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Anticancer Chemotherapy

Pharmacokinetics of Bolus 5-Fluorouracil: Relationship Between Dose, Plasma Concentrations, Area-Under-the-Curve and Toxicity

Pages 315-320 | Published online: 18 Jul 2013

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Eduard Schmulenson, Nigina Zimmermann, Gerd Mikus, Markus Joerger & Ulrich Jaehde. (2021) Current status and future outlooks on therapeutic drug monitoring of fluorouracil. Expert Opinion on Drug Metabolism & Toxicology 17:12, pages 1407-1422.
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Lonneke Timmers, Eleonora L Swart, Christel CLM Boons, Dirk Mangnus, Peter M van de Ven, Godefridus J Peters, Epie Boven & Jacqueline G Hugtenburg. (2012) The use of capecitabine in daily practice: a study on adherence and patients’ experiences. Patient Preference and Adherence 6, pages 741-748.
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A.B. P. van Kuilenburg, J.G. Maring, A. Schalhorn, C. Terborg, H. Schmalenberg, D. Behnke, W. Schwabe, K. Jabschinsky & P. Hausler. (2008) Pharmacokinetics of 5-Fluorouracil in Patients Heterozygous for the IVS14+1G > A Mutation in the Dihydropyrimidine Dehydrogenase Gene. Nucleosides, Nucleotides & Nucleic Acids 27:6-7, pages 692-698.
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Articles from other publishers (7)

Markus Joerger, Christoph Ritter & Susen Burock. 2020. Kompendium Internistische Onkologie. Kompendium Internistische Onkologie 1 8 .
Seema Kohli & Lavakesh Kumar Omray. 2022. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology. Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology 165 179 .
Bushra Salman & Murtadha Al-Khabori. (2020) Applications and challenges in therapeutic drug monitoring of cancer treatment: A review. Journal of Oncology Pharmacy Practice 27:3, pages 693-701.
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André BP van KuilenburgJan Gerard Maring. (2013) Evaluation of 5-fluorouracil pharmacokinetic models and therapeutic drug monitoring in cancer patients. Pharmacogenomics 14:7, pages 799-811.
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André B. P. van Kuilenburg, Peter Häusler, Andreas Schalhorn, Michael W. T. Tanck, Johannes H. Proost, Christoph Terborg, Detlev Behnke, Wolfgang Schwabe, Kati Jabschinsky & Jan Gerard Maring. (2012) Evaluation of 5-Fluorouracil Pharmacokinetics in Cancer Patients with a C.1905+1G>A Mutation in DPYD by Means of a Bayesian Limited Sampling Strategy. Clinical Pharmacokinetics 51:3, pages 163-174.
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M Gusella, A C Frigo, C Bolzonella, R Marinelli, C Barile, A Bononi, G Crepaldi, D Menon, L Stievano, S Toso, F Pasini, E Ferrazzi & R Padrini. (2009) Predictors of survival and toxicity in patients on adjuvant therapy with 5-fluorouracil for colorectal cancer. British Journal of Cancer 100:10, pages 1549-1557.
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M. Gusella, G. Crepaldi, C. Barile, A. Bononi, D. Menon, S. Toso, D. Scapoli, L. Stievano, E. Ferrazzi, F. Grigoletto, M. Ferrari & R. Padrini. (2006) Pharmacokinetic and demographic markers of 5-fluorouracil toxicity in 181 patients on adjuvant therapy for colorectal cancer. Annals of Oncology 17:11, pages 1656-1660.
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