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Original Articles

Long-Term Effect of Acetyl-L-Carnitine for Antiretroviral Toxic Neuropathy

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Pages 344-350 | Published online: 02 Feb 2015

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Giulia Di Stefano, Andrea Di Lionardo, Eleonora Galosi, Andrea Truini & Giorgio Cruccu. (2019) Acetyl-L-carnitine in painful peripheral neuropathy: a systematic review. Journal of Pain Research 12, pages 1341-1351.
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Marco Onofrj, Fausta Ciccocioppo, Sara Varanese, Antonio di Muzio, Menotti Calvani, Santina Chiechio, Maurizio Osio & Astrid Thomas. (2013) Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond. Expert Review of Neurotherapeutics 13:8, pages 925-936.
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Anne Maagaard & Dag Kvale. (2009) Long term adverse effects related to nucleoside reverse transcriptase inhibitors: Clinical impact of mitochondrial toxicity. Scandinavian Journal of Infectious Diseases 41:11-12, pages 808-817.
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Kevin Robertson, Kathy Kopnisky, James Hakim, Concepta Merry, Noeline Nakasujja, Colin Hall, Moussa Traore, Ned Sacktor, David Clifford, Charles Newton, Annelies Van Rie, Penny Holding, Janice Clements, Christine Zink, Jens Mielke, Mina Hosseinipour, Umesh Lalloo, Farida Amod, Christina Marra, Scott Evans, Jeff Liner & on behalf of the second Assessment of NeuroAIDS in Africa Conference Participants. (2008) Second assessment of NeuroAIDS in Africa. Journal of Neurovirology 14:2, pages 89-101.
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Maija Dambrova, Marina Makrecka-Kuka, Janis Kuka, Reinis Vilskersts, Didi Nordberg, Misty M. Attwood, Stefan Smesny, Zumrut Duygu Sen, An Chi Guo, Eponine Oler, Siyang Tian, Jiamin Zheng, David S. Wishart, Edgars Liepinsh & Helgi B. Schiöth. (2022) Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials. Pharmacological Reviews 74:3, pages 506-551.
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Cecilia Maldonado, Marta Vázquez & Pietro Fagiolino. (2020) Potential Therapeutic Role of Carnitine and Acetylcarnitine in Neurological Disorders. Current Pharmaceutical Design 26:12, pages 1277-1285.
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Teresa Paolucci, Giulia Piccinini, Sveva Maria Nusca, Gabriella Marsilli, Alice Mannocci, Giuseppe La Torre, Vincenzo Maria Saraceni, Maria Chiara Vulpiani & Ciro Villani. (2018) Efficacy of dietary supplement with nutraceutical composed combined with extremely-low-frequency electromagnetic fields in carpal tunnel syndrome. Journal of Physical Therapy Science 30:6, pages 777-784.
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Matthew W. T. Curran, Jaret Olson, Michael Morhart, Dory Sample & K. Ming Chan. (2016) Acetyl-L-carnitine (ALCAR) to enhance nerve regeneration in carpal tunnel syndrome: study protocol for a randomized, placebo-controlled trial. Trials 17:1.
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Sheyu Li, Xiang Chen, Qianrui Li, Juan Du, Zhimin Liu, Yongde Peng, Mian Xu, Qifu Li, Minxiang Lei, Changjiang Wang, Shaoxiong Zheng, Xiaojuan Zhang, Hongling Yu, Jinyu Shi, Shibing Tao, Ping Feng & Haoming Tian. (2016) Effects of acetyl‐L‐carnitine and methylcobalamin for diabetic peripheral neuropathy: A multicenter, randomized, double‐blind, controlled trial. Journal of Diabetes Investigation 7:5, pages 777-785.
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Bjørn Waagsbø, Asbjørn Svardal, Thor Ueland, Linn Landrø, Olav Øktedalen, Rolf K. Berge, Trude H. Flo, Pål Aukrust & Jan K. Damås. (2016) Low levels of short‐ and medium‐chain acylcarnitines in HIV‐infected patients. European Journal of Clinical Investigation 46:5, pages 408-417.
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Naveen Sankhyan, Rakesh Lodha, Suvasini Sharma, P. Ramesh Menon, Anita Choudhary, Sushil K. Kabra & Sheffali Gulati. (2014) Peripheral Neuropathy in Children on Stauvudine Therapy. The Indian Journal of Pediatrics 82:2, pages 136-139.
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Natalie Callander, Stephanie Markovina, Jens Eickhoff, Paul Hutson, Toby Campbell, Peiman Hematti, Ronald Go, Robert Hegeman, Walter Longo, Eliot Williams, Fotis Asimakopoulos & Shigeki Miyamoto. (2014) Acetyl-l-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network. Cancer Chemotherapy and Pharmacology 74:4, pages 875-882.
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Pru Thein, Gilda M. Kalinec, Channy Park & Federico Kalinec. (2014) In vitro assessment of antiretroviral drugs demonstrates potential for ototoxicity. Hearing Research 310, pages 27-35.
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Anna Rita Zuena, Chiara Giuli, Aldina Venerosi Pesciolini, Antonella Tramutola, Maria Antonietta Ajmone-Cat, Carlo Cinque, Giovanni Sebastiano Alemà, Angela Giovine, Gianfranco Peluso, Luisa Minghetti, Raffaella Nicolai, Gemma Calamandrei & Paola Casolini. (2013) Transplacental Exposure to AZT Induces Adverse Neurochemical and Behavioral Effects in a Mouse Model: Protection by L-Acetylcarnitine. PLoS ONE 8:2, pages e55753.
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Marco Vacante, Velia D’Agata, Massimo Motta, Giulia Malaguarnera, Antonio Biondi, Francesco Basile, Michele Malaguarnera, Caterina Gagliano, Filippo Drago & Salvatore Salamone. (2012) Centenarians and supercentenarians: a black swan. Emerging social, medical and surgical problems. BMC Surgery 12:S1.
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Mariano Malaguarnera. (2012) Carnitine derivatives. Current Opinion in Gastroenterology 28:2, pages 166-176.
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Haleh Rezaee, Hossein KhaliliJamshid Salamzadeh, Sirus Jafari & Alireza Abdollahi. (2012) Potential benefits of carnitine in HIV-positive patients. Future Virology 7:1, pages 73-83.
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Gary McCleane. (2010) Pain management in older people. Reviews in Clinical Gerontology 20:3, pages 183-192.
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Kevin Tan, Avindra Nath & Ahmet Hoke. 2010. Chemokine Receptors and NeuroAIDS. Chemokine Receptors and NeuroAIDS 51 85 .
Thierry Bordet & Rebecca M. Pruss. (2009) Targeting neuroprotection as an alternative approach to preventing and treating neuropathic pain. Neurotherapeutics 6:4, pages 648-662.
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C Herzmann, S.J Whiting, M Thomas, P. Byrne, M.A Johnson & M Youle. (2008) Pharmacokinetics of Acetyl-L-Carnitine Given in Single or Multiple Doses to HIV-1 Infected Patients with Toxic Peripheral Polyneuropathy. The Open AIDS Journal 2:1, pages 39-42.
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Mike Youle. (2007) Acetyl-L-Carnitine in HIV-Associated Antiretroviral Toxic Neuropathy. CNS Drugs 21:Supplement 1, pages 25-30.
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Alessandra Vanotti, Maurizio Osio, Enrico Mailland, Caterina Nascimbene, Elisa Capiluppi & Claudio Mariani. (2007) Overview on Pathophysiology and Newer Approaches to Treatment of Peripheral Neuropathies. CNS Drugs 21:Supplement 1, pages 3-12.
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David R Cornblath & Ahmet Hoke. (2006) Recent advances in HIV neuropathy. Current Opinion in Neurology 19:5, pages 446-450.
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