Advanced search
Publication Cover
Bioscience, Biotechnology, and Biochemistry Volume 72, 2008 - Issue 10
Journal homepage
1,092
Views
92
CrossRef citations to date
0
Altmetric
Original Articles

Isolation and Characterization of a Novel Equol-Producing Bacterium from Human Feces

Shin-ichiro YOKOYAMADepartment of Applied Microbiology, Gifu Prefectural Research Institute for Bioengineering
&
Tohru SUZUKIThe United Graduate School of Agricultural Science, Gifu University
Pages 2660-2666 | Received 12 May 2008, Accepted 27 Jun 2008, Published online: 22 May 2014

Citations (92)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (9)

Saied A. Aboushanab, Shaimaa M. Khedr, Irina F. Gette, Irina G. Danilova, Natalia A. Kolberg, Gokare A. Ravishankar, Ranga Rao Ambati & Elena G. Kovaleva. (2023) Isoflavones derived from plant raw materials: bioavailability, anti-cancer, anti-aging potentials, and microbiome modulation. Critical Reviews in Food Science and Nutrition 63:2, pages 261-287.
Read now
Sudeep Ghimire, Nicole M. Cady, Peter Lehman, Stephanie R. Peterson, Shailesh K. Shahi, Faraz Rashid, Shailendra Giri & Ashutosh K. Mangalam. (2022) Dietary Isoflavones Alter Gut Microbiota and Lipopolysaccharide Biosynthesis to Reduce Inflammation. Gut Microbes 14:1.
Read now
Xiaoying Wang, Baiyan Chen, Xiang Fang, Qingping Zhong, Zhenlin Liao, Jie Wang, Xuejiao Wu, Yuhao Ma, Pengzhen Li, Xiaoxuan Feng & Li Wang. (2022) Soy isoflavone-specific biotransformation product S-equol in the colon: physiological functions, transformation mechanisms, and metabolic regulatory pathways. Critical Reviews in Food Science and Nutrition 0:0, pages 1-29.
Read now
Ángela Peirotén, Daniel Bravo & José M. Landete. (2020) Bacterial metabolism as responsible of beneficial effects of phytoestrogens on human health. Critical Reviews in Food Science and Nutrition 60:11, pages 1922-1937.
Read now
Simon Vlad Luca, Irina Macovei, Alexandra Bujor, Anca Miron, Krystyna Skalicka-Woźniak, Ana Clara Aprotosoaie & Adriana Trifan. (2020) Bioactivity of dietary polyphenols: The role of metabolites. Critical Reviews in Food Science and Nutrition 60:4, pages 626-659.
Read now
Kaeko Murota, Yoshimasa Nakamura & Mariko Uehara. (2018) Flavonoid metabolism: the interaction of metabolites and gut microbiota. Bioscience, Biotechnology, and Biochemistry 82:4, pages 600-610.
Read now
J. M. Landete, J. Arqués, M. Medina, P. Gaya, B. de Las Rivas & R. Muñoz. (2016) Bioactivation of Phytoestrogens: Intestinal Bacteria and Health. Critical Reviews in Food Science and Nutrition 56:11, pages 1826-1843.
Read now
Annett Braune & Michael Blaut. (2016) Bacterial species involved in the conversion of dietary flavonoids in the human gut . Gut Microbes 7:3, pages 216-234.
Read now
Yasuhiro Abiru, Tomomi Ueno & Shigeto Uchiyama. (2013) Isolation and characterization of novel S-equol-producing bacteria from brines of stinky tofu, a traditional fermented soy food in Taiwan. International Journal of Food Sciences and Nutrition 64:8, pages 936-943.
Read now

Articles from other publishers (83)

Baskar Balakrishnan, David LuckeyKerry Wright, John M. Davis, Jun ChenVeena Taneja. (2023) Eggerthella lenta augments preclinical autoantibody production and metabolic shift mimicking senescence in arthritis . Science Advances 9:35.
Crossref
M. Leonor Fernández-Murga, Fernando Gil-Ortiz, Lucía Serrano-García & Antonio Llombart-Cussac. (2023) A New Paradigm in the Relationship between Gut Microbiota and Breast Cancer: β-glucuronidase Enzyme Identified as Potential Therapeutic Target. Pathogens 12:9, pages 1086.
Crossref
Keith Dufault-Thompson, Brantley Hall & Xiaofang Jiang. (2022) Taxonomic distribution and evolutionary analysis of the equol biosynthesis gene cluster. BMC Genomics 23:1.
Crossref
Bowei Zhang, Yunhui Zhang, Xiaolong Xing & Shuo Wang. (2022) Health benefits of dietary polyphenols: insight into interindividual variability in absorption and metabolism. Current Opinion in Food Science 48, pages 100941.
Crossref
Hanbit Song, Pyung-Gang Lee, Junyeob Kim, Joonwon Kim, Sang-Hyuk Lee, Hyun Kim, Uk-Jae Lee, Jin Young Kim, Eun-Jung Kim & Byung-Gee Kim. (2022) Regioselective One-Pot Synthesis of Hydroxy-(S)-Equols Using Isoflavonoid Reductases and Monooxygenases and Evaluation of the Hydroxyequol Derivatives as Selective Estrogen Receptor Modulators and Antioxidants. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Yoshimi Niwano, Hidetsugu Kohzaki, Midori Shirato, Shunichi Shishido & Keisuke Nakamura. (2022) Putative Mechanisms Underlying the Beneficial Effects of Polyphenols in Murine Models of Metabolic Disorders in Relation to Gut Microbiota. Current Issues in Molecular Biology 44:3, pages 1353-1375.
Crossref
Lindsay M. Leonard, Mun Sun Choi & Tzu-Wen L. Cross. (2022) Maximizing the Estrogenic Potential of Soy Isoflavones through the Gut Microbiome: Implication for Cardiometabolic Health in Postmenopausal Women. Nutrients 14:3, pages 553.
Crossref
Jelena Cvejić, Milica Atanacković Krstonošić, Mira Mikulić & Uroš Miljić. 2022. Nutraceutical and Functional Food Components. Nutraceutical and Functional Food Components 243 312 .
R. García-Villalba, A. González-Sarrías, J.A. Giménez-Bastida, M.V. Selma, J.C. Espín & F.A. Tomás-Barberán. 2022. Comprehensive Gut Microbiota. Comprehensive Gut Microbiota 149 175 .
Sebastian Tobias Soukup, Dominic Alexander Stoll, Nicolas Danylec, Alena Schoepf, Sabine Emma Kulling & Melanie Huch. (2021) Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia. Foods 10:11, pages 2741.
Crossref
Li-Wen Huang, Tzu-Ching Huang, Yu-Chen Hu, Bau-Shan Hsieh, Hsiao-Ling Cheng, Pu-Rong Chiu & Kee-Lung Chang. (2021) S-Equol Protects Chondrocytes against Sodium Nitroprusside-Caused Matrix Loss and Apoptosis through Activating PI3K/Akt Pathway. International Journal of Molecular Sciences 22:13, pages 7054.
Crossref
Yingyu Guo, Lichao Zhao, Xiang Fang, Qingping Zhong, Huijun Liang, Wenou Liang & Li Wang. (2021) Isolation and identification of a human intestinal bacterium capable of daidzein conversion. FEMS Microbiology Letters 368:8.
Crossref
Elizabeth A Rettedal, Bolaji L Ilesanmi‐Oyelere, Nicole C Roy, Jane Coad & Marlena C Kruger. (2021) The Gut Microbiome Is Altered in Postmenopausal Women With Osteoporosis and Osteopenia. JBMR Plus 5:3.
Crossref
Rafidah Hod, Sandra Maniam & Nurul Huda Mohd Nor. (2021) A Systematic Review of the Effects of Equol (Soy Metabolite) on Breast Cancer. Molecules 26:4, pages 1105.
Crossref
Małgorzata Makarewicz, Iwona Drożdż, Tomasz Tarko & Aleksandra Duda-Chodak. (2021) The Interactions between Polyphenols and Microorganisms, Especially Gut Microbiota. Antioxidants 10:2, pages 188.
Crossref
Henrique Silva. (2021) The Vascular Effects of Isolated Isoflavones—A Focus on the Determinants of Blood Pressure Regulation. Biology 10:1, pages 49.
Crossref
Maria V. Selma, Francisco A. Tomás‐Barberán, Maria Romo‐Vaquero, Adrian Cortés‐Martín & Juan C. Espín. 2020. Dietary Polyphenols. Dietary Polyphenols 497 531 .
Ahkam Saddam Seyed Hameed, Parkash Singh Rawat, Xiangfeng Meng & Weifeng Liu. (2020) Biotransformation of dietary phytoestrogens by gut microbes: A review on bidirectional interaction between phytoestrogen metabolism and gut microbiota. Biotechnology Advances 43, pages 107576.
Crossref
Ze-Yu Wu, Li-Xuan Sang & Bing Chang. (2020) Isoflavones and inflammatory bowel disease. World Journal of Clinical Cases 8:11, pages 2081-2091.
Crossref
Wenou Liang, Lichao Zhao, Jingfeng Zhang, Xiang Fang, Qingping Zhong, Zhenlin Liao, Jie Wang, Yingyu Guo, Huijun Liang & Li Wang. (2020) Colonization Potential to Reconstitute a Microbe Community in Pseudo Germ-Free Mice After Fecal Microbe Transplant From Equol Producer. Frontiers in Microbiology 11.
Crossref
Adrián Cortés‐Martín, María Victoria Selma, Francisco Abraham Tomás‐Barberán, Antonio González‐Sarrías & Juan Carlos Espín. (2020) Where to Look into the Puzzle of Polyphenols and Health? The Postbiotics and Gut Microbiota Associated with Human Metabotypes. Molecular Nutrition & Food Research 64:9.
Crossref
Nicole Cady, Stephanie R. Peterson, Samantha N. Freedman & Ashutosh K. Mangalam. (2020) Beyond Metabolism: The Complex Interplay Between Dietary Phytoestrogens, Gut Bacteria, and Cells of Nervous and Immune Systems. Frontiers in Neurology 11.
Crossref
Toshio Niwa, Haruna Akiyama, Madoka Echikawa, Shin-ichiro Yokoyama, Mika Mochizuki & Toshihiko Osawa. (2020) Equol Inhibits Mushroom Tyrosinase <i>in Vitro</i> through Tight Binding. Biological and Pharmaceutical Bulletin 43:3, pages 550-553.
Crossref
Filomena Nazzaro, Florinda Fratianni, Vincenzo De Feo, Alberto Battistelli, Adriano Gomes Da Cruz & Raffaele Coppola. 2020. Probiotic and Prebiotics in Foods: Challenges, Innovations and Advances. Probiotic and Prebiotics in Foods: Challenges, Innovations and Advances 35 89 .
Toshio Niwa, Shin-ichiro Yokoyama, Mika Mochizuki & Toshihiko Osawa. (2019) Curcumin metabolism by human intestinal bacteria in vitro. Journal of Functional Foods 61, pages 103463.
Crossref
Yuan Heng, Min Jung Kim, Hye Jeong Yang, Suna Kang & Sunmin Park. (2019) Lactobacillus intestinalis efficiently produces equol from daidzein and chungkookjang, short-term fermented soybeans. Archives of Microbiology 201:8, pages 1009-1017.
Crossref
Baltasar Mayo, Lucía Vázquez & Ana Belén Flórez. (2019) Equol: A Bacterial Metabolite from The Daidzein Isoflavone and Its Presumed Beneficial Health Effects. Nutrients 11:9, pages 2231.
Crossref
Cheryl S. Rosenfeld. (2019) Effects of Phytoestrogens on the Developing Brain, Gut Microbiota, and Risk for Neurobehavioral Disorders. Frontiers in Nutrition 6.
Crossref
Flórez, Vázquez, Rodríguez, Redruello & Mayo. (2019) Transcriptional Regulation of the Equol Biosynthesis Gene Cluster in Adlercreutzia equolifaciens DSM19450T. Nutrients 11:5, pages 993.
Crossref
Victoria J. Vieira-Potter, Tzu-Wen L. Cross, Kelly S. Swanson, Saurav J. Sarma, Zhentian Lei, Lloyd W. Sumner & Cheryl S. Rosenfeld. (2018) Soy-Induced Fecal Metabolome Changes in Ovariectomized and Intact Female Rats: Relationship with Cardiometabolic Health. Scientific Reports 8:1.
Crossref
Pyung-Gang Lee, Uk-Jae Lee, Hanbit Song, Kwon-Young Choi & Byung-Gee Kim. (2018) Recent advances in the microbial hydroxylation and reduction of soy isoflavones. FEMS Microbiology Letters 365:19.
Crossref
Yuika Kawada, Tomoko Goshima, Rie Sawamura, Shin-ichiro Yokoyama, Emiko Yanase, Toshio Niwa, Akio Ebihara, Mizuho Inagaki, Keiichi Yamaguchi, Kazuo Kuwata, Yuta Kato, Osamu Sakurada & Tohru Suzuki. (2018) Daidzein reductase of Eggerthella sp. YY7918, its octameric subunit structure containing FMN/FAD/4Fe-4S, and its enantioselective production of R-dihydroisoflavones. Journal of Bioscience and Bioengineering 126:3, pages 301-309.
Crossref
Jeong Eun Kwon, Jaewon Lim, Inhye Kim, Donghyuk Kim & Se Chan Kang. (2018) Isolation and identification of new bacterial stains producing equol from Pueraria lobata extract fermentation. PLOS ONE 13:2, pages e0192490.
Crossref
Naice E.S. Monteiro, Lívia D. Queirós, Danielle B. Lopes, Adriana O. Pedro & Gabriela A. Macedo. (2018) Impact of microbiota on the use and effects of isoflavones in the relief of climacteric symptoms in menopausal women – A review. Journal of Functional Foods 41, pages 100-111.
Crossref
Colette Shortt, Oliver Hasselwander, Alexandra Meynier, Arjen Nauta, Estefanía Noriega Fernández, Peter Putz, Ian Rowland, Jonathan Swann, Jessica Türk, Joan Vermeiren & Jean-Michel Antoine. (2017) Systematic review of the effects of the intestinal microbiota on selected nutrients and non-nutrients. European Journal of Nutrition 57:1, pages 25-49.
Crossref
A. Braune & M. Blaut. (2018) Evaluation of inter-individual differences in gut bacterial isoflavone bioactivation in humans by PCR-based targeting of genes involved in equol formation. Journal of Applied Microbiology 124:1, pages 220-231.
Crossref
Jin-hua Tao, Min Zhao, Shu Jiang, Xue-lian Pu & Xiao-yan Wei. (2018) Comparative metabolism of two major compounds in Fructus Corni extracts by gut microflora from normal and chronic nephropathy rats in vitro by UPLC-Q-TOF/MS. Journal of Chromatography B 1073, pages 170-176.
Crossref
Pyung-Gang Lee, Joonwon Kim, Eun-Jung Kim, Sang-Hyuk Lee, Kwon-Young Choi, Romas J. Kazlauskas & Byung-Gee Kim. (2017) Biosynthesis of (−)-5-Hydroxy-equol and 5-Hydroxy-dehydroequol from Soy Isoflavone, Genistein Using Microbial Whole Cell Bioconversion. ACS Chemical Biology 12:11, pages 2883-2890.
Crossref
Luc?a V?zquez, Luc?a Guadamuro, Froil?n Giganto, Baltasar Mayo & Ana B. Fl?rez. (2017) Development and Use of a Real-Time Quantitative PCR Method for Detecting and Quantifying Equol-Producing Bacteria in Human Faecal Samples and Slurry Cultures. Frontiers in Microbiology 8.
Crossref
Baltasar Mayo, Lucía Guadamuro, Ana Belén Flórez & Susana Delgado. 2017. Exploring the Nutrition and Health Benefits of Functional Foods. Exploring the Nutrition and Health Benefits of Functional Foods 223 253 .
Motoi TamuraYosuke MatsuoHiroyuki NakagawaChigusa HoshiSachiko Hori. (2017) Isolation of a Quercetin-metabolizing Bacterium 19 – 20 from Human Feces. Food Science and Technology Research 23:1, pages 145-150.
Crossref
Danielle B. Lopes, Lívia D. de Queirós, Amanda R.A. de Ávila, Naice E.S. Monteiro & Gabriela A. Macedo. 2017. Food Bioconversion. Food Bioconversion 55 93 .
Jelena Hogervorst Cvejić, Milica Atanacković Krstonošić, Mira Bursać & Uroš Miljić. 2017. Nutraceutical and Functional Food Components. Nutraceutical and Functional Food Components 203 258 .
Bárbara S. Rocha, Carla Nunes & João Laranjinha. (2016) Tuning constitutive and pathological inflammation in the gut via the interaction of dietary nitrate and polyphenols with host microbiome. The International Journal of Biochemistry & Cell Biology 81, pages 393-402.
Crossref
Yoshie Nagata, Yukiko Sugiyama, Fumimasa Fukuta, Akio Takayanagi, Naoya Masumori, Taiji Tsukamoto, Hiroshi Akasaka, Hirofumi Ohnishi, Shigeyuki Saitoh, Tetsuji Miura, Kaoru Moriyama, Hirokazu Tsuji, Hideyuki Akaza & Mitsuru Mori. (2016) Relationship of serum levels and dietary intake of isoflavone, and the novel bacterium Slackia sp. strain NATTS with the risk of prostate cancer: a case–control study among Japanese men. International Urology and Nephrology 48:9, pages 1453-1460.
Crossref
Pyung-Gang Lee, Joonwon Kim, Eun-Jung Kim, EunOk Jung, Bishnu Prasad Pandey & Byung-Gee Kim. (2016) P212A Mutant of Dihydrodaidzein Reductase Enhances ( S )-Equol Production and Enantioselectivity in a Recombinant Escherichia coli Whole-Cell Reaction System . Applied and Environmental Microbiology 82:7, pages 1992-2002.
Crossref
Eunji Lee & Tae-Ho Park. (2016) Isoflavones and biotransformed dihydrodaidzein in hairy roots of Korean wild arrowroot. Journal of Plant Biotechnology 43:1, pages 125-131.
Crossref
Yuika KAWADA, Shinichiro YOKOYAMA, Emiko YANASE, Toshio NIWA & Tohru SUZUKI. (2016) The production of <i>S</i>-equol from daidzein is associated with a cluster of three genes in <i>Eggerthella</i> sp. YY7918. Bioscience of Microbiota, Food and Health 35:3, pages 113-121.
Crossref
Dong-Hyun Kim. (2015) Gut Microbiota-Mediated Drug-Antibiotic Interactions. Drug Metabolism and Disposition 43:10, pages 1581-1589.
Crossref
Aleksandra Duda-Chodak, Tomasz Tarko, Paweł Satora & Paweł Sroka. (2015) Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review. European Journal of Nutrition 54:3, pages 325-341.
Crossref
Fatemeh Rafii. (2015) The Role of Colonic Bacteria in the Metabolism of the Natural Isoflavone Daidzin to Equol. Metabolites 5:1, pages 56-73.
Crossref
Mirjana Rajilić-Stojanović & Willem M. de Vos. (2014) The first 1000 cultured species of the human gastrointestinal microbiota. FEMS Microbiology Reviews 38:5, pages 996-1047.
Crossref
Yukiko Sugiyama, Yoshie Nagata, Fumimasa Fukuta, Akio Takayanagi, Naoya Masumori, Taiji Tsukamoto, Hiroshi Akasaka, Hirofumi Ohnishi, Shigeyuki Saito, Tetsuji Miura, Kaoru Moriyama, Hirokazu Tsuji, Hideyuki Akaza & Mitsuru Mori. (2014) Counts of Slackia sp. strain NATTS in Intestinal Flora are Correlated to Serum Concentrations of Equol both in Prostate Cancer Cases and Controls in Japanese Men. Asian Pacific Journal of Cancer Prevention 15:6, pages 2693-2697.
Crossref
Yi-Shiou Chiou, Jia-Ching Wu, Qingrong Huang, Fereidoon Shahidi, Ying-Jan Wang, Chi-Tang Ho & Min-Hsiung Pan. (2014) Metabolic and colonic microbiota transformation may enhance the bioactivities of dietary polyphenols. Journal of Functional Foods 7, pages 3-25.
Crossref
Claudio Gardana, Enrica Canzi & Paolo Simonetti. (2014) R(-)-O-desmethylangolensin is the main enantiomeric form of daidzein metabolite produced by human in vitro and in vivo. Journal of Chromatography B 953-954, pages 30-37.
Crossref
Mandeep K. Virk-Baker, Stephen Barnes, Helen Krontiras & Tim R. Nagy. (2014) S-(−)equol producing status not associated with breast cancer risk among low isoflavone-consuming US postmenopausal women undergoing a physician-recommended breast biopsy. Nutrition Research 34:2, pages 116-125.
Crossref
Thomas Clavel, Patricia Lepage & Cédric Charrier. 2014. The Prokaryotes. The Prokaryotes 201 238 .
Juan Manuel Sánchez-Calvo, Manuel Antonio Rodríguez-Iglesias, José M. G. Molinillo & Francisco A. Macías. (2013) Soy isoflavones and their relationship with microflora: beneficial effects on human health in equol producers. Phytochemistry Reviews 12:4, pages 979-1000.
Crossref
Maddalena Rossi, Alberto Amaretti, Alan Leonardi, Stefano Raimondi, Marta Simone & Andrea Quartieri. (2013) Potential Impact of Probiotic Consumption on the Bioactivity of Dietary Phytochemicals. Journal of Agricultural and Food Chemistry, pages 130924093716009.
Crossref
Wanyang Liu, Miyako Tanabe, Kouji H. Harada & Akio Koizumi. (2013) Levels of urinary isoflavones and lignan polyphenols in Japanese women. Environmental Health and Preventive Medicine 18:5, pages 394-400.
Crossref
Mariko Uehara. (2013) Isoflavone metabolism and bone-sparing effects of daidzein-metabolites. Journal of Clinical Biochemistry and Nutrition 52:3, pages 193-201.
Crossref
Thomas Clavel & Job O. Mapesa. 2013. Natural Products. Natural Products 2433 2463 .
Dana Shor, Thozhukat Sathyapalan, Stephen L. Atkin & Natalie J. Thatcher. (2012) Does equol production determine soy endocrine effects?. European Journal of Nutrition 51:4, pages 389-398.
Crossref
Hirokazu Tsuji, Kaoru Moriyama, Koji Nomoto & Hideyuki Akaza. (2012) Identification of an Enzyme System for Daidzein-to-Equol Conversion in Slackia sp. Strain NATTS. Applied and Environmental Microbiology 78:4, pages 1228-1236.
Crossref
Fatemeh Rafii, John B. Sutherland, Brad M. Bridges, Miseon Park & Michael R. Adams. (2012) Relationship of Dietary Soy Protein to Daidzein Metabolism by Cultures of Intestinal Microfloras from Monkeys. Food and Nutrition Sciences 03:02, pages 267-273.
Crossref
红蕾 张. (2012) Advances in Isolating of Isoflavone Biotransforming Bacteria and Cloning of Genes Encoding Relative Biotransforming Enzymes. Bioprocess 02:02, pages 98-104.
Crossref
Shin-ichiro Yokoyama, Kenshiro Oshima, Izumi Nomura, Masahira Hattori & Tohru Suzuki. (2011) Complete Genomic Sequence of the O -Desmethylangolensin-Producing Bacterium Clostridium rRNA Cluster XIVa Strain SY8519, Isolated from Adult Human Intestine . Journal of Bacteriology 193:19, pages 5568-5569.
Crossref
Shin-ichiro Yokoyama, Kenshiro Oshima, Izumi Nomura, Masahira Hattori & Tohru Suzuki. (2011) Complete Genomic Sequence of the Equol-Producing Bacterium Eggerthella sp. Strain YY7918, Isolated from Adult Human Intestine. Journal of Bacteriology 193:19, pages 5570-5571.
Crossref
M. Andrea Azcárate-PerilMichael Sikes & José M. Bruno-Bárcena. (2011) The intestinal microbiota, gastrointestinal environment and colorectal cancer: a putative role for probiotics in prevention of colorectal cancer?. American Journal of Physiology-Gastrointestinal and Liver Physiology 301:3, pages G401-G424.
Crossref
Richard L Jackson, Jeffrey S Greiwe & Richard J Schwen. (2011) Emerging evidence of the health benefits of S-equol, an estrogen receptor β agonist. Nutrition Reviews 69:8, pages 432-448.
Crossref
Lucie Sosvorová, Petra Lanková, Marie Bičíková, Elena A. Prokudina, Nawaf Al Maharik & Oldřich Lapčík. (2011) ELISA for free S-equol in human urine. Czech Journal of Food Sciences 29:1, pages 57-64.
Crossref
Richard L. Jackson, Jeffrey S. Greiwe, Pankaj B. Desai & Richard J. Schwen. (2011) Single-dose and steady-state pharmacokinetic studies of S-equol, a potent nonhormonal, estrogen receptor β-agonist being developed for the treatment of menopausal symptoms. Menopause 18:2, pages 185-193.
Crossref
Takayuki Minekawa, Akira Kambegawa, Kumiko Shindome, Hiroshi Ohkuma, Katsushi Abe, Hiroaki Maekawa & Hidetoshi Arakawa. (2011) Development of Bioluminescent Enzyme Immunoassay for S-Equol Using Firefly Luciferase and Its Application to the Assessment of Equol-Producer Status. CHEMICAL & PHARMACEUTICAL BULLETIN 59:1, pages 84-87.
Crossref
Yoshikazu Shimada, Masayuki Takahashi, Norihiro Miyazawa, Tadaaki Ohtani, Yasuhiro Abiru, Shigeto Uchiyama & Haretsugu Hishigaki. (2011) Identification of Two Novel Reductases Involved in Equol Biosynthesis in Lactococcus Strain 20?92. Journal of Molecular Microbiology and Biotechnology 21:3-4, pages 160-172.
Crossref
Yoshikazu Shimada, Setsuko Yasuda, Masayuki Takahashi, Takashi Hayashi, Norihiro Miyazawa, Ikutaro Sato, Yasuhiro Abiru, Shigeto Uchiyama & Haretsugu Hishigaki. (2010) Cloning and Expression of a Novel NADP(H)-Dependent Daidzein Reductase, an Enzyme Involved in the Metabolism of Daidzein, from Equol-Producing Lactococcus Strain 20-92 . Applied and Environmental Microbiology 76:17, pages 5892-5901.
Crossref
Mihyang Kim, E. Neil G. Marsh, Soo-Un Kim & Jaehong Han. (2010) Conversion of (3 S ,4 R )-Tetrahydrodaidzein to (3 S )-Equol by THD Reductase: Proposed Mechanism Involving a Radical Intermediate . Biochemistry 49:26, pages 5582-5587.
Crossref
Kenneth D.R. Setchell & Carlo Clerici. (2010) Equol: History, Chemistry, and Formation. The Journal of Nutrition 140:7, pages 1355S-1362S.
Crossref
Shin-ichiro Yokoyama, Toshio Niwa, Toshihiko Osawa & Tohru Suzuki. (2009) Characterization of an O-desmethylangolensin-producing bacterium isolated from human feces. Archives of Microbiology 192:1, pages 15-22.
Crossref
Selin Bolca, Ciska Wyns, Sam Possemiers, Herman Depypere, Denis De Keukeleire, Marc Bracke, Willy Verstraete & Arne Heyerick. (2009) Cosupplementation of Isoflavones, Prenylflavonoids, and Lignans Alters Human Exposure to Phytoestrogen-Derived 17β-Estradiol Equivalents1–3. The Journal of Nutrition 139:12, pages 2293-2300.
Crossref
Toshio Niwa, Shin-Ichiro Yokoyama & Toshihiko Osawa. (2009) Preparation of soy isoflavonoids for the production of anti-equol monoclonal antibody. Phytochemistry Letters 2:4, pages 220-222.
Crossref
Mihyang Kim, Su-Il Kim, Jaehong Han, Xiu-Ling Wang, Dae-Geun Song & Soo-Un Kim. (2009) Stereospecific Biotransformation of Dihydrodaidzein into (3 S )-Equol by the Human Intestinal Bacterium Eggerthella Strain Julong 732 . Applied and Environmental Microbiology 75:10, pages 3062-3068.
Crossref
L. Kolios, S. Sehmisch, F. Daub, T. Rack, M. Tezval, K. M. Stuermer & E. K. Stuermer. 2009. Chirurgisches Forum und DGAV Forum 2009. Chirurgisches Forum und DGAV Forum 2009 305 307 .
Mi-Hyang Kim, Jae-Hong Han & Soo-Un Kim. (2008) Isoflavone Daidzein: Chemistry and Bacterial Metabolism. Journal of Applied Biological Chemistry 51:6, pages 253-261.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.