Advanced search
Publication Cover
Bioscience, Biotechnology, and Biochemistry Volume 76, 2012 - Issue 3
Journal homepage
391
Views
24
CrossRef citations to date
0
Altmetric
Original Articles

Sudachitin, a Polymethoxyflavone from Citrus sudachi, Suppresses Lipopolysaccharide-Induced Inflammatory Responses in Mouse Macrophage-Like RAW264 Cells

Keizo YUASADepartment of Biological Science and Technology, The University of Tokushima Graduate School
,
Kaori TADADepartment of Biological Science and Technology, The University of Tokushima Graduate School
,
Genki HARITADepartment of Biological Science and Technology, The University of Tokushima Graduate School
,
Tomomi FUJIMOTODepartment of Biological Science and Technology, The University of Tokushima Graduate School
,
Masao TSUKAYAMADepartment of Biological Science and Technology, The University of Tokushima Graduate School
&
Akihiko TSUJIDepartment of Biological Science and Technology, The University of Tokushima Graduate School
Pages 598-600 | Received 21 Oct 2011, Accepted 05 Dec 2011, Published online: 22 May 2014

Citations (24)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Shogo Abe, Saki Hirose, Mami Nishitani, Ichiro Yoshida, Masao Tsukayama, Akihiko Tsuji & Keizo Yuasa. (2018) Citrus peel polymethoxyflavones, sudachitin and nobiletin, induce distinct cellular responses in human keratinocyte HaCaT cells. Bioscience, Biotechnology, and Biochemistry 82:12, pages 2064-2071.
Read now

Articles from other publishers (23)

Kazuo Noguchi, Chinami Ueda, Mako Watanabe, Misaki Goma, Saki Umeda, Sawako Tabira, Koto Furuyama & Haruna Kanae. (2023) Endothelium-Independent Vasorelaxant Effects of Sudachitin and Demethoxysudachitin, Polymethoxyflavone from the Peel of <i>Citrus sudachi</i> on Isolated Rat Aorta. Biological and Pharmaceutical Bulletin 46:11, pages 1583-1591.
Crossref
Mahdi Vajdi & Mahdieh Abbasalizad Farhangi. (2023) Citrus peel derived poly-methoxylated flavones (PMF). International Journal for Vitamin and Nutrition Research 93:3, pages 252-267.
Crossref
Mitko Mladenov, Lubomir Lubomirov, Olaf Grisk, Dimiter Avtanski, Vadim Mitrokhin, Iliyana Sazdova, Milena Keremidarska-Markova, Yana Danailova, Georgi Nikolaev, Rossitza Konakchieva & Hristo Gagov. (2023) Oxidative Stress, Reductive Stress and Antioxidants in Vascular Pathogenesis and Aging. Antioxidants 12:5, pages 1126.
Crossref
Tomoki Abe, Tomoyuki Sato & Kazutoshi Murotomi. (2023) Sudachitin and Nobiletin Stimulate Lipolysis via Activation of the cAMP/PKA/HSL Pathway in 3T3-L1 Adipocytes. Foods 12:10, pages 1947.
Crossref
Gianfranco Fontana, Maurizio Bruno, Francesco Sottile & Natale Badalamenti. (2022) The Chemistry and the Anti-Inflammatory Activity of Polymethoxyflavonoids from Citrus Genus. Antioxidants 12:1, pages 23.
Crossref
Allah Rakha, Nehal Umar, Roshina Rabail, Masood Sadiq Butt, Marek Kieliszek, Abdo Hassoun & Rana Muhammad Aadil. (2022) Anti-inflammatory and anti-allergic potential of dietary flavonoids: A review. Biomedicine & Pharmacotherapy 156, pages 113945.
Crossref
Shuhai Chen, Masaaki Nishi, Yuji Morine, Kozo Yoshikawa, Takuya Tokunaga, Hideya Kashihara, Chie Takasu, Yuma Wada, Toshiaki Yoshimoto, Akiko Nakamoto, Tohru Sakai & Mitsuo Shimada. (2022) Polymethoxylated flavone sudachitin is a safe anticancer adjuvant that targets glycolysis in cancer‑associated fibroblasts. Oncology Letters 24:1.
Crossref
Yasuhiro Shikishima, Rie Tsutsumi, Ayuka Kawakami, Hiroyuki Miura, Yoshitaka Nii & Hiroshi Sakaue. (2021) Sudachi peel extract powder including the polymethoxylated flavone sudachitin improves visceral fat content in individuals at risk for developing diabetes. Food Science & Nutrition 9:8, pages 4076-4084.
Crossref
Youngshim Choi & Liqing Yu. (2021) Natural Bioactive Compounds as Potential Browning Agents in White Adipose Tissue. Pharmaceutical Research 38:4, pages 549-567.
Crossref
Shogo Abe & Keizo Yuasa. (2019) Sudachitin, a polymethoxyflavone from Citrus sudachi, induces apoptosis via the regulation of MAPK pathways in human keratinocyte HaCaT cells. Biochemical and Biophysical Research Communications 519:2, pages 344-350.
Crossref
Kuan-Hung Lu, Huey-Yin Lee, Yung-Lin Chu, Chi-Tang Ho & Lee-Yan Sheen. (2019) Bitter orange peel extract induces endoplasmic reticulum-mediated autophagy in human hepatoma cells. Journal of Functional Foods 60, pages 103404.
Crossref
Yoshitaka Hosokawa, Ikuko Hosokawa, Kazumi Ozaki & Takashi Matsuo. (2019) Sudachitin Inhibits Matrix Metalloproteinase-1 and -3 Production in Tumor Necrosis Factor-α-Stimulated Human Periodontal Ligament Cells. Inflammation 42:4, pages 1456-1462.
Crossref
Yoshitaka Nii, Yasuhiro ShikishimaTohru Sakai. (2019) Improvement of Lipid Metabolism in Mice Fed a High-Fat Diet Treated with Sudachitin and Development of Sudachi Peel Extract Powderスダチ果皮ポリフェノール（スダチチン）の機能性と食品素材開発. Nippon Shokuhin Kagaku Kogaku Kaishi 66:7, pages 233-237.
Crossref
Mami Mitani, Yuki Minatogawa, Akiko Nakamoto, Mariko Nakamoto, Emi Shuto, Yoshitaka Nii & Tohru Sakai. (2019) Sudachitin, polymethoxyflavone from <i>Citrus sudachi</i>, enhances antigen-specific cellular and humoral immune responses in BALB/c mice. Journal of Clinical Biochemistry and Nutrition 64:2, pages 158-163.
Crossref
Jin Tatsuzaki, Tomohiko Ohwada, Yuko Otani, Reiko Inagi & Tsutomu Ishikawa. (2018) A simple and effective preparation of quercetin pentamethyl ether from quercetin. Beilstein Journal of Organic Chemistry 14, pages 3112-3121.
Crossref
Yoko Ohyama, Junta Ito, Victor J. Kitano, Jun Shimada & Yoshiyuki Hakeda. (2018) The polymethoxy flavonoid sudachitin suppresses inflammatory bone destruction by directly inhibiting osteoclastogenesis due to reduced ROS production and MAPK activation in osteoclast precursors. PLOS ONE 13:1, pages e0191192.
Crossref
Zhao Gao, Wen Gao, Su-Ling Zeng, Ping Li & E-Hu Liu. (2018) Chemical structures, bioactivities and molecular mechanisms of citrus polymethoxyflavones. Journal of Functional Foods 40, pages 498-509.
Crossref
Satoru Horigome, Misato Maeda, Hsin-Jung Ho, Hitoshi Shirakawa & Michio Komai. (2016) Effect of Kaempferia parviflora extract and its polymethoxyflavonoid components on testosterone production in mouse testis-derived tumour cells. Journal of Functional Foods 26, pages 529-538.
Crossref
Xinmiao Lv, Siyu Zhao, Zhangchi Ning, Honglian Zeng, Yisong Shu, Ou Tao, Cheng Xiao, Cheng Lu & Yuanyan Liu. (2015) Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health. Chemistry Central Journal 9:1.
Crossref
Ji Eun Lee, Ji Hye Kim & Min Young Kim. (2015) Changes in Phenolic Composition, Antioxidant and Antidiabetic Properties of Jeju Citrus sudachi as Influenced by Maturity. Journal of Life Science 25:11, pages 1311-1318.
Crossref
Satoshi Okuyama, Kazuhiro Miyoshi, Yuichi Tsumura, Yoshiaki Amakura, Morio Yoshimura, Takashi Yoshida, Mitsunari Nakajima & Yoshiko Furukawa. (2015) 3,5,6,7,8,3′,4′-Heptamethoxyflavone, a Citrus Polymethoxylated Flavone, Attenuates Inflammation in the Mouse Hippocampus. Brain Sciences 5:2, pages 118-129.
Crossref
Qun Lu, Li Yang, Hai-Yan Zhao, Jian-Guo Jiang & Xi-Lin Xu. (2013) Protective effect of compounds from the flowers of Citrus aurantium L. var. amara Engl against carbon tetrachloride-induced hepatocyte injury. Food and Chemical Toxicology 62, pages 432-435.
Crossref
Keizo Yuasa, Go Futamatsu, Tsuyoshi Kawano, Masaki Muroshita, Yoko Kageyama, Hiromi Taichi, Hiroshi Ishikawa, Masami Nagahama, Yoshiko Matsuda & Akihiko Tsuji. (2012) Subtilisin-like proprotein convertase paired basic amino acid-cleaving enzyme?4 is required for chondrogenic differentiation in ATDC5 cells. FEBS Journal 279:21, pages 3997-4009.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.