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Harshita Krishnatreyya, Hemanga Hazarika, Achintya Saha, Santa Mandal, Nilutpal Sharma Bora, Sumit Kishor, Yangchen Doma Bhutia, Danswrang Goyary, Sanjeev Karmakar & Pronobesh Chattopadhyay. (2020) Amelioration from the ocular irritant Capsaicin: development and assessment of a Capsazepine in situ gel system for ocular delivery. Expert Opinion on Drug Delivery 17:6, pages 863-880.
Read now
Read now
Franciszek Saczewski & Łukasz Balewski. (2009) Biological activities of guanidine compounds. Expert Opinion on Therapeutic Patents 19:10, pages 1417-1448.
Read now
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Giovanni Appendino. (2006) Benzamide-type vanilloid (TRPV1) antagonists. Expert Opinion on Therapeutic Patents 16:4, pages 549-553.
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Articles from other publishers (27)
Gustavo José Vasco Pereira, Maurício Temotheo Tavares, Ricardo Alexandre Azevedo, Barbara Behr Martins, Micael Rodrigues Cunha, Rajesh Bhardwaj, Yara Cury, Vanessa Olzon Zambelli, Euzébio Guimarães Barbosa, Matthias A. Hediger & Roberto Parise-Filho. (2019) Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling. Bioorganic & Medicinal Chemistry 27:13, pages 2893-2904.
Crossref
Crossref
Aparna Shukla, Pooja Sharma, Om Prakash, Monika Singh, Komal Kalani, Feroz Khan, Dnyaneshwar Umrao Bawankule, Suaib Luqman & Santosh Kumar Srivastava. (2014) QSAR and Docking Studies on Capsazepine Derivatives for Immunomodulatory and Anti-Inflammatory Activity. PLoS ONE 9:7, pages e100797.
Crossref
Crossref
Nam‐Jung Kim, Fu‐Nan Li, Jin Hee Lee, Seul‐gi Park, Kyeojin Kim, Changjin Lim, Young Taek Han, Hwayoung Yun, Jong‐Wha Jung, Hyeung‐geun Park, Hee‐Doo Kim, Byoung Young Woo, Song Seok Shin, Sun‐Young Kim, Jin Kyu Choi, Yeon‐Su Jeong, Yanghui Park, Young‐Ho Park, Dae‐Duk Kim, Sun Choi & Young‐Ger Suh. (2012) Heterocycle‐linked Phenylbenzyl Amides as Novel TRPV1 Antagonists and Their TRPV1 Binding Modes: Constraint‐Induced Enhancement of In Vitro and In Vivo Activities. Chemistry – An Asian Journal 8:2, pages 400-409.
Crossref
Crossref
Alec D. Lebsack, Jason C. Rech, Bryan J. Branstetter, Natalie A. Hawryluk, Jeffrey E. Merit, Brett Allison, Raymond Rynberg, Johnathan Buma, Michele Rizzolio, Nadia Swanson, Hong Ao, Michael P. Maher, Michelle Herrmann, Jamie Freedman, Brian P. Scott, Lin Luo, Anindya Bhattacharya, Qi Wang, Sandra R. Chaplan, Alan D. Wickenden & J. Guy Breitenbucher. (2010) 1,2-Diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties. Bioorganic & Medicinal Chemistry Letters 20:23, pages 7142-7146.
Crossref
Crossref
Mark H. Norman. 2010. Accounts in Drug Discovery. Accounts in Drug Discovery
287
315
.
Alec D. Lebsack, Bryan J. Branstetter, Michael D. Hack, Wei Xiao, Matthew L. Peterson, Nadia Nasser, Michael P. Maher, Hong Ao, Anindya Bhattacharya, Mena Kansagara, Brian P. Scott, Lin Luo, Raymond Rynberg, Michele Rizzolio, Sandra R. Chaplan, Alan D. Wickenden & J. Guy Breitenbucher. (2009) Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 19:1, pages 40-46.
Crossref
Crossref
Nuria Tamayo, Hongyu Liao, Markian M. Stec, Xianghong Wang, Partha Chakrabarti, Dan Retz, Elizabeth M. Doherty, Sekhar Surapaneni, Rami Tamir, Anthony W. Bannon, Narender R. Gavva & Mark H. Norman. (2008) Design and Synthesis of Peripherally Restricted Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists. Journal of Medicinal Chemistry 51:9, pages 2744-2757.
Crossref
Crossref
Marı´a F. Dalence-Guzmán, Magnus Berglund, Staffan Skogvall & Olov Sterner. (2008) SAR studies of capsazepinoid bronchodilators. Part 1: The importance of the catechol moiety and aspects of the B-ring structure. Bioorganic & Medicinal Chemistry 16:5, pages 2499-2512.
Crossref
Crossref
Olivier Potterat & Matthias Hamburger. 2008. Natural Compounds as Drugs Volume I. Natural Compounds as Drugs Volume I
45
118
.
Martina Quintanar-Audelo, Asia Fernández-Carvajal, Wim Van Den Nest, Cristina Carreño, Antonio Ferrer-Montiel & Fernando Albericio. (2007) Design and Synthesis of Indole-Based Peptoids as Potent Noncompetitive Antagonists of Transient Receptor Potential Vanilloid 1. Journal of Medicinal Chemistry 50:24, pages 6133-6143.
Crossref
Crossref
Giovanni Appendino. 2007. Modern Alkaloids. Modern Alkaloids
73
109
.
Elizabeth M. Doherty, Christopher Fotsch, Anthony W. Bannon, Yunxin Bo, Ning Chen, Celia Dominguez, James Falsey, Narender R. Gavva, Jodie Katon, Thomas Nixey, Vassil I. Ognyanov, Liping Pettus, Robert M. Rzasa, Markian Stec, Sekhar Surapaneni, Rami Tamir, Jiawang Zhu, James J. S. Treanor & Mark H. Norman. (2007) Novel Vanilloid Receptor-1 Antagonists: 2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate. Journal of Medicinal Chemistry 50:15, pages 3515-3527.
Crossref
Crossref
Mark H. Norman, Jiawang Zhu, Christopher Fotsch, Yunxin Bo, Ning Chen, Partha Chakrabarti, Elizabeth M. Doherty, Narender R. Gavva, Nobuko Nishimura, Thomas Nixey, Vassil I. Ognyanov, Robert M. Rzasa, Markian Stec, Sekhar Surapaneni, Rami Tamir, Vellarkad N. Viswanadhan & James J. S. Treanor. (2007)
Novel Vanilloid Receptor-1 Antagonists: 1. Conformationally Restricted Analogues of
trans
-Cinnamides
. Journal of Medicinal Chemistry 50:15, pages 3497-3514.
Crossref
Crossref
Lei Tang, Yan Chen, Zili Chen, Peter M. Blumberg, Alan P. Kozikowski & Zaijie Jim Wang. (2007)
Antinociceptive Pharmacology of
N
-(4-Chlorobenzyl)-
N
′-(4-hydroxy-3-iodo-5-methoxybenzyl) Thiourea, a High-Affinity Competitive Antagonist of the Transient Receptor Potential Vanilloid 1 Receptor
. Journal of Pharmacology and Experimental Therapeutics 321:2, pages 791-798.
Crossref
Crossref
Abdellah Ech-Chahad, Lahboub Bouyazza & Giovanni Appendino. (2019) A Convenient Synthesis of 5′-Iodoresiniferatoxin (I-RTX). Natural Product Communications 1:12, pages 1934578X0600101.
Crossref
Crossref
Vassil I. Ognyanov, Chenera Balan, Anthony W. Bannon, Yunxin Bo, Celia Dominguez, Christopher Fotsch, Vijay K. Gore, Lana Klionsky, Vu V. Ma, Yi-Xin Qian, Rami Tamir, Xianghong Wang, Ning Xi, Shimin Xu, Dawn Zhu, Narender R. Gavva, James J. S. Treanor & Mark H. Norman. (2006)
Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1
H
-benzimidazoles
. Journal of Medicinal Chemistry 49:12, pages 3719-3742.
Crossref
Crossref
Giovanni AppendinoAlberto MinassiLuca BertonAniello Schiano MorielloMaria Grazia CascioLuciano De PetrocellisVincenzo Di Marzo. (2006) Oxyhomologues of Anandamide and Related Endolipids: Chemoselective Synthesis and Biological Activity. Journal of Medicinal Chemistry 49:7, pages 2333-2338.
Crossref
Crossref
Giovanni Appendino & Arpad Szallasi. 2006. Progress in Medicinal Chemistry Volume 44. Progress in Medicinal Chemistry Volume 44
145
180
.
Young-Ger Suh, Yong-Sil Lee, Kyung-Hoon Min, Ok-Hui Park, Jin-Kwan Kim, Ho-Sun Seung, Seung-Yong Seo, Bo-Young Lee, Yeon-Hee Nam, Kwang-Ok Lee, Hee-Doo Kim, Hyeung-Geun Park, Jeewoo Lee, Uhtaek Oh, Ju-Ok Lim, Sang-Uk Kang, Min-Jung Kil, Jae-yeon Koo, Song Seok Shin, Yung-Hyup Joo, Jin Kwan Kim, Yeon-Su Jeong, Sun-Young Kim & Young-Ho Park. (2005) Novel Potent Antagonists of Transient Receptor Potential Channel, Vanilloid Subfamily Member 1: Structure−Activity Relationship of 1,3-Diarylalkyl Thioureas Possessing New Vanilloid Equivalents. Journal of Medicinal Chemistry 48:18, pages 5823-5836.
Crossref
Crossref
Jeewoo Lee, Mi-Kyoung Jin, Sang-Uk Kang, Su Yeon Kim, Jiyoun Lee, Myoungyoup Shin, Jaemin Hwang, Sookhyun Cho, Yeon-Sil Choi, Hyun-Kyung Choi, Sung-Eun Kim, Young-Ger Suh, Yong-Sil Lee, Young-Ho Kim, Hee-Jin Ha, Attila Toth, Larry V. Pearce, Richard Tran, Tamas Szabo, Jacqueline D. Welter, Daniel J. Lundberg, Yun Wang, Jozsef Lazar, Vladimir A. Pavlyukovets, Matthew A. Morgan & Peter M. Blumberg. (2005) Analysis of structure–activity relationships for the ‘B-region’ of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 15:18, pages 4143-4150.
Crossref
Crossref
Giovanni AppendinoNives DaddarioAlberto MinassiAniello Schiano MorielloLuciano De PetrocellisVincenzo Di Marzo. (2005)
The Taming of Capsaicin. Reversal of the Vanilloid Activity of
N
-Acylvanillamines by Aromatic Iodination
. Journal of Medicinal Chemistry 48:14, pages 4663-4669.
Crossref
Crossref
Attila Tóth, Yun Wang, Noémi Kedei, Richard Tran, Larry V. Pearce, Sang-Uk Kang, Mi-Kyung Jin, Hyun-Kyung Choi, Jeewoo Lee & Peter M. Blumberg. (2005) Different vanilloid agonists cause different patterns of calcium response in CHO cells heterologously expressing rat TRPV1. Life Sciences 76:25, pages 2921-2932.
Crossref
Crossref
J. Guy Breitenbucher, Sandra R. Chaplan & Nicholas I. Carruthers. 2005. Annual Reports in Medicinal Chemistry Volume 40. Annual Reports in Medicinal Chemistry Volume 40
185
198
.
Giovanni Appendino, Alberto Minassi & Nives Daddario. (2005) Hot Cuisine as a Source of Anti-Inflammatory Drugs. Phytochemistry Reviews 4:1, pages 3-10.
Crossref
Crossref
Peter M. Blumberg, Derek C. Braun, Noemi Kedei, Jozsef Lazar, Vladimir Pavlyukovets & Larry V. Pearce. 2005. Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation. Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation
55
69
.
Jeewoo Lee, Su Yeon Kim, Jiyoun Lee, Myungsim Kang, Min-Jung Kil, Hyun-Kyung Choi, Mi-Kyung Jin, Yun Wang, Attila Toth, Larry V Pearce, Daniel J Lundberg, Richard Tran & Peter M Blumberg. (2004) Analysis of structure–activity relationships with the N-(3-acyloxy-2-benzylpropyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea template for vanilloid receptor 1 antagonism. Bioorganic & Medicinal Chemistry 12:13, pages 3411-3420.
Crossref
Crossref
Michele C. Jetter, Mark A. Youngman, James J. McNally, Sui-Po Zhang, Adrienne E. Dubin, Nadia Nasser & Scott L. Dax. (2004) N-Isoquinolin-5-yl-N′-aralkyl-urea and -amide antagonists of human vanilloid receptor 1. Bioorganic & Medicinal Chemistry Letters 14:12, pages 3053-3056.
Crossref
Crossref