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Miscellaneous

Small-molecule, tubulin-binding compounds as vascular targeting agents

Pages 769-776 | Published online: 25 Feb 2005

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Wenlong Li, Ying Yin, Hong Yao, Wen Shuai, Honghao Sun, Shengtao Xu, Jie Liu, Hequan Yao, Zheying Zhu & Jinyi Xu. (2018) Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities. European Journal of Medicinal Chemistry 157, pages 1068-1080.
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Tianzhou Liu, Dawei Zhang, Wantong Song, Zhaohui Tang, Jiaming Zhu, Zhiming Ma, Xudong Wang, Xuesi Chen & Ti Tong. (2017) A poly(l-glutamic acid)-combretastatin A4 conjugate for solid tumor therapy: Markedly improved therapeutic efficiency through its low tissue penetration in solid tumor. Acta Biomaterialia 53, pages 179-189.
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Carmen Avendaño & J. Carlos Menéndez. 2015. Medicinal Chemistry of Anticancer Drugs. Medicinal Chemistry of Anticancer Drugs 359 390 .
Jin Zhang, Jing Zhou, Xiaomei Ren, Yanyan Diao, Honglin Li, Hualiang Jiang, Ke Ding & Duanqing Pei. (2010) A new diaryl urea compound, D181, induces cell cycle arrest in the G1 and M phases by targeting receptor tyrosine kinases and the microtubule skeleton. Investigational New Drugs 30:2, pages 490-507.
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Bernard L. Flynn, Gurmit S. Gill, Damian W. Grobelny, Jason H. Chaplin, Dharam Paul, Annabell F. Leske, Tina C. Lavranos, David K. Chalmers, Susan A. Charman, Edmund Kostewicz, David M. Shackleford, Julia Morizzi, Ernest Hamel, M. Katherine Jung & Gabriel Kremmidiotis. (2011) Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[ b ]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties . Journal of Medicinal Chemistry 54:17, pages 6014-6027.
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Sylvie Ducki, Grant Mackenzie, Ben Greedy, Simon Armitage, Jérémie Fournier Dit Chabert, Elizabeth Bennett, Jim Nettles, James P. Snyder & Nicholas J. Lawrence. (2009) Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones. Bioorganic & Medicinal Chemistry 17:22, pages 7711-7722.
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Carmen Avendaño & J. Carlos Menéndez. 2008. Medicinal Chemistry of Anticancer Drugs. Medicinal Chemistry of Anticancer Drugs 229 249 .
Susan L. Bane. 2008. The Role of Microtubules in Cell Biology, Neurobiology, and Oncology. The Role of Microtubules in Cell Biology, Neurobiology, and Oncology 259 279 .
Daniel J. Kerr, Ernest Hamel, M. Katherine Jung & Bernard L. Flynn. (2007) The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4. Bioorganic & Medicinal Chemistry 15:9, pages 3290-3298.
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S. Mahboobi, A. Sellmer & T. Beckers. 2006. 719 750 .
Matthias Gerlach, Eckhard Claus, Silke Baasner, Gilbert Müller, Emmanuel Polymeropoulos, Peter Schmidt, Eckhard Günther & Jürgen Engel. (2004) Design and Synthesis of a Focused Library of Novel Aryl‐ and Heteroaryl‐Ketopiperazides. Archiv der Pharmazie 337:12, pages 695-703.
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Henriette Gourdeau, Lorraine Leblond, Bettina Hamelin, Clemence Desputeau, Kelly Dong, Irenej Kianicka, Dominique Custeau, Chantal Boudreau, Lilianne Geerts, Sui-Xiong Cai, John Drewe, Denis Labrecque, Shailaja Kasibhatla & Ben Tseng. (2004) Antivascular and antitumor evaluation of 2-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-4 H -chromenes, a novel series of anticancer agents . Molecular Cancer Therapeutics 3:11, pages 1375-1384.
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Shailaja Kasibhatla, Henriette Gourdeau, Karen Meerovitch, John Drewe, Sanjeeva Reddy, Ling Qiu, Hong Zhang, Frederick Bergeron, David Bouffard, Quan Yang, John Herich, Serge Lamothe, Sui Xiong Cai & Ben Tseng. (2004) Discovery and mechanism of action of a novel series of apoptosis inducers with potential vascular targeting activity. Molecular Cancer Therapeutics 3:11, pages 1365-1374.
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