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Editorial

Are statins ‘IDEAL’ for non-alcoholic fatty liver disease?

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Pages 229-231 | Accepted 09 Oct 2013, Published online: 28 Oct 2013

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S. S. Iyengar, R. Puri, S. N. Narasingan, D. R. Nair, V. Mehta, J. C. Mohan, S. K. Wangnoo, J. J. Dalal, V. Jha, S. Puri, A. Misra, M. K. Daga, M. Varma, S. Jasuja, S. Upadhyaya, R. R. Kasliwal, M. Bansal, R. Mehrotra, A. Jain, K. K. Talwar, R. Rajput, A. Pradhan, S. Seth, D. Kapoor, R. P. Melinkeri, S. Ramakrishnan, N. N. Khanna, R. Khadgawat, S. Puri, A. Shaikh, N. Kovalipati, N. Bordoloi, A. H. Zargar, R. K. Agarwal, A. Rastogi, M. Chag, D. Prabhakar, S. K. Mathur, H. Rehan, P. K. Sahoo, A. Dutta, A. Sharma, A. K. Pancholia, K. U. Natarajan, A. Mishra & K. Singh. (2017) Lipid Association of India (LAI) expert consensus statement on management of dyslipidaemia in Indians 2017: part 2. Clinical Lipidology 12:1, pages 56-109.
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Vasilios G. Athyros, Niki Katsiki & Asterios Karagiannis. (2016) Off target effects of statins shape total mortality?. Journal of Drug Assessment 5:1, pages 4-5.
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Maciej Banach, Manfredi Rizzo, Peter P Toth, Michel Farnier, Michael H Davidson, Khalid Al-Rasadi, Wilbert S Aronow, Vasilis Athyros, Dragan M Djuric, Marat V Ezhov, Robert S Greenfield, G Kees Hovingh, Karam Kostner, Corina Serban, Daniel Lighezan, Zlatko Fras, Patrick M Moriarty, Paul Muntner, Assen Goudev, Richard Ceska, Stephen J Nicholls, Marlena Broncel, Dragana Nikolic, Daniel Pella, Raman Puri, Jacek Rysz, Nathan D Wong, Laszlo Bajnok, Steven R Jones, Kausik K Ray & Dimitri P Mikhailidis. (2015) Statin intolerance – an attempt at a unified definition. Position paper from an International Lipid Expert Panel. Expert Opinion on Drug Safety 14:6, pages 935-955.
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Mariana Verdelho Machado & Helena Cortez-Pinto. (2014) Management of fatty liver disease with the metabolic syndrome. Expert Review of Gastroenterology & Hepatology 8:5, pages 487-500.
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Articles from other publishers (15)

Georgios Sfikas, Michael Psallas, Charalambos Koumaras, Konstantinos Imprialos, Evangelos Perdikakis, Michael Doumas, Olga Giouleme, Asterios Karagiannis & Vasilios G. Athyros. (2021) Prevalence, Diagnosis, and Treatment with 3 Different Statins of Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis in Military Personnel. Do Genetics Play a Role?. Current Vascular Pharmacology 19:5, pages 572-581.
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Ziwei Li, Yuanfeng Lyu, Jiajia Zhao, Dan Li, Zhixiu Lin, Kenneth Kin Wah To, Xiaoyu Yan & Zhong Zuo. (2021) Disease Status–Dependent Drug–Herb Interactions: NASH Lowered the Risk of Hepatotoxicity in Rats Coadministered With Simvastatin and Gardenia jasminoides J. Ellis. Frontiers in Pharmacology 12.
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Ke Pei, Ting Gui, Dongfang Kan, Huichao Feng, Yanqiang Jin, Ying Yang, Qian Zhang, Ziwei Du, Zhibo Gai, Jibiao Wu & Yunlun Li. (2020) An Overview of Lipid Metabolism and Nonalcoholic Fatty Liver Disease. BioMed Research International 2020, pages 1-12.
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Shogo Watanabe, Shota Kumazaki, Shusei Yamamoto, Ikumi Sato, Kazuya Kitamori, Mari Mori, Yukio Yamori & Satoshi Hirohata. (2018) Non-alcoholic steatohepatitis aggravates nitric oxide synthase inhibition-induced arteriosclerosis in SHRSP5/Dmcr rat model. International Journal of Experimental Pathology 99:6, pages 282-294.
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Xing Gao, Yang Nan, Yuanlin Zhao, Yuan Yuan, Bincheng Ren, Chao Sun, Kaiyu Cao, Ming Yu, Xuyang Feng & Jing Ye. (2017) Atorvastatin reduces lipid accumulation in the liver by activating protein kinase A-mediated phosphorylation of perilipin 5. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1862:12, pages 1512-1519.
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Shi Peng Zhao, Zhi Sheng Wu, Yu Chen, Xue Liang, Lei Bao, Pin Li, Ran Ran Sun, Yan Ling Wu, Ling Ru Li & Qi Wang. (2017) Protective effect of Hua Tan Qu Shi decoction against liver injury in rats with nonalcoholic fatty liver disease. Biomedicine & Pharmacotherapy 91, pages 181-190.
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Vasilios G. Athyros, Theodore K. Alexandrides, Helen Bilianou, Evangelos Cholongitas, Michael Doumas, Emmanuel S. Ganotakis, John Goudevenos, Moses S. Elisaf, Georgios Germanidis, Olga Giouleme, Asterios Karagiannis, Charalambos Karvounis, Niki Katsiki, Vasilios Kotsis, Jannis Kountouras, Evangelos Liberopoulos, Christos Pitsavos, Stergios Polyzos, Loukianos S. Rallidis, Dimitrios Richter, Apostolos G. Tsapas, Alexandros D. Tselepis, Konstantinos Tsioufis, Konstantinos Tziomalos, Themistoklis Tzotzas, Themistoklis G. Vasiliadis, Charalambos Vlachopoulos, Dimitri P. Mikhailidis & Christos Mantzoros. (2017) The use of statins alone, or in combination with pioglitazone and other drugs, for the treatment of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and related cardiovascular risk. An Expert Panel Statement. Metabolism 71, pages 17-32.
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Tomasz Charytoniuk, Krzysztof Drygalski, Karolina Konstantynowicz-Nowicka, Klaudia Berk & Adrian Chabowski. (2017) Alternative treatment methods attenuate the development of NAFLD: A review of resveratrol molecular mechanisms and clinical trials. Nutrition 34, pages 108-117.
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Robert Schierwagen, Lara MaybüchenKanishka HittatiyaSabine KleinFrank E. UschnerTarcio T. BragaBernardo S. FranklinGeorg NickenigChristian P. StrassburgJogchum PlatTilman SauerbruchEicke LatzDieter Lütjohann, Sebastian ZimmerJonel Trebicka. (2016) Statins improve NASH via inhibition of RhoA and Ras. American Journal of Physiology-Gastrointestinal and Liver Physiology 311:4, pages G724-G733.
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Vasilios G Athyros, Konstantinos Tziomalos, Niki Katsiki, Michael Doumas, Asterios Karagiannis & Dimitri P Mikhailidis. (2015) Cardiovascular risk across the histological spectrum and the clinical manifestations of non-alcoholic fatty liver disease: An update. World Journal of Gastroenterology 21:22, pages 6820-6834.
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Dimitrios Papandreou. (2015) Role of diet on non-alcoholic fatty liver disease: An updated narrative review. World Journal of Hepatology 7:3, pages 575.
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Vasilios G. Athyros, Niki Katsiki, Asterios Karagiannis & Dimitri P. Mikhailidis. (2015) High-intensity statin therapy and regression of coronary atherosclerosis in patients with diabetes mellitus. Journal of Diabetes and its Complications 29:1, pages 142-145.
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Cédric Langhi, Tyler J. Marquart, Ryan M. Allen & Ángel Baldán. (2014) Perilipin-5 is regulated by statins and controls triglyceride contents in the hepatocyte. Journal of Hepatology 61:2, pages 358-365.
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I. Vasiliadis, G. Kolovou, S. Mavrogeni, D.R. Nair & D.P. Mikhailidis. (2014) Sudden cardiac death and diabetes mellitus. Journal of Diabetes and its Complications 28:4, pages 573-579.
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Mariana Verdelho Machado. (2014) Non-alcoholic fatty liver disease: What the clinician needs to know. World Journal of Gastroenterology 20:36, pages 12956.
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