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Novel phosphodiesterase type 5 modulators: a patent survey (2008 – 2010)

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Pages 1631-1641 | Published online: 09 Sep 2011

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Bhuvaneshwar Vaidya, Matthew Pangallo, Gregoire Ruffenach, Christine Marie Cunningham, Jeanette C. Perron, Srikanth Kolluru, Mansoureh Eghbali & Vivek Gupta. (2017) Advances in treatment of pulmonary arterial hypertension: patent review. Expert Opinion on Therapeutic Patents 27:8, pages 907-918.
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Roberto Bruzziches, Davide Francomano, Pietro Gareri, Andrea Lenzi & Antonio Aversa. (2013) An update on pharmacological treatment of erectile dysfunction with phosphodiesterase type 5 inhibitors. Expert Opinion on Pharmacotherapy 14:10, pages 1333-1344.
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Articles from other publishers (16)

Farnoosh Nik-Ahd & Alan W. Shindel. (2022) Pharmacotherapy for Erectile Dysfunction in 2021 and Beyond. Urologic Clinics of North America 49:2, pages 209-217.
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Yurii Gurzhenko. (2021) A Comprehensive Approach in the Treatment of Erectile Dysfunction in Obesity Patients. Health of Man:4, pages 57-71.
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Yurii Gurzhenko. (2021) Study of the Efficiency of Using Type 5 Phosphodiesterase Inhibitors in the Therapy of Ereсtile Dysfunction in Patients with Metabolic Syndrome. Health of Man:3, pages 58-69.
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Jaesung Pyo. (2021) New Metabolites of Udenafil Identified through Liquid Chromatography– Quadrupole Time-of-flight Mass Spectrometry. Current Pharmaceutical Analysis 17:8, pages 1000-1007.
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Hussein O. Ammar, Mina I. Tadros, Nahla M. Salama & Amira M. Ghoneim. (2020) Therapeutic Strategies for Erectile Dysfunction With Emphasis on Recent Approaches in Nanomedicine. IEEE Transactions on NanoBioscience 19:1, pages 11-24.
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Ю. М. Гурженко. (2019) Physophydesterase Inhibitors of 5 Type and Erective Dysfunction. Health of Man:1, pages 64-74.
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Hyang-Ki ChoiEon-Jeong ShimJihong ShonJin Ah JungJong-Lyul GhimJi-Hwa RyuKyun-Seop BaeJae-Gook Shin. (2016) Effects of mirodenafil on the hemodynamics in hypertensive patients taking amlodipine. Translational and Clinical Pharmacology 24:2, pages 90.
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Zhi-wei Gao, Yun-ting Zhu, Ming-ming Yu, Bin Zan, Jia Liu, Yi-fan Zhang, Xiao-yan Chen, Xue-ning Li & Da-fang Zhong. (2015) Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model. Acta Pharmacologica Sinica 36:12, pages 1528-1536.
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Tsutomu Saji, Tomotaka Nakayama, Shinichi Takatsuki, Satoshi Ikehara, Hiromitsu Shimada, Kazuyuki Naoi, Mari Sato & Hiroyuki Matsuura. (2015) The Real World of Medical Treatment of Pulmonary Arterial Hypertension―Small Evidence, but Heavy Cornerstone―. Pediatric Cardiology and Cardiac Surgery 31:4, pages 157-183.
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Zhe Li, Yinuo Wu, Ling-Jun Feng, Ruibo Wu & Hai-Bin Luo. (2014) Ab Initio QM/MM Study Shows a Highly Dissociated S N 2 Hydrolysis Mechanism for the cGMP-Specific Phosphodiesterase-5 . Journal of Chemical Theory and Computation 10:12, pages 5448-5457.
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Rufael Chekol, Olivier Gheysens, Jan Cleynhens, Peter Pokreisz, Greet Vanhoof, Muneer Ahamed, Stefan Janssens, Alfons Verbruggen & Guy Bormans. (2014) Evaluation of PET radioligands for in vivo visualization of phosphodiesterase 5 (PDE5). Nuclear Medicine and Biology 41:2, pages 155-162.
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Jeffrey A. Kyle, Dana A. Brown & Jerame K. Hill. (2013) Avanafil for Erectile Dysfunction. Annals of Pharmacotherapy 47:10, pages 1312-1320.
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M. Ortaç, S. Çayan, M. K. Çalışkan, M. Ö. Yaman, T. M. Okutucu, M. B. Semerci, A. B. Altay, M. D. Balbay, M. F. Özcan & A. Kadıoğlu. (2013) Efficacy and tolerability of udenafil in Turkish men with erectile dysfunction of psychogenic and organic aetiology: a randomized, double‐blind, placebo‐controlled study. Andrology 1:4, pages 549-555.
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JinQiu Yuan, RenJie Zhang, ZuYao Yang, Jack Lee, YaLi Liu, JinHui Tian, XiWen Qin, ZhengJia Ren, Hong Ding, Qing Chen, Chen Mao & JinLing Tang. (2013) Comparative Effectiveness and Safety of Oral Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction: A Systematic Review and Network Meta-analysis. European Urology 63:5, pages 902-912.
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Mehmet Guzeloglu, Koray Aykut, Gökhan Albayrak, Soner Atmaca, Suleyman Oktar, Alper Bagriyanik & Eyup Hazan. (2013) Effect of Tadalafil on Neointimal Hyperplasia in a Rabbit Carotid Artery Anastomosis Model. Annals of Thoracic and Cardiovascular Surgery 19:6, pages 468-474.
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J H Lee, M R Chae, J K Park, J H Jeon & S W Lee. (2012) The effects of the combined use of a PDE5 inhibitor and medications for hypertension, lower urinary tract symptoms and dyslipidemia on corporal tissue tone. International Journal of Impotence Research 24:6, pages 221-227.
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