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Bioscience, Biotechnology, and Biochemistry Volume 73, 2009 - Issue 8
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Original Articles

Genetic Engineering of Candida utilis Yeast for Efficient Production of L-Lactic Acid

Shigehito IKUSHIMACentral Laboratories for Frontier Technology, KIRIN Holdings Co., Ltd.
,
Toshio FUJIICentral Laboratories for Frontier Technology, KIRIN Holdings Co., Ltd.
,
Osamu KOBAYASHICentral Laboratories for Frontier Technology, KIRIN Holdings Co., Ltd.
,
Satoshi YOSHIDACentral Laboratories for Frontier Technology, KIRIN Holdings Co., Ltd.
&
Aruto YOSHIDACentral Laboratories for Frontier Technology, KIRIN Holdings Co., Ltd.
Pages 1818-1824 | Received 13 Mar 2009, Accepted 09 May 2009, Published online: 22 May 2014

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Ernesta Augustiniene, Egle Valanciene, Paulius Matulis, Michail Syrpas, Ilona Jonuskiene & Naglis Malys. (2022) Bioproduction of l- and d-lactic acids: advances and trends in microbial strain application and engineering. Critical Reviews in Biotechnology 42:3, pages 342-360.
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Hideyuki TAMAKAWA, Yasuyuki TOMITA, Aki YOKOYAMA, Yuki KONOEDA, Shigehito IKUSHIMA & Satoshi YOSHIDA. (2013) Metabolomic and Transcriptomic Analysis for Rate-Limiting Metabolic Steps in Xylose Utilization by Recombinant Candida utilis . Bioscience, Biotechnology, and Biochemistry 77:7, pages 1441-1448.
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Hideyuki TAMAKAWA, Shigehito IKUSHIMA & Satoshi YOSHIDA. (2011) Ethanol Production from Xylose by a Recombinant Candida utilis Strain Expressing Protein-Engineered Xylose Reductase and Xylitol Dehydrogenase. Bioscience, Biotechnology, and Biochemistry 75:10, pages 1994-2000.
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Michael Sauer, Danilo Porro, Diethard Mattanovich & Paola Branduardi. (2010) 16 years research on lactic acid production with yeast – ready for the market?. Biotechnology and Genetic Engineering Reviews 27:1, pages 229-256.
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Qiburi He, Gaowa Gong, Tingting Wan, He Hu & Peng Yu. (2023) An integrated transcriptomic and metabolic phenotype analysis to uncover the metabolic characteristics of a genetically engineered Candida utilis strain expressing δ-zein gene. Frontiers in Microbiology 14.
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Bin Zhang, Rongqun Li, Lihua Yu, Chenchen Wu, Zhe Liu, Fengyan Bai, Bo Yu & Limin Wang. (2023) l -Lactic Acid Production via Sustainable Neutralizer-Free Route by Engineering Acid-Tolerant Yeast Pichia kudriavzevii . Journal of Agricultural and Food Chemistry 71:29, pages 11131-11140.
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Abidemi Oluranti Ojo & Olga de Smidt. (2023) Lactic Acid: A Comprehensive Review of Production to Purification. Processes 11:3, pages 688.
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Christoph Buerth, Denis Tielker & Joachim F. Ernst. (2016) Candida utilis and Cyberlindnera (Pichia) jadinii: yeast relatives with expanding applications. Applied Microbiology and Biotechnology 100:16, pages 6981-6990.
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Khyati K. Dave & Narayan S. Punekar. (2015) Expression of Lactate Dehydrogenase in Aspergillus niger for L-Lactic Acid Production. PLOS ONE 10:12, pages e0145459.
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Ying Wang, Yukihiro Tashiro & Kenji Sonomoto. (2015) Fermentative production of lactic acid from renewable materials: Recent achievements, prospects, and limits. Journal of Bioscience and Bioengineering 119:1, pages 10-18.
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Bikram P. Upadhyaya, Linda C. DeVeaux & Lew P. Christopher. (2014) Metabolic engineering as a tool for enhanced lactic acid production. Trends in Biotechnology 32:12, pages 637-644.
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Hana Boňková, Michaela Osadská, Ján Krahulec, Veronika Lišková, Stanislav Stuchlík & Ján Turňa. (2014) Upstream regulatory regions controlling the expression of the Candida utilis maltase gene. Journal of Biotechnology 189, pages 136-142.
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Rita Pinheiro, Marlene Lopes, Isabel Belo & Manuel Mota. (2014) Candida utilis metabolism and morphology under increased air pressure up to 12bar. Process Biochemistry 49:3, pages 374-379.
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Fumitake Kurosaka & Hisahide Nishio. (2014) Two school children showed dyspnea after eating school meals including <i>Candida utilis</i> (alias: torula yeast), proved the blood <i>Candida utilis</i> IgE antibody, which is added as a flavor ingredient. Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology 28:5, pages 777-786.
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António Pacheco, Gabriel Talaia, Joana Sá-Pessoa, Daniela Bessa, Maria José Gonçalves, Roxana Moreira, Sandra Paiva, Margarida Casal & Odília Queirós. (2012) Lactic acid production in Saccharomyces cerevisiae is modulated by expression of the monocarboxylate transporters Jen1 and Ady2. FEMS Yeast Research 12:3, pages 375-381.
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Hideyuki Tamakawa, Shigehito Ikushima & Satoshi Yoshida. (2012) Efficient production of l-lactic acid from xylose by a recombinant Candida utilis strain. Journal of Bioscience and Bioengineering 113:1, pages 73-75.
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Arnold Demain & Sergio Sanchez. 2011. Fermentation Microbiology and Biotechnology, Third Edition. Fermentation Microbiology and Biotechnology, Third Edition 77 100 .
Mohamed Ali Abdel-Rahman, Yukihiro Tashiro & Kenji Sonomoto. (2011) Lactic acid production from lignocellulose-derived sugars using lactic acid bacteria: Overview and limits. Journal of Biotechnology 156:4, pages 286-301.
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Cuiling Pan, Yuxin Zhao, Shengfa F. Liao, Fu Chen, Shunyi Qin, Xianshi Wu, Hong Zhou & Kehe Huang. (2011) Effect of Selenium-Enriched Probiotics on Laying Performance, Egg Quality, Egg Selenium Content, and Egg Glutathione Peroxidase Activity. Journal of Agricultural and Food Chemistry 59:21, pages 11424-11431.
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Christoph Buerth, Clemens J. Heilmann, Frans M. Klis, Chris G. de Koster, Joachim F. Ernst & Denis Tielker. (2011) Growth-dependent secretome of Candida utilis. Microbiology 157:9, pages 2493-2503.
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Mark S. Ou, Lonnie O. Ingram & K. T. Shanmugam. (2010) l(+)-Lactic acid production from non-food carbohydrates by thermotolerant Bacillus coagulans. Journal of Industrial Microbiology & Biotechnology 38:5, pages 599-605.
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Danilo Porro, Brigitte Gasser, Tiziana Fossati, Michael Maurer, Paola Branduardi, Michael Sauer & Diethard Mattanovich. (2010) Production of recombinant proteins and metabolites in yeasts. Applied Microbiology and Biotechnology 89:4, pages 939-948.
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