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Original Articles

Role of Nitric Oxide and Peroxynitrite in Bile Salt-Induced Apoptosis: Relevance to Colon Carcinogenesis

Pages 180-188 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Ahmet Uyar, Abdulahad Doğan, Turan Yaman, Ömer Faruk Keleş, Zabit Yener, İsmail Çelik & Elif Ebru Alkan. (2022) The Protective Role of Urtica dioica Seed Extract Against Azoxymethane-Induced Colon Carcinogenesis in Rats. Nutrition and Cancer 74:1, pages 306-319.
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Claire M Payne, Hana Holubec, Cheray Crowley-Skillicorn, Huy Nguyen, Harris Bernstein, George Wilcox & Carol Bernstein. (2011) Maspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis. Clinical and Experimental Gastroenterology 4, pages 239-253.
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Claire M Payne, Cheray Crowley-Skillicorn, Carol Bernstein, Hana Holubec & Harris Bernstein. (2011) Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. Clinical and Experimental Gastroenterology 4, pages 75-119.
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ClaireM. Payne, Cheray Crowley-Skillicorn, Carol Bernstein, Hana Holubec, Mary Pat Moyer & Harris Bernstein. (2010) Hydrophobic Bile Acid-Induced Micronuclei Formation, Mitotic Perturbations, and Decreases in Spindle Checkpoint Proteins: Relevance to Genomic Instability in Colon Carcinogenesis. Nutrition and Cancer 62:6, pages 825-840.
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Claire M Payne, Carol Bernstein, Katerina Dvorak & Harris Bernstein. (2008) Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis. Clinical and Experimental Gastroenterology 1, pages 19-47.
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Stan A.B. Greenacre & Harry Ischiropoulos. (2001) Tyrosine nitration: Localisation, quantification, consequences for protein function and signal transduction. Free Radical Research 34:6, pages 541-581.
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Articles from other publishers (24)

Bene A. Ekine-Afolabi, Anoka A. Njan, Solomon O. Rotimi, Anu R. I.Attia M. Elbehi, Elizabeth Cash & Ademola Adeyeye. (2020) The Impact of Diet on the Involvement of Non-Coding RNAs, Extracellular Vesicles, and Gut Microbiome-Virome in Colorectal Cancer Initiation and Progression. Frontiers in Oncology 10.
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Seyhan Sahan-Firat, Meryem Temiz-Resitoglu, Demet Sinem Guden, Sefika Pinar Kucukkavruk, Bahar Tunctan, Ayse Nihal Sari, Zumrut Kocak & Kafait U. Malik. (2017) Protection by mTOR Inhibition on Zymosan-Induced Systemic Inflammatory Response and Oxidative/Nitrosative Stress: Contribution of mTOR/MEK1/ERK1/2/IKKβ/IκB-α/NF-κB Signalling Pathway. Inflammation 41:1, pages 276-298.
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Salvatore De Maria, Ilaria Scognamiglio, Angela Lombardi, Nicola Amodio, Michele Caraglia, Maria Cartenì, Gianpietro Ravagnan & Paola Stiuso. (2013) Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell. Journal of Translational Medicine 11:1.
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Jun-tang Li, Hui Wang, Wei Li, Li-feng Wang, Li-chao Hou, Jing-lan Mu, Xin Liu, Hui-juan Chen, Ke-lang Xie, Nan-lin Li & Chun-fang Gao. (2013) Anesthetic Isoflurane Posttreatment Attenuates Experimental Lung Injury by Inhibiting Inflammation and Apoptosis. Mediators of Inflammation 2013, pages 1-16.
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Carol Bernstein, Hana Holubec, Achyut K. Bhattacharyya, Huy Nguyen, Claire M. Payne, Beryl Zaitlin & Harris Bernstein. (2011) Carcinogenicity of deoxycholate, a secondary bile acid. Archives of Toxicology 85:8, pages 863-871.
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Rosanna D I Paola, Giacomo Oteri, Emanuela Mazzon, Concetta Crisafulli, Maria Galuppo, Roberto D A L Toso, Giovanna Pressi, Giancarlo Cordasco & Salvatore Cuzzocrea. (2011) Effects of verbascoside, biotechnologically purified by Syringa vulgaris plant cell cultures, in a rodent model of periodontitis . Journal of Pharmacy and Pharmacology 63:5, pages 707-717.
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Subapriya Rajamanickam, Manjinder Kaur, Balaiya Velmurugan, Rana P. Singh & Rajesh Agarwal. (2009) Silibinin Suppresses Spontaneous Tumorigenesis in APC min/+ Mouse Model by Modulating Beta-Catenin Pathway. Pharmaceutical Research 26:12, pages 2558-2567.
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Harris Bernstein, Carol Bernstein, Claire M Payne & Katerina Dvorak. (2009) Bile acids as endogenous etiologic agents in gastrointestinal cancer. World Journal of Gastroenterology 15:27, pages 3329.
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Claire M. Payne, Cheray Crowley-Skillicorn, Hana Holubec, Katerina Dvorak, Carol Bernstein, Mary Pat Moyer, Harinder Garewal & Harris Bernstein. (2009) Deoxycholate, an Endogenous Cytotoxin/Genotoxin, Induces the Autophagic Stress-Survival Pathway: Implications for Colon Carcinogenesis. Journal of Toxicology 2009, pages 1-14.
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Brian T. Bucher, Xuesheng Feng, Geetha Jeyabalan, Baochun Zhang, Lifang Shao, Zhong Guo & David A. Geller. (2007) Glycochenodeoxycholate (GCDC) Inhibits Cytokine Induced iNOS Expression in Rat Hepatocytes. Journal of Surgical Research 138:1, pages 15-21.
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He Wang & James Leigh. (2006) Effects of nitric oxide synthase inhibitor ω-Nitro-L-Arginine Methyl Ester, on silica-induced inflammatory reaction and apoptosis. Particle and Fibre Toxicology 3:1.
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Hagit F. Yerushalmi, David G. Besselsen, Natalia A. Ignatenko, Karen A. Blohm-Mangone, Jose L. Padilla-Torres, David E. Stringer, Haiyan Cui, Hana Holubec, Claire M. Payne & Eugene W. Gerner. (2006) The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis. Molecular Carcinogenesis 45:2, pages 93-105.
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C. M. Payne, C. L. Crowley-Weber, K. Dvorak, C. Bernstein, H. Bernstein, H. Holubec, C. Crowley & H. Garewal. (2005) Mitochondrial perturbation attenuates bile acid-induced cytotoxicity. Cell Biology and Toxicology 21:5-6, pages 215-231.
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H. Bernstein, C. Bernstein, C.M. Payne, K. Dvorakova & H. Garewal. (2005) Bile acids as carcinogens in human gastrointestinal cancers. Mutation Research/Reviews in Mutation Research 589:1, pages 47-65.
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Mark M. Huycke & H. Rex Gaskins. (2016) Commensal Bacteria, Redox Stress, and Colorectal Cancer: Mechanisms and Models. Experimental Biology and Medicine 229:7, pages 586-597.
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Harris Bernstein, Claire M. Payne, Kathleen Kunke, Cara L. Crowley-Weber, Caroline N. Waltmire, Katerina Dvorakova, Hana Holubec, Carol Bernstein, Richard R. Vaillancourt, Deborah A. Raynes, Vincent Guerriero & Harinder Garewal. (2004) A proteomic study of resistance to deoxycholate-induced apoptosis. Carcinogenesis 25:5, pages 681-692.
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Michael Trauner. (2003) When bile ducts say NO: The good, the bad, and the ugly. Gastroenterology 124:3, pages 847-851.
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Cara L Crowley-Weber, Katerina Dvorakova, Cheray Crowley, Harris Bernstein, Carol Bernstein, Harinder Garewal & Claire M Payne. (2003) Nicotine increases oxidative stress, activates NF-κB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis. Chemico-Biological Interactions 145:1, pages 53-66.
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Delon Washo-Stultz, Cara L Crowley-Weber, Katerina Dvorakova, Carol Bernstein, Harris Bernstein, Kathleen Kunke, Caroline N Waltmire, Harinder Garewal & Claire M Payne. (2002) Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis. Cancer Letters 177:2, pages 129-144.
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Claire M. Payne, Harris Bernstein, Carol Bernstein, Kathleen Kunke & Harinder Garewal. (2001) The Specific NOS2 Inhibitor, 1400W, Sensitizes HepG2 Cells to Genotoxic, Oxidative, Xenobiotic, and Endoplasmic Reticulum Stresses. Antioxidants & Redox Signaling 3:5, pages 931-936.
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Young-Joon Surh, Kyung-Soo Chun, Hyun-Ho Cha, Seong Su Han, Young-Sam Keum, Kwang-Kyun Park & Sang Sup Lee. (2001) Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-κB activation. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 480-481, pages 243-268.
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Peter K.M Kim, Ruben Zamora, Patricia Petrosko & Timothy R Billiar. (2001) The regulatory role of nitric oxide in apoptosis. International Immunopharmacology 1:8, pages 1421-1441.
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Richard A. Oeckler & Michael S. Wolin. (2000) New concepts in vascular nitric oxide signaling. Current Atherosclerosis Reports 2:5, pages 437-444.
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Delon Washo-Stultz, Cara Crowley, Claire M Payne, Carol Bernstein, Sarah Marek, Eugene W Gerner & Harris Bernstein. (2000) Increased susceptibility of cells to inducible apoptosis during growth from early to late log phase: an important caveat for in vitro apoptosis research. Toxicology Letters 116:3, pages 199-207.
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