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Original Articles

Cruciferous Vegetables, Genetic Polymorphisms in Glutathione S-Transferases M1 and T1, and Prostate Cancer Risk

Pages 206-213 | Published online: 18 Nov 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Maria Russo, Carmela Spagnuolo, Gian Luigi Russo, Krystyna Skalicka-Woźniak, Maria Daglia, Eduardo Sobarzo-Sánchez, Seyed Fazel Nabavi & Seyed Mohammad Nabavi. (2018) Nrf2 targeting by sulforaphane: A potential therapy for cancer treatment. Critical Reviews in Food Science and Nutrition 58:8, pages 1391-1405.
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Michael F Leitzmann & Sabine Rohrmann. (2012) Risk factors for the onset of prostatic cancer: age, location, and behavioral correlates. Clinical Epidemiology 4, pages 1-11.
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Huawei Zeng, OliviaN. Trujillo, MaryP. Moyer & JamesH. Botnen. (2011) Prolonged Sulforaphane Treatment Activates Survival Signaling in Nontumorigenic NCM460 Colon Cells but Apoptotic Signaling in Tumorigenic HCT116 Colon Cells. Nutrition and Cancer 63:2, pages 248-255.
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Daniel R McGrath, Hamid Frydoonfar, Joshua J Hunt, Chris J Dunkley & Allan D Spigelman. (2010) Serum glutathione transferase does not respond to indole-3-carbinol: A pilot study. Therapeutics and Clinical Risk Management 6, pages 225-231.
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JohnE. Lewis, Hosanna Soler-Vilá, PeterE. Clark, LauraA. Kresty, GlennO. Allen & JenniferJ. Hu. (2009) Intake of Plant Foods and Associated Nutrients in Prostate Cancer Risk. Nutrition and Cancer 61:2, pages 216-224.
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Daniel R McGrath & Allan D Spigelman. (2008) Putative mechanisms of action for indole-3-carbinol in the prevention of colorectal cancer. Expert Opinion on Therapeutic Targets 12:6, pages 729-738.
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EricC. Nelson, RaymondL. Rodriguez, Kevin Dawson, AlfredoF. Galvez & ChristopherP. Evans. (2008) The Interaction of Genetic Polymorphisms With Lifestyle Factors: Implications for the Dietary Prevention of Prostate Cancer. Nutrition and Cancer 60:3, pages 301-312.
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Chunfang Li , Hao Liang , Qipeng Yuan & Xiaodan Hou. (2008) Optimization of Sulforaphane Separation from Broccoli Seeds by Macroporous Resins. Separation Science and Technology 43:3, pages 609-623.
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G. Sarıkamış, A. Balkaya & R. Yanmaz. (2008) Glucosinolates in Kale Genotypes from the Blacksea Region of Turkey. Biotechnology & Biotechnological Equipment 22:4, pages 942-946.
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Eun-Sun Hwang & PhyllisE. Bowen. (2007) DNA Damage, a Biomarker of Carcinogenesis: Its Measurement and Modulation by Diet and Environment. Critical Reviews in Food Science and Nutrition 47:1, pages 27-50.
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Susan E. McCann, Christine B. Ambrosone, Kirsten B. Moysich, John Brasure, James R. Marshall, Jo L. Freudenheim, Gregg S. Wilkinson & Saxon Graham. (2005) Intakes of Selected Nutrients, Foods, and Phytochemicals and Prostate Cancer Risk in Western New York . Nutrition and Cancer 53:1, pages 33-41.
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Articles from other publishers (137)

Hidde P. van Steenwijk, Evi Winter, Edward Knaven, Jos F. Brouwers, Myrthe van Baardwijk, Jasper B. van Dalum, Teus J. C. Luijendijk, Frits H. M. van Osch, Freddy J. Troost, Aalt Bast, Khrystyna O. Semen & Alie de Boer. (2023) The beneficial effect of sulforaphane on platelet responsiveness during caloric load: a single-intake, double-blind, placebo-controlled, crossover trial in healthy participants. Frontiers in Nutrition 10.
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Mohamed J. Saadh, Roxana Yolanda Castillo-Acobo, Hala Baher, Jayasankar Narayanan, Jessica Paola Palacios Garay, Michelle Naomi Vera Yamaguchi, José Luis Arias Gonzáles, Juan Carlos Cotrina-Aliaga, Shaik Vaseem Akram, Natrayan Lakshmaiya, Ali H. Amin, Mohamed Mohany, Salim S. Al-Rejaie, Muhammad Ahsan, Abolfazl Bahrami & Reza Akhavan-Sigari. (2023) The protective role of sulforaphane and Homer1a in retinal ischemia-reperfusion injury: Unraveling the neuroprotective interplay. Life Sciences, pages 121968.
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Demet Saylan & Fatma Cebeci. 2023. Multidisciplinary Applications of Natural Science for Drug Discovery and Integrative Medicine. Multidisciplinary Applications of Natural Science for Drug Discovery and Integrative Medicine 22 60 .
Jiaye Long, Zhaohui Liu, Shuai Liang & Baoxiang Chen. (2023) Cruciferous Vegetable Intake and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis. Urologia Internationalis 107:7, pages 723-733.
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Łukasz Janczewski. (2022) Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity. Molecules 27:5, pages 1750.
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Iahtisham‐Ul‐Haq, Sipper Khan, Kanza Aziz Awan & Muhammad Jawad Iqbal. (2021) Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review. Journal of Food Biochemistry 46:3.
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Lucia Aronica, Jose M. Ordovas, Andrey Volkov, Joseph J. Lamb, Peter Michael Stone, Deanna Minich, Michelle Leary, Monique Class, Dina Metti, Ilona A. Larson, Nikhat Contractor, Brent Eck & Jeffrey S. Bland. (2022) Genetic Biomarkers of Metabolic Detoxification for Personalized Lifestyle Medicine. Nutrients 14:4, pages 768.
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Melissa García-Caballero, José Antonio Torres-Vargas, Ana Dácil Marrero, Beatriz Martínez-Poveda, Miguel Ángel Medina & Ana R. Quesada. (2022) Angioprevention of Urologic Cancers by Plant-Derived Foods. Pharmaceutics 14:2, pages 256.
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Marija Petkovic, Ermelindo C Leal, Ines Alves, Chanda Bose, Philip T Palade, Preeti Singh, Sanjay Awasthi, Elisabet Børsheim, Louise T Dalgaard, Sharda P Singh & Eugenia Carvalho. (2021) Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway. The Journal of Nutritional Biochemistry 98, pages 108817.
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Mirko Marino, Daniela Martini, Samuele Venturi, Massimiliano Tucci, Marisa Porrini, Patrizia Riso & Cristian Del Bo'. (2021) An Overview of Registered Clinical Trials on Glucosinolates and Human Health: The Current Situation. Frontiers in Nutrition 8.
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Lu Tong, Shanhan Cheng, Honghao Lv, Chengzhi Zhao, Jie Zhu, Pingwu Liu, Zhiwei Wang, Limei Yang & Yangyong Zhang. (2021) Analysis of Glucosinolate Content, Composition and Expression Level of Biosynthesis Pathway Genes in Different Chinese Kale Varieties. Horticulturae 7:10, pages 398.
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Anna E. Kaiser, Mojdeh Baniasadi, Derrek Giansiracusa, Matthew Giansiracusa, Michael Garcia, Zachary Fryda, Tin Lok Wong & Anupam Bishayee. (2021) Sulforaphane: A Broccoli Bioactive Phytocompound with Cancer Preventive Potential. Cancers 13:19, pages 4796.
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Km Anjaly & A. B. Tiku. (2021) MicroRNA mediated therapeutic effects of natural agents in prostate cancer. Molecular Biology Reports 48:7, pages 5759-5773.
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Christopher M. Harris, Kristen E. Zamperoni, Samantha C. Sernoskie, Natalie S.M. Chow & Thomas E. Massey. (2021) Effects of in vivo treatment of mice with sulforaphane on repair of DNA pyridyloxylbutylation. Toxicology 454, pages 152753.
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Osama A. Elkashty & Simon D. Tran. (2021) Sulforaphane as a Promising Natural Molecule for Cancer Prevention and Treatment. Current Medical Science 41:2, pages 250-269.
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Eun-Ryeong Hahm, Krishna B. Singh, Su-Hyeong Kim, Anna A. Powolny & Shivendra V. Singh. (2020) The Role of Lysosome-associated Membrane Protein 2 in Prostate Cancer Chemopreventive Mechanisms of Sulforaphane. Cancer Prevention Research 13:8, pages 661-672.
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Dominika Kuran, Anna Pogorzelska & Katarzyna Wiktorska. (2020) Breast Cancer Prevention-Is there a Future for Sulforaphane and Its Analogs?. Nutrients 12:6, pages 1559.
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Débora Villaño, Maria Teresa López-Chillón, Pilar Zafrilla & Diego A. Moreno. (2019) Bioavailability of broccoli sprouts in different human overweight populations. Journal of Functional Foods 59, pages 337-344.
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Jie Zhang, Chunrong Feng, Xuemei Tan, Peter-Leon Hagedoorn, Changhong Gu, Hui Xu & Xing Zhou. (2019) Effect of aliphatic diamine spacer length on enzymatic performance of myrosinase immobilized on chitosan microsphere and its application for sulforaphene production. Journal of Biotechnology 299, pages 79-85.
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Maria H Traka, Antonietta Melchini, Jack Coode-Bate, Omar Al Kadhi, Shikha Saha, Marianne Defernez, Perla Troncoso-Rey, Helen Kibblewhite, Carmel M O'Neill, Federico Bernuzzi, Laura Mythen, Jackie Hughes, Paul W Needs, Jack R Dainty, George M Savva, Robert D Mills, Richard Y Ball, Colin S Cooper & Richard F Mithen. (2019) Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention—results from the Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE) randomized controlled trial. The American Journal of Clinical Nutrition 109:4, pages 1133-1144.
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