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Original Articles

Protection by the Flavonoids Myricetin, Quercetin, and Rutin Against Hydrogen Peroxide-Induced DNA Damage in Caco-2 and Hep G2 Cells

Pages 160-166 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Arakkaveettil Kabeer Farha, Ren-You Gan, Hua-Bin Li, Ding-Tao Wu, Atanas G. Atanasov, Khalid Gul, Jia-Rong Zhang, Qiong-Qiong Yang & Harold Corke. (2022) The anticancer potential of the dietary polyphenol rutin: Current status, challenges, and perspectives. Critical Reviews in Food Science and Nutrition 62:3, pages 832-859.
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Hai Peng Lu, Ya Nan Jia, Yan Yu & Li Xu. (2017) DNA protection activity of a hydroethanol extract and six polyphenol monomers from Morus alba L. (mulberry) twig. International Journal of Food Properties 20:sup2, pages 2207-2219.
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Amir Yarahmadi, Fatemeh Zal & Ayeh Bolouki. (2017) Protective effects of quercetin on nicotine induced oxidative stress in ‘HepG2 cells’. Toxicology Mechanisms and Methods 27:8, pages 609-614.
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Katrin Sak. (2014) Site-Specific Anticancer Effects of Dietary Flavonoid Quercetin. Nutrition and Cancer 66:2, pages 177-193.
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Ali H. Ad’hiah, Orooba N.H. Al-Bederi & Khulood W. Al-Sammarrae. (2013) Cytotoxic effects of Agrimonia eupatoria L. against cancer cell lines in vitro. Journal of the Association of Arab Universities for Basic and Applied Sciences 14:1, pages 87-92.
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KI WON LEE, HYONG JOO LEE & CHANG YONG LEE. (2004) Vitamins, Phytochemicals, Diets, and Their Implementation in Cancer Chemoprevention. Critical Reviews in Food Science and Nutrition 44:6, pages 437-452.
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Shwu-Yuann Lin, Shun-Jen Tsai, Lien-Hui Wang, Ming-Fang Wu & Huei Lee. (2002) Protection by Quercetin Against Cooking Oil Fumes-Induced DNA Damage in Human Lung Adenocarcinoma CL-3 Cells: Role of COX-2. Nutrition and Cancer 44:1, pages 95-101.
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Saura C. Sahu, Thomas J. Flynn, June A. Bradlaw, William L. Roth, Curtis N. Barton & James G. Yates. (2001) Pro-Oxidant Effects of the Flavonoid Myricetin on Rat Hepatocytes in Culture. Toxicology Methods 11:4, pages 277-283.
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Aliaa Ismail, Ebtesam El-Biyally & Wedad Sakran. (2023) An Innovative Approach for Formulation of Rutin Tablets Targeted for Colon Cancer Treatment. AAPS PharmSciTech 24:2.
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Motoko Morimoto, Ayaka Kato, Jin Kobayashi, Kei Okuda, Yoshikazu Kuwahara, Yasushi Kino, Yasuyuki Abe, Tsutomu Sekine, Tomokazu Fukuda, Emiko Isogai & Manabu Fukumoto. (2017) Gene expression analyses of the small intestine of pigs in the ex-evacuation zone of the Fukushima Daiichi Nuclear Power Plant. BMC Veterinary Research 13:1.
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Huey-Mei Shaw, Jhih-Ling Wu & Ming-Shyong Wang. (2017) Antihypertensive effects of Ocimum gratissimum extract: Angiotensin-converting enzyme inhibitor in vitro and in vivo investigation. Journal of Functional Foods 35, pages 68-73.
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Qing Guo, Shiyu Li, Yajie Xie, Qian Zhang, Mengge Liu, Zhenrui Xu, Hanxiao Sun & Yan Yang. (2017) The NAD + -dependent deacetylase, Bifidobacterium longum Sir2 in response to oxidative stress by deacetylating SigH (σ H ) and FOXO3a in Bifidobacterium longum and HEK293T cell respectively. Free Radical Biology and Medicine 108, pages 929-939.
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Mireille M.J.P.E. Sthijns, Paul M. Schiffers, Ger M. Janssen, Kristien J.A. Lemmens, Bart Ides, Philippe Vangrieken, Freek G. Bouwman, Edwin C. Mariman, Irina Pader, Elias S.J. Arnér, Katarina Johansson, Aalt Bast & Guido R.M.M. Haenen. (2017) Rutin protects against H 2 O 2 -triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress. Biochimica et Biophysica Acta (BBA) - General Subjects 1861:5, pages 1177-1189.
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Erminiana Daminani Mendonça, Juliana da Silva, Marcela S. dos Santos, Patricia Carvalho, Débora Kuck Mausolff Papke, Caroline Flach Ortmann, Jaqueline Nascimento Picada, Flávio Henrique Reginatto & Alexandre de Barros Falcão Ferraz. (2016) Genotoxic, mutagenic and antigenotoxic effects of Cecropia pachystachya Trécul aqueous extract using in vivo and in vitro assays. Journal of Ethnopharmacology 193, pages 214-220.
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Mehtap Tugce Ozkan, Rezzan Aliyazicioglu, Selim Demir, Sema Misir, Ibrahim Turan, Sermet Yildirmis & Yuksel Aliyazicioglu. (2016) Phenolic Characterisation and Antioxidant Activity of Primula vulgaris and Its Antigenotoxic Effect on Fibroblast Cells. Jundishapur Journal of Natural Pharmaceutical Products 12:1.
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Mehtap Tugce Ozkan, Rezzan Aliyazicioglu, Selim Demir, Sema Misir, Ibrahim Turan, Sermet Yildirmis & Yuksel Aliyazicioglu. (2016) Phenolic Characterisation and Antioxidant Activity of Primula vulgaris and Its Antigenotoxic Effect on Fibroblast Cells. Jundishapur Journal of Natural Pharmaceutical Products In press:In press.
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Hans Vergauwen, Sara Prims, Jeroen Degroote, Wei Wang, Christophe Casteleyn, Steven van Cruchten, Stefaan de Smet, Joris Michiels & Chris van Ginneken. (2016) In Vitro Investigation of Six Antioxidants for Pig Diets. Antioxidants 5:4, pages 41.
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Zoey Harris, Micah G. Donovan, Gisele Morais Branco, Kirsten H. Limesand & Randy Burd. (2016) Quercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development Strategy. Frontiers in Nutrition 3.
Crossref
Vlad Simon Luca, Anca Miron & Ana Clara Aprotosoaie. (2016) The antigenotoxic potential of dietary flavonoids. Phytochemistry Reviews 15:4, pages 591-625.
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Seda Tarhan, Filiz Özdemir, Zerrin İncesu & Emine Sütken Demirkan. (2015) Direct and protective effects of single or combined addition of vincristine and ε-viniferin on human HepG2 cellular oxidative stress markers in vitro. Cytotechnology 68:4, pages 1081-1094.
Crossref
Soumya Ganguly, Raghuvir H. Gaonkar, Samarendu Sinha, Amit Gupta, Dipankar Chattopadhyay, Sankha Chattopadhyay, Satbir S. Sachdeva, Shantanu Ganguly & Mita C. Debnath. (2016) Fabrication of surfactant-free quercetin-loaded PLGA nanoparticles: evaluation of hepatoprotective efficacy by nuclear scintigraphy. Journal of Nanoparticle Research 18:7.
Crossref
Ana Clara Aprotosoaie, Cosmin Teodor Mihai, Gabriela Vochita, Pincu Rotinberg, Adriana Trifan, Simon Vlad Luca, Tudor Petreus, Elvira Gille & Anca Miron. (2016) Antigenotoxic and antioxidant activities of a polyphenolic extract from European Dracocephalum moldavica L.. Industrial Crops and Products 79, pages 248-257.
Crossref
A. Brunori, C. Nobili & S. Procacci. 2016. Molecular Breeding and Nutritional Aspects of Buckwheat. Molecular Breeding and Nutritional Aspects of Buckwheat 219 227 .
Vanda Mendes, Rita Vilaça, Victor de Freitas, Pedro Moradas Ferreira, Nuno Mateus & Vítor Costa. (2015) Effect of Myricetin, Pyrogallol, and Phloroglucinol on Yeast Resistance to Oxidative Stress. Oxidative Medicine and Cellular Longevity 2015, pages 1-10.
Crossref
Vanda Mendes, Vítor Costa & Nuno Mateus. (2015) Involvement of the modulation of cancer cell redox status in the anti-tumoral effect of phenolic compounds. RSC Advances 5:1, pages 1-9.
Crossref
Oksana Sytar, Anatoliy Kosyan, Nataiya Taran & Iryna Smetanska. (2014) Anthocyanin’s as marker for selection of buckwheat plants with high rutin contentAnthocyane als Marker zur Selektion von Buchweizenpflanzen mit hohem Rutingehalt. Gesunde Pflanzen 66:4, pages 165-169.
Crossref
Shweta Thakur, Bibekananda Sarkar, Ravi P Cholia, Nandini Gautam, Monisha Dhiman & Anil K Mantha. (2014) APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions. Experimental & Molecular Medicine 46:7, pages e106-e106.
Crossref
Jeremy S. Barnes & Kevin A. Schug. (2014) Oxidative Degradation of Quercetin with Hydrogen Peroxide Using Continuous-Flow Kinetic Electrospray–Ion Trap–Time-of-Flight Mass Spectrometry. Journal of Agricultural and Food Chemistry 62:19, pages 4322-4331.
Crossref
JIA-LE SONG & YANG GAO. (2014) Effects of methanolic extract form Fuzhuan brick-tea on hydrogen peroxide-induced oxidative stress in human intestinal epithelial adenocarcinoma Caco-2 cells. Molecular Medicine Reports 9:3, pages 1061-1067.
Crossref
Shamala Salvamani, Baskaran Gunasekaran, Noor Azmi Shaharuddin, Siti Aqlima Ahmad & Mohd Yunus Shukor. (2014) Antiartherosclerotic Effects of Plant Flavonoids. BioMed Research International 2014, pages 1-11.
Crossref
Sebastião de O. Rebouças, Juliana da Silva, Ricardo S. Bertoni, Natalia Decker, Marcela Silva dos Santos, Raíssa R. Rossatto, Dione S. Corrêa & Alexandre B.F. Ferraz. (2013) Assessment of the genotoxic and mutagenic properties of Himatanthus articulatus bark extracts used as phytotherapeutic drug in the Amazon. Journal of Ethnopharmacology 147:2, pages 474-480.
Crossref
Karunrat Sakulnarmrat, Michael Fenech, Philip Thomas & Izabela Konczak. (2013) Cytoprotective and pro-apoptotic activities of native Australian herbs polyphenolic-rich extracts. Food Chemistry 136:1, pages 9-17.
Crossref
Yong Li & Ye Ding. (2012) Minireview: Therapeutic potential of myricetin in diabetes mellitus. Food Science and Human Wellness 1:1, pages 19-25.
Crossref
Ye DingZhao-Feng ZhangXiao-Qian DaiYong Li. (2012) Myricetin Protects Against Cytokine-Induced Cell Death in RIN-m5f β Cells. Journal of Medicinal Food 15:8, pages 733-740.
Crossref
Eduardo Madrigal-Santillán, Sonia Fragoso-Antonio, Carmen Valadez-Vega, Gloria Solano-Solano, Clara Zúñiga Pérez, Manuel Sánchez-Gutiérrez, Jeannett A. Izquierdo-Vega, José Gutiérrez-Salinas, Jaime Esquivel-Soto, César Esquivel-Chirino, Teresa Sumaya-Martínez, Tomas Fregoso-Aguilar, Jorge Mendoza-Pérez & José A. Morales-González. (2012) Investigation on the Protective Effects of Cranberry Against the DNA Damage Induced by Benzo[a]pyrene. Molecules 17:4, pages 4435-4451.
Crossref
So-Jin Choi, Bui Huu Tai, Nguyen Manh Cuong, Young-Ho Kim & Hae-Dong Jang. (2012) Antioxidative and anti-inflammatory effect of quercetin and its glycosides isolated from mampat (Cratoxylum formosum). Food Science and Biotechnology 21:2, pages 587-595.
Crossref
Napatr Sriraksa, Jintanaporn Wattanathorn, Supaporn Muchimapura, Somsak Tiamkao, Kamoltip Brown & Kowit Chaisiwamongkol. (2012) Cognitive-Enhancing Effect of Quercetin in a Rat Model of Parkinson's Disease Induced by 6-Hydroxydopamine. Evidence-Based Complementary and Alternative Medicine 2012, pages 1-9.
Crossref
Stalin Selvaraj, Sridharan Krishnaswamy, Venkappayya Devashya, Swaminathan Sethuraman & Uma Maheswari Krishnan. (2012) Synthesis, characterization and DNA binding properties of rutin–iron complex. RSC Advances 2:7, pages 2797.
Crossref
Ana Teresa Serra, Rui O. Duarte, Maria R. Bronze & Catarina M.M. Duarte. (2011) Identification of bioactive response in traditional cherries from Portugal. Food Chemistry 125:2, pages 318-325.
Crossref
Gyo-Nam Kim, Young-In Kwon & Hae-Dong Jang. (2011) Protective mechanism of quercetin and rutin on 2,2′-azobis(2-amidinopropane)dihydrochloride or Cu2+-induced oxidative stress in HepG2 cells. Toxicology in Vitro 25:1, pages 138-144.
Crossref
Pablo Blanco Martínez de Morentin, Carmen R González & Miguel López. (2010) AMP‐activated protein kinase: ‘a cup of tea’ against cholesterol‐induced neurotoxicity. The Journal of Pathology 222:4, pages 329-334.
Crossref
Jin Dai & Russell J. Mumper. (2010) Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties. Molecules 15:10, pages 7313-7352.
Crossref
Mark Feldman, Ervin I. Weiss, Itzhak Ofek, Moshe Shemesh & Doron Steinberg. (2010) In Vitro Real-Time Interactions of Cranberry Constituents with Immobilized Fructosyltransferase . Journal of Medicinal Food 13:5, pages 1153-1160.
Crossref
Sung Keun Jung, Ki Won Lee, Ho Young Kim, Mi Hyun Oh, Sanguine Byun, Sung Hwan Lim, Yong-Seok Heo, Nam Joo Kang, Ann M. Bode, Zigang Dong & Hyong Joo Lee. (2010) Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf. Biochemical Pharmacology 79:10, pages 1455-1461.
Crossref
Ann M. Bode & Zigang Dong. 2010. Bioactive Compounds and Cancer. Bioactive Compounds and Cancer 125 143 .
Pinar Oztopcu-Vatan, Selda Kabadere & Ruhi Uyar. (2009) The effect of pretreatment or combined treatment of quercetin on menadione toxicity in rat primary mixed glial cells in vitro. Cytotechnology 61:1-2, pages 11-16.
Crossref
Eileen Ryan, S. Aisling Aherne, Michael N. O'Grady, Laura McGovern, Joseph P. Kerry & Nora M. O'Brien. (2009) Bioactivity of Herb-Enriched Beef Patties. Journal of Medicinal Food 12:4, pages 893-901.
Crossref
Brahma N. Singh, B.R. Singh, R.L. Singh, D. Prakash, D.P. Singh, B.K. Sarma, G. Upadhyay & H.B. Singh. (2009) Polyphenolics from various extracts/fractions of red onion (Allium cepa) peel with potent antioxidant and antimutagenic activities. Food and Chemical Toxicology 47:6, pages 1161-1167.
Crossref
Yuan-Wei Shih, Pei-Fen Wu, Yi -Chieh Lee, Ming-Der Shi & Tai-An Chiang. (2009) Myricetin Suppresses Invasion and Migration of Human Lung Adenocarcinoma A549 Cells: Possible Mediation by Blocking the ERK Signaling Pathway. Journal of Agricultural and Food Chemistry 57:9, pages 3490-3499.
Crossref
Christopher D. Mann, Christopher P. Neal, Giuseppe Garcea, Margaret M. Manson, Ashley R. Dennison & David P. Berry. (2009) Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis. European Journal of Cancer Prevention 18:1, pages 13-25.
Crossref
S. Paoletta, G.B. Steventon, D. Wildeboer, T.M. Ehrman, P.J. Hylands & D.J. Barlow. (2008) Screening of herbal constituents for aromatase inhibitory activity. Bioorganic & Medicinal Chemistry 16:18, pages 8466-8470.
Crossref
Jiyun Ahn, Hyunjung Lee, Suna Kim, Jaeho Park & Taeyoul Ha. (2008) The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways. Biochemical and Biophysical Research Communications 373:4, pages 545-549.
Crossref
Yoko Sakanashi, Keisuke Oyama, Hiroko Matsui, Toshihisa B. Oyama, Tomohiro M. Oyama, Yumiko Nishimura, Hitomi Sakai & Yasuo Oyama. (2008) Possible use of quercetin, an antioxidant, for protection of cells suffering from overload of intracellular Ca2+: A model experiment. Life Sciences 83:5-6, pages 164-169.
Crossref
A.A. Ramos, C.F. Lima, M.L. Pereira, M. Fernandes-Ferreira & C. Pereira-Wilson. (2008) Antigenotoxic effects of quercetin, rutin and ursolic acid on HepG2 cells: Evaluation by the comet assay. Toxicology Letters 177:1, pages 66-73.
Crossref
A. R. Silva, A. M. Pinheiro, C. S. Souza, S. R. V.-B. Freitas, V. Vasconcellos, S. M. Freire, E. S. Velozo, M. Tardy, R. S. El-Bachá, M. F. D. Costa & S. L. Costa. (2007) The flavonoid rutin induces astrocyte and microglia activation and regulates TNF-alpha and NO release in primary glial cell cultures. Cell Biology and Toxicology 24:1, pages 75-86.
Crossref
G.F. Dire, M.F.M.C. Coura, M.C.L. Almeida, S.D.D. Vasconcelo, P.R.A. Siqueira, R.M. Duarte, J.S. Rodrigues, J.C.S. Oliveira, M.L. Fernandes & M. Bernardo-F. (2007) Study of the Effects of a Chayotte (Sechium edule) Extract on the Plasmid Puc. 9.1 DNA. Plant Pathology Journal 6:1, pages 72-76.
Crossref
Theresa A. Herring, Susan L. Cuppett & Janos Zempleni. (2007) Genomic Implications of H2O2 for Cell Proliferation and Growth of Caco-2 Cells. Digestive Diseases and Sciences 52:11, pages 3005-3015.
Crossref
A. Brunori & G. Végvári. (2007) Rutin content of the grain of buckwheat ( Fagopyrum esculentum Moench. and Fagopyrum tataricum Gaertn.) varieties growtn in southern Italy. Acta Agronomica Hungarica 55:3, pages 265-272.
Crossref
S. Aisling Aherne, Joseph P. Kerry & Nora M. O'Brien. (2007) Effects of plant extracts on antioxidant status and oxidant-induced stress in Caco-2 cells. British Journal of Nutrition 97:2, pages 321-328.
Crossref
C. Belloir, V. Singh, C. Daurat, M.H. Siess & A.M. Le Bon. (2006) Protective effects of garlic sulfur compounds against DNA damage induced by direct- and indirect-acting genotoxic agents in HepG2 cells. Food and Chemical Toxicology 44:6, pages 827-834.
Crossref
Ki Won Lee & Hyong Joo Lee. (2006) Biphasic effects of dietary antioxidants on oxidative stress-mediated carcinogenesis. Mechanisms of Ageing and Development 127:5, pages 424-431.
Crossref
Ki Won Lee & Hyong Joo Lee. (2006) The roles of polyphenols in cancer chemoprevention. BioFactors 26:2, pages 105-121.
Crossref
Mario Alía, Sonia Ramos, Raquel Mateos, Laura Bravo & Luis Goya. (2005) Response of the antioxidant defense system to tert ‐butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2) . Journal of Biochemical and Molecular Toxicology 19:2, pages 119-128.
Crossref
Evgeny Denisov & Igor Afanas’ev. 2005. Oxidation and Antioxidants in Organic Chemistry and Biology. Oxidation and Antioxidants in Organic Chemistry and Biology 1 284 .
Yesennia Sánchez-Pérez, Claudia Carrasco-Legleu, Claudia García-Cuellar, Julio Pérez-Carreón, Sergio Hernández-García, Martha Salcido-Neyoy, Leticia Alemán-Lazarini & Saúl Villa-Treviño. (2005) Oxidative stress in carcinogenesis. Correlation between lipid peroxidation and induction of preneoplastic lesions in rat hepatocarcinogenesis. Cancer Letters 217:1, pages 25-32.
Crossref
Raquel Mateos, Luis Goya & Laura Bravo. (2004) Determination of malondialdehyde by liquid chromatography as the 2,4-dinitrophenylhydrazone derivative. Journal of Chromatography B 805:1, pages 33-39.
Crossref
Niurka Llópiz, Francesc Puiggròs, Ela Céspedes, Lluís Arola, Anna Ardévol, Cinta Bladé & M. Josepa Salvadó. (2004) Antigenotoxic Effect of Grape Seed Procyanidin Extract in Fao Cells Submitted to Oxidative Stress. Journal of Agricultural and Food Chemistry 52:5, pages 1083-1087.
Crossref
Pattipati S. Naidu, Amanpreet Singh & Shrinivas K. Kulkarni. (2004) Reversal of Reserpine-Induced Orofacial Dyskinesia and Cognitive Dysfunction by Quercetin. Pharmacology 70:2, pages 59-67.
Crossref
Felicia Rivera, Jessika Urbanavicius, Elena Gervaz, Andrea Morquio & Federico Dajas. (2004) Some aspects of thein vivo neuroprotective capacity of flavonoids: Bioavailability and structure-activity relationship. Neurotoxicity Research 6:7-8, pages 543-553.
Crossref
Pattipati S. Naidu, Amanpreet Singh & Shrinivas K. Kulkarni. (2003) Quercetin, a bioflavonoid, attenuates haloperidol-induced orofacial dyskinesia. Neuropharmacology 44:8, pages 1100-1106.
Crossref
Pattipati S. Naidu, Amanpreet Singh & Shrinivas K. Kulkarni. (2003) Reversal of haloperidol-induced orofacial dyskinesia by quercetin, a bioflavonoid. Psychopharmacology 167:4, pages 418-423.
Crossref
David Turgeon, Jean-Sébastien Carrier, Sarah Chouinard & Alain Bélanger. (2003) Glucuronidation Activity of the UGT2B17 Enzyme toward Xenobiotics. Drug Metabolism and Disposition 31:5, pages 670-676.
Crossref
Małgorzata Zielińska, Michael Gülden & Hasso Seibert. (2003) Effects of quercetin and quercetin-3-O-glycosides on oxidative damage in rat C6 glioma cells. Environmental Toxicology and Pharmacology 13:1, pages 47-53.
Crossref
Tair Lapidot, Michael D. Walker & Joseph Kanner. (2002) Antioxidant and Prooxidant Effects of Phenolics on Pancreatic β-Cells in Vitro. Journal of Agricultural and Food Chemistry 50:25, pages 7220-7225.
Crossref
Fredrik Ollila, Katrin Halling, Pia Vuorela, Heikki Vuorela & J.Peter Slotte. (2002) Characterization of Flavonoid–Biomembrane Interactions. Archives of Biochemistry and Biophysics 399:1, pages 103-108.
Crossref
J.A. Woods, C. Jewell & N.M. O'Brien. (2001) Sedanolide, a Natural Phthalide from Celery Seed Oil: Effect on Hydrogen Peroxide and tert -Butyl Hydroperoxide-Induced Toxicity in HepG2 and CaCo-2 Human Cell Lines . In Vitro & Molecular Toxicology 14:3, pages 233-240.
Crossref
Charles S. Bestwick & Lesley Milne. (2001) Quercetin modifies reactive oxygen levels but exerts only partial protection against oxidative stress within HL-60 cells. Biochimica et Biophysica Acta (BBA) - General Subjects 1528:1, pages 49-59.
Crossref
H Babich & H.L Zuckerbraun. (2001) In vitro cytotoxicity of glyco-S-nitrosothiols. Toxicology in Vitro 15:3, pages 181-190.
Crossref
Junichi HIRAYAMA, Stephen J. WAGNER, Hideki ABE, Kenji IKEBUCHI & Hisami IKEDA. (2001) Involvement of Reactive Oxygen Species in Hemoglobin Oxidation and Virus Inactivation by 1,9-Dimethylmethylene Blue Phototreatment.. Biological and Pharmaceutical Bulletin 24:4, pages 418-421.
Crossref
Melissa R. Kelly, Cissy M. Geigerman & George Loo. (2001) Epigallocatechin gallate protects U937 cells against nitric oxide-induced cell cycle arrest and apoptosis. Journal of Cellular Biochemistry 81:4, pages 647-658.
Crossref
Sharon A. Aherne & Nora M. O’Brien. (2000) Mechanism of protection by the flavonoids, quercetin and rutin, against tert-butylhydroperoxide- and menadione-induced DNA single strand breaks in Caco-2 cells. Free Radical Biology and Medicine 29:6, pages 507-514.
Crossref

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