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Original Article

GLP-1 receptor agonists and HBA1c target of <7% in type 2 diabetes: meta-analysis of randomized controlled trials

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Pages 1519-1528 | Accepted 18 May 2011, Published online: 13 Jun 2011

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D Cimmaruta, MI Maiorino, C Scavone, L Sportiello, F Rossi, D Giugliano, K Esposito & A Capuano. (2016) Efficacy and safety of insulin-GLP-1 receptor agonists combination in type 2 diabetes mellitus: a systematic review. Expert Opinion on Drug Safety 15:sup2, pages 77-83.
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Edoardo Mannucci & Ilaria Dicembrini. (2012) Incretin-based therapies and cardiovascular risk. Current Medical Research and Opinion 28:5, pages 715-721.
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Jessica E. Potts, Laura J. Gray, Emer M. Brady, Kamlesh Khunti, Melanie J. Davies & Danielle H. Bodicoat. (2015) The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: A Systematic Review and Mixed Treatment Comparison Meta-Analysis. PLOS ONE 10:6, pages e0126769.
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Luc Van Gaal & André Scheen. (2015) Weight Management in Type 2 Diabetes: Current and Emerging Approaches to Treatment. Diabetes Care 38:6, pages 1161-1172.
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Jia Liu, Guang Wang, Yumei Jia & Yuan Xu. (2015) GLP-1 receptor agonists: effects on the progression of non-alcoholic fatty liver disease. Diabetes/Metabolism Research and Reviews 31:4, pages 329-335.
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Y. G. Kim, S. Hahn, T. J. Oh, K. S. Park & Y. M. Cho. (2014) Differences in the HbA1c-lowering efficacy of glucagon-like peptide-1 analogues between Asians and non-Asians: a systematic review and meta-analysis. Diabetes, Obesity and Metabolism 16:10, pages 900-909.
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Zachary T Bloomgarden. (2014) Basal insulin or longacting GLP-1 receptor agonists—making the right choice. The Lancet Diabetes & Endocrinology 2:6, pages 439-441.
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Miguel Camafort-Babkowski. (2013) Impacto del tratamiento antidiabético con fármacos agonistas del receptor de péptido de tipo 1 similar al glucagón en el riesgo cardiovascular de pacientes con diabetes mellitus tipo 2. Medicina Clínica 141:4, pages 167-174.
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Robert R. Henry, Douglas Logan, Thomas Alessi & Michelle A. Baron. (2013) A Randomized, Open-Label, Multicenter, 4-Week Study to Evaluate the Tolerability and Pharmacokinetics of ITCA 650 in Patients With Type 2 Diabetes☆☆This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.. Clinical Therapeutics 35:5, pages 634-645.e1.
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Young Min ChoRhonda D. WidemanTimothy J. Kieffer. (2013) Clinical Application of Glucagon-Like Peptide 1 Receptor Agonists for the Treatment of Type 2 Diabetes Mellitus. Endocrinology and Metabolism 28:4, pages 262.
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K. Fosgerau, L. Jessen, J. Lind Tolborg, T. Østerlund, K. Schaeffer Larsen, K. Rolsted, M. Brorson, J. Jelsing & T. Skovlund Ryge Neerup. (2013) The novel GLP-1-gastrin dual agonist, ZP3022, increases β-cell mass and prevents diabetes in db/db mice. Diabetes, Obesity and Metabolism 15:1, pages 62-71.
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A. R. Meloni, M. B. DeYoung, C. Lowe & D. G. Parkes. (2012) GLP ‐1 receptor activated insulin secretion from pancreatic β‐cells: mechanism and glucose dependence . Diabetes, Obesity and Metabolism 15:1, pages 15-27.
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Jeffrey S. Freeman. (2013) Evidence from randomized clinical trials demonstrating improved glycemic control with GLP-1 receptor agonists when used with other agents vs other combination therapy strategies. Osteopathic Family Physician 5:1, pages 43-50.
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S. Paul, J. Best, K. Klein, J. Han & D. Maggs. (2012) Effects of HbA 1c and weight reduction on blood pressure in patients with type 2 diabetes mellitus treated with exenatide * . Diabetes, Obesity and Metabolism 14:9, pages 826-834.
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Vanita R. Aroda, Robert R. Henry, Jenny Han, Wenying Huang, Mary Beth DeYoung, Tamara Darsow & Byron J. Hoogwerf. (2012) Efficacy of GLP-1 Receptor Agonists and DPP-4 Inhibitors: Meta-Analysis and Systematic Review. Clinical Therapeutics 34:6, pages 1247-1258.e22.
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