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Prisca Baah Nketia, Edward Ntim Gasu, Jehoshaphat Oppong Mensah & Lawrence Sheringham Borquaye. (2023) In silico identification of α-bisabolol and letestuianin C as potential inhibitors of Trypanosoma brucei trypanothione reductase. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-13.
Read now
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Rahma Muhammad Adamu, Bashiru Ibrahim, Mohammed Auwal Ibrahim & Emmanuel Oluwadare Balogun. (2023) Identification of megacerotonic acid and a quinazoline derivative from Universal Natural Product Database as potential inhibitors of Trypanosoma brucei brucei alternative oxidase: molecular docking, molecular dynamic simulation and MM/PBSA analysis. Journal of Biomolecular Structure and Dynamics 41:1, pages 45-54.
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Geofrey Omarch, Yunus Kippie, Shireen Mentor, Naushaad Ebrahim, David Fisher, Grace Murilla, Hulda Swai & Admire Dube. (2019) Comparative in vitro transportation of pentamidine across the blood-brain barrier using polycaprolactone nanoparticles and phosphatidylcholine liposomes. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 1428-1436.
Read now
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Adrienne J Showler, Mary E Wilson, Kevin C Kain & Andrea K Boggild. (2014) Parasitic diseases in travelers: a focus on therapy. Expert Review of Anti-infective Therapy 12:4, pages 497-521.
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Articles from other publishers (165)
Nnamdi Ikeogu, Folayemi Olayinka-Adefemi, Chidalu Edechi, Chukwunonso Onyilagha, Ping Jia, Aaron Marshall, Julius Ode & Jude Uzonna. (2023) Crosspteryx fibrifuga leaf extract enhances host resistance to Trypanosoma congolense infection in mice by regulating host immune response and disrupting the activity of parasite superoxide dismutase enzyme. Frontiers in Microbiology 14.
Crossref
Crossref
Guerisson Bairy, Cyrille Oliver Ozzin-Kholy Zolipou & Romaric Nzoumbou-Boko. (2023) In vitro trypanocidal activity of extracts and compounds isolated from Vitellaria paradoxa. BMC Complementary Medicine and Therapies 23:1.
Crossref
Crossref
Anna Seetsi, David D. N'da, Nthatisi Molefe‐Nyembe, Keisuke Suganuma, Tsepo Ramatla & Oriel Thekisoe. (2023)
In vitro anti‐trypanosomal activity of synthetic nitrofurantoin‐triazole hybrids against
Trypanosoma
species causing human African trypanosomosis
. Fundamental & Clinical Pharmacology.
Crossref
Crossref
Aditi Mukherjee, Zakir Hossain, Esteban Erben, Shuai Ma, Jun Yong Choi & Hee-Sook Kim. (2023) Identification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1. Nature Communications 14:1.
Crossref
Crossref
Faiza Bano, Ibadullah Jan, Aayesha Riaz, Tariq Hussain, Onur Ceylan, Ceylan Ceylan & Muhammad Zeeshan. 2023. Parasitism and Parasitic Control in Animals. Parasitism and Parasitic Control in Animals
90
110
.
Christopher P. Watson, Gayathri Nair Sekhar & Sarah A. Thomas. (2023) Identification of transport systems involved in eflornithine delivery across the blood-brain barrier. Frontiers in Drug Delivery 3.
Crossref
Crossref
Martin Rivara-Espasandín, Miranda Clara Palumbo, Ezequiel J. Sosa, Santiago Radío, Adrián G. Turjanski, José Sotelo-Silveira, Dario Fernandez Do Porto & Pablo Smircich. (2023) Omics data integration facilitates target selection for new antiparasitic drugs against TriTryp infections. Frontiers in Pharmacology 14.
Crossref
Crossref
Carlos García-Estrada, Yolanda Pérez-Pertejo, Bárbara Domínguez-Asenjo, Vanderlan Nogueira Holanda, Sankaranarayanan Murugesan, María Martínez-Valladares, Rafael Balaña-Fouce & Rosa M. Reguera. (2023) Further Investigations of Nitroheterocyclic Compounds as Potential Antikinetoplastid Drug Candidates. Biomolecules 13:4, pages 637.
Crossref
Crossref
Victor Kande Betu Kumeso, Wilfried Mutombo Kalonji, Sandra Rembry, Olaf Valverde Mordt, Digas Ngolo Tete, Adeline Prêtre, Sophie Delhomme, Médard Ilunga Wa Kyhi, Mamadou Camara, Julie Catusse, Stefan Schneitter, Morgane Nusbaumer, Erick Mwamba Miaka, Hélène Mahenzi Mbembo, Joseph Makaya Mayawula, Mariame Layba Camara, Félix Akwaso Massa, Lewis Kaninda Badibabi, Augustin Kasongo Bonama, Papy Kavunga Lukula, Sylvain Mutanda Kalonji, Phyll Mariero Philemon, Ricardo Mokilifi Nganyonyi, Hugues Embana Mankiara, André Asuka Akongo Nguba, Vincent Kobo Muanza, Ernest Mulenge Nasandhel, Aimée Fifi Nzeza Bambuwu, Bruno Scherrer, Nathalie Strub-Wourgaft & Antoine Tarral. (2023) Efficacy and safety of acoziborole in patients with human African trypanosomiasis caused by Trypanosoma brucei gambiense: a multicentre, open-label, single-arm, phase 2/3 trial. The Lancet Infectious Diseases 23:4, pages 463-470.
Crossref
Crossref
Kingsley Onyekachi Moh, Sodangi Abdulkarim Luka, Iliya Shehu Ndams, Idris Alao Lawal, Dahiru Sani, Sylvester Sunday Obeta, Gbenga Peter Oderinde, Emeka John Dingwoke, Fatima Amin Adamude, Abraham Ehinomhen Ubhenin & Saifullahi Umar. (2023) Molecular and phylogenetic analysis of a type K1 strain Trypanosoma evansi isolate from Nigerian cattle: An evaluation of the therapeutic effects of compounds from Brassica oleracea on the histopathology of infected wister rats. Biochemistry and Biophysics Reports 33, pages 101424.
Crossref
Crossref
Naila Zaman & Syed Sikander Azam. (2023) Quantum Dynamics and Bi Metal Force Field Parameterization Yielding Significant Antileishmanial Targets. Journal of Chemical Information and Modeling 63:4, pages 1371-1385.
Crossref
Crossref
Kaori Oda, Satoshi Miyamoto, Ryo Kodera, Jun Wada & Kenichi Shikata. (2022)
Suramin prevents the development of diabetic kidney disease by inhibiting
NLRP3
inflammasome activation in
KK‐Ay
mice
. Journal of Diabetes Investigation 14:2, pages 205-220.
Crossref
Crossref
Karol R. Francisco, Ludovica Monti, Wenqian Yang, Hayoung Park, Lawrence J. Liu, Kaitlyn Watkins, Dilini K. Amarasinghe, Marianna Nalli, Carlos Roberto Polaquini, Luis O. Regasini, Antônio Eduardo Miller Crotti, Romano Silvestri, Lizandra Guidi Magalhães & Conor R. Caffrey. (2023) Structure-activity relationship of dibenzylideneacetone analogs against the neglected disease pathogen, Trypanosoma brucei. Bioorganic & Medicinal Chemistry Letters 81, pages 129123.
Crossref
Crossref
Ritu Tomar, Rahul Tiwari, Rupa Gupta, Samir Bhargava, Dheeraj Bisht, Vijay Singh Rana & Neeraj Kumar Sethiya. 2023. Natural Products in Vector-Borne Disease Management. Natural Products in Vector-Borne Disease Management
379
411
.
Kushneet Kaur Sodhi, Pallee Shree, Lokesh Chandra Mishra, Gauri Mishra, Mohit Kumar & Dileep K. Singh. 2023. Natural Product Based Drug Discovery Against Human Parasites. Natural Product Based Drug Discovery Against Human Parasites
411
429
.
Kedar S. Prayag & Anil B. Jindal. 2023. Nanomedicines for the Prevention and Treatment of Infectious Diseases. Nanomedicines for the Prevention and Treatment of Infectious Diseases
239
263
.
D. V. Danilov, V. S. D’yachenko, V. V. Burmistrov & G. M. Butov. (2022) Synthesis and Properties of 1,3-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: XVI. Synthesis and Properties of 1,1'-(Alkane-1,n-diyl)bis{3-[(3,5-dimethyladamantan-1-yl)methyl]ureas}. Russian Journal of Organic Chemistry 58:11, pages 1561-1568.
Crossref
Crossref
Keneth Iceland Kasozi, Ewan Thomas MacLeod & Susan Christina Welburn. (2022) Systematic Review and Meta-Analysis on Human African Trypanocide Resistance. Pathogens 11:10, pages 1100.
Crossref
Crossref
Sudhakar Reddy Kalluri, Rajneesh Srivastava, Selin Kenet, Goutam K. Tanti, Klaus Dornmair, Jeffrey L. Bennett, Thomas Misgeld, Bernhard Hemmer, Matthias T. Wyss & Marina Herwerth. (2022) P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica. Neurotherapeutics 19:5, pages 1603-1616.
Crossref
Crossref
Julianne Meisner, Agapitus Kato, Marshal Msanyama Lemerani, Erick Mwamba Miaka, Acaga Ismail Taban, Jonathan Wakefield, Ali Rowhani-Rahbar, David M. Pigott, Jonathan D. Mayer & Peter M. Rabinowitz. (2022) The effect of livestock density on Trypanosoma brucei gambiense and T. b. rhodesiense: A causal inference-based approach. PLOS Neglected Tropical Diseases 16:8, pages e0010155.
Crossref
Crossref
Fabio Marchetti, Alessia Tombesi, Corrado Di Nicola, Riccardo Pettinari, Federico Verdicchio, Alessandra Crispini, Francesca Scarpelli, Cecilia Baldassarri, Elisa Marangoni, Anders Hofer, Agustín Galindo & Riccardo Petrelli. (2022)
Zinc(II) Complex with Pyrazolone-Based Hydrazones is Strongly Effective against
Trypanosoma brucei
Which Causes African Sleeping Sickness
. Inorganic Chemistry 61:34, pages 13561-13575.
Crossref
Crossref
Dorien Mabille, Kayhan Ilbeigi, Sarah Hendrickx, Marzuq A. Ungogo, Fabian Hulpia, Cai Lin, Louis Maes, Harry P. de Koning, Serge Van Calenbergh & Guy Caljon. (2022) Nucleoside analogues for the treatment of animal trypanosomiasis. International Journal for Parasitology: Drugs and Drug Resistance 19, pages 21-30.
Crossref
Crossref
Santo Previti, Roberta Ettari, Elsa Calcaterra, Carla Di Chio, Rahul Ravichandran, Collin Zimmer, Stefan Hammerschmidt, Annika Wagner, Marta Bogacz, Sandro Cosconati, Tanja Schirmeister & Maria Zappalà. (2022) Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain. ACS Medicinal Chemistry Letters 13:7, pages 1083-1090.
Crossref
Crossref
Alberto Venturelli, Lorenzo Tagliazucchi, Clara Lima, Federica Venuti, Giulia Malpezzi, George E. Magoulas, Nuno Santarem, Theodora Calogeropoulou, Anabela Cordeiro-da-Silva & Maria Paola Costi. (2022) Current Treatments to Control African Trypanosomiasis and One Health Perspective. Microorganisms 10:7, pages 1298.
Crossref
Crossref
Santo Previti, Roberta Ettari, Carla Di Chio, Rahul Ravichandran, Marta Bogacz, Ute A. Hellmich, Tanja Schirmeister, Sandro Cosconati & Maria Zappalà. (2022) Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis. Molecules 27:12, pages 3765.
Crossref
Crossref
Carla Di Chio, Santo Previti, Giorgio Amendola, Rahul Ravichandran, Annika Wagner, Sandro Cosconati, Ute A. Hellmich, Tanja Schirmeister, Maria Zappalà & Roberta Ettari. (2022) Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense. European Journal of Medicinal Chemistry 236, pages 114328.
Crossref
Crossref
Matilde Ortiz-Gonzalez, Ignacio Pérez-Victoria, Inmaculada Ramirez-Macias, Nuria de Pedro, Angel Linde-Rodriguez, Víctor González-Menéndez, Victoria Sanchez-Martin, Jesús Martín, Ana Soriano-Lerma, Olga Genilloud, Virginia Perez-Carrasco, Francisca Vicente, José Maceira, Carlos A. Rodrígues-Poveda, José María Navarro-Marí, Fernando Reyes, Miguel Soriano & Jose A. Garcia-Salcedo. (2022) Curvicollide D Isolated from the Fungus Amesia sp. Kills African Trypanosomes by Inhibiting Transcription. International Journal of Molecular Sciences 23:11, pages 6107.
Crossref
Crossref
Nicola S. Carter, Yumena Kawasaki, Surbhi S. Nahata, Samira Elikaee, Sara Rajab, Leena Salam, Mohammed Y. Alabdulal, Kelli K. Broessel, Forogh Foroghi, Alyaa Abbas, Reyhaneh Poormohamadian & Sigrid C. Roberts. (2022) Polyamine Metabolism in Leishmania Parasites: A Promising Therapeutic Target. Medical Sciences 10:2, pages 24.
Crossref
Crossref
Fernando Altamura, Rishi Rajesh, Carolina M. C. Catta‐Preta, Nilmar S. Moretti & Igor Cestari. (2020) The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets. Drug Development Research 83:2, pages 225-252.
Crossref
Crossref
Yasmin Pedra-Rezende, Isabela S. Macedo, Victor Midlej, Rafael M. Mariante & Rubem F. S. Menna-Barreto. (2022) Different Drugs, Same End: Ultrastructural Hallmarks of Autophagy in Pathogenic Protozoa. Frontiers in Microbiology 13.
Crossref
Crossref
Keneth Iceland Kasozi, Ewan Thomas MacLeod, Ibrahim Ntulume & Susan Christina Welburn. (2022) An Update on African Trypanocide Pharmaceutics and Resistance. Frontiers in Veterinary Science 9.
Crossref
Crossref
Gete Chemeda, Daniel Bisrat, Mariamawit Y. Yeshak & Kaleab Asres. (2022) In Vitro Antileishmanial and Antitrypanosomal Activities of Plicataloside Isolated from the Leaf Latex of Aloe rugosifolia Gilbert & Sebsebe (Asphodelaceae). Molecules 27:4, pages 1400.
Crossref
Crossref
Paulo A. F. Pacheco & Maria M. M. Santos. (2022) Recent Progress in the Development of Indole-Based Compounds Active against Malaria, Trypanosomiasis and Leishmaniasis. Molecules 27:1, pages 319.
Crossref
Crossref
Nuzhat Parveen, Yan-Liang Lin, Ruey-Hwang Chou, Chung-Ming Sun & Chin Yu. (2022) Synthesis of Novel Suramin Analogs With Anti-Proliferative Activity via FGF1 and FGFRD2 Blockade. Frontiers in Chemistry 9.
Crossref
Crossref
Klaudia T. Angula, Lesetja J. Legoabe, Tarryn Swart, Heinrich C. Hoppe & Richard M. Beteck. (2022) Synthesis and in vitro antitrypanosomal evaluation of novel 6-heteroarylidene-substituted quinolone derivatives. European Journal of Medicinal Chemistry 227, pages 113913.
Crossref
Crossref
Wessal Hanout & Nir Qvit. 2022. Peptide and Peptidomimetic Therapeutics. Peptide and Peptidomimetic Therapeutics
371
415
.
Rashika El Ridi. 2022. Encyclopedia of Infection and Immunity. Encyclopedia of Infection and Immunity
510
529
.
Joshua B. Benoit, Geoffrey M. Attardo & Brian L. Weiss. 2022. Encyclopedia of Infection and Immunity. Encyclopedia of Infection and Immunity
837
851
.
Mengqiao Li, Stefan Gaussmann, Bettina Tippler, Julia Ott, Grzegorz M Popowicz, Wolfgang Schliebs, Michael Sattler, Ralf Erdmann & Vishal C Kalel. (2021) Novel Trypanocidal Inhibitors that Block Glycosome Biogenesis by Targeting PEX3–PEX19 Interaction. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Danica R. Cullen, Ashlee Gallagher, Caitlin L. Duncan, Jutharat Pengon, Roonglawan Rattanajak, Jason Chaplin, Hendra Gunosewoyo, Sumalee Kamchonwongpaisan, Alan Payne & Mauro Mocerino. (2021) Synthesis and evaluation of tetrahydroisoquinoline derivatives against Trypanosoma brucei rhodesiense. European Journal of Medicinal Chemistry 226, pages 113861.
Crossref
Crossref
Juan Güiza, Javiera Arriagada, Luis Rodríguez, Camila Gutiérrez, Yorley Duarte, Juan C. Sáez & José L. Vega. (2021) Anti-parasitic drugs modulate the non-selective channels formed by connexins or pannexins. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867:10, pages 166188.
Crossref
Crossref
Renan Augusto Gomes, Evelin Fornari, Ana Carolina Silva Rocha, Gustavo Luis Tripodi, Flavio da Silva Emery & Gustavo Henrique Goulart Trossini. (2021) Parasitic sirtuin 2 as an opportunity in drug discovery. Future Medicinal Chemistry 13:16, pages 1397-1409.
Crossref
Crossref
Rian Snijders, Alain Fukinsia, Yves Claeys, Epco Hasker, Alain Mpanya, Erick Miaka, Filip Meheus & Marleen Boelaert. (2021) Costs and Outcomes of Integrated Human African Trypanosomiasis Surveillance System Using Rapid Diagnostic Tests, Democratic Republic of the Congo. Emerging Infectious Diseases 27:8, pages 2144-2153.
Crossref
Crossref
Ambika Dattani, Isatou Drammeh, Aishah Mahmood, Mahbubur Rahman, Joanna Szular & Shane R. Wilkinson. (2021) Unraveling the antitrypanosomal mechanism of benznidazole and related 2‐nitroimidazoles: From prodrug activation to DNA damage. Molecular Microbiology 116:2, pages 674-689.
Crossref
Crossref
Omobolanle J. Jesumoroti, Richard M. Beteck & Lesetja J. Legoabe. (2021) In-vitro Anti-trypanosomal and Cytotoxicity Evaluation of
3-methyl-3,4-dihydroquinazolin-2(1H)-one Derivatives. Drug Research 71:06, pages 335-340.
Crossref
Crossref
Victor Kande Betu Ku Mesu, Wilfried Mutombo Kalonji, Clélia Bardonneau, Olaf Valverde Mordt, Digas Ngolo Tete, Séverine Blesson, François Simon, Sophie Delhomme, Sonja Bernhard, Hélène Mahenzi Mbembo, Christian Mpia Moke, Steven Lumeya Vuvu, Junior Mudji E'kitiak, Felix Akwaso Masa, Melchias Mukendi Ilunga, Dieudonné Mpoyi Muamba Nzambi, Tim Mayala Malu, Serge Kapongo Tshilumbwa, Franck Botalema Bolengi, Mathieu Nkieri Matsho, Crispin Lumbala, Bruno Scherrer, Nathalie Strub-Wourgaft & Antoine Tarral. (2021) Oral fexinidazole for stage 1 or early stage 2 African Trypanosoma brucei gambiense trypanosomiasis: a prospective, multicentre, open-label, cohort study. The Lancet Global Health 9:7, pages e999-e1008.
Crossref
Crossref
Walter O. Okello, Christine A. Amongi, Dennis Muhanguzi, Ewan T. MacLeod, Charles Waiswa, Alexandra P. Shaw & Susan C. Welburn. (2021) Livestock Network Analysis for Rhodesiense Human African Trypanosomiasis Control in Uganda. Frontiers in Veterinary Science 8.
Crossref
Crossref
Breanna Walsh & Kent L. Hill. (2021)
Right place, right time: Environmental sensing and signal transduction directs cellular differentiation and motility in
Trypanosoma brucei
. Molecular Microbiology 115:5, pages 930-941.
Crossref
Crossref
Albandary Almahri & Mohamed A. Abdel-Lateef. (2021) Application of Hantzsch reaction for sensitive determination of eflornithine in cream, plasma and urine samples. Royal Society Open Science 8:5.
Crossref
Crossref
Napoleon A. Mfonku, Alain T. Tadjong, Gabriel T. Kamsu, Norbert Kodjio, Jie Ren, James A. Mbah, Donatien Gatsing & Jixun Zhan. (2021) Isolation and characterization of antisalmonellal anthraquinones and coumarins from Morinda lucida Benth. (Rubiaceae). Chemical Papers 75:5, pages 2067-2073.
Crossref
Crossref
Donald J. AbrahamConor R. Caffrey, Dietmar Steverding, Rafaela S. Ferreira, Renata B. de Oliveira, Anthony J. O'Donoghue, Ludovica Monti, Carlo Ballatore, Kelly A. Bachovchin, Lori Ferrins, Michael P. Pollastri, Kimberley M. Zorn, Daniel H. Foil, Alex M. Clark, Melina Mottin, Carolina H. Andrade, Jair L. de Siqueira‐Neto & Sean Ekins. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery
1
79
.
Dorien Mabille, Camila Cardoso Santos, Rik Hendrickx, Mathieu Claes, Peter Takac, Christine Clayton, Sarah Hendrickx, Fabian Hulpia, Louis Maes, Serge Van Calenbergh & Guy Caljon. (2021) 4E Interacting Protein as a Potential Novel Drug Target for Nucleoside Analogues in Trypanosoma brucei. Microorganisms 9:4, pages 826.
Crossref
Crossref
Catherine N. Mutuku, Rosemary Bateta, Martin K. Rono, James M. Njunge, Erick O. Awuoche, Kariuki Ndung'u, Clarence M. Mang'era, Modesta O. Akoth, Vincent O. Adung'a, Bartholomew N. Ondigo & Paul O. Mireji. (2021) Physiological and proteomic profiles of Trypanosoma brucei rhodesiense parasite isolated from suramin responsive and non-responsive HAT patients in Busoga, Uganda. International Journal for Parasitology: Drugs and Drug Resistance 15, pages 57-67.
Crossref
Crossref
Fostino R. B. Bokosi, Richard M. Beteck, Dustin Laming, Heinrich C. Hoppe, Tendamudzimu Tshiwawa & Setshaba D. Khanye. (2021)
Synthesis of 2‐(
N
‐cyclicamino)quinoline combined with methyl (
E
)‐3‐(2/3/4‐aminophenyl)acrylates as potential antiparasitic agents
. Archiv der Pharmazie.
Crossref
Crossref
Brian Pérez, León A. Bouvier, Juan José Cazzulo, Fernán Agüero, Emir Salas-Sarduy & Vanina E. Alvarez. (2021) Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity. Antimicrobial Agents and Chemotherapy 65:3.
Crossref
Crossref
Vanina E. Alvarez, Paula A. Iribarren, Gabriela T. Niemirowicz & Juan José Cazzulo. (2021) Update on relevant trypanosome peptidases: Validated targets and future challenges. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1869:2, pages 140577.
Crossref
Crossref
Erik de Heuvel, Albert J. Kooistra, Ewald Edink, Sjors van Klaveren, Jeffrey Stuijt, Tiffany van der Meer, Payman Sadek, Dorien Mabille, Guy Caljon, Louis Maes, Marco Siderius, Iwan J. P. de Esch, Geert Jan Sterk & Rob Leurs. (2021) Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening. Frontiers in Chemistry 8.
Crossref
Crossref
Johan Zeelen, Monique van Straaten, Joseph Verdi, Alexander Hempelmann, Hamidreza Hashemi, Kathryn Perez, Philip D. Jeffrey, Silvan Hälg, Natalie Wiedemar, Pascal Mäser, F. Nina Papavasiliou & C. Erec Stebbins. (2021) Structure of trypanosome coat protein VSGsur and function in suramin resistance. Nature Microbiology 6:3, pages 392-400.
Crossref
Crossref
Tetsuya OKADA & Takashi INUI. (2021) Development of therapeutic agents for human African trypanosomiasis. Translational and Regulatory Sciences 3:2, pages 43-50.
Crossref
Crossref
Riti Mehta & Souvik Sengupta. 2021. Emerging Trends in Nanomedicine. Emerging Trends in Nanomedicine
203
234
.
Hafiz Muhammad Rizwan, Haider Abbas, Muhammad Sohail Sajid, Mahvish Maqbool, Malcolm K. Jones, Muhammad Irfan Ullah & Nabeel Ijaz. 2021. Biochemistry of Drug Resistance. Biochemistry of Drug Resistance
95
142
.
Ronald W. Brown, Ashraf M. Abdel-Megeed, Paul A. Keller, Amy J. Jones, Melissa L. Sykes, Marcel Kaiser, Jonathan B. Baell, Vicky M. Avery & Christopher J. T. Hyland. (2020) Investigation of thiazolyl–benzothiophenamides as potential agents for African sleeping sickness. RSC Medicinal Chemistry 11:12, pages 1413-1422.
Crossref
Crossref
Ahmed Aboelmagd, Saad H. Alotaibi, Samir M. El Rayes, Gomaa M. Elsayed, Ibrahim A. I. Ali, Walid Fathalla, Faheem H. Pottoo & Firdos A. Khan. (2020)
Synthesis and Anti proliferative Activity of New
N
‐Pentylquinoxaline carboxamides and Their
O
‐Regioisomer
. ChemistrySelect 5:43, pages 13439-13453.
Crossref
Crossref
Nuzhat Parveen, Yan-Liang Lin, Md Imran Khan, Ruey-Hwang Chou, Chung-Ming Sun & Chin Yu. (2020) Suramin derivatives play an important role in blocking the interaction between FGF1 and FGFRD2 to inhibit cell proliferation. European Journal of Medicinal Chemistry 206, pages 112656.
Crossref
Crossref
Jyoti Gahtori, Suyash Pant & Hemant Kumar Srivastava. (2019) Modeling antimalarial and antihuman African trypanosomiasis compounds: a ligand- and structure-based approaches. Molecular Diversity 24:4, pages 1107-1124.
Crossref
Crossref
Alexander I. Kostyuk, Anastasiya S. Panova, Aleksandra D. Kokova, Daria A. Kotova, Dmitry I. Maltsev, Oleg V. Podgorny, Vsevolod V. Belousov & Dmitry S. Bilan. (2020) In Vivo Imaging with Genetically Encoded Redox Biosensors. International Journal of Molecular Sciences 21:21, pages 8164.
Crossref
Crossref
Grace Santos Tavares Avelar, Leilane Oliveira Gonçalves, Frederico Gonçalves Guimarães, Paul Anderson Souza Guimarães, Luiz Gustavo do Nascimento Rocha, Maria Gabriela Reis Carvalho, Daniela de Melo Resende & Jeronimo Conceição Ruiz. (2020) Diversity and genome mapping assessment of disordered and functional domains in trypanosomatids. Journal of Proteomics 227, pages 103919.
Crossref
Crossref
Supriya Khanra, Subir Kumar Juin, Junaid Jibran Jawed, Sweta Ghosh, Shreyasi Dutta, Shaik Abdul Nabi, Jyotirmayee Dash, Dipak Dasgupta, Subrata Majumdar & Rahul Banerjee. (2020) In vivo experiments demonstrate the potent antileishmanial efficacy of repurposed suramin in visceral leishmaniasis. PLOS Neglected Tropical Diseases 14:8, pages e0008575.
Crossref
Crossref
Kedar Prayag, Dhanashree H. Surve, Atish T. Paul, Sanjay Kumar & Anil B. Jindal. (2020) Nanotechnological interventions for treatment of trypanosomiasis in humans and animals. Drug Delivery and Translational Research 10:4, pages 945-961.
Crossref
Crossref
Shailendra Yadav, Jitendra Kuldeep, Mohammad I. Siddiqi & Neena Goyal. (2020) TCP1γ Subunit Is Indispensable for Growth and Infectivity of Leishmania donovani. Antimicrobial Agents and Chemotherapy 64:8.
Crossref
Crossref
Claudio Frezza, Alessandro Venditti, Armandodoriano Bianco, Mauro Serafini, Massimo Pitorri, Fabio Sciubba, Maria Enrica Di Cocco, Eleonora Spinozzi, Loredana Cappellacci, Anders Hofer, Filippo Maggi & Riccardo Petrelli. (2020) Phytochemical Analysis and Trypanocidal Activity of Marrubium incanum Desr.. Molecules 25:14, pages 3140.
Crossref
Crossref
Devin Keck, Callie Stuart, Josie Duncan, Emily Gullette & Rodrigo Martinez-Duarte. (2020) Highly Localized Enrichment of Trypanosoma brucei Parasites Using Dielectrophoresis. Micromachines 11:6, pages 625.
Crossref
Crossref
Carla Di Chio, Santo Previti, Giorgio Amendola, Sandro Cosconati, Tanja Schirmeister, Maria Zappalà & Roberta Ettari. (2020)
Development of Novel Benzodiazepine‐Based Peptidomimetics as Inhibitors of Rhodesain from
Trypanosoma brucei rhodesiense
. ChemMedChem 15:11, pages 995-1001.
Crossref
Crossref
Isaac H. Solomon. (2020) Molecular and Histologic Diagnosis of Central Nervous System Infections. Surgical Pathology Clinics 13:2, pages 277-289.
Crossref
Crossref
Roberta Ettari, Santo Previti, Carla Di Chio, Santina Maiorana, Alessandro Allegra, Tanja Schirmeister & Maria Zappalà. (2020)
Drug Synergism: Studies of Combination of RK-52 and Curcumin against Rhodesain of
Trypanosoma brucei rhodesiense
. ACS Medicinal Chemistry Letters 11:5, pages 806-810.
Crossref
Crossref
Claudio A. Pereira, Melisa Sayé, Chantal Reigada, Ariel M. Silber, Guillermo R. Labadie, Mariana R. Miranda & Edward Valera-Vera. (2020) Computational approaches for drug discovery against trypanosomatid-caused diseases. Parasitology 147:6, pages 611-633.
Crossref
Crossref
Vasiliki Pardali, Erofili Giannakopoulou, Dimitrios-Ilias Balourdas, Vassilios Myrianthopoulos, Martin C. Taylor, Marina Šekutor, Kata Mlinarić-Majerski, John M. Kelly & Grigoris Zoidis. (2020) Lipophilic Guanylhydrazone Analogues as Promising Trypanocidal Agents: An Extended SAR Study. Current Pharmaceutical Design 26:8, pages 838-866.
Crossref
Crossref
Maria Letizia Ciavatta, Florence Lefranc, Leandro M. Vieira, Robert Kiss, Marianna Carbone, Willem A. L. van Otterlo, Nicole B. Lopanik & Andrea Waeschenbach. (2020) The Phylum Bryozoa: From Biology to Biomedical Potential. Marine Drugs 18:4, pages 200.
Crossref
Crossref
Ayanda I. Zulu, Ogunyemi O. Oderinlo, Cuan Kruger, Michelle Isaacs, Heinrich C. Hoppe, Vincent J. Smith, Clinton G. L. Veale & Setshaba D. Khanye. (2020) Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives. Molecules 25:7, pages 1668.
Crossref
Crossref
James P. Hagen, Grant Darner, Samuel Anderson, Katie Higgins, Derek A. Leas, Ananya Mitra, Victoria Mashinson, Tasloach Wol, Carlos Vera-Esquivel, Bret Belter, Monica Cal, Marcel Kaiser, Alexander Wallick, Rosalie C. Warner & Paul H. Davis. (2020) Activity of diphenyl ether benzyl amines against Human African Trypanosomiasis. Bioorganic Chemistry 97, pages 103590.
Crossref
Crossref
Jasmine Perdeh, Brandon Berioso, Quintin Love, Nicole LoGiudice, Thao Linh Le, John P. Harrelson & Sigrid C. Roberts. (2019) Critical functions of the polyamine putrescine for proliferation and viability of Leishmania donovani parasites. Amino Acids 52:2, pages 261-274.
Crossref
Crossref
Philippe Neau, Heinz Hänel, Valérie Lameyre, Nathalie Strub-Wourgaft & Luc Kuykens. (2020) Innovative Partnerships for the Elimination of Human African Trypanosomiasis and the Development of Fexinidazole. Tropical Medicine and Infectious Disease 5:1, pages 17.
Crossref
Crossref
Sarah K. Andreassend, Stephen J. Bentley, Gregory L. Blatch, Aileen Boshoff & Robert A. Keyzers. (2020) Screening for Small Molecule Modulators of Trypanosoma brucei Hsp70 Chaperone Activity Based upon Alcyonarian Coral-Derived Natural Products. Marine Drugs 18:2, pages 81.
Crossref
Crossref
Dusit Laohasinnarong. 2020. Molecular Advancements in Tropical Diseases Drug Discovery. Molecular Advancements in Tropical Diseases Drug Discovery
117
132
.
Roberta Ettari, Santo Previti, Santina Maiorana, Giorgio Amendola, Annika Wagner, Sandro Cosconati, Tanja Schirmeister, Ute A. Hellmich & Maria Zappalà. (2019) Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis. Journal of Medicinal Chemistry 62:23, pages 10617-10629.
Crossref
Crossref
Fabian Hulpia, Dorien Mabille, Gustavo D. Campagnaro, Gabriela Schumann, Louis Maes, Isabel Roditi, Anders Hofer, Harry P. de Koning, Guy Caljon & Serge Van Calenbergh. (2019) Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness. Nature Communications 10:1.
Crossref
Crossref
Leila Makhani, Aisha Khatib, Antoine Corbeil, Ruwandi Kariyawasam, Hira Raheel, Shareese Clarke, Priyanka Challa, Emma Hagopian, Sumontra Chakrabarti, Kevin L. Schwartz & Andrea K. Boggild. (2019) 2018 in review: five hot topics in tropical medicine. Tropical Diseases, Travel Medicine and Vaccines 5:1.
Crossref
Crossref
Annie N. Cowell & Elizabeth A. Winzeler. (2019) Advances in omics-based methods to identify novel targets for malaria and other parasitic protozoan infections. Genome Medicine 11:1.
Crossref
Crossref
Jieyu Tang, Yingchen Ju, Qiong Gu, Jun Xu & Huihao Zhou. (2019) Structural Insights into Substrate Recognition and Activity Regulation of the Key Decarboxylase SbnH in Staphyloferrin B Biosynthesis. Journal of Molecular Biology 431:24, pages 4868-4881.
Crossref
Crossref
Flávia Nader Motta, Clênia dos Santos Azevedo, Beatriz Pereira Neves, Carla Nunes de Araújo, Philippe Grellier, Jaime Martins de Santana & Izabela Marques Dourado Bastos. (2019) Oligopeptidase B, a missing enzyme in mammals and a potential drug target for trypanosomatid diseases. Biochimie 167, pages 207-216.
Crossref
Crossref
Julien Bonnet, Philippe Vignoles, Natalia Tiberti, Vatunga Gedeão, Alexandre Hainard, Natacha Turck, Theophile Josenando, Joseph M Ndung’u, Jean-Charles Sanchez, Bertrand Courtioux & Sylvie Bisser. (2019)
Neopterin and CXCL-13 in Diagnosis and Follow-Up of
Trypanosoma brucei gambiense
Sleeping Sickness: Lessons from the Field in Angola
. BioMed Research International 2019, pages 1-9.
Crossref
Crossref
Capela, Moreira & Lopes. (2019) An Overview of Drug Resistance in Protozoal Diseases. International Journal of Molecular Sciences 20:22, pages 5748.
Crossref
Crossref
Emma D. Deeks & Katherine A. Lyseng-Williamson. (2019) Fexinidazole in human African trypanosomiasis: a profile of its use. Drugs & Therapy Perspectives 35:11, pages 529-535.
Crossref
Crossref
Andrew Spaulding, Mitchell F. Gallerstein & Lori Ferrins. 2019. Neglected Tropical Diseases. Neglected Tropical Diseases
115
137
.
Erik de Heuvel, Abhimanyu K. Singh, Ewald Edink, Tiffany van der Meer, Melanie van der Woude, Payman Sadek, Mikkel P. Krell-Jørgensen, Toine van den Bergh, Johan Veerman, Guy Caljon, Titilola D. Kalejaiye, Maikel Wijtmans, Louis Maes, Harry P. de Koning, Geert Jan Sterk, Marco Siderius, Iwan J.P. de Esch, David G. Brown & Rob Leurs. (2019) Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors. Bioorganic & Medicinal Chemistry 27:18, pages 3998-4012.
Crossref
Crossref
Erik de Heuvel, Abhimanyu K. Singh, Pierre Boronat, Albert J. Kooistra, Tiffany van der Meer, Payman Sadek, Antoni R. Blaazer, Nathan C. Shaner, Daphne S. Bindels, Guy Caljon, Louis Maes, Geert Jan Sterk, Marco Siderius, Michael Oberholzer, Iwan J.P. de Esch, David G. Brown & Rob Leurs. (2019) Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2). Bioorganic & Medicinal Chemistry 27:18, pages 4013-4029.
Crossref
Crossref
Bahareh Feyzi Barnaji, Hamid Salehzadeh, Behzad Darbasizadeh, Rassoul Dinarvand, Abdollah Salimi & Ali Mohammadi. (2019) Electrochemical Derivatization of Acetaminophen for Indirect Determination of Eflornithine Using β‐CD Modified Glassy Carbon Electrode. Electroanalysis 31:9, pages 1719-1727.
Crossref
Crossref
Daniel Jaremko, Martin Ciganda, Linda Christen & Noreen Williams. (2019) Trypanosoma brucei L11 Is Essential to Ribosome Biogenesis and Interacts with the Kinetoplastid-Specific Proteins P34 and P37. mSphere 4:4.
Crossref
Crossref
Daniel Jaremko, Martin Ciganda & Noreen Williams. (2019) Trypanosoma brucei Homologue of Regulator of Ribosome Synthesis 1 (Rrs1) Has Direct Interactions with Essential Trypanosome-Specific Proteins. mSphere 4:4.
Crossref
Crossref
Rosa M. Reguera, Yolanda Pérez-Pertejo, Camino Gutiérrez-Corbo, Bárbara Domínguez-Asenjo, César Ordóñez, Carlos García-Estrada, María Martínez-Valladares & Rafael Balaña-Fouce. (2019) Current and promising novel drug candidates against visceral leishmaniasis. Pure and Applied Chemistry 91:8, pages 1385-1404.
Crossref
Crossref
Dennis J. Grab, Olga V. Nikolskaia, Bertrand Courtioux, Oriel M. M. Thekisoe, Stefan Magez, Maxim Bogorad, J. Stephen Dumler & Sylvie Bisser. (2019) Using detergent-enhanced LAMP for African trypanosome detection in human cerebrospinal fluid and implications for disease staging. PLOS Neglected Tropical Diseases 13:8, pages e0007631.
Crossref
Crossref
Paulo R. Cunha, Thais B. Flora & George Kroumpouzos. (2019) Travelers’ tropical skin diseases: Challenges and interventions. Dermatologic Therapy 32:4, pages e12665.
Crossref
Crossref
Samantha A. Nixon, Natalie J. Saez, Volker Herzig, Glenn F. King & Andrew C. Kotze. (2019) The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitro. Veterinary Parasitology 270, pages 40-46.
Crossref
Crossref
Ambika Dattani & Shane R. Wilkinson. (2019) Deciphering the interstrand crosslink DNA repair network expressed by Trypanosoma brucei. DNA Repair 78, pages 154-166.
Crossref
Crossref
Richard M. Beteck, Lesetja J. Legoabe, Michelle Isaacs, Setshaba D. Khanye, Dustin Laming & Heinrich C. Hoppe. (2019) Anti-Trypanosomal and Antimalarial Properties of Tetralone Derivatives and Structurally Related Benzocycloalkanones. Medicina 55:5, pages 206.
Crossref
Crossref
Paula MacGregor, Andrea L. Gonzalez-Munoz, Fatoumatta Jobe, Martin C. Taylor, Steven Rust, Alan M. Sandercock, Olivia J. S. Macleod, Katrien Van Bocxlaer, Amanda F. Francisco, Francois D’Hooge, Arnaud Tiberghien, Conor S. Barry, Philip Howard, Matthew K. Higgins, Tristan J. Vaughan, Ralph Minter & Mark Carrington. (2019) A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis. PLOS Neglected Tropical Diseases 13:5, pages e0007373.
Crossref
Crossref
Cláudia Moreno, Adriana Temporão, Taffarel Torres & Marcelo Sousa Silva. (2019) Trypanosoma brucei Interaction with Host: Mechanism of VSG Release as Target for Drug Discovery for African Trypanosomiasis. International Journal of Molecular Sciences 20:6, pages 1484.
Crossref
Crossref
Emmanuel Bottieau & Jan Clerinx. (2019) Human African Trypanosomiasis. Infectious Disease Clinics of North America 33:1, pages 61-77.
Crossref
Crossref
Charles Nnadi, Godwin Ebiloma, Jennifer Black, Ngozi Nwodo, Leandro Lemgruber, Thomas Schmidt & Harry de Koning. (2019) Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs. Molecules 24:2, pages 268.
Crossref
Crossref
Chonny Herrera Acevedo, Luciana Scotti, Mateus F. Alves, Margareth de F.F.M. Diniz & Marcus Tullius Scotti. (2019) Hybrid Compounds in the Search for Alternative Chemotherapeutic Agents against Neglected Tropical Diseases. Letters in Organic Chemistry 16:2, pages 81-92.
Crossref
Crossref
Annette Kaiser. (2019) Druggable Targets in Cyclic Nucleotide Signaling Pathways in Apicomplexan Parasites and Kinetoplastids against Disabling Protozoan Diseases in Humans. International Journal of Molecular Sciences 20:1, pages 138.
Crossref
Crossref
Magambo Phillip Kimuda, Dustin Laming, Heinrich C. Hoppe & Özlem Tastan Bishop. (2019) Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays. Molecules 24:1, pages 142.
Crossref
Crossref
Supriya Khanra, Y. Pavan Kumar, Jyotirmayee Dash & Rahul Banerjee. (2018) In vitro screening of known drugs identified by scaffold hopping techniques shows promising leishmanicidal activity for suramin and netilmicin. BMC Research Notes 11:1.
Crossref
Crossref
Sanjay Varikuti, Bijay Kumar Jha, Greta Volpedo, Nathan M. Ryan, Gregory Halsey, Omar M. Hamza, Bradford S. McGwire & Abhay R. Satoskar. (2018) Host-Directed Drug Therapies for Neglected Tropical Diseases Caused by Protozoan Parasites. Frontiers in Microbiology 9.
Crossref
Crossref
Emanuel Procházka, Veronika Michalková, Ivana Daubnerová, Ladislav Roller, Peter Klepsatel, Dušan Žitňan, George Tsiamis & Peter Takáč. (2018) Gene expression in reproductive organs of tsetse females – initial data in an approach to reduce fecundity. BMC Microbiology 18:S1.
Crossref
Crossref
Catriona H. Baker & Susan C. Welburn. (2018) The Long Wait for a New Drug for Human African Trypanosomiasis. Trends in Parasitology 34:10, pages 818-827.
Crossref
Crossref
Ignacio Fernandez-Pastor, Marta Martínez-García, Marta Medina-O’Donnell, Francisco Rivas, Antonio Martinez, José María Pérez-Victoria & Andres Parra. (2018) Semisynthesis of ω-Hydroxyalkylcarbonate Derivatives of Hydroxytyrosol as Antitrypanosome Agents. Journal of Natural Products 81:9, pages 2075-2082.
Crossref
Crossref
Maureen Gumbo, Richard Beteck, Tawanda Mandizvo, Ronnett Seldon, Digby Warner, Heinrich Hoppe, Michelle Isaacs, Dustin Laming, Christina Tam, Luisa Cheng, Nicole Liu, Kirkwood Land & Setshaba Khanye. (2018) Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity. Molecules 23:8, pages 2038.
Crossref
Crossref
Alessandra Almeida Filardy, Kamila Guimarães-Pinto, Marise Pinheiro Nunes, Ketiuce Zukeram, Lara Fliess, Ludimila Pereira, Danielle Oliveira Nascimento, Luciana Conde & Alexandre Morrot. (2018) Human Kinetoplastid Protozoan Infections: Where Are We Going Next?. Frontiers in Immunology 9.
Crossref
Crossref
Sirajudheen Anwar. (2018) Pharmacological Investigation of Solanum incanum against P. falciparum, L. infantum, T. cruzi and T. brucei : A Role of Antioxidant Effect and Clinical Overview. Biomedical and Pharmacology Journal 11:2, pages 653-660.
Crossref
Crossref
Fabricio Castro Machado, Caio Haddad Franco, Jose Vitorino dos Santos Neto, Karina Luiza Dias-Teixeira, Carolina Borsoi Moraes, Ulisses Gazos Lopes, Bertal Huseyin Aktas & Sergio Schenkman. (2018) Identification of di-substituted ureas that prevent growth of trypanosomes through inhibition of translation initiation. Scientific Reports 8:1.
Crossref
Crossref
Ning Zhang, Martin Zoltner, Ka-Fai Leung, Paul Scullion, Sebastian Hutchinson, Ricardo C. del Pino, Isabel M. Vincent, Yong-Kang Zhang, Yvonne R. Freund, Michael R. K. Alley, Robert T. Jacobs, Kevin D. Read, Michael P. Barrett, David Horn & Mark C. Field. (2018) Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles. PLOS Pathogens 14:2, pages e1006850.
Crossref
Crossref
Nicole LoGiudice, Linh Le, Irene Abuan, Yvette Leizorek & Sigrid Roberts. (2018) Alpha-Difluoromethylornithine, an Irreversible Inhibitor of Polyamine Biosynthesis, as a Therapeutic Strategy against Hyperproliferative and Infectious Diseases. Medical Sciences 6:1, pages 12.
Crossref
Crossref
JOHN G. M. MINA & P. W. DENNY. (2017) Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis. Parasitology 145:2, pages 134-147.
Crossref
Crossref
Muthusamy Venkatraj, Irene G. Salado, Jan Heeres, Jurgen Joossens, Paul J. Lewi, Guy Caljon, Louis Maes, Pieter Van der Veken & Koen Augustyns. (2018) Novel triazine dimers with potent antitrypanosomal activity. European Journal of Medicinal Chemistry 143, pages 306-319.
Crossref
Crossref
David J. Roberts. 2018. Hematology. Hematology
2278
2303.e6
.
María E. Lombardo & Alcira Batlle. 2018. Sesquiterpene Lactones. Sesquiterpene Lactones
223
240
.
Scott Worswick & Sean Dreyer. 2018. Biologic and Systemic Agents in Dermatology. Biologic and Systemic Agents in Dermatology
471
494
.
Jaime Franco, Florencia Sardi, László Szilágyi, Katalin E. Kövér, Krisztina Fehér & Marcelo A. Comini. (2017) Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes. International Journal for Parasitology: Drugs and Drug Resistance 7:3, pages 303-313.
Crossref
Crossref
Conrad L. Epting, Brian T. Emmer, Nga Y. Du, Joann M. Taylor, Ming Y. Makanji, Cheryl L. Olson & David M. Engman. (2017) Cell Cycle Inhibition To Treat Sleeping Sickness. mBio 8:5.
Crossref
Crossref
Xinying Wang, Daniel Ken Inaoka, Tomoo Shiba, Emmanuel Oluwadare Balogun, Stefan Allmann, Yoh-ichi Watanabe, Michael Boshart, Kiyoshi Kita & Shigeharu Harada. (2017) Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei. Protein Expression and Purification 138, pages 56-62.
Crossref
Crossref
Christine M. Kamidi, Norah P. Saarman, Kirstin Dion, Paul O. Mireji, Collins Ouma, Grace Murilla, Serap Aksoy, Achim Schnaufer & Adalgisa Caccone. (2017) Multiple evolutionary origins of Trypanosoma evansi in Kenya. PLOS Neglected Tropical Diseases 11:9, pages e0005895.
Crossref
Crossref
Catherine Sullenberger, Daniel Piqué, Yuko Ogata & Kojo Mensa-Wilmot. (2017) AEE788 Inhibits Basal Body Assembly and Blocks DNA Replication in the African Trypanosome. Molecular Pharmacology 91:5, pages 482-498.
Crossref
Crossref
Alfred K. Njamnshi, George Gettinby & Peter G. E. Kennedy. (2017) The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question. Transactions of The Royal Society of Tropical Medicine and Hygiene 111:5, pages 199-203.
Crossref
Crossref
Darío E. Balcazar, María Cristina Vanrell, Patricia S. Romano, Claudio A. Pereira, Fernando A. Goldbaum, Hernán R. Bonomi & Carolina Carrillo. (2017) The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists. PLOS Neglected Tropical Diseases 11:4, pages e0005513.
Crossref
Crossref
Louise E. Kerry, Elaine E. Pegg, Donald P. Cameron, James Budzak, Gretchen Poortinga, Katherine M. Hannan, Ross D. Hannan & Gloria Rudenko. (2017) Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis. PLOS Neglected Tropical Diseases 11:3, pages e0005432.
Crossref
Crossref
Cecilia Shi Ni Loo, Nelson Siu Kei Lam, Deying Yu, Xin-zhuan Su & Fangli Lu. (2017) Artemisinin and its derivatives in treating protozoan infections beyond malaria. Pharmacological Research 117, pages 192-217.
Crossref
Crossref
Chonny Herrera Acevedo, Luciana Scotti, Mateus Feitosa Alves, Margareth Formiga Melo Diniz & Marcus Scotti. (2017) Computer-Aided Drug Design Using Sesquiterpene Lactones as Sources of New Structures with Potential Activity against Infectious Neglected Diseases. Molecules 22:1, pages 79.
Crossref
Crossref
Wenbo Zhou, Yan Wang, Jiashu Xie & Robert J. Geraghty. (2017) A fluorescence-based high-throughput assay to identify inhibitors of tyrosylprotein sulfotransferase activity. Biochemical and Biophysical Research Communications 482:4, pages 1207-1212.
Crossref
Crossref
María-Jesús Pinazo, Edelweiss Aldasoro, Antonia Calvo-Cano, Albert Picado, Jose Muñoz & Joaquim Gascon. 2017. Infectious Diseases. Infectious Diseases
1751
1762.e1
.
Swati Pund & Amita Joshi. 2017. Nano- and Microscale Drug Delivery Systems. Nano- and Microscale Drug Delivery Systems
439
480
.
J.M. Withers, G. Padroni, S.M. Pauff, A.W. Clark, S.P. Mackay & G.A. Burley. 2017. Comprehensive Supramolecular Chemistry II. Comprehensive Supramolecular Chemistry II
149
178
.
Jose A. Garcia-Salcedo, Juan D. Unciti-Broceta, Javier Valverde-Pozo & Miguel Soriano. (2016) New Approaches to Overcome Transport Related Drug Resistance in Trypanosomatid Parasites. Frontiers in Pharmacology 7.
Crossref
Crossref
Simon A. Young, Matthew D. Roberts & Terry K. Smith. 2016. Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery. Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery
343
369
.
Kamal Ahmed, Holly Shaw, Alexey Koval & Vladimir Katanaev. (2016) A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers. Cancers 8:7, pages 66.
Crossref
Crossref
Benoît Stijlemans, Guy Caljon, Jan Van Den Abbeele, Jo A. Van Ginderachter, Stefan Magez & Carl De Trez. (2016) Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity. Frontiers in Immunology 7.
Crossref
Crossref
David F. Bruhn, Susan Wyllie, Adaris Rodríguez-Cortés, Angela K. Carrillo, Rakesh, R. Kiplin Guy, Alan H. Fairlamb & Richard E. Lee. (2016) Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes. Journal of Antimicrobial Chemotherapy 71:4, pages 956-963.
Crossref
Crossref
Paul Smith, C. Kiong Ho, Yuko Takagi, Hakim Djaballah & Stewart Shuman. (2016) Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase. mBio 7:1.
Crossref
Crossref
Lynne Shore Garcia. 2016. Diagnostic Medical Parasitology. Diagnostic Medical Parasitology
1134
1173
.
Stephan Zimmermann, Laurence Hall, Sean Riley, Jesper Sørensen, Rommie E. Amaro & Achim Schnaufer. (2016)
A novel high-throughput activity assay for the
Trypanosoma brucei
editosome enzyme REL1 and other RNA ligases
. Nucleic Acids Research 44:3, pages e24-e24.
Crossref
Crossref
Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs
737
748
.
Luis Carvalho, Marta Martínez-García, Ignacio Pérez-Victoria, José Ignacio Manzano, Vanessa Yardley, Francisco Gamarro & José M. Pérez-Victoria. (2015) The Oral Antimalarial Drug Tafenoquine Shows Activity against Trypanosoma brucei. Antimicrobial Agents and Chemotherapy 59:10, pages 6151-6160.
Crossref
Crossref
Netsanet Worku, August Stich, Arwid Daugschies, Iris Wenzel, Randy Kurz, Rene Thieme, Susanne Kurz & Gerd Birkenmeier. (2015) Ethyl Pyruvate Emerges as a Safe and Fast Acting Agent against Trypanosoma brucei by Targeting Pyruvate Kinase Activity. PLOS ONE 10:9, pages e0137353.
Crossref
Crossref
Gisele A. B. Canuto, Pedro L. R. da Cruz, Andrea T. Faccio, Aline Klassen & Marina F. M. Tavares. (2015) Neglected diseases prioritized in Brazil under the perspective of metabolomics: A review. ELECTROPHORESIS 36:18, pages 2336-2347.
Crossref
Crossref
S. Pomel, F. Dubar, D. Forge, P.M. Loiseau & C. Biot. (2015) New heterocyclic compounds: Synthesis and antitrypanosomal properties. Bioorganic & Medicinal Chemistry 23:16, pages 5168-5174.
Crossref
Crossref
Emanuele Amata, Nicholas D. Bland, Robert K. Campbell & Michael P. Pollastri. (2015) Evaluation of pyrrolidine and pyrazolone derivatives as inhibitors of trypanosomal phosphodiesterase B1 (TbrPDEB1). Tetrahedron Letters 56:21, pages 2832-2835.
Crossref
Crossref
Ramon Garcia-Domenech, Riccardo Zanni, Maria Galvez-Llompart & Jorge Galvez. (2015) Predicting antiprotozoal activity of benzyl phenyl ether diamine derivatives through QSAR multi-target and molecular topology. Molecular Diversity 19:2, pages 357-366.
Crossref
Crossref
Francesca F Norman, Begoña Monge-Maillo, Ángela Martínez-Pérez, Jose A Perez-Molina & Rogelio López-Vélez. (2015) Parasitic infections in travelers and immigrants: part I protozoa. Future Microbiology 10:1, pages 69-86.
Crossref
Crossref
Joana Faria, Carolina B. Moraes, Rita Song, Bruno S. Pascoalino, Nakyung Lee, Jair L. Siqueira-Neto, Deu John M. Cruz, Tanya Parkinson, Jean-Robert Ioset, Anabela Cordeiro-da-Silva & Lucio H. Freitas-Junior. (2015) Drug Discovery for Human African Trypanosomiasis: Identification of Novel Scaffolds by the Newly Developed HTS SYBR Green Assay for Trypanosoma brucei. SLAS Discovery 20:1, pages 70-81.
Crossref
Crossref
Sanaa E. Jehi, Xiaohua Li, Ranjodh Sandhu, Fei Ye, Imaan Benmerzouga, Mingjie Zhang, Yanxiang Zhao & Bibo Li. (2014) Suppression of subtelomeric VSG switching by Trypanosoma brucei TRF requires its TTAGGG repeat-binding activity. Nucleic Acids Research 42:20, pages 12899-12911.
Crossref
Crossref
Mariana P. Torrente, Laura M. Castellano & James Shorter. (2014) Suramin Inhibits Hsp104 ATPase and Disaggregase Activity. PLoS ONE 9:10, pages e110115.
Crossref
Crossref
Tim K. Mackey, Bryan A. Liang, Raphael Cuomo, Ryan Hafen, Kimberly C. Brouwer & Daniel E. Lee. (2014) Emerging and Reemerging Neglected Tropical Diseases: a Review of Key Characteristics, Risk Factors, and the Policy and Innovation Environment. Clinical Microbiology Reviews 27:4, pages 949-979.
Crossref
Crossref
Lauren Sullivan, Jennifer Fleming, Lalitha Sastry, Angela Mehlert, Steven J. Wall & Michael A. J. Ferguson. (2014) Identification of sVSG117 as an Immunodiagnostic Antigen and Evaluation of a Dual-Antigen Lateral Flow Test for the Diagnosis of Human African Trypanosomiasis. PLoS Neglected Tropical Diseases 8:7, pages e2976.
Crossref
Crossref
Puhua Wu, Jiong Zhang, Qingqing Meng, Bakela Nare, Robert T. Jacobs & Huchen Zhou. (2014) Novel pyrrolobenzoxaboroles: Design, synthesis, and biological evaluation against Trypanosoma brucei. European Journal of Medicinal Chemistry 81, pages 59-75.
Crossref
Crossref
Angela Maria Arenas Velásquez, Acácio Ivo Francisco, Andréa Akiko Nakaima Kohatsu, Flavia Alves de Jesus Silva, Danilo Fernando Rodrigues, Rafaela Gomes da Silva Teixeira, Bruna Galdorfini Chiari, Maria Gabriela José de Almeida, Vera Lucia Borges Isaac, Maria D. Vargas & Regina Maria Barretto Cicarelli. (2014) Synthesis and tripanocidal activity of ferrocenyl and benzyl diamines against Trypanosoma brucei and Trypanosoma cruzi. Bioorganic & Medicinal Chemistry Letters 24:7, pages 1707-1710.
Crossref
Crossref