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Bioscience, Biotechnology, and Biochemistry Volume 64, 2000 - Issue 4
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Original Articles

Enzymatic Production of trans-4-Hydroxy-L-proline by Regio- and Stereospecific Hydroxylation of L-Proline

Takeshi SHIBASAKITokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.
,
Hideo MORITokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.
&
Akio OZAKITokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd.
Pages 746-750 | Received 15 Oct 1999, Accepted 24 Nov 1999, Published online: 22 May 2014

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Ryotaro Hara, Naoko Uchiumi, Naoko Okamoto & Kuniki Kino. (2014) Regio- and stereoselective oxygenation of proline derivatives by using microbial 2-oxoglutarate-dependent dioxygenases. Bioscience, Biotechnology, and Biochemistry 78:8, pages 1384-1388.
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Yu Gong, Ruiqi Wang, Ling Ma, Shuo Wang, Changgeng Li & Qingyang Xu. (2023) Optimization of trans-4-hydroxyproline synthesis pathway by rearrangement center carbon metabolism in Escherichia coli. Microbial Cell Factories 22:1.
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Xiaoyan Hu, Xue Huang, Jiao Liu, Ping Zheng, Weimin Gong & Lin Yang. (2023) Structures of L -proline trans -hydroxylase reveal the catalytic specificity and provide deeper insight into AKG-dependent hydroxylation . Acta Crystallographica Section D Structural Biology 79:4, pages 318-325.
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Zhenyu Zhang, Weike Su, Yunyun Bao, Qianqian Huang, Kai Ye, Pengfu Liu & Xiaohe Chu. (2022) Modular reconstruction and optimization of the trans-4-hydroxy-L-proline synthesis pathway in Escherichia coli. Microbial Cell Factories 21:1.
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Ryotaro Hara, Yuta Nakajima, Hiroaki Yanagawa, Ryo Gawasawa, Izumi Hirasawa & Kuniki Kino. (2021) Enzymatic Synthesis of l - threo -β-Hydroxy-α-Amino Acids via Asymmetric Hydroxylation Using 2-Oxoglutarate-Dependent Hydroxylase from Sulfobacillus thermotolerans Strain Y0017 . Applied and Environmental Microbiology 87:20.
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Fabian Brandenburg, Eleni Theodosiou, Carolin Bertelmann, Marcel Grund, Stephan Klähn, Andreas Schmid & Jens O. Krömer. (2021) Trans-4-hydroxy-L-proline production by the cyanobacterium Synechocystis sp. PCC 6803. Metabolic Engineering Communications 12, pages e00155.
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Xiulai Chen, Juyang Yi, Jia Liu, Qiuling Luo & Liming Liu. (2020) Enzymatic production of trans ‐4‐hydroxy‐ l ‐proline by proline 4‐hydroxylase . Microbial Biotechnology 14:2, pages 479-487.
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Xiulai Chen, Juyang Yi, Wei Song, Jia Liu, Qiuling Luo & Liming Liu. (2020) Chassis engineering of Escherichia coli for trans ‐4‐hydroxy‐ l ‐proline production . Microbial Biotechnology 14:2, pages 392-402.
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Liangzhen Jiang, Jing Pang, Lixia Yang, Wei Li, Lili Duan, Guolin Zhang & Yinggang Luo. (2021) Engineering endogenous l-proline biosynthetic pathway to boost trans-4-hydroxy-l-proline production in Escherichia coli. Journal of Biotechnology 329, pages 104-117.
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Jingxuan Qiu, Haishuang Huang, Hui He, Haoyou Liu, Shen Hu, Jiaming Han, Ying Guo & Peng Wang. (2020) Measurement and Correlation of trans -4-Hydroxy- l -proline Solubility in Sixteen Individual Solvents and a Water + Acetonitrile Binary Solvent System . Journal of Chemical & Engineering Data 66:1, pages 575-587.
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Shuke Wu, Radka Snajdrova, Jeffrey C. Moore, Kai Baldenius & Uwe T. Bornscheuer. (2020) Biocatalysis: Enzymatic Synthesis for Industrial Applications. Angewandte Chemie International Edition 60:1, pages 88-119.
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Sergio Martínez-Rodríguez, Jesus M. Torres, Pilar Sánchez & Esperanza Ortega. (2020) Overview on Multienzymatic Cascades for the Production of Non-canonical α-Amino Acids. Frontiers in Bioengineering and Biotechnology 8.
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Mengfei Long, Meijuan XuZhenfeng MaXuewei PanJiajia YouMengkai HuYu ShaoTaowei YangXian ZhangZhiming Rao. (2020) Significantly enhancing production of trans -4-hydroxy- l -proline by integrated system engineering in Escherichia coli . Science Advances 6:21.
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Tristan J. Smart, Refaat B. Hamed, Timothy D.W. Claridge & Christopher J. Schofield. (2020) Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles. Bioorganic Chemistry 94, pages 103386.
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Jing Zhao, Chao Liu, Xuan Guo, Jinyu Wang, Haiping Liu, Ping Zheng, Jibin Sun & Yanhe Ma. (2019) Efficient production of trans-3-hydroxyproline by a bacterial trans-3-proline hydroxylase and characterization of enzymatic properties. Biochemical Engineering Journal 147, pages 57-61.
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Chao Liu, Jing Zhao, Jiao Liu, Xuan Guo, Deming Rao, Haiping Liu, Ping Zheng, Jibin Sun & Yanhe Ma. (2018) Simultaneously improving the activity and thermostability of a new proline 4-hydroxylase by loop grafting and site-directed mutagenesis. Applied Microbiology and Biotechnology 103:1, pages 265-277.
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