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Miscellaneous

New inhibitors of poly(ADP-ribose) polymerase and their potential therapeutic targets

Pages 1047-1071 | Published online: 25 Feb 2005

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Agostino Cilibrizzi, Giuseppe Floresta, Vincenzo Abbate & Maria Paola Giovannoni. (2019) iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 44-50.
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Marek Banasik, Todd Stedeford, Robert P. Strosznajder, Masanori Takehashi, Seigo Tanaka & Kunihiro Ueda. (2011) Inhibition of poly(ADP-ribose) polymerase-1 attenuates the toxicity of carbon tetrachloride. Journal of Enzyme Inhibition and Medicinal Chemistry 26:6, pages 883-889.
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Stefan Peukert & Uwe Schwahn. (2004) New inhibitors of poly(ADP-ribose) polymerase (PARP). Expert Opinion on Therapeutic Patents 14:11, pages 1531-1551.
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D. Dubner, M. del Rosario Pérez, S. Michelin, M. Bourguignon, P. Moreau, E. D. Carosella & P. Gisone. (2004) Pharmacological inhibition of DNA repair enzymes differentially modulates telomerase activity and apoptosis in two human leukaemia cell lines. International Journal of Radiation Biology 80:8, pages 593-605.
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Articles from other publishers (34)

Pulla Prudvi Raj, Kaviarasan Lakshmanan, Gowramma Byran, Kalirajan Rajagopal, Praveen Thaggikuppe Krishnamurthy & Divya Jyothi Palati. (2022) Recent PARP Inhibitor Advancements in Cancer Therapy: A Review. Current Enzyme Inhibition 18:2, pages 92-104.
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T.A. Kurgina, R.O. Anarbaev, M.V. Sukhanova & O.I. Lavrik. (2018) A rapid fluorescent method for the real-time measurement of poly(ADP-ribose) polymerase 1 activity. Analytical Biochemistry 545, pages 91-97.
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Yuliya V. Sherstyuk, Alexandra L. Zakharenko, Mikhail M. Kutuzov, Polina V. Chalova, Maria V. Sukhanova, Olga I. Lavrik, Vladimir N. Silnikov & Tatyana V. Abramova. (2016) A versatile strategy for the design and synthesis of novel ADP conjugates and their evaluation as potential poly(ADP-ribose) polymerase 1 inhibitors. Molecular Diversity 21:1, pages 101-113.
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Ю. В. Шерстюк, А.Л. Захаренко, М.М. Кутузов, М.В. Суханова, О.И. Лаврик, В. Н. Сильников & Т. В. Абрамова. (2017) СИНТЕЗ СЕРИИ АНАЛОГОВ NAD - ПОТЕНЦИАЛЬНЫХ ИНГИБИТОРОВ ПАРП 1 - С ИСПОЛЬЗОВАНИЕМ КОНЪЮГАТОВ ADP, ФУНКЦИОНАЛИЗИРОВАННЫХ ПО КОНЦЕВОЙ ФОСФАТНОЙ ГРУППЕ, "Биоорганическая химия". Биоорганическая химия:1, pages 88-96.
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Chandan Kumar, Nidhi Rani, Palanisamy Thanga Velan Lakshmi & Annamalai Arunachalam. (2017) A comprehensive look of poly(ADP-ribose) polymerase inhibition strategies and future directions for cancer therapy. Future Medicinal Chemistry 9:1, pages 37-60.
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Yu. V. Sherstyuk, A. L. Zakharenko, M. M. Kutuzov, M. V. Sukhanova, O. I. Lavrik, V. N. Silnikov & T. V. Abramova. (2017) Synthesis of a series of NAD+ analogues, potential inhibitors of PARP 1, using ADP conjugates functionalized at the terminal phosphate group. Russian Journal of Bioorganic Chemistry 43:1, pages 76-83.
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Adrian L. Schwan, Mohanad Gh. Shkoor & Irena Nikoloska. (2014) Introducing the Diels-Alder Reactivity of 2-Furanmethanethiol with Selected Maleic Acid Derivatives. HETEROCYCLES 88:2, pages 1603.
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Eun-Seok Park, Jun Chul Kang, Do-Hyun Kang, Yong Chang Jang, Kyu Yang Yi, Hun-Jong Chung, Jong Seok Park, Bokyung Kim, Zhong-Ping Feng & Hwa-Sup Shin. (2013) 5-AIQ inhibits H2O2-induced apoptosis through reactive oxygen species scavenging and Akt/GSK-3β signaling pathway in H9c2 cardiomyocytes. Toxicology and Applied Pharmacology 268:1, pages 90-98.
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Natisha Magan, Richard J. Isaacs & Kathryn M. Stowell. (2012) Treatment with the PARP-inhibitor PJ34 causes enhanced doxorubicin-mediated cell death in HeLa cells. Anti-Cancer Drugs 23:6, pages 627-637.
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Rupinder K. Sodhi, Nirmal Singh & Amteshwar S. Jaggi. (2010) Poly(ADP-ribose) polymerase-1 (PARP-1) and its therapeutic implications. Vascular Pharmacology 53:3-4, pages 77-87.
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Danila Branca, Mauro Cerretani, Philip Jones, Uwe Koch, Federica Orvieto, Maria Cecilia Palumbi, Michael Rowley, Carlo Toniatti & Ester Muraglia. (2009) Identification of aminoethyl pyrrolo dihydroisoquinolinones as novel poly(ADP-ribose) polymerase-1 inhibitors. Bioorganic & Medicinal Chemistry Letters 19:15, pages 4042-4045.
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Prakash G. Jagtap, Zhiyu Chen & Garry J. Southan. (2009) Chlorosulfonic acid-mediated cyclization of 4-phenyl-3-isocoumarincarboxylic acids and 4-phenyl-3-isoquinolinonecarboxylic acids: an efficient synthesis of 3-oxoindeno[2,1-c]isocoumarins and 3-oxoindeno[2,1-c]isoquinolinones. Tetrahedron Letters 50:18, pages 2057-2059.
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Wilna J. Moree, Phyllis Goldman, Anthony J. Demaggio, Erik Christenson, Dan Herendeen, John Eksterowicz, Edward A. Kesicki, David L. McElligott & Graham Beaton. (2008) Identification of ring-fused pyrazolo pyridin-2-ones as novel poly(ADP-ribose)polymerase-1 inhibitors. Bioorganic & Medicinal Chemistry Letters 18:18, pages 5126-5129.
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Nadezhda I. Ryabokon, Rose I. Goncharova, Gunars Duburs, Ronald Hancock & Joanna Rzeszowska-Wolny. (2008) Changes in poly(ADP-ribose) level modulate the kinetics of DNA strand break rejoining. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 637:1-2, pages 173-181.
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Prabal K. Chatterjee. (2007) Novel pharmacological approaches to the treatment of renal ischemia-reperfusion injury: a comprehensive review. Naunyn-Schmiedeberg's Archives of Pharmacology 376:1-2, pages 1-43.
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Kouji Hattori, Yoshiyuki Kido, Hirofumi Yamamoto, Junya Ishida, Akinori Iwashita & Kayoko Mihara. (2007) Rational design of conformationally restricted quinazolinone inhibitors of poly(ADP-ribose)polymerase. Bioorganic & Medicinal Chemistry Letters 17:20, pages 5577-5581.
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Rosanna Di Paola, Emanuela Mazzon, Carmelo Muià, Dino Terrana, Salvatore Greco, Domenico Britti, Domenico Santori, Giacomo Oteri, Giancarlo Cordasco & Salvatore Cuzzocrea. (2007) 5-aminoisoquinolin-1(2H)-one, a water-soluble poly (ADP-ribose) polymerase (PARP) inhibitor reduces the evolution of experimental periodontitis in rats. Journal of Clinical Periodontology 34:2, pages 95-102.
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Magda Lourda, Ioannis P. Trougakos & Efstathios S. Gonos. (2007) Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of clusterin/apolipoprotein J. International Journal of Cancer 120:3, pages 611-622.
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Junya Ishida, Hirofumi Yamamoto, Yoshiyuki Kido, Kazunori Kamijo, Kenji Murano, Hiroshi Miyake, Mitsuru Ohkubo, Takayoshi Kinoshita, Masaichi Warizaya, Akinori Iwashita, Kayoko Mihara, Nobuya Matsuoka & Kouji Hattori. (2006) Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling. Bioorganic & Medicinal Chemistry 14:5, pages 1378-1390.
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Nicola J. Curtin. 2006. Poly(ADP-Ribosyl)ation. Poly(ADP-Ribosyl)ation 218 233 .
Prabal K. Chatterjee & Christoph Thiemermann. 2006. Poly(ADP-Ribosyl)ation. Poly(ADP-Ribosyl)ation 164 183 .
Junya Ishida, Kouji Hattori, Hirofumi Yamamoto, Akinori Iwashita, Kayoko Mihara & Nobuya Matsuoka. (2005) 4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors. Bioorganic & Medicinal Chemistry Letters 15:19, pages 4221-4225.
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Prakash G. Jagtap, Erkan Baloglu, Garry J. Southan, Jon G. Mabley, Hongshan Li, Jing Zhou, John van Duzer, Andrew L. Salzman & Csaba Szabó. (2005) Discovery of Potent Poly(ADP-ribose) Polymerase-1 Inhibitors from the Modification of Indeno[1,2- c ]isoquinolinone . Journal of Medicinal Chemistry 48:16, pages 5100-5103.
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Nuno G. Oliveira, Matilde Castro, António S. Rodrigues, Isabel C. Gonçalves, Célia Martins, José M. Toscano Rico & José Rueff. (2005) Effect of poly(ADP-ribosyl)ation inhibitors on the genotoxic effects of the boron neutron capture reaction. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 583:1, pages 36-48.
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Marta Chevanne, Riccardo Caldini & Mario Del Rosso. (2017) Poly(ADP-ribosyl)ation, a molecular switch of transcription, shows an attractive relationship with urokinase expression. Thrombosis and Haemostasis 93:02, pages 220-227.
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Marc De Block, Christoph Verduyn, Dirk De Brouwer & Marc Cornelissen. (2004) Poly(ADP-ribose) polymerase in plants affects energy homeostasis, cell death and stress tolerance. The Plant Journal 41:1, pages 95-106.
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Salvatore Cuzzocrea, Emanuela Mazzon, Rosanna Di Paola, Tiziana Genovese, Nimesh S. A. Patel, Carmelo Muià, Michael D. Threadgill, Angelina De Sarro & Christoph Thiemermann. (2004) 5-Aminoisoquinolinone reduces colon injury by experimental colitis. Naunyn-Schmiedeberg's Archives of Pharmacology 370:6, pages 464-473.
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Elena Fonfria, Ian C B Marshall, Christopher D Benham, Izzy Boyfield, Jason D Brown, Kerstin Hill, Jane P Hughes, Stephen D Skaper & Shaun McNulty. (2004) TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase. British Journal of Pharmacology 143:1, pages 186-192.
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Dolores Podestá, Marı́a I. Garcı́a-Herreros, Joaquı́n J.B. Cannata, Andrés O.M. Stoppani & Silvia H. Fernández Villamil. (2004) Purification and properties of poly(ADP-ribose)polymerase from Crithidia fasciculata. Molecular and Biochemical Parasitology 135:2, pages 211-219.
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Karson S Putt & Paul J Hergenrother. (2004) An enzymatic assay for poly(ADP-ribose) polymerase-1 (PARP-1) via the chemical quantitation of NAD+: application to the high-throughput screening of small molecules as potential inhibitors. Analytical Biochemistry 326:1, pages 78-86.
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Prabal K. Chatterjee, Bristi E. Chatterjee, Helene Pedersen, Ahila Sivarajah, Michelle C. McDonald, Helder Mota-Filipe, Paul A.J. Brown, Keith N. Stewart, Salvatore Cuzzocrea, Michael D. Threadgill & Christoph Thiemermann. (2004) 5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion. Kidney International 65:2, pages 499-509.
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Ian A Clark & William B Cowden. (2003) The pathophysiology of falciparum malaria. Pharmacology & Therapeutics 99:2, pages 221-260.
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