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Current Medical Research and Opinion Volume 15, 1999 - Issue 3
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Research Article

Efficacy and Safety of a Fixed Combination Phytomedicine in the Treatment of the Common Cold (Acute Viral Respiratory Tract Infection): Results of a Randomised, Double Blind, Placebo Controlled, Multicentre Study

H. H. Henneicke-Von Zepelin Department of Complementary Medicine, University of Exeter, EX2 4NT, UK
,
C. Hentschel Department of Complementary Medicine, University of Exeter, EX2 4NT, UK
,
J. Schnitker Institut fur angewandte Statistik, Dr Jörg Schnitker GmbH, 33629, Bielefeld, Germany
,
R. Kohnen Institute of Psychology II, University of Erlangen-Nurnberg, Germany
,
G. Köhler
,
P. Wüstenberg Department of Complementary Medicine, University of Exeter, EX2 4NT, UK
&
(on behalf of the study group)
 show all
Pages 214-227 | Accepted 21 Jun 1999, Published online: 26 Aug 2008

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Hans-Heinrich Henneicke-von Zepelin, Petra Nicken, Belal Naser, Jennifer-Christin Kuchernig, Nicole Brien, Annette Holtdirk, Jörg Schnitker & Klaus-Ulrich Nolte. (2019) Non-interventional observational study broadens positive benefit-risk assessment of an immunomodulating herbal remedy in the common cold. Current Medical Research and Opinion 35:10, pages 1711-1719.
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Ethan Basch, Catherine Ulbricht, Samuel Basch, Sean Dalton, Edzard Ernst, Ivo Foppa, Phillippe Szapary, Natasha Tiffany, Carolyn Williams Orlando & Mamta Vora. (2005) An Evidence-Based Systematic Review of Echinacea (E. angustifolia DC, E. pallida, E. purpurea) by the Natural Standard Research Collaboration. Journal Of Herbal Pharmacotherapy 5:2, pages 57-88.
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Bruce Barrett & David Kieffer. (2001) Medicinal Plants, Science, and Health Care. Journal of Herbs, Spices & Medicinal Plants 8:2-3, pages 1-36.
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Articles from other publishers (42)

Nour Mammari, Quentin Albert, Marc Devocelle, Maša Kenda, Nina Kočevar Glavač, Marija Sollner Dolenc, Laura Mercolini, Jaroslav Tóth, Nagy Milan, Szilvia Czigle & Mihayl Varbanov. (2023) Natural Products for the Prevention and Treatment of Common Cold and Viral Respiratory Infections. Pharmaceuticals 16:5, pages 662.
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Minh Phuoc Hoang, Kachorn Seresirikachorn, Wirach Chitsuthipakorn & Kornkiat Snidvongs. (2023) Herbal Medicines for Rhinosinusitis: A Systematic Review and Network Meta-analysis. Current Allergy and Asthma Reports 23:2, pages 93-109.
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Ankit Srivastava, Bimal Prasad Jit, Rutumbara Dash, Rishi Srivastava & Sameer Srivastava. (2023) Thuja occidentalis: An Unexplored Phytomedicine with Therapeutic Applications. Combinatorial Chemistry & High Throughput Screening 26:1, pages 3-13.
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Oleksandr Duda, Iryna Manzheleeva, Valentyna Boyko, Alla Golub & Yurii Sukhov. (2022) Place of Immunostimulating Drugs in the Treatment of Respiratory Infections. Family medicine. European practices:3, pages 40-47.
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Rainer W. Bussmann. 2022. Evidence-Based Validation of Herbal Medicine. Evidence-Based Validation of Herbal Medicine 149 183 .
Jin‐Young Lee, Hahyun Park, Whasun Lim & Gwonhwa Song. (2020) Therapeutic potential of α,β‐thujone through metabolic reprogramming and caspase‐dependent apoptosis in ovarian cancer cells. Journal of Cellular Physiology 236:2, pages 1545-1558.
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Sholto David & Rebecca Cunningham. (2019) Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and meta-analysis. Complementary Therapies in Medicine 44, pages 18-26.
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Bruce Barrett. 2018. Integrative Medicine. Integrative Medicine 170 179.e7 .
Jan Martel, Yun-Fei Ko, David M. Ojcius, Chia-Chen Lu, Chih-Jung Chang, Chuan-Sheng Lin, Hsin-Chih Lai & John D. Young. (2017) Immunomodulatory Properties of Plants and Mushrooms. Trends in Pharmacological Sciences 38:11, pages 967-981.
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Belal Naser, Ute Stammwitz & Klaus-Ulrich Nolte. (2016) Baptisia Poisoning: Consideration on the Botanical Variety. The Journal of Emergency Medicine 51:3, pages e65.
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John Laird. (2015) An evidence-based review of commonly used dietary supplements. Journal of the American Academy of Physician Assistants 28:7, pages 1-5.
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Sarah E. Edwards, Inês da Costa Rocha, Elizabeth M. Williamson & Michael Heinrich. 2015. Phytopharmacy. Phytopharmacy 389 390 .
Rainer W. Bussmann. 2015. Evidence-Based Validation of Herbal Medicine. Evidence-Based Validation of Herbal Medicine 87 118 .
Marlies Karsch-Völk, Bruce Barrett, David Kiefer, Rudolf Bauer, Karin Ardjomand-Woelkart & Klaus Linde. (2014) Echinacea for preventing and treating the common cold. Cochrane Database of Systematic Reviews 2014:7.
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Bruce Barrett. 2012. Integrative Medicine. Integrative Medicine 149 157.e5 .
May Loo. 2009. Integrative Medicine for Children. Integrative Medicine for Children 450 455 .
Joelle O’Neil, Susan Hughes, Andrea Lourie & John Zweifler. (2008) Effects of echinacea on the frequency of upper respiratory tract symptoms: a randomized, double-blind, placebo-controlled trial. Annals of Allergy, Asthma & Immunology 100:4, pages 384-388.
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Bruce Barrett. 2007. Integrative Medicine. Integrative Medicine 209 220 .
Joseph S. Sanfilippo & Roger P. SmithRoger P. Smith. 2007. Primary Care in Obstetrics and Gynecology. Primary Care in Obstetrics and Gynecology 379 396 .
Roland Schoop, Samuel Büechi & Andy Suter. (2006) Open, multicenter study to evaluate the tolerability and efficacy of Echinaforce Forte tablets in athletes. Advances in Therapy 23:5, pages 823-833.
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. (2010) Limited trial reports benefit for a herbal formula for common cold. Focus on Alternative and Complementary Therapies 11:2, pages 112-114.
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Klaus Linde, Bruce Barrett, Rudolf Bauer, Dieter Melchart & Karin Woelkart. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Edward Mills, Jean-Jacques Dugoua, Dan Perri & Gideon Koren. 2006. Herbal Medicines in Pregnancy and Lactation. Herbal Medicines in Pregnancy and Lactation 27 28 .
B. Naser, B. Lund, H.-H. Henneicke-von Zepelin, G. Köhler, W. Lehmacher & F. Scaglione. (2005) A randomized, double-blind, placebo-controlled, clinical dose–response trial of an extract of Baptisia, Echinacea and Thuja for the treatment of patients with common cold. Phytomedicine 12:10, pages 715-722.
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. (2014) Abstracts. Basic & Clinical Pharmacology & Toxicology 97:S1, pages 23-128.
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Bruce Barrett. (2005) Ask the experts. EXPLORE 1:3, pages 234.
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Andrew H. Draves. (2016) Echinacea and the Common Cold. Canadian Pharmacists Journal / Revue des Pharmaciens du Canada 138:2, pages 35-40.
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B. Brinkhaus, J. Hummelsberger, R. Kohnen, J. Seufert, C.-H. Hempen, H. Leonhardy, R. Nogel, S. Joos, E. Hahn & D. Schuppan. (2004) Acupuncture and Chinese herbal medicine in the treatment of patients with seasonal allergic rhinitis: a randomized-controlled clinical trial. Allergy 59:9, pages 953-960.
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Evelyn T. AmbroseSandra Samuels. (2005) Perception and Use of Herbals Among Students and Their Practitioners in a University Setting. Journal of the American Academy of Nurse Practitioners 16:4, pages 166-173.
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Keith I. BlockMark N. Mead. (2016) Immune System Effects of Echinacea, Ginseng, and Astragalus: A Review. Integrative Cancer Therapies 2:3, pages 247-267.
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. (2010) No benefit of Echinacea in the treatment of the common cold? . Focus on Alternative and Complementary Therapies 8:2, pages 191-192.
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B. Barrett. (2003) Medicinal properties of Echinacea: A critical review. Phytomedicine 10:1, pages 66-86.
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George L. Kirkpatrick. 2003. Fundamentals of Family Medicine. Fundamentals of Family Medicine 208 225 .
George L. Kirkpatrick. 2003. Family Medicine. Family Medicine 333 340 .
Clare Stevinson. (2010) Evidence for complementary therapies for upper respiratory tract infection. Focus on Alternative and Complementary Therapies 7:3, pages 237-240.
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Thomas A. Tami & Sung J. Chung. (2002) Advances in treating the common cold: an update for otolaryngologists. Current Opinion in Otolaryngology & Head and Neck Surgery 10:3, pages 179-183.
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Raja Jaber. (2002) Respiratory and allergic diseases: from upper respiratory tract infections to asthma. Primary Care: Clinics in Office Practice 29:2, pages 231-261.
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Leonard Bielory. (2002) Adverse reactions to complementary and alternative medicine: ragweed's cousin, the coneflower (echinacea), is “a problem more than a sneeze”. Annals of Allergy, Asthma & Immunology 88:1, pages 7-9.
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Patrick B Massey. (2002) Dietary supplements. Medical Clinics of North America 86:1, pages 127-147.
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W. Hauke, G. Köhler, G. Schmieder, H.-H. Henneicke-von Zepelin & J. Freudenstein. 2002. Phytopharmaka VII. Phytopharmaka VII 41 51 .
M Petri. (2016) Diet and systemic lupus erythematosus: from mouse and monkey to woman?. Lupus 10:11, pages 775-777.
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R TURNER. (2001) The treatment of rhinovirus infections: progress and potential. Antiviral Research 49:1, pages 1-14.
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