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Muharrem Balci, Lesley L. Rhodes, Tomohiro Nishimura, J. Sam Murray, D. Tim Harwood, A. Lincoln MacKenzie, Tony Bui, Catherine Moisan, Lucy Thompson & Kirsty F. Smith. (2023) Molecular detection and distribution of the genera Amphidoma and Azadinium (Amphidomataceae, Dinophyceae) in the coastal waters of Aotearoa/New Zealand. New Zealand Journal of Marine and Freshwater Research 57:1, pages 47-62.
Read now
Read now
K. J. James
, M. J. Fidalgo Sáez, A. Furey & M. Lehane. (2004) Azaspiracid poisoning, the food-borne illness associated with shellfish consumption. Food Additives & Contaminants 21:9, pages 879-892.
Read now
Read now
K. J. James, M. Lehane, C. Moroney, P. Fernandez-Puente, M. Satake, T. Yasumoto & A. Furey. (2002) Azaspiracid shellfish poisoning: unusual toxin dynamics in shellfish and the increased risk of acute human intoxications. Food Additives & Contaminants 19:6, pages 555-561.
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Articles from other publishers (129)
Ingunn A. Samdal, Morten Sandvik, Jennie Vu, Merii S. Sukenthirarasa, Sinthuja Kanesamurthy, Kjersti L.E. Løvberg, Jane Kilcoyne, Craig J. Forsyth, Elliott J. Wright & Christopher O. Miles. (2022) Preparation and characterization of an immunoaffinity column for the selective extraction of azaspiracids. Journal of Chromatography B 1207, pages 123360.
Crossref
Crossref
Andrew D. Turner, Adam M. Lewis, Kirsty Bradley & Benjamin H. Maskrey. (2021) Marine invertebrate interactions with Harmful Algal Blooms – Implications for One Health. Journal of Invertebrate Pathology 186, pages 107555.
Crossref
Crossref
Mayu Ozawa, Hajime Uchida, Ryuichi Watanabe, Ryoji Matsushima, Hiroshi Oikawa, Kazuya Takahashi, Mitsunori Iwataki & Toshiyuki Suzuki. (2021) Complex profiles of azaspiracid analogues in two culture strains of Azadinium poporum (Amphidomataceae, Dinophyceae) isolated from Japanese coastal waters determined by LC-MS/MS. Toxicon 199, pages 145-155.
Crossref
Crossref
Michael Dillon, Maja A. Zaczek-Moczydlowska, Christine Edwards, Andrew D. Turner, Peter I. Miller, Heather Moore, April McKinney, Linda Lawton & Katrina Campbell. (2021) Current Trends and Challenges for Rapid SMART Diagnostics at Point-of-Site Testing for Marine Toxins. Sensors 21:7, pages 2499.
Crossref
Crossref
Kichul Cho, Jina Heo, Jinwook Han, Hyun Dae Hong, Hancheol Jeon, Hyun-Ju Hwang, Chang-Yu Hong, Daekyung Kim, Jong Won Han & Kyunghwa Baek. (2020) Industrial Applications of Dinoflagellate Phycotoxins Based on Their Modes of Action: A Review. Toxins 12:12, pages 805.
Crossref
Crossref
Ingunn A. Samdal, Kjersti E. Løvberg, Anja B. Kristoffersen, Lyn R. Briggs, Jane Kilcoyne, Craig J. Forsyth & Christopher O. Miles. (2019) A Practical ELISA for Azaspiracids in Shellfish via Development of a New Plate-Coating Antigen. Journal of Agricultural and Food Chemistry 67:8, pages 2369-2376.
Crossref
Crossref
Bernd Krock, Urban Tillmann, Jan Tebben, Nicole Trefault & Haifeng Gu. (2019) Two novel azaspiracids from Azadinium poporum, and a comprehensive compilation of azaspiracids produced by Amphidomataceae, (Dinophyceae). Harmful Algae 82, pages 1-8.
Crossref
Crossref
Isidro Tamele, Marisa Silva & Vitor Vasconcelos. (2019) The Incidence of Marine Toxins and the Associated Seafood Poisoning Episodes in the African Countries of the Indian Ocean and the Red Sea. Toxins 11:1, pages 58.
Crossref
Crossref
Jane Kilcoyne, Pearse McCarron, Michael J. Twiner, Frode Rise, Philipp Hess, Alistair L. Wilkins & Christopher O. Miles. (2018)
Identification of 21,22-Dehydroazaspiracids in Mussels (
Mytilus edulis
) and in Vitro Toxicity of Azaspiracid-26
. Journal of Natural Products 81:4, pages 885-893.
Crossref
Crossref
Christopher O. Miles, Jane Kilcoyne, Pearse McCarron, Sabrina D. Giddings, Thor Waaler, Thomas Rundberget, Ingunn A. Samdal & Kjersti E. Løvberg. (2018)
Selective Extraction and Purification of Azaspiracids from Blue Mussels (
Mytilus edulis
) Using Boric Acid Gel
. Journal of Agricultural and Food Chemistry 66:11, pages 2962-2969.
Crossref
Crossref
Samanta S. Khora & Soumya Jal. 2018. Microbial Contamination and Food Degradation. Microbial Contamination and Food Degradation
177
233
.
Amandine M.N. Caruana & Zouher Amzil. 2018. Microalgae in Health and Disease Prevention. Microalgae in Health and Disease Prevention
263
305
.
S.J. Pyle & P.J. Meberg. 2018. Comprehensive Toxicology. Comprehensive Toxicology
101
119
.
Rachele Rossi, Carmela Dell’Aversano, Bernd Krock, Patrizia Ciminiello, Isabella Percopo, Urban Tillmann, Vittorio Soprano & Adriana Zingone. (2016) Mediterranean Azadinium dexteroporum (Dinophyceae) produces six novel azaspiracids and azaspiracid-35: a structural study by a multi-platform mass spectrometry approach. Analytical and Bioanalytical Chemistry 409:4, pages 1121-1134.
Crossref
Crossref
Toshiyuki Suzuki, Hajime Uchida & Ryuichi Watanabe. 2017. Recent Advances in the Analysis of Marine Toxins. Recent Advances in the Analysis of Marine Toxins
137
192
.
Sara F. Ferreiro, Natalia Vilariño, Cristina Carrera, M. Carmen Louzao, Antonio G. Cantalapiedra, Germán Santamarina, J. Manuel Cifuentes, Andrés C. Vieira & Luis M. Botana. (2016) Subacute Cardiovascular Toxicity of the Marine Phycotoxin Azaspiracid-1 in Rats. Toxicological Sciences 151:1, pages 104-114.
Crossref
Crossref
Philipp Hess, Michael J. Twiner, Jane Kilcoyne & Silvio Sosa. 2016. Marine and Freshwater Toxins. Marine and Freshwater Toxins
169
191
.
Jane Kilcoyne, Pearse McCarron, Philipp Hess & Christopher O. Miles. (2015)
Effects of Heating on Proportions of Azaspiracids 1–10 in Mussels (
Mytilus edulis
) and Identification of Carboxylated Precursors for Azaspiracids 5, 10, 13, and 15
. Journal of Agricultural and Food Chemistry 63:51, pages 10980-10987.
Crossref
Crossref
Bernd Krock, Urban Tillmann, Éric Potvin, Hae Jeong, Wolfgang Drebing, Jane Kilcoyne, Ahmed Al-Jorani, Michael Twiner, Qun Göthel & Matthias Köck. (2015) Structure Elucidation and in Vitro Toxicity of New Azaspiracids Isolated from the Marine Dinoflagellate Azadinium poporum. Marine Drugs 13:11, pages 6687-6702.
Crossref
Crossref
Ingunn A. Samdal, Kjersti E. Løvberg, Lyn R. Briggs, Jane Kilcoyne, Jianyan Xu, Craig J. Forsyth & Christopher O. Miles. (2015) Development of an ELISA for the Detection of Azaspiracids. Journal of Agricultural and Food Chemistry 63:35, pages 7855-7861.
Crossref
Crossref
Jane Kilcoyne, Michael J. Twiner, Pearse McCarron, Sheila Crain, Sabrina D. Giddings, Barry Foley, Frode Rise, Philipp Hess, Alistair L. Wilkins & Christopher O. Miles. (2015)
Structure Elucidation, Relative LC–MS Response and In Vitro Toxicity of Azaspiracids
7
–
10
Isolated from Mussels (
Mytilus edulis
)
. Journal of Agricultural and Food Chemistry 63:20, pages 5083-5091.
Crossref
Crossref
Pearse McCarron, Sabrina D. Giddings, Kelley L. Reeves, Philipp Hess & Michael A. Quilliam. (2014) A mussel (Mytilus edulis) tissue certified reference material for the marine biotoxins azaspiracids. Analytical and Bioanalytical Chemistry 407:11, pages 2985-2996.
Crossref
Crossref
Manuel Cifuentes, Andrés Crespo & Roberto Bermúdez. 2015. Phycotoxins. Phycotoxins
463
512
.
Philipp Hess, Michael J. Twiner, Jane Kilcoyne & Silvio Sosa. 2014. Marine and Freshwater Toxins. Marine and Freshwater Toxins
1
19
.
Daniel O'Driscoll, Zuzana Škrabáková & Kevin J. James. (2014) Confirmation of extensive natural distribution of azaspiracids in the tissue compartments of mussels (Mytilus edulis). Toxicon 92, pages 123-128.
Crossref
Crossref
Jane Kilcoyne, Ciara Nulty, Thierry Jauffrais, Pearse McCarron, Fabienne Herve, Barry Foley, Frode Rise, Sheila Crain, Alistair L. Wilkins, Michael J. Twiner, Philipp Hess & Christopher O. Miles. (2014)
Isolation, Structure Elucidation, Relative LC-MS Response, and in Vitro Toxicity of Azaspiracids from the Dinoflagellate
Azadinium spinosum
. Journal of Natural Products 77:11, pages 2465-2474.
Crossref
Crossref
Jean‐Michel KornprobstJean‐Michel Kornprobst. 2014. Encyclopedia of Marine Natural Products. Encyclopedia of Marine Natural Products
1419
1460
.
Jean‐Michel KornprobstJean‐Michel Kornprobst. 2014. Encyclopedia of Marine Natural Products. Encyclopedia of Marine Natural Products
1333
1419
.
Jane Kilcoyne, Pearse McCarron, Michael J. Twiner, Ciara Nulty, Sheila Crain, Michael A. Quilliam, Frode Rise, Alistair L. Wilkins & Christopher O. Miles. (2014)
Epimers of Azaspiracids: Isolation, Structural Elucidation, Relative LC-MS Response, and
in Vitro
Toxicity of 37-
epi
-Azaspiracid-1
. Chemical Research in Toxicology 27:4, pages 587-600.
Crossref
Crossref
Luis BotanaJuan Otero. 2014. Seafood and Freshwater Toxins. Seafood and Freshwater Toxins
123
196
.
Luis BotanaMichael Twiner, Philipp Hess & Gregory Doucette. 2014. Seafood and Freshwater Toxins. Seafood and Freshwater Toxins
823
856
.
Luis BotanaPhilipp Hess, Pearse McCarron, Bernd Krock, Jane Kilcoyne & Christopher Miles. 2014. Seafood and Freshwater Toxins. Seafood and Freshwater Toxins
799
822
.
Luis BotanaRex Munday. 2014. Seafood and Freshwater Toxins. Seafood and Freshwater Toxins
197
290
.
T. Jauffrais, V. Séchet, P. Truquet, Zouher Amzil, C. Herrenknecht & P. Hess. 2014. Molluscan Shellfish Safety. Molluscan Shellfish Safety
197
204
.
Thierry Jauffrais, Andrea Contreras, Christine Herrenknecht, Philippe Truquet, Véronique Séchet, Urban Tillmann & Philipp Hess. (2012) Effect of Azadinium spinosum on the feeding behaviour and azaspiracid accumulation of Mytilus edulis. Aquatic Toxicology 124-125, pages 179-187.
Crossref
Crossref
Bernd Krock, Urban Tillmann, Daniela Voß, Boris P. Koch, Rafael Salas, Matthias Witt, Éric Potvin & Hae Jin Jeong. (2012) New azaspiracids in Amphidomataceae (Dinophyceae). Toxicon 60:5, pages 830-839.
Crossref
Crossref
Thierry Jauffrais, Claire Marcaillou, Christine Herrenknecht, Philippe Truquet, Véronique Séchet, Elodie Nicolau, Urban Tillmann & Philipp Hess. (2012) Azaspiracid accumulation, detoxification and biotransformation in blue mussels (Mytilus edulis) experimentally fed Azadinium spinosum. Toxicon 60:4, pages 582-595.
Crossref
Crossref
Su-Un Kim, Dong-Hyun Yuk, Young-Ae Park, Jin-Ah Kim, Ae-Sook Park & Yun-Chun Kim. (2012) Analysis of Diarrhetic Shellfish Poisoning Toxins by Liquid Chromatography-electrospray Ionization Mass Spectrometry. Korean Journal of Food Science and Technology 44:4, pages 390-392.
Crossref
Crossref
Thierry Jauffrais, Jane Kilcoyne, Véronique Séchet, Christine Herrenknecht, Philippe Truquet, Fabienne Hervé, Jean Baptiste Bérard, Cíara Nulty, Sarah Taylor, Urban Tillmann, Christopher O. Miles & Philipp Hess. (2012) Production and Isolation of Azaspiracid-1 and -2 from Azadinium spinosum Culture in Pilot Scale Photobioreactors. Marine Drugs 10:12, pages 1360-1382.
Crossref
Crossref
Thierry Jauffrais, Christine Herrenknecht, Véronique Séchet, Manoella Sibat, Urban Tillmann, Bernd Krock, Jane Kilcoyne, Christopher O. Miles, Pearse McCarron, Zouher Amzil & Philipp Hess. (2012) Quantitative analysis of azaspiracids in Azadinium spinosum cultures. Analytical and Bioanalytical Chemistry 403:3, pages 833-846.
Crossref
Crossref
Michael J. Twiner, Racha El-Ladki, Jane Kilcoyne & Gregory J. Doucette. (2012) Comparative Effects of the Marine Algal Toxins Azaspiracid-1, -2, and -3 on Jurkat T Lymphocyte Cells. Chemical Research in Toxicology 25:3, pages 747-754.
Crossref
Crossref
Rafael Salas, Urban Tillmann, Uwe John, Jane Kilcoyne, Amanda Burson, Caoimhe Cantwell, Philipp Hess, Thierry Jauffrais & Joe Silke. (2011) The role of Azadinium spinosum (Dinophyceae) in the production of azaspiracid shellfish poisoning in mussels. Harmful Algae 10:6, pages 774-783.
Crossref
Crossref
Edmond Gravel. 2011. Biomimetic Organic Synthesis. Biomimetic Organic Synthesis
271
315
.
Daniel O’Driscoll, Zuzana Škrabáková, John O’Halloran, Frank N. A. M. van Pelt & Kevin J. James. (2011) Mussels Increase Xenobiotic (Azaspiracid) Toxicity Using a Unique Bioconversion Mechanism. Environmental Science & Technology 45:7, pages 3102-3108.
Crossref
Crossref
Zuzana Škrabáková, John O'Halloran, Frank N.A.M. van Pelt & Kevin J. James. (2010) Food contaminant analysis at ultra-high mass resolution: application of hybrid linear ion trap - orbitrap mass spectrometry for the determination of the polyether toxins, azaspiracids, in shellfish. Rapid Communications in Mass Spectrometry 24:20, pages 2966-2974.
Crossref
Crossref
Isa Ruppen Canás, Keith O’Callaghan, Cian Moroney, Brett Hamilton, Kevin J. James & Ambrose Furey. (2010) The development of a rapid method for the isolation of four azaspiracids for use as reference materials for quantitative LC–MS–MS methods. Analytical and Bioanalytical Chemistry 398:3, pages 1477-1491.
Crossref
Crossref
Ambrose Furey, Sinead O'Doherty, Keith O'Callaghan, Mary Lehane & Kevin J. James. (2010) Azaspiracid poisoning (AZP) toxins in shellfish: Toxicological and health considerations. Toxicon 56:2, pages 173-190.
Crossref
Crossref
K. J. JAMES, B. CAREY, J. O'HALLORAN, F. N. A. M. van PELT & Z. ŠKRABÁKOVÁ. (2010) Shellfish toxicity: human health implications of marine algal toxins. Epidemiology and Infection 138:7, pages 927-940.
Crossref
Crossref
Zhengyu Cao, Keith T. LePage, Michael O. Frederick, Kyriacos C. Nicolaou & Thomas F. Murray. (2010) Involvement of Caspase Activation in Azaspiracid-Induced Neurotoxicity in Neocortical Neurons. Toxicological Sciences 114:2, pages 323-334.
Crossref
Crossref
A. López-Rivera, K. O’Callaghan, M. Moriarty, D. O’Driscoll, B. Hamilton, M. Lehane, K.J. James & A. Furey. (2010) First evidence of azaspiracids (AZAs): A family of lipophilic polyether marine toxins in scallops (Argopecten purpuratus) and mussels (Mytilus chilensis) collected in two regions of Chile. Toxicon 55:4, pages 692-701.
Crossref
Crossref
Francesco Silvestre & Elisabetta Tosti. (2010) Impact of Marine Drugs on Cytoskeleton-Mediated Reproductive Events. Marine Drugs 8:4, pages 881-915.
Crossref
Crossref
Carmen Vale, Kyriacos C. Nicolaou, Michael O. Frederick, Mercedes R. Vieytes & Luis M. Botana. (2010) Cell Volume Decrease as a Link between Azaspiracid-Induced Cytotoxicity and c-Jun-N-Terminal Kinase Activation in Cultured Neurons. Toxicological Sciences 113:1, pages 158-168.
Crossref
Crossref
Gian Paolo Rossini & Philipp Hess. 2010. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology
65
122
.
Natalia Vilariño, Eva Fonfría, M. Carmen Louzao & Luis Botana. (2009) Use of Biosensors as Alternatives to Current Regulatory Methods for Marine Biotoxins. Sensors 9:11, pages 9414-9443.
Crossref
Crossref
Sherwood Hall. 2009. Pathogens and Toxins in Foods. Pathogens and Toxins in Foods
233
247
.
Michael O. Frederick , Sandra De Lamo Marin, Kim D. Janda, K. C. Nicolaou & Tobin J. Dickerson. (2009) Monoclonal Antibodies with Orthogonal Azaspiracid Epitopes. ChemBioChem 10:10, pages 1625-1629.
Crossref
Crossref
Philipp Hess, Tim Butter, Andrew Petersen, Joe Silke & Terry McMahon. (2009) Performance of the EU-harmonised mouse bioassay for lipophilic toxins for the detection of azaspiracids in naturally contaminated mussel (Mytilus edulis) hepatopancreas tissue homogenates characterised by liquid chromatography coupled to tandem mass spectrometry. Toxicon 53:7-8, pages 713-722.
Crossref
Crossref
Reiko Ueoka, Akihiro Ito, Miho Izumikawa, Satoko Maeda, Motoki Takagi, Kazuo Shin-ya, Minoru Yoshida, Rob. W.M. van Soest & Shigeki Matsunaga. (2009) Isolation of azaspiracid-2 from a marine sponge Echinoclathria sp. as a potent cytotoxin. Toxicon 53:6, pages 680-684.
Crossref
Crossref
Ralf Kellmann, Carlos A.M. Schaffner, Toril A. Gr?nset, Masayuki Satake, Mathias Ziegler & Kari E. Fladmark. (2009) Proteomic response of human neuroblastoma cells to azaspiracid-1. Journal of Proteomics 72:4, pages 695-707.
Crossref
Crossref
Thomas Rundberget, Eli Gustad, Ingunn A. Samdal, Morten Sandvik & Christopher O. Miles. (2009) A convenient and cost-effective method for monitoring marine algal toxins with passive samplers. Toxicon 53:5, pages 543-550.
Crossref
Crossref
Elie Fux, Ronel Bire & Philipp Hess. (2009) Comparative accumulation and composition of lipophilic marine biotoxins in passive samplers and in mussels (M. edulis) on the West Coast of Ireland. Harmful Algae 8:3, pages 523-537.
Crossref
Crossref
Pearse McCarron, Jane Kilcoyne, Christopher O. Miles & Philipp Hess. (2008) Formation of Azaspiracids-3, -4, -6, and -9 via Decarboxylation of Carboxyazaspiracid Metabolites from Shellfish. Journal of Agricultural and Food Chemistry 57:1, pages 160-169.
Crossref
Crossref
Masato Oikawa, Makoto Sasaki & Taizo Iwayama. (2009) Synthesis of Open-Chain C21-C40 Fragment of Azaspiracid-1. HETEROCYCLES 78:3, pages 609.
Crossref
Crossref
H. Hégaret, G.H. Wikfors & S.E. Shumway. 2009. Shellfish Safety and Quality. Shellfish Safety and Quality
43
80
.
Bernd Krock, Urban Tillmann, Uwe John & Allan D. Cembella. (2009) Characterization of azaspiracids in plankton size-fractions and isolation of an azaspiracid-producing dinoflagellate from the North Sea. Harmful Algae 8:2, pages 254-263.
Crossref
Crossref
Carmen Alfonso, Nils Rehmann, Philipp Hess, Amparo Alfonso, Carolina B. Wandscheer, María Abuín, Carmen Vale, Paz Otero, Mercedes R. Vieytes & Luis M. Botana. (2008) Evaluation of Various pH and Temperature Conditions on the Stability of Azaspiracids and Their Importance in Preparative Isolation and Toxicological Studies. Analytical Chemistry 80:24, pages 9672-9680.
Crossref
Crossref
David A. Evans, Lisbet Kværnø, Travis B. Dunn, André Beauchemin, Brian Raymer, Jason A. Mulder, Edward J. Olhava, Martin Juhl, Katsuji Kagechika & David A. Favor. (2008) Total Synthesis of (+)-Azaspiracid-1. An Exhibition of the Intricacies of Complex Molecule Synthesis. Journal of the American Chemical Society 130:48, pages 16295-16309.
Crossref
Crossref
Natalia Vilariño. (2008) Marine toxins and the cytoskeleton: azaspiracids. The FEBS Journal 275:24, pages 6075-6081.
Crossref
Crossref
Donald G. Barceloux. 2008. Medical Toxicology of Natural Substances. Medical Toxicology of Natural Substances
218
221
.
. (2008) Marine biotoxins in shellfish – Azaspiracid group ‐ Scientific Opinion of the Panel on Contaminants in the Food chain. EFSA Journal 6:10.
Crossref
Crossref
Carmen Vale, Carolina Wandscheer, K.C. Nicolaou, Michael O. Frederick, Carmen Alfonso, Mercedes R. Vieytes & Luis M. Botana. (2008) Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: Involvement of the c-Jun N-terminal kinase. Journal of Neuroscience Research 86:13, pages 2952-2962.
Crossref
Crossref
Natalia VilariñoK. C. NicolaouMichael O. FrederickEva CagideCarmen AlfonsoEva AlonsoMercedes R. VieytesLuis M. Botana. (2008) Azaspiracid Substituent at C1 Is Relevant to in Vitro Toxicity. Chemical Research in Toxicology 21:9, pages 1823-1831.
Crossref
Crossref
Zouher Amzil, Manoella Sibat, Florence Royer & Véronique Savar. (2008) First report on azaspiracid and yessotoxin groups detection in French shellfish. Toxicon 52:1, pages 39-48.
Crossref
Crossref
Paulo Vale, Ronel Bire & Philipp Hess. (2008) Confirmation by LC–MS/MS of azaspiracids in shellfish from the Portuguese north-western coast. Toxicon 51:8, pages 1449-1456.
Crossref
Crossref
K.J. Nzoughet, J.T.G. Hamilton, S.D. Floyd, A. Douglas, J. Nelson, L. Devine & C.T. Elliott. (2008) Azaspiracid: First evidence of protein binding in shellfish. Toxicon 51:7, pages 1255-1263.
Crossref
Crossref
Michael Twiner, Nils Rehmann, Philipp Hess & Gregory Doucette. (2008) Azaspiracid Shellfish Poisoning: A Review on the Chemistry, Ecology, and Toxicology with an Emphasis on Human Health Impacts. Marine Drugs 6:2, pages 39-72.
Crossref
Crossref
Carmen Alfonso, Amparo Alfonso, Paz Otero, Paula Rodríguez, Mercedes R. Vieytes, Chris Elliot, Cowan Higgins & Luis M. Botana. (2008) Purification of five azaspiracids from mussel samples contaminated with DSP toxins and azaspiracids. Journal of Chromatography B 865:1-2, pages 133-140.
Crossref
Crossref
Nils Rehmann, Philipp Hess & Michael A. Quilliam. (2008)
Discovery of new analogs of the marine biotoxin azaspiracid in blue mussels (
Mytilus edulis
) by ultra-performance liquid chromatography/tandem mass spectrometry
. Rapid Communications in Mass Spectrometry 22:4, pages 549-558.
Crossref
Crossref
Trine Torgersen, Nanna Bruun Bremnes, Thomas Rundberget & Tore Aune. (2008) Structural confirmation and occurrence of azaspiracids in Scandinavian brown crabs (Cancer pagurus). Toxicon 51:1, pages 93-101.
Crossref
Crossref
Kevin J. James, Daniel O’Driscoll, Javier García Fernández & Ambrose Furey. 2008. Food Contaminants and Residue Analysis. Food Contaminants and Residue Analysis
429
456
.
J.S. Yadav, Sipak Joyasawal, S.K. Dutta & A.C. Kunwar. (2007) Stereoselective synthesis of the ABCD ring framework of azaspiracids. Tetrahedron Letters 48:30, pages 5335-5340.
Crossref
Crossref
Natalia Vilariño, K.C. Nicolaou, Michael O. Frederick, Mercedes R. Vieytes & Luis M. Botana. (2007) Irreversible cytoskeletal disarrangement is independent of caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells. Biochemical Pharmacology 74:2, pages 327-335.
Crossref
Crossref
Natalia Vilariño. 2007. Phycotoxins: Chemistry and Biochemistry. Phycotoxins: Chemistry and Biochemistry
311
318
.
Michael O. Frederick, Kevin P. Cole, Goran Petrovic, Eriketi Loizidou & K. C. Nicolaou. 2007. Phycotoxins: Chemistry and Biochemistry. Phycotoxins: Chemistry and Biochemistry
397
409
.
Carmen Vale, Belén Gómez-Limia, K.C. Nicolaou, Michael O. Frederick, Mercedes R. Vieytes & Luis M. Botana. (2007) The c-Jun-N-Terminal Kinase is Involved in the Neurotoxic Effect of Azaspiracid-1. Cellular Physiology and Biochemistry 20:6, pages 957-966.
Crossref
Crossref
Patrick D. O'Connor & Margaret A. Brimble. (2007) Synthesis of macrocyclic shellfish toxins containing spiroimine moieties. Natural Product Reports 24:4, pages 869.
Crossref
Crossref
Carmen Vale, K. C. Nicolaou, Michael O. Frederick, Belén Gómez-Limia, Amparo Alfonso, Mercedes R. Vieytes & Luis M. Botana. (2006) Effects of Azaspiracid-1, A Potent Cytotoxic Agent, on Primary Neuronal Cultures. A Structure−Activity Relationship Study. Journal of Medicinal Chemistry 50:2, pages 356-363.
Crossref
Crossref
Aurelia Tubaro & James Hungerford. 2007. Veterinary Toxicology. Veterinary Toxicology
725
752
.
Hajime Toyofuku. (2006) Joint FAO/WHO/IOC activities to provide scientific advice on marine biotoxins (research report). Marine Pollution Bulletin 52:12, pages 1735-1745.
Crossref
Crossref
Emiko Ito, Michael O. Frederick, Theocharis V. Koftis, Wenjun Tang, Goran Petrovic, Taotao Ling & K.C. Nicolaou. (2006) Structure toxicity relationships of synthetic azaspiracid-1 and analogs in mice. Harmful Algae 5:5, pages 586-591.
Crossref
Crossref
Masato Oikawa, Tomoko Uehara, Taizo Iwayama & Makoto Sasaki. (2006) Synthetic Study of Azaspiracid-1: Synthesis of the EFGHI-Ring Fragment. Organic Letters 8:18, pages 3943-3946.
Crossref
Crossref
K. C. Nicolaou, Michael O. Frederick, Eriketi Z. Loizidou, Goran Petrovic, Kevin P. Cole, Theocharis V. Koftis & Yoichi M. A. Yamada. (2006) Second‐Generation Total Synthesis of Azaspiracids‐1, ‐2, and ‐3. Chemistry – An Asian Journal 1:1-2, pages 245-263.
Crossref
Crossref
Alistair L. Wilkins, Nils Rehmann, Trine Torgersen, Thomas Rundberget, Myra Keogh, Dirk Petersen, Philipp Hess, Frode Rise & Christopher O. Miles. (2006)
Identification of Fatty Acid Esters of Pectenotoxin-2 Seco Acid in Blue Mussels (
Mytilus edulis
) from Ireland
. Journal of Agricultural and Food Chemistry 54:15, pages 5672-5678.
Crossref
Crossref
Son Nguyen, Jianyan Xu & Craig J. Forsyth. (2006) Facile biomimetic syntheses of the azaspiracid spiroaminal. Tetrahedron 62:22, pages 5338-5346.
Crossref
Crossref
K. C. Nicolaou, Michael O. Frederick, Goran Petrovic, Kevin P. Cole & Eriketi Z. Loizidou. (2006) Total Synthesis and Confirmation of the Revised Structures of Azaspiracid‐2 and Azaspiracid‐3. Angewandte Chemie International Edition 45:16, pages 2609-2615.
Crossref
Crossref
K. C. Nicolaou, Michael O. Frederick, Goran Petrovic, Kevin P. Cole & Eriketi Z. Loizidou. (2006) Total Synthesis and Confirmation of the Revised Structures of Azaspiracid‐2 and Azaspiracid‐3. Angewandte Chemie 118:16, pages 2671-2677.
Crossref
Crossref
K. C. Nicolaou, Petri M. Pihko, Federico Bernal, Michael O. Frederick, Wenyuan Qian, Noriaki Uesaka, Nicole Diedrichs, Jürgen Hinrichs, Theocharis V. Koftis, Eriketi Loizidou, Goran Petrovic, Manuela Rodriquez, David Sarlah & Ning Zou. (2006) Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure. Journal of the American Chemical Society 128:7, pages 2244-2257.
Crossref
Crossref
P. Ciminiello & Ernesto Fattorusso. 2006. Molluscs. Molluscs
53
82
.
Masayuki Satake. 2006. Marine Natural Products. Marine Natural Products
21
51
.
Jatta E. Aho, Petri M. Pihko & Terhi K. Rissa. (2005) Nonanomeric Spiroketals in Natural Products: Structures, Sources, and Synthetic Strategies. Chemical Reviews 105:12, pages 4406-4440.
Crossref
Crossref
Philipp Hess, Lai Nguyen, John Aasen, Myra Keogh, Jane Kilcoyne, Pearse McCarron & Tore Aune. (2005) Tissue distribution, effects of cooking and parameters affecting the extraction of azaspiracids from mussels, Mytilus edulis, prior to analysis by liquid chromatography coupled to mass spectrometry. Toxicon 46:1, pages 62-71.
Crossref
Crossref
Amparo Alfonso, Yolanda Román, Mercedes R. Vieytes, Katsuya Ofuji, Masayuki Satake, Takeshi Yasumoto & Luis M. Botana. (2005) Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes. Biochemical Pharmacology 69:11, pages 1627-1636.
Crossref
Crossref
Masaki Kita & Daisuke Uemura. (2005) Iminium Alkaloids from Marine Invertebrates: Structure, Biological Activity, and Biogenesis. Chemistry Letters 34:4, pages 454-459.
Crossref
Crossref
K. C. Nicolaou & Scott A. Snyder. (2005) Chasing Molecules That Were Never There: Misassigned Natural Products and the Role of Chemical Synthesis in Modern Structure Elucidation. Angewandte Chemie International Edition 44:7, pages 1012-1044.
Crossref
Crossref
K. C. Nicolaou & Scott A. Snyder. (2005) Die Jagd auf Moleküle, die nie existiert haben: Falsch zugeordnete Naturstoffstrukturen und die Rolle der chemischen Synthese in der modernen Strukturaufklärung. Angewandte Chemie 117:7, pages 1036-1069.
Crossref
Crossref
Takeshi YASUMOTO. (2005) Chemistry, etiology, and food chain dynamics of marine toxins. Proceedings of the Japan Academy, Series B 81:2, pages 43-51.
Crossref
Crossref
Paulo Vale. (2004) Is there a risk of human poisoning by azaspiracids from shellfish harvested at the Portuguese coast?. Toxicon 44:8, pages 943-947.
Crossref
Crossref
Patrizia Ciminiello & Ernesto Fattorusso. (2004) Shellfish Toxins − Chemical Studies on Northern Adriatic Mussels. European Journal of Organic Chemistry 2004:12, pages 2533-2551.
Crossref
Crossref
Yuichi Ishikawa & Shigeru Nishiyama. (2004) Synthesis of the BCD ring system of azaspiracid: construction of the trispiro ring structure by the thioether approach. Tetrahedron Letters 45:2, pages 351-354.
Crossref
Crossref
Mary Lehane, Marı́a José Fidalgo Sáez, Ana Braña Magdalena, Isabel Ruppén Cañás, Mónica Dı́az Sierra, Brett Hamilton, Ambrose Furey & Kevin J James. (2004) Liquid chromatography—multiple tandem mass spectrometry for the determination of ten azaspiracids, including hydroxyl analogues in shellfish. Journal of Chromatography A 1024:1-2, pages 63-70.
Crossref
Crossref
Rich G Carter, T.Campbell Bourland, Xiao-Ti Zhou & Melissa A Gronemeyer. (2003) Controlling influences in bisspiroketal formation: synthesis of the ABC ring system of azaspiracid. Tetrahedron 59:45, pages 8963-8974.
Crossref
Crossref
Mónica Díaz Sierra, Ambrose Furey, Brett Hamilton, Mary Lehane & Kevin J. James. (2003) Elucidation of the fragmentation pathways of azaspiracids, using electrospray ionisation, hydrogen/deuterium exchange, and multiple-stage mass spectrometry. Journal of Mass Spectrometry 38:11, pages 1178-1186.
Crossref
Crossref
Pearl K. S. Blay, Stephan Brombacher & Dietrich A. Volmer. (2003) Studies on azaspiracid biotoxins. III. Instrumental validation for rapid quantification of AZA 1 in complex biological matrices. Rapid Communications in Mass Spectrometry 17:18, pages 2153-2159.
Crossref
Crossref
Makoto Sasaki, Yuko Iwamuro, Jyunichi Nemoto & Masato Oikawa. (2003) Studies toward the total synthesis of azaspiracids: synthesis of the FGHI ring domain. Tetrahedron Letters 44:33, pages 6199-6201.
Crossref
Crossref
Ambrose Furey, Cian Moroney, Ana Braña Magdalena, Maria José Fidalgo Saez, Mary Lehane & Kevin J. James. (2003) Geographical, Temporal, and Species Variation of the Polyether Toxins, Azaspiracids, in Shellfish. Environmental Science & Technology 37:14, pages 3078-3084.
Crossref
Crossref
Yuzuru Shimizu. (2003) Microalgal metabolites. Current Opinion in Microbiology 6:3, pages 236-243.
Crossref
Crossref
Kevin J. James, Monica Diaz Sierra, Mary Lehane, Ana Braña Magdalena & Ambrose Furey. (2003) Detection of five new hydroxyl analogues of azaspiracids in shellfish using multiple tandem mass spectrometry. Toxicon 41:3, pages 277-283.
Crossref
Crossref
Kevin J James, Cian Moroney, Cilian Roden, Masayuki Satake, Takeshi Yasumoto, Mary Lehane & Ambrose Furey. (2003) Ubiquitous ‘benign’ alga emerges as the cause of shellfish contamination responsible for the human toxic syndrome, azaspiracid poisoning. Toxicon 41:2, pages 145-151.
Crossref
Crossref
Stephan Brombacher, Suzanne Edmonds & Dietrich A. Volmer. (2002) Studies on azaspiracid biotoxins. II. Mass spectral behavior and structural elucidation of azaspiracid analogs. Rapid Communications in Mass Spectrometry 16:24, pages 2306-2316.
Crossref
Crossref
Dietrich A. Volmer, Stephan Brombacher & Bob Whitehead. (2002) Studies on azaspiracid biotoxins. I. Ultrafast high-resolution liquid chromatography/mass spectrometry separations using monolithic columns. Rapid Communications in Mass Spectrometry 16:24, pages 2298-2305.
Crossref
Crossref
Yolanda Román, Amparo Alfonso, M.Carmen Louzao, Laura A de la Rosa, Francisco Leira, Juan M Vieites, Mercedes R Vieytes, Katsuya Ofuji, Masayuki Satake, Takeshi Yasumoto & Luis M Botana. (2002) Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets. Cellular Signalling 14:8, pages 703-716.
Crossref
Crossref
Kevin J James, Ambrose Furey, Mary Lehane, Hanne Ramstad, Tore Aune, Peter Hovgaard, Steven Morris, Wendy Higman, Masayuki Satake & Takeshi Yasumoto. (2002) First evidence of an extensive northern European distribution of azaspiracid poisoning (AZP) toxins in shellfish. Toxicon 40:7, pages 909-915.
Crossref
Crossref
Rich G. Carter, David E. Graves, Melissa A. Gronemeyer & Gregory S. Tschumper. (2002)
Synthesis of the ABC Ring System of Azaspiracid. 2. A Systematic Study into the Effect of C
16
and C
17
Substitution on Bis-spirocyclization
. Organic Letters 4:13, pages 2181-2184.
Crossref
Crossref
Rich G. Carter, T. Campbell Bourland & David E. Graves. (2002) Synthesis of the ABC Ring System of Azaspiracid. 1. Effect of D Ring Truncation on Bis-spirocyclization. Organic Letters 4:13, pages 2177-2179.
Crossref
Crossref
M. Lehane, A. Braña-Magdalena, C. Moroney, A. Furey & K.J. James. (2002) Liquid chromatography with electrospray ion trap mass spectrometry for the determination of five azaspiracids in shellfish. Journal of Chromatography A 950:1-2, pages 139-147.
Crossref
Crossref
Ambrose Furey, Ana Bra?a-Magdalena, Mary Lehane, Cian Moroney, Kevin J. James, Masayuki Satake & Takeshi Yasumoto. (2002) Determination of azaspiracids in shellfish using liquid chromatography/tandem electrospray mass spectrometry. Rapid Communications in Mass Spectrometry 16:3, pages 238-242.
Crossref
Crossref
Emiko Ito, Masayuki Satake, Katsuya Ofuji, Morihiro Higashi, Kenichi Harigaya, Terry McMahon & Takeshi Yasumoto. (2002) Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels. Toxicon 40:2, pages 193-203.
Crossref
Crossref
K. C. Nicolaou, Wenyuan Qian, Federico Bernal, Noriaki Uesaka, Petri M. Pihko & Jürgen Hinrichs. (2001) Synthesis of the ABCD Ring System of Azaspiracid. Angewandte Chemie 113:21, pages 4192-4195.
Crossref
Crossref
Craig J. Forsyth, Junliang Hao & Josep Aiguade. (2001) Synthesis of the (+)‐C26–C40 Domain of the Azaspiracids by a Novel Double Intramolecular Hetero‐Michael Addition Strategy. Angewandte Chemie 113:19, pages 3775-3779.
Crossref
Crossref