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Original Articles

Clinical Pharmacokinetics of Cannabinoids

Pages 3-51 | Received 13 Apr 2002, Accepted 19 Jul 2002, Published online: 15 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

David J. Smith, Eric M. Serum, Thomas M. Winders, Bryan Neville, Grant R. Herges, Carl R. Dahlen & Kendall C. Swanson. (2023) Excretion and residue depletion of cannabinoids in beef cattle fed hempseed cake for 111 days. Food Additives & Contaminants: Part A 40:4, pages 552-565.
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Lidya Kebede, Seyedehsara Masoomi Dezfooli & Ali Seyfoddin. (2022) Medicinal cannabis pharmacokinetics and potential methods of delivery. Pharmaceutical Development and Technology 27:2, pages 202-214.
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Bernhard Beitzke & David W. Pate. (2021) A broader view on deriving a reference dose for THC traces in foods. Critical Reviews in Toxicology 51:8, pages 695-722.
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Paula Morales & Nadine Jagerovic. (2020) Novel approaches and current challenges with targeting the endocannabinoid system. Expert Opinion on Drug Discovery 15:8, pages 917-930.
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Articles from other publishers (28)

Sascha K Manier, Johannes Angert Valdiviezo, Aline C Vollmer, Niels Eckstein & Markus R Meyer. (2023) Analytical toxicology of the semi-synthetic cannabinoid hexahydrocannabinol studied in human samples, pooled human liver S9 fraction, rat samples and drug products using HPLC–HRMS-MS. Journal of Analytical Toxicology.
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Fran M. Gengo, Anna G. Mattle & Christopher C. RalyeaJr.Jr.. 2023. Medicinal Usage of Cannabis and Cannabinoids. Medicinal Usage of Cannabis and Cannabinoids 297 317 .
Samir Senapati, Ahmed Adel Ali Youssef, Corinne Sweeney, Chuntian Cai, Narendar Dudhipala & Soumyajit Majumdar. (2022) Cannabidiol Loaded Topical Ophthalmic Nanoemulsion Lowers Intraocular Pressure in Normotensive Dutch-Belted Rabbits. Pharmaceutics 14:12, pages 2585.
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Zak M. Whiting, Jiazhen Yin, Sara M. de la Harpe, Andrea J. Vernall & Natasha L. Grimsey. (2022) Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future. Trends in Pharmacological Sciences 43:9, pages 754-771.
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SulabhaSambhaji Lalsare. (2022) Cannabinoids: Legal aspects, pharmacology, phytochemistry, probable targets from biological system, and therapeutic potential. Asian Journal of Pharmaceutical Research and Health Care 14:3, pages 127.
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Jaderson V. Ferreira, Gisele A. Chaves, Mateus A. Batista, Lenir C. Correia, Lucilene R. Souza, Daniel C. Costa, Mariana P. Barcelos, Carlos Henrique Tomich de Paula da Silva, Carlton A. Taft & Lorane Izabel da Silva Hage-Melim. 2022. Research Topics in Bioactivity, Environment and Energy. Research Topics in Bioactivity, Environment and Energy 405 449 .
Godfrey D. Pearlson, Michael C. Stevens & Deepak Cyril D'Souza. (2021) Cannabis and Driving. Frontiers in Psychiatry 12.
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Jonas Carneiro Cruz, Luís Felippe Cabral Miranda & Maria Eugênia Costa Queiroz. (2021) Pipette tip micro‐solid phase extraction (octyl‐functionalized hybrid silica monolith) and ultra‐high‐performance liquid chromatography‐tandem mass spectrometry to determine cannabidiol and tetrahydrocannabinol in plasma samples. Journal of Separation Science 44:8, pages 1621-1632.
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Mark A. T. Blaskovich, Angela M. Kavanagh, Alysha G. Elliott, Bing Zhang, Soumya Ramu, Maite Amado, Gabrielle J. Lowe, Alexandra O. Hinton, Do Minh Thu Pham, Johannes Zuegg, Neil Beare, Diana Quach, Marc D. Sharp, Joe Pogliano, Ashleigh P. Rogers, Dena Lyras, Lendl Tan, Nicholas P. West, David W. Crawford, Marnie L. Peterson, Matthew Callahan & Michael Thurn. (2021) The antimicrobial potential of cannabidiol. Communications Biology 4:1.
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Rajiv Kumar Chaturvedi & Dinesh Chandra Agrawal. 2021. Medicinal Herbs and Fungi. Medicinal Herbs and Fungi 159 185 .
Paola Perin, Alex Mabou Tagne, Paolo Enrico, Franca Marino, Marco Cosentino, Roberto Pizzala & Cinzia Boselli. (2020) Cannabinoids, Inner Ear, Hearing, and Tinnitus: A Neuroimmunological Perspective. Frontiers in Neurology 11.
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Emily M. LaFrance, Nicholas C. Glodosky, Marcel Bonn-Miller & Carrie Cuttler. (2020) Short and Long-Term Effects of Cannabis on Symptoms of Post-Traumatic Stress Disorder. Journal of Affective Disorders 274, pages 298-304.
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Nevenka Kopjar, Nino Fuchs, Irena Brčić Karačonji, Suzana Žunec, Anja Katić, Goran Kozina & Ana Lucić Vrdoljak. (2020) High Doses of Δ9-Tetrahydrocannabinol Might Impair Irinotecan Chemotherapy: A Review of Potentially Harmful Interactions. Clinical Drug Investigation 40:9, pages 775-787.
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Ryan Gillies, Kendrick Lee, Sebastian Vanin, Steven R. Laviolette, Alison C. Holloway, Edith Arany & Daniel B. Hardy. (2020) Maternal exposure to Δ9-tetrahydrocannabinol impairs female offspring glucose homeostasis and endocrine pancreatic development in the rat. Reproductive Toxicology 94, pages 84-91.
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Dvora Izgelov, Eliyahu Shmoeli, Abraham J. Domb & Amnon Hoffman. (2020) The effect of medium chain and long chain triglycerides incorporated in self-nano emulsifying drug delivery systems on oral absorption of cannabinoids in rats. International Journal of Pharmaceutics 580, pages 119201.
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Camila Marchioni, Tatiana Manzini Vieira, Antônio Eduardo Miller Crotti, José Alexandre Crippa & Maria Eugênia Costa Queiroz. (2020) In-tube solid-phase microextraction with a dummy molecularly imprinted monolithic capillary coupled to ultra-performance liquid chromatography-tandem mass spectrometry to determine cannabinoids in plasma samples. Analytica Chimica Acta 1099, pages 145-154.
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Nino Fuchs, Alena Miljanić, Anja Katić, Nataša Brajenović, Vedran Micek, Radovan Fuchs & Irena Brčić Karačonji. (2019) Optimisation of a gas chromatography-mass spectrometry method for the simultaneous determination of tetrahydrocannabinol and its metabolites in rat urine. Archives of Industrial Hygiene and Toxicology 70:4, pages 325-331.
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Alexia Blake & Istok Nahtigal. (2019) The evolving landscape of cannabis edibles. Current Opinion in Food Science 28, pages 25-31.
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Beniamino Palmieri, Carmen Laurino & Maria Vadalà. (2019) Spontaneous, anecdotal, retrospective, open-label study on the efficacy, safety and tolerability of cannabis galenical preparation (Bedrocan). International Journal of Pharmacy Practice 27:3, pages 264-270.
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Jane Alcorn, Stephanie Vuong, Fang Wu, Blair Seifert & Andrew Lyon. 2019. Recent Advances in Cannabinoid Research. Recent Advances in Cannabinoid Research.
Nevenka Kopjar, Nino Fuchs, Suzana Žunec, Anja Mikolić, Vedran Micek, Goran Kozina, Ana Lucić Vrdoljak & Irena Brčić Karačonji. (2019) DNA Damaging Effects, Oxidative Stress Responses and Cholinesterase Activity in Blood and Brain of Wistar Rats Exposed to Δ9-Tetrahydrocannabinol. Molecules 24:8, pages 1560.
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Mohammad-Reza Ghovanloo, Noah Gregory Shuart, Janette Mezeyova, Richard A. Dean, Peter C. Ruben & Samuel J. Goodchild. (2018) Inhibitory effects of cannabidiol on voltage-dependent sodium currents. Journal of Biological Chemistry 293:43, pages 16546-16558.
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Davide Ferrari, Monica Manca, Simone Premaschi, Giuseppe Banfi & Massimo Locatelli. (2018) Toxicological investigation in blood samples from suspected impaired driving cases in the Milan area: Possible loss of evidence due to late blood sampling. Forensic Science International 288, pages 211-217.
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Ana Lucić Vrdoljak, Nino Fuchs, Anja Mikolić, Suzana Žunec, Irena Brčić Karačonji, Andreja Jurič, Ljerka Prester, Vedran Micek, Marijana Neuberg, Samir Čanović, Gordan Mršić & Nevenka Kopjar. (2018) Irinotecan and Δ9-Tetrahydrocannabinol Interactions in Rat Liver: A Preliminary Evaluation Using Biochemical and Genotoxicity Markers. Molecules 23:6, pages 1332.
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Jules A. A. C. Heuberger, Zheng Guan, Olubukayo-Opeyemi Oyetayo, Linda Klumpers, Paul D. Morrison, Tim L. Beumer, Joop M. A. van Gerven, Adam F. Cohen & Jan Freijer. (2014) Population Pharmacokinetic Model of THC Integrates Oral, Intravenous, and Pulmonary Dosing and Characterizes Short- and Long-term Pharmacokinetics. Clinical Pharmacokinetics 54:2, pages 209-219.
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Janet Bastard & Denise Tiran. (2009) Reprint of: Aromatherapy and massage for antenatal anxiety: Its effect on the fetus. Complementary Therapies in Clinical Practice 15:4, pages 230-233.
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Janet Bastard & Denise Tiran. (2006) Aromatherapy and massage for antenatal anxiety: Its effect on the fetus. Complementary Therapies in Clinical Practice 12:1, pages 48-54.
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C. H. Ashton, P. B. Moore, P. Gallagher & A. H. Young. (2016) Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. Journal of Psychopharmacology 19:3, pages 293-300.
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