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Original Articles

Effects of Lotus Root (the Edible Rhizome of Nelumbo nucifera) on the Deveolopment of Non-Alcoholic Fatty Liver Disease in Obese Diabetic db/db Mice

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Pages 462-466 | Received 04 Oct 2011, Accepted 28 Nov 2011, Published online: 22 May 2014

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Zaida Zakaria, Zaidatul Akmal Othman, Victor Udo Nna & Mahaneem Mohamed. (2023) The promising roles of medicinal plants and bioactive compounds on hepatic lipid metabolism in the treatment of non-alcoholic fatty liver disease in animal models: molecular targets. Archives of Physiology and Biochemistry 129:6, pages 1262-1278.
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Guilin Chen, Mingzhi Zhu & Mingquan Guo. (2019) Research advances in traditional and modern use of Nelumbo nucifera: phytochemicals, health promoting activities and beyond. Critical Reviews in Food Science and Nutrition 59:sup1, pages S189-S209.
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Articles from other publishers (22)

Xu Zhao, Ran Zhao, Xiaojing Yang, Lihui Sun, Yongming Bao, Yuan Shuai Liu, Andreas Blennow & Xingxun Liu. (2023) Recent advances on bioactive compounds, biosynthesis mechanism, and physiological functions of Nelumbo nucifera. Food Chemistry 412, pages 135581.
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Jingfang Li, Ting Luo, Xiaoping Li, Xiaoru Liu & Ze-yuan Deng. (2023) Comparison of fresh and browning lotus roots (Nelumbo nucifera Gaertn.) on modulating cholesterol metabolism via decreasing hepatic cholesterol deposition and increasing fecal bile acid excretion. Current Research in Food Science 7, pages 100630.
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Akira Iwamoto, Ryoko Yamauchi, Shigeki Oogai, Yumi Tsuruta, Tsuge Keisuke, Yasuo Nagata & Teruyoshi Yanagita. (2022) Lotus root extract inhibits skin damage through suppression of collagenase production in vitro. Cytotechnology 74:2, pages 309-317.
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Sung Min Kim, Eun-Jung Park, Jong-Yeon Kim, Jihee Choi & Hae-Jeung Lee. (2020) Anti-Inflammatory Effects of Fermented Lotus Root and Linoleic Acid in Lipopolysaccharide-Induced RAW 264.7 Cells. Life 10:11, pages 293.
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Haq Nawaz, Aqsa Akbar, Hina Andaleeb, Mohibullah Shah, Adnan Amjad, Arif Mehmood & Rabia Mannan. (2020) Microwave-Induced Modification in Physical and Functional Characteristics and Antioxidant Potential of Nelumbo nucifera Rhizome Starch. Journal of Polymers and the Environment 28:11, pages 2965-2976.
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Gongji Liu, Yanzhao Liu, Shoulei Yan & Jie Li. (2020) Acetic acid reducing the softening of lotus rhizome during heating by regulating the chelate-soluble polysaccharides. Carbohydrate Polymers 240, pages 116209.
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Motonori Takagi, Maki Goto, David Wari, Tetsuro Kashima & Koki Toyota. (2019) Seasonal occurrence and life cycle of lotus root nematode Hirschmanniella diversa (Tylenchida: Pratylenchidae) in lotus roots in paddy fields. Applied Entomology and Zoology 54:4, pages 465-471.
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Brandon Perumpail, Andrew Li, Umair Iqbal, Sandy Sallam, Neha Shah, Waiyee Kwong, George Cholankeril, Donghee Kim & Aijaz Ahmed. (2018) Potential Therapeutic Benefits of Herbs and Supplements in Patients with NAFLD. Diseases 6:3, pages 80.
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Yuanyuan Zheng, Tiantian Liu, Zhiqiang Wang, Yang Xu, Quanbin Zhang & Dali Luo. (2018) Low molecular weight fucoidan attenuates liver injury via SIRT1/AMPK/PGC1α axis in db/db mice. International Journal of Biological Macromolecules 112, pages 929-936.
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Jarukitt Limwachiranon, Hao Huang, Zhenghan Shi, Li Li & Zisheng Luo. (2018) Lotus Flavonoids and Phenolic Acids: Health Promotion and Safe Consumption Dosages. Comprehensive Reviews in Food Science and Food Safety 17:2, pages 458-471.
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Hong-Xun Wang, Yang Yi, Jie Sun, Olusola Lamikanra & Ting Min. (2018) Fingerprint profiling of polysaccharides from different parts of lotus root varieties. RSC Advances 8:30, pages 16574-16584.
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Alaganandam Kumaran, Cheng Chang Ho & Lucy Sun Hwang. (2018) Protective effect of Nelumbo nucifera extracts on beta amyloid protein induced apoptosis in PC12 cells, in vitro model of Alzheimer's disease. Journal of Food and Drug Analysis 26:1, pages 172-181.
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Cheng Cheng, Ronghui Guo, Jianwu Lan, Shouxiang Jiang, Zoufei Du, Ludan Zhao & Linghui Peng. (2017) Effects of sodium hydroxide treatment on microstructure and mechanical properties of lotus fibers. Fibers and Polymers 18:9, pages 1671-1678.
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Zhen-Jie Zhuang, Chao-Wen Shan, Bo Li, Min-Xia Pang, Han Wang, Yan Luo, Yin-lan Liu, Yu Song, Nan-Nan Wang, Su-Hong Chen, Jun-ping Shi & Gui-Yuan Lv. (2017) Linarin Enriched Extract Attenuates Liver Injury and Inflammation Induced by High-Fat High-Cholesterol Diet in Rats. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-9.
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Bhesh Raj Sharma, Lekh Nath S. Gautam, Deepak Adhikari & Rajendra Karki. (2017) A Comprehensive Review on Chemical Profiling of Nelumbo Nucifera : Potential for Drug Development . Phytotherapy Research 31:1, pages 3-26.
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Yang Yi, Jie Sun, Jun Xie, Ting Min, Li-Mei Wang & Hong-Xun Wang. (2016) Phenolic Profiles and Antioxidant Activity of Lotus Root Varieties. Molecules 21:7, pages 863.
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T. K. LimT. K. Lim. 2016. Edible Medicinal and Non-Medicinal Plants. Edible Medicinal and Non-Medicinal Plants 55 109 .
Fengyan Li & Hongjun Fu. (2018) Effect of Alkaline Degumming on Structure and Properties of Lotus Fibers at Different Growth Period. Journal of Engineered Fibers and Fabrics 10:1, pages 155892501501000.
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Jeong Soon You, Yun Ju Lee, Kyoung Soo Kim, Sung Hoon Kim & Kyung Ja Chang. (2014) Ethanol extract of lotus (Nelumbo nucifera) root exhibits an anti-adipogenic effect in human pre-adipocytes and anti-obesity and anti-oxidant effects in rats fed a high-fat diet. Nutrition Research 34:3, pages 258-267.
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Ravirajsinh Jadeja, Ranjitsinh V. Devkar & Srinivas Nammi. (2014) Herbal Medicines for the Treatment of Nonalcoholic Steatohepatitis: Current Scenario and Future Prospects. Evidence-Based Complementary and Alternative Medicine 2014, pages 1-18.
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A-Rang Im, Young-Hwa Kim, Md. Romij Uddin, Seong Wook Chae, Hye Won Lee, Woo Suk Jung, Yun Hee Kim, Bong Ju Kang, Yeong Shik Kim & Mi-Young Lee. (2013) Protection from antimycin A-induced mitochondrial dysfunction by Nelumbo nucifera seed extracts. Environmental Toxicology and Pharmacology 36:1, pages 19-29.
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Jie Yang, Fang Lv, Xiao-qing Chen, Wei-xi Cui, Li-hong Chen, Xiao-dong Wen & Qiang Wang. (2013) Pharmacokinetic study of major bioactive components in rats after oral administration of extract of Ilex hainanensis by high-performance liquid chromatography/electrospray ionization mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 77, pages 21-28.
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