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Ryutaro Utsumi. (2017) Bacterial signal transduction networks via connectors and development of the inhibitors as alternative antibiotics. Bioscience, Biotechnology, and Biochemistry 81:9, pages 1663-1669.
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Yuan-Chao Lou, Tsai-Hsuan Weng, Yi-Chuan Li, Yi-Fen Kao, Wei-Feng Lin, Hwei-Ling Peng, Shan-Ho Chou, Chwan-Deng Hsiao & Chinpan Chen. (2015) Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA. Nature Communications 6:1.
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Mikhail Metelev, Jonathan I. Tietz, Joel O. Melby, Patricia M. Blair, Lingyang Zhu, Itamar Livnat, Konstantin Severinov & Douglas A. Mitchell. (2015) Structure, Bioactivity, and Resistance Mechanism of Streptomonomicin, an Unusual Lasso Peptide from an Understudied Halophilic Actinomycete. Chemistry & Biology 22:2, pages 241-250.
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Kyle J. Wayne, Shuo Li, Krystyna M. Kazmierczak, Ho-Ching T. Tsui & Malcolm E. Winkler. (2012)
Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross-talk in
Streptococcus pneumoniae
D39 cells
. Molecular Microbiology 86:3, pages 645-660.
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Takafumi Watanabe, Masayuki Igarashi, Toshihide Okajima, Eiji Ishii, Hirokazu Kino, Masaki Hatano, Ryuichi Sawa, Maya Umekita, Tomoyuki Kimura, Sho Okamoto, Yoko Eguchi, Yuzuru Akamatsu & Ryutaro Utsumi. (2012) Isolation and Characterization of Signermycin B, an Antibiotic That Targets the Dimerization Domain of Histidine Kinase WalK. Antimicrobial Agents and Chemotherapy 56:7, pages 3657-3663.
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Ryutaro Utsumi & Masayuki Igarashi. (2012) Two-component Signal Transduction as Attractive Drug Targets in Pathogenic Bacteria病原細菌に対する新しい薬剤標的─二成分情報伝達システム. YAKUGAKU ZASSHI 132:1, pages 51-58.
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Benjamin P. Howden, Christopher R. E. McEvoy, David L. Allen, Kyra Chua, Wei Gao, Paul F. Harrison, Jan Bell, Geoffrey Coombs, Vicki Bennett-Wood, Jessica L. Porter, Roy Robins-Browne, John K. Davies, Torsten Seemann & Timothy P. Stinear. (2011) Evolution of Multidrug Resistance during Staphylococcus aureus Infection Involves Mutation of the Essential Two Component Regulator WalKR. PLoS Pathogens 7:11, pages e1002359.
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Nicola Horstmann, Pranoti Sahasrabhojane, Bryce Suber, Muthiah Kumaraswami, Randall J. Olsen, Anthony Flores, James M. Musser, Richard G. Brennan & Samuel A. Shelburne. (2011) Distinct Single Amino Acid Replacements in the Control of Virulence Regulator Protein Differentially Impact Streptococcal Pathogenesis. PLoS Pathogens 7:10, pages e1002311.
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