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Bioscience, Biotechnology, and Biochemistry Volume 72, 2008 - Issue 11
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Original Articles

Improvement of L-Lactate Production by CYB2 Gene Disruption in a Recombinant Saccharomyces cerevisiae Strain under Low pH Condition

Aki OOKUBODepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
,
Takashi HIRASAWADepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
,
Katsunori YOSHIKAWADepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
,
Keisuke NAGAHISADepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
,
Chikara FURUSAWADepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
&
Hiroshi SHIMIZUDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University
Pages 3063-3066 | Received 16 Jul 2008, Accepted 06 Aug 2008, Published online: 22 May 2014

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Yuma Ito, Takashi Hirasawa & Hiroshi Shimizu. (2014) Metabolic engineering of Saccharomyces cerevisiae to improve succinic acid production based on metabolic profiling. Bioscience, Biotechnology, and Biochemistry 78:1, pages 151-159.
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Michael Sauer, Danilo Porro, Diethard Mattanovich & Paola Branduardi. (2010) 16 years research on lactic acid production with yeast – ready for the market?. Biotechnology and Genetic Engineering Reviews 27:1, pages 229-256.
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Articles from other publishers (17)

Masato Sone, Kantawat Navanopparatsakul, Shunsuke Takahashi, Chikara Furusawa & Takashi Hirasawa. (2023) Loss of function of Hog1 improves glycerol assimilation in Saccharomyces cerevisiae. World Journal of Microbiology and Biotechnology 39:10.
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Li Sun, Quanwei Zhang, Xiao Kong, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Rodrigo Ledesma-Amaro, Jian Chen & Long Liu. (2023) Highly efficient neutralizer-free l-malic acid production using engineered Saccharomyces cerevisiae. Bioresource Technology 370, pages 128580.
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Qiangqiang Sun, Bin Dong, Dandan Yang, Jing Yu, Tianhao Ren, Tianxu Wang, Lianjuan Yang, Yang Lu & Chang Su. (2022) Zcf24, a zinc‐finger transcription factor, is required for lactate catabolism and inhibits commensalism in Candida albicans . Molecular Microbiology 119:1, pages 112-125.
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Nurzhan Kuanyshev, Christopher V. Rao, Bruce Dien & Yong‐Su Jin. (2020) Domesticating a food spoilage yeast into an organic acid‐tolerant metabolic engineering host: Lactic acid production by engineered Zygosaccharomyces bailii . Biotechnology and Bioengineering 118:1, pages 372-382.
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Sophie Lajus, Simon Dusséaux, Jonathan Verbeke, Coraline Rigouin, Zhongpeng Guo, Maria Fatarova, Floriant Bellvert, Vinciane Borsenberger, Mélusine Bressy, Jean-Marc Nicaud, Alain Marty & Florence Bordes. (2020) Engineering the Yeast Yarrowia lipolytica for Production of Polylactic Acid Homopolymer. Frontiers in Bioengineering and Biotechnology 8.
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Cristiane C.K. Mayerhofer, Ayodeji Awoyemi, Johannes R. Hov, Marius Trøseid & Kaspar Broch. (2019) Reply: Potential risk associated with direct modulation of the gut flora in patients with heart failure. ESC Heart Failure 6:3, pages 557-558.
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Jung-Hoon Bae, Hyun-Jin Kim, Mi-Jin Kim, Bong Hyun Sung, Jae-Heung Jeon, Hyun-Soon Kim, Yong-Su Jin, Dae-Hyuk Kweon & Jung-Hoon Sohn. (2018) Direct fermentation of Jerusalem artichoke tuber powder for production of l -lactic acid and d -lactic acid by metabolically engineered Kluyveromyces marxianus. Journal of Biotechnology 266, pages 27-33.
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Hiroshi Shimizu, Chikara Furusawa, Takashi Hirasawa, Katsunori Yoshikawa, Yoshihiro Toya, Tomokazu Shirai & Fumio Matsuda. 2017. Applied Bioengineering. Applied Bioengineering 213 236 .
Khyati K. Dave & Narayan S. Punekar. (2015) Expression of Lactate Dehydrogenase in Aspergillus niger for L-Lactic Acid Production. PLOS ONE 10:12, pages e0145459.
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Takashi Hirasawa, Masakado Takekuni, Katsunori Yoshikawa, Aki Ookubo, Chikara Furusawa & Hiroshi Shimizu. (2013) Genome-wide identification of the targets for genetic manipulation to improve l-lactate production by Saccharomyces cerevisiae by using a single-gene deletion strain collection. Journal of Biotechnology 168:2, pages 185-193.
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Yoshihiro Ida, Takashi Hirasawa, Chikara Furusawa & Hiroshi Shimizu. (2013) Utilization of Saccharomyces cerevisiae recombinant strain incapable of both ethanol and glycerol biosynthesis for anaerobic bioproduction. Applied Microbiology and Biotechnology 97:11, pages 4811-4819.
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Ping Liu & Laura R. Jarboe. (2012) METABOLIC ENGINEERING OF BIOCATALYSTS FOR CARBOXYLIC ACIDS PRODUCTION. Computational and Structural Biotechnology Journal 3:4, pages e201210011.
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Katsunori Yoshikawa, Chikara Furusawa, Takashi Hirasawa & Hiroshi Shimizu. 2012. Systems Metabolic Engineering. Systems Metabolic Engineering 57 81 .
Takashi Hirasawa, Chikara Furusawa & Hiroshi Shimizu. (2010) Saccharomyces cerevisiae and DNA microarray analyses: what did we learn from it for a better understanding and exploitation of yeast biotechnology?. Applied Microbiology and Biotechnology 87:2, pages 391-400.
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Takashi Hirasawa, Aki Ookubo, Katsunori Yoshikawa, Keisuke Nagahisa, Chikara Furusawa, Hideki Sawai & Hiroshi Shimizu. (2009) Investigating the effectiveness of DNA microarray analysis for identifying the genes involved in l-lactate production by Saccharomyces cerevisiae. Applied Microbiology and Biotechnology 84:6, pages 1149-1159.
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Siraje Arif Mahmud, Keisuke Nagahisa, Takashi Hirasawa, Katsunori Yoshikawa, Kengo Ashitani & Hiroshi Shimizu. (2009) Effect of trehalose accumulation on response to saline stress in Saccharomyces cerevisiae . Yeast 26:1, pages 17-30.
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. (1990) Current awareness on yeast. Yeast 26:5, pages 303-310.
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