sorgho, Anifa Valá, Orvalho Augusto, Maria Ruperez, Clara Menendez, Peter Ouma, Meghna Desai, Feiko Ter Kuile & Andy Stergachis. (2015) Assessment of the safety of antimalarial drug use during early pregnancy (ASAP): protocol for a multicenter prospective cohort study in Burkina Faso, Kenya and Mozambique. Reproductive Health 12:1.
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Stephanie Dellicour, Meghna Desai, George Aol, Martina Oneko, Peter Ouma, Godfrey Bigogo, Deron C. Burton, Robert F. Breiman, Mary J. Hamel, Laurence Slutsker, Daniel Feikin, Simon Kariuki, Frank Odhiambo, Jayesh Pandit, Kayla F. Laserson, Greg Calip, Andy Stergachis & Feiko O. ter Kuile. (2015) Risks of miscarriage and inadvertent exposure to artemisinin derivatives in the first trimester of pregnancy: a prospective cohort study in western Kenya. Malaria Journal 14:1.
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Stephanie Padberg. 2015. Drugs During Pregnancy and Lactation. Drugs During Pregnancy and Lactation 115 176 .
Dominic Mosha, Festo Mazuguni, Sigilbert Mrema, Esperanca Sevene, Salim Abdulla & Blaise Genton. (2014) Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort. Malaria Journal 13:1.
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Dominic Mosha, Festo Mazuguni, Sigilbert Mrema, Salim Abdulla & Blaise Genton. (2014) Medication exposure during pregnancy: a pilot pharmacovigilance system using health and demographic surveillance platform. BMC Pregnancy and Childbirth 14:1.
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Xiao-rong Deng, Zhao-xia Liu, Feng Liu, Lei Pan, He-ping Yu, Jin-ping Jiang, Jian-jun Zhang, Li Liu & Jun Yu. (2013) Holotransferrin enhances selective anticancer activity of artemisinin against human hepatocellular carcinoma cells. Journal of Huazhong University of Science and Technology [Medical Sciences] 33:6, pages 862-865.
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Stephen Rulisa, Nadine Kaligirwa, Steven Agaba, Corine Karema, Petra F Mens & Peter J de Vries. (2012) Pharmacovigilance of artemether-lumefantrine in pregnant women followed until delivery in Rwanda. Malaria Journal 11:1.
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Christine Manyando, Kassoum Kayentao, Umberto D’Alessandro, Henrietta U Okafor, Elizabeth Juma & Kamal Hamed. (2012) A systematic review of the safety and efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria during pregnancy. Malaria Journal 11:1.
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R McGready, SJ Lee, J Wiladphaingern, EA Ashley, MJ Rijken, M Boel, JA Simpson, MK Paw, M Pimanpanarak, Oh Mu, P Singhasivanon, NJ White & FH Nosten. (2012) Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: a population-based study. The Lancet Infectious Diseases 12:5, pages 388-396.
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Yves Carlier, Carine Truyens, Philippe Deloron & François Peyron. (2012) Congenital parasitic infections: A review. Acta Tropica 121:2, pages 55-70.
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Robert L. Clark. (2011) Effects of artemisinins on reticulocyte count and relationship to possible embryotoxicity in confirmed and unconfirmed malarial patients. Birth Defects Research Part A: Clinical and Molecular Teratology 94:2, pages 61-75.
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Gilbert Lefèvre, Anne Claire Marrast & Heiner Grueninger. (2011) Novartis Malaria Initiative: best practice example of pharmaceutical industry's engagement in the fight against malaria. Annals of the New York Academy of Sciences 1222:1, pages 19-29.
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Oscar Ozmund Simooya. 2011. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 567 576 .
Rose McGready & François Nosten. (2010) Which drug is effective and safe for acute malaria in pregnancy? Reviewing the evidence. Drug Development Research 71:1, pages 56-68.
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Qigui Li & Peter Weina. (2009) Severe Embryotoxicity of Artemisinin Derivatives in Experimental Animals, but Possibly Safe in Pregnant Women. Molecules 15:1, pages 40-57.
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Gamal K. Adam, Mohamed A. Abdulla, Ahmed A. Ahmed & Ishag Adam. (2009) Maternal and perinatal outcomes of visceral leishmaniasis (kala-azar) treated with sodium stibogluconate in eastern Sudan. International Journal of Gynecology & Obstetrics 107:3, pages 208-210.
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