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Current Medical Research and Opinion Volume 25, 2009 - Issue 2
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Original Article

Twelve years’ experience with methotrexate for GINA treatment step 5 asthma patients

Christian Domingo Pulmonary Service, Parc Taulí Corporation, Sabadell, Spain; Department of Medicine, Autonomous University of Bellaterra, Barcelona, SpainCorrespondence[email protected]
,
Amalia Moreno Pulmonary Service, Parc Taulí Corporation, Sabadell, Spain; Department of Medicine, Autonomous University of Bellaterra, Barcelona, Spain
,
MªJosé Amengual Laboratory Service, Section of Immunology, UDIAT, Parc Taulí Corporation, Sabadell, Spain
,
Ricard Comet Department of Medicine, Autonomous University of Bellaterra, Barcelona, Spain; Service of Internal Medicine, Parc Taulí Corporation, Sabadell, Spain
&
Manel Luján Pulmonary Service, Parc Taulí Corporation, Sabadell, Spain; Department of Medicine, Autonomous University of Bellaterra, Barcelona, Spain
Pages 367-374 | Accepted 17 Nov 2008, Published online: 19 Dec 2008

Citations (14)

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Read on this site (5)

Daniel Colodenco, Oscar Palomares, Carlos Celis, Alan Kaplan & Christian Domingo. (2018) Moving toward consensus on diagnosis and management of severe asthma in adults. Current Medical Research and Opinion 34:3, pages 387-399.
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Alexandros Kalkanis & Marc A. Judson. (2013) Distinguishing Asthma from Sarcoidosis: An Approach to a Problem that is not Always Solvable. Journal of Asthma 50:1, pages 1-6.
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Christian Domingo, Amalia Moreno, M José Amengual, Concepción Montón, David Suárez & Xavier Pomares. (2011) Omalizumab in the management of oral corticosteroid-dependent IGE-mediated asthma patients. Current Medical Research and Opinion 27:1, pages 45-53.
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Jaymin B Morjaria & Riccardo Polosa. (2010) Recommendation for optimal management of severe refractory asthma. Journal of Asthma and Allergy 3, pages 43-56.
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S. Buyukozturk, A. Gelincik, I. Aslan, S. Aydin, B. Colakoglu & M. Dal. (2009) Methotrexate: Can it be a Choice for Nasal Polyposis in Aspirin Exacerbated Respiratory Disease?. Journal of Asthma 46:10, pages 1037-1041.
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Articles from other publishers (9)

Christian Domingo, Xavier Pomares, Anisi Morón & Ana Sogo. (2020) Dual Monoclonal Antibody Therapy for a Severe Asthma Patient. Frontiers in Pharmacology 11.
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Christian Domingo, Xavier Pomares, Albert Navarro, María José Amengual, Concepción Montón, Ana Sogo & Rosa M. Mirapeix. (2018) A step-down protocol for omalizumab treatment in oral corticosteroid-dependent allergic asthma patients. British Journal of Clinical Pharmacology 84:2, pages 339-348.
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Kyung Wook Heo, Seong Kook Park, Yeo Myeong Lee, Si Hong Choe, Pyung Mo Gu, Tae Ui Hong & Dae Young Hur. (2017) Methotrexate Induces Apoptosis in Organ-Cultured Nasal Polyps Via the Fas Pathway. Journal of Craniofacial Surgery 28:3, pages 806-809.
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Riccardo Polosa, Salvatore Bellinvia, Massimo Caruso, Rosalia Emma, Angela Alamo, Marek Leszek Kowalski & Christian Domingo. (2014) Weekly low-dose methotrexate for reduction of Global Initiative for Asthma Step 5 treatment in severe refractory asthma: study protocol for a randomized controlled trial. Trials 15:1.
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Christian Domingo. (2014) Omalizumab for Severe Asthma: Efficacy Beyond the Atopic Patient?. Drugs 74:5, pages 521-533.
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Hong Wook Cho, Seong Kook Park, Kyung Wook Heo & Dae Young Hur. (2013) Methotrexate Induces Apoptosis in Nasal Polyps via Caspase Cascades and Both Mitochondria-Mediated and p38 Mitogen-Activated Protein Kinases/Jun N-terminal Kinase Pathways . American Journal of Rhinology & Allergy 27:1, pages e26-e31.
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Manel Luján, Xavier Gallardo, María José Amengual, Montserrat Bosque, Rosa M. Mirapeix & Christian Domingo. (2013) Prevalence of Bronchiectasis in Asthma according to Oral Steroid Requirement: Influence of Immunoglobulin Levels. BioMed Research International 2013, pages 1-7.
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Seong Kook Park, Hyeong In Kim, Young Il Yang & Dae Young Hur. (2011) Effects of Methotrexate on Vascular Endothelial Growth Factor, Angiopoietin 1, and Angiopoietin 2 in Nasal Polyps. American Journal of Rhinology & Allergy 25:4, pages e129-e132.
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C. Domingo, A. Moreno & R. Mirapeix. (2011) Rationale for the use of immunomodulatory therapies in the Global Initiative for Asthma (GINA) step V asthma other than oral glucocorticosteroids. Internal Medicine Journal 41:7, pages 525-536.
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