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Targeting survivin in cancer: patent review

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Pages 1723-1737 | Published online: 18 Nov 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Cristina M Quintella, Heitor M Quintella, Mayla Rohweder & Guilherme M Quintella. (2020) Advances in patent applications related to cancer vaccine using CpG-ODN and OX40 association. Expert Opinion on Therapeutic Patents 30:4, pages 287-301.
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Kislay Roy, Rupinder K Kanwar, Subramanian Krishnakumar, Chun Hei Antonio Cheung & Jagat R Kanwar. (2015) Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model. International Journal of Nanomedicine 10, pages 1019-1043.
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Jagat R. Kanwar, Kislay Roy & Rupinder K. Kanwar. (2011) Chimeric aptamers in cancer cell-targeted drug delivery. Critical Reviews in Biochemistry and Molecular Biology 46:6, pages 459-477.
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Articles from other publishers (35)

Dariimaa Ganbat, Bat-Erdene Jugder, Lkhamaa Ganbat, Miki Tomoeda, Erdenetsogt Dungubat, Ambaga Miyegombo, Gantsetseg Garmaa, Yoshihisa Takahashi, Ryuji Fukuzawa, Ichiro Mori, Takayuki Shiomi, Akinori Nakata & Yasuhiko Tomita. (2022) Use of the Naphthoquinone YM155 (Sepantronium Bromide) in the Treatment of Cancer: A Systematic Review and Meta-Synthesis. Oncologie 24:2, pages 195-225.
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Man-Yu Chu, He-Cheng Huang, En-Ming Li & Li-Yan Xu. (2021) CypA: A Potential Target of Tumor Radiotherapy and/or Chemotherapy. Current Medicinal Chemistry 28:19, pages 3787-3802.
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Pooria Safarzadeh Kozani, Pouya Safarzadeh Kozani & Mohammad Tariq Malik. (2021) AS1411-functionalized delivery nanosystems for targeted cancer therapy. Exploration of Medicine.
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Sadia Ata, Atta Rasool, Atif Islam, Ismat Bibi, Muhammad Rizwan, Muhammad Khalid Azeem, Anees ur Rehman Qureshi & Munawar Iqbal. (2019) Loading of Cefixime to pH sensitive chitosan based hydrogel and investigation of controlled release kinetics. International Journal of Biological Macromolecules.
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Min Xiao, Yi Xue, Zhongzhi Wu, Zi-Ning Lei, Jin Wang, Zhe-Sheng Chen & Wei Li. (2019) Design, synthesis and biological evaluation of selective survivin inhibitors. The Journal of Biomedical Research 33:2, pages 82.
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Katarzyna Ratajczak, Bartlomiej E. Krazinski, Anna E. Kowalczyk, Beata Dworakowska, Slawomir Jakiela & Magdalena Stobiecka. (2018) Hairpin–Hairpin Molecular Beacon Interactions for Detection of Survivin mRNA in Malignant SW480 Cells. ACS Applied Materials & Interfaces 10:20, pages 17028-17039.
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Fan Zhang, Jinjin Chu & Fan Wang. (2017) Expression and clinical significance of cyclooxygenase 2 and survivin in human gliomas. Oncology Letters 14:2, pages 1303-1308.
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Eman Alaaeldin, Amr S. Abu Lila, Hidenori Ando, Masakazu Fukushima, Cheng-Long Huang, Hiromi Wada, Hatem A. Sarhan, Khaled A. Khaled & Tatsuhiro Ishida. (2017) Co-administration of liposomal l-OHP and PEGylated TS shRNA-lipoplex: A novel approach to enhance anti-tumor efficacy and reduce the immunogenic response to RNAi molecules. Journal of Controlled Release 255, pages 210-217.
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Majid Zaki Dizaji, Seyed H Ghaffari, Elham Hosseini, Nasrin Alizadeh, Shahrbano Rostami, Majid Momeny, Kamran Alimoghaddam & Ardeshir Ghavamzadeh. (2017) Survivin isoform expression in arsenic trioxide-treated acute promyelocytic leukemia cell line and patients: The odd expression pattern of survivin-2α. Asia-Pacific Journal of Clinical Oncology 13:2, pages e21-e30.
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Jaisy Samuel, Rupinder K. Kanwar, Jagat R. Kanwar, Vikas Khetan & Subramanian Krishnakumar. (2016) A Study of Gene Expression of Survivin, its Antiapoptotic Variants, and Targeting Survivin In Vitro for Therapy in Retinoblastoma. Journal of Pediatric Hematology/Oncology 38:7, pages e230-e242.
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Wei Dai, Quangen Gao, Jianping Qiu, Jianmao Yuan, Guoliang Wu & Genhai Shen. (2015) Quercetin induces apoptosis and enhances 5-FU therapeutic efficacy in hepatocellular carcinoma. Tumor Biology 37:5, pages 6307-6313.
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YINGZHE PAN, YIQIAO XING & HUI WANG. (2015) Expression of survivin in adenoid cystic carcinoma of the lacrimal gland and the effect of intervention with arsenic trioxide in vitro. Experimental and Therapeutic Medicine 10:1, pages 330-334.
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Yugang LiuZhaowei TengYing WangPengfei GaoJunli Chen. (2015) Prognostic Significance of Survivin Expression in Osteosarcoma Patients: A Meta-Analysis. Medical Science Monitor 21, pages 2877-2885.
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Nithya Subramanian, Jagat R. Kanwar, Balachandran Akilandeswari, Rupinder K. Kanwar, Vikas Khetan & Subramanian Krishnakumar. (2015) Chimeric nucleolin aptamer with survivin DNAzyme for cancer cell targeted delivery. Chemical Communications 51:32, pages 6940-6943.
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LI ZHANG, YOUYOU YE, DEJIAN YANG & JIANHUA LIN. (2014) Survivin and vascular endothelial growth factor are associated with spontaneous pulmonary metastasis of osteosarcoma: Development of an orthotopic mouse model. Oncology Letters 8:6, pages 2577-2580.
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Zhao-Shi Bao, Ming-Yang Li, Jia-Yin Wang, Chuan-Bao Zhang, Hong-Jun Wang, Wei Yan, Yan-Wei Liu, Wei Zhang, Ling Chen & Tao Jiang. (2014) Prognostic Value of a Nine-Gene Signature in Glioma Patients Based on mRNA Expression Profiling. CNS Neuroscience & Therapeutics 20:2, pages 112-118.
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Huan-qin Wang, Jian-jun Jin & Jing Wang. (2014) Arctigenin Enhances Chemosensitivity to Cisplatin in Human Nonsmall Lung Cancer H460 Cells through Downregulation of Survivin Expression. Journal of Biochemical and Molecular Toxicology 28:1, pages 39-45.
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Lu Cao, Chunguang Li, Shuwen Shen, Yan Yan, Weidan Ji, Jinghan Wang, Haihua Qian, Xiaoqing Jiang, Zhigang Li, Mengchao Wu, Ying Zhang & Changqing Su. (2013) OCT4 increases BIRC5 and CCND1 expression and promotes cancer progression in hepatocellular carcinoma. BMC Cancer 13:1.
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Swati Dawar, Neha Singh, Rupinder K. Kanwar, Richard Lee Kennedy, Rakesh N. Veedu, Shu-Feng Zhou, Subramanian Krishnakumar, Sarbani Hazra, Sreenivasan Sasidharan, Wei Duan & Jagat R. Kanwar. (2013) Multifunctional and multitargeted nanoparticles for drug delivery to overcome barriers of drug resistance in human cancers. Drug Discovery Today 18:23-24, pages 1292-1300.
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Zhengyu Li, Wenjiao Min & Jinhai Gou. (2013) Knockdown of cyclophilin A reverses paclitaxel resistance in human endometrial cancer cells via suppression of MAPK kinase pathways. Cancer Chemotherapy and Pharmacology 72:5, pages 1001-1011.
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Jian Song, Hong Su, Yang-yang Zhou & Liang-liang Guo. (2013) Prognostic value of survivin expression in breast cancer patients: a meta-analysis. Tumor Biology 34:4, pages 2053-2062.
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Jagat R. Kanwar, Sishir K. Kamalapuram & Rupinder K. Kanwar. (2013) Survivin Signaling in Clinical Oncology: A Multifaceted Dragon. Medicinal Research Reviews 33:4, pages 765-789.
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Beom Seob LeeSoo Hyuk KimTaewon JinEun Young ChoiJaewon OhSungha ParkSang Hak LeeJi Hyung ChungSeok-Min Kang. (2013) Protective Effect of Survivin in Doxorubicin-Induced Cell Death in H9c2 Cardiac Myocytes. Korean Circulation Journal 43:6, pages 400.
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Chin-Sheng Hung, Shen-Fu Lin, Hui-Hsiung Liu, Li-Jen Kuo, Li-Tzu Li, Hou-Yu Su, Phui-Ly Liew, Feng-Yen Lin, Po-Li Wei, Der-Zen Liu & Yu-Jia Chang. (2012) Survivin-mediated Therapeutic Efficacy of Gemcitabine through Glucose-regulated Protein 78 in Hepatocellular Carcinoma. Annals of Surgical Oncology 19:8, pages 2744-2752.
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XIANG-QI CHEN, SHENG YANG, MING-QIANG KANG, ZHI-YING LI, HUI-SHAN LU & TING-YAN LIN. (2012) Survivin expression in human lung cancer and the influence of its downregulation on the biological behavior of human lung cancer cells. Experimental and Therapeutic Medicine 3:6, pages 1010-1014.
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Chi-Tai Yeh, Yerra Koteswara Rao, Min Ye, Wen-Shi Wu, Tung-Chen Chang, Liang-Shun Wang, Chih-Hsiung Wu, Alexander T.H. Wu & Yew-Min Tzeng. (2012) Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging. Toxicology and Applied Pharmacology 261:1, pages 31-41.
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Young Il Kim, Byeong-Cheol Ahn, John A. Ronald, Regina Katzenberg, Abhinav Singh, Ramasamy Paulmurugan, Sunetra Ray, Sanjiv S. Gambhir & Lawrence V. Hofmann. (2012) Intratumoral versus Intravenous Gene Therapy Using a Transcriptionally Targeted Viral Vector in an Orthotopic Hepatocellular Carcinoma Rat Model. Journal of Vascular and Interventional Radiology 23:5, pages 704-711.
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Xiao‐Yuan Chu, Long‐Bang Chen, Jing‐Hua Wang, Quan‐Sheng Su, Ji‐Rong Yang, Yong Lin, Li‐Jun Xue, Xiao‐Bei Liu & Xiao‐Bei Mo. (2011) Overexpression of survivin is correlated with increased invasion and metastasis of colorectal cancer. Journal of Surgical Oncology 105:6, pages 520-528.
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Meena Upadhyaya, Gill Spurlock, Laura Thomas, Nick S. T. Thomas, Mark Richards, Viktor-Felix Mautner, David N. Cooper, Abhijit Guha & Jim Yan. (2012) Microarray-based copy number analysis of neurofibromatosis type-1 (NF1)-associated malignant peripheral nerve sheath tumors reveals a role for Rho-GTPase pathway genes in NF1 tumorigenesis. Human Mutation 33:4, pages 763-776.
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Tomoko Kurita, Hiroto Izumi, Seiji Kagami, Toshinori Kawagoe, Naoyuki Toki, Yusuke Matsuura, Toru Hachisuga & Kimitoshi Kohno. (2012) Mitochondrial transcription factor A regulates BCL2L1 gene expression and is a prognostic factor in serous ovarian cancer. Cancer Science 103:2, pages 239-444.
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Jiamu Du, Alexander E. Kelly, Hironori Funabiki & Dinshaw J. Patel. (2012) Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin. Structure 20:1, pages 185-195.
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C. Di Cresce, R. Figueredo, P. J. Ferguson, M. D. Vincent & J. Koropatnick. (2011) Combining Small Interfering RNAs Targeting Thymidylate Synthase and Thymidine Kinase 1 or 2 Sensitizes Human Tumor Cells to 5-Fluorodeoxyuridine and Pemetrexed. Journal of Pharmacology and Experimental Therapeutics 338:3, pages 952-963.
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Eugene ParkEun Ji GangYao-Te HsiehPaul SchaeferSanna ChaeLars Klemm, Sandra HuantesMignon LohEdward M. ConwayEun-Suk Kang, Hong Hoe KooWolf-Karsten HofmannNora HeisterkampLouis PelusGanesan Keerthivasan, John Crispino, Michael Kahn, Markus Müschen & Yong-Mi Kim. (2011) Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia. Blood 118:8, pages 2191-2199.
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Jagat R. Kanwar, Sishir K. Kamalapuram & Rupinder K. Kanwar. (2011) Targeting survivin in cancer: the cell-signalling perspective. Drug Discovery Today 16:11-12, pages 485-494.
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Jagat R. Kanwar, Ganesh Mahidhara & Rupinder K. Kanwar. (2011) Antiangiogenic therapy using nanotechnological-based delivery system. Drug Discovery Today 16:5-6, pages 188-202.
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