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Original Articles

A Freshwater Clam (Corbicula fluminea) Extract Improves Cholesterol Metabolism in Rats Fed on a High-Cholesterol Diet

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Pages 2566-2571 | Received 17 Apr 2008, Accepted 01 Jul 2008, Published online: 22 May 2014

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Yu-Wei Chang, Chun-Che Lin & Wen-Chieh Sung. (2018) Studies on the Development of Small Abalone (Haliotis diversicolor supertexta) Essence and its Antioxidative Properties. Journal of Aquatic Food Product Technology 27:6, pages 733-748.
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Takeshi Chijimatsu, Miki Umeki, Satoru Kobayashi, Yutaro Kataoka, Koji Yamada, Hiroaki Oda & Satoshi Mochizuki. (2015) Dietary freshwater clam (Corbicula fluminea) extract suppresses accumulation of hepatic lipids and increases in serum cholesterol and aminotransferase activities induced by dietary chloretone in rats. Bioscience, Biotechnology, and Biochemistry 79:7, pages 1155-1163.
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Daeun Kim, Fumiaki Hanzawa, Shumin Sun, Thomas Laurent, Saiko Ikeda, Miki Umeki, Satoshi Mochizuki & Hiroaki Oda. (2021) Delayed Meal Timing, a Breakfast Skipping Model, Increased Hepatic Lipid Accumulation and Adipose Tissue Weight by Disintegrating Circadian Oscillation in Rats Fed a High-Cholesterol Diet. Frontiers in Nutrition 8.
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Nicole Zacharias, Iris Löckener, Sarah M. Essert, Esther Sib, Gabriele Bierbaum, Thomas Kistemann & Christiane Schreiber. (2021) Antibiotic-Resistant Bacteria in Clams—A Study on Mussels in the River Rhine. Antibiotics 10:5, pages 571.
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Zhaoshuo Yu, Guanzhen Gao, Huiqin Wang, Lijing Ke, Jianwu Zhou, Pingfan Rao, Tianbao Chen, Zhangwen Peng, Jianqiao Zou & Sihao Luo. (2020) Identification of protein-polysaccharide nanoparticles carrying hepatoprotective bioactives in freshwater clam (Corbicula fluminea Muller) soup. International Journal of Biological Macromolecules 151, pages 781-786.
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Jing-Jen Lin, Yeuk-Chuen Liu, Chun-Ju Chang, Min-Hsiung Pan, Mong-Fong Lee & Bonnie Sun Pan. (2018) Hepatoprotective mechanism of freshwater clam extract alleviates non-alcoholic fatty liver disease: elucidated in vitro and in vivo models . Food & Function 9:12, pages 6315-6325.
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Yi-Chi Peng, Fwu-LinYang, Yi-Maun Subeq, Chin-Chieh Tien & Ru-Ping Lee. (2017) Freshwater clam extract supplementation improves wound healing by decreasing the tumor necrosis factor ? level in blood . Journal of the Science of Food and Agriculture 97:4, pages 1193-1199.
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Ningbo Liao, Jianjun Zhong, Ronghua Zhang, Xingqian Ye, Yanjun Zhang, Wenjun Wang, Yuexia Wang, Shiguo Chen, Donghong Liu & Ruihai Liu. (2016) Protein-Bound Polysaccharide from Corbicula fluminea Inhibits Cell Growth in MCF-7 and MDA-MB-231 Human Breast Cancer Cells. PLOS ONE 11:12, pages e0167889.
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Sheng Chia Huang, Jing Jen Lin, Mong Fong Lee, Yeuk Chuen Liu & Bonnie Sun Pan. (2016) Freshwater clam extracts alleviate dyslipidaemia of tilapia fed a high-fat diet as an animal model. Journal of Functional Foods 25, pages 559-567.
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Thomas Laurent, Yuji Okuda, Takeshi Chijimatsu, Miki Umeki, Satoru Kobayashi, Yutaro Kataoka, Iwao Tatsuguchi, Satoshi Mochizuki & Hiroaki Oda. (2013) Freshwater Clam Extract Ameliorates Triglyceride and Cholesterol Metabolism through the Expression of Genes Involved in Hepatic Lipogenesis and Cholesterol Degradation in Rats. Evidence-Based Complementary and Alternative Medicine 2013, pages 1-10.
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Ningbo Liao, Shiguo Chen, Xingqian Ye, Jianjun Zhong, Nian Wu, Shilei Dong, Bo Yang & Donghong Liu. (2013) Antioxidant and anti-tumor activity of a polysaccharide from freshwater clam, Corbicula fluminea. Food & Function 4:4, pages 539.
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Takeshi Chijimatsu, Miki Umeki, Yutaro Kataoka, Satoru Kobayashi, Koji Yamada, Hiroaki Oda & Satoshi Mochizuki. (2013) Lipid components prepared from a freshwater Clam (Corbicula fluminea) extract ameliorate hypercholesterolaemia in rats fed high-cholesterol diet. Food Chemistry 136:2, pages 328-334.
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Zwe‐Ling Kong, Siauo Chi Yu, Shu Ai Dai, Cha‐Chung Tu, Min‐Hsiung Pan & Yeuk‐Chuen Liu. (2011) Polyoxygenated Sterols from Freshwater Clam. Helvetica Chimica Acta 94:5, pages 892-896.
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Yu-Hsin Lin, Jenn-Shou Tsai, Lang-Bang Hung & Bonnie Sun Pan. (2011) Plasma lipid regulatory effect of compounded freshwater clam hydrolysate and Gracilaria insoluble dietary fibre. Food Chemistry 125:2, pages 397-401.
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Takeshi Chijimatsu, Miki Umeki, Yuji Okuda, Koji Yamada, Hiroaki Oda & Satoshi Mochizuki. (2010) The fat and protein fractions of freshwater clam ( Corbicula fluminea ) extract reduce serum cholesterol and enhance bile acid biosynthesis and sterol excretion in hypercholesterolaemic rats fed a high-cholesterol diet . British Journal of Nutrition 105:4, pages 526-534.
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Yu-Hsin Lin, Jenn-Shou Tsai, Lang-Bang Hung & Bonnie Sun Pan. (2010) Hypocholesterolemic effect of compounded freshwater clam protein hydrolysate and Gracilaria. Food Chemistry 123:2, pages 395-399.
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Takeshi Chijimatsu, Iwao Tatsuguchi, Hiroaki Oda & Satoshi Mochizuki. (2009) A Freshwater Clam ( Corbicula fluminea ) Extract Reduces Cholesterol Level and Hepatic Lipids in Normal Rats and Xenobiotics-Induced Hypercholesterolemic Rats . Journal of Agricultural and Food Chemistry 57:8, pages 3108-3112.
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