Advanced search
Publication Cover
Expert Opinion on Investigational Drugs Volume 14, 2005 - Issue 6
Submit an article Journal homepage
113
Views
20
CrossRef citations to date
0
Altmetric
Review

ADAM proteases, ErbB pathways and cancer

Bin-Bing S Zhou Drug Discovery Biology, Incyte Corporation, Experimental Station, Route 141 & Henry Clay Road, Building 400, Wilmington, DE 19880, USA. [email protected]
,
Jordan S Fridman Drug Discovery Biology, Incyte Corporation, Experimental Station, Route 141 & Henry Clay Road, Building 400, Wilmington, DE 19880, USA. [email protected]
,
Xiangdong Liu Drug Discovery Biology, Incyte Corporation, Experimental Station, Route 141 & Henry Clay Road, Building 400, Wilmington, DE 19880, USA. [email protected]
,
Steve M Friedman Drug Discovery Biology, Incyte Corporation, Experimental Station, Route 141 & Henry Clay Road, Building 400, Wilmington, DE 19880, USA. [email protected]
,
Robert C Newton Drug Discovery Biology, Incyte Corporation, Experimental Station, Route 141 & Henry Clay Road, Building 400, Wilmington, DE 19880, USA. [email protected]
&
Peggy A Scherle Drug Discovery Biology, Incyte Corporation, Experimental Station, Route 141 & Henry Clay Road, Building 400, Wilmington, DE 19880, USA. [email protected]
Pages 591-606 | Published online: 11 Jul 2005

Citations (20)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Siavash Foroughi, Jeanne Tie, Peter Gibbs & Antony Wilks Burgess. (2019) Epidermal growth factor receptor ligands: targets for optimizing treatment of metastatic colorectal cancer. Growth Factors 37:5-6, pages 209-225.
Read now
Alessio Giubellino, Terrence R Burke & Donald P Bottaro. (2008) Grb2 signaling in cell motility and cancer. Expert Opinion on Therapeutic Targets 12:8, pages 1021-1033.
Read now

Articles from other publishers (18)

Björn Kruspig, Tiziana Monteverde, Sarah Neidler, Andreas HockEmma KerrColin Nixon, William ClarkAnn Hedley, Sarah Laing, Seth B. Coffelt, John Le Quesne, Craig DickKaren H. VousdenCarla P. MartinsDaniel J. Murphy. (2018) The ERBB network facilitates KRAS-driven lung tumorigenesis. Science Translational Medicine 10:446.
Crossref
Peter J. Dempsey. (2017) Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1864:11, pages 2228-2239.
Crossref
David W. Greening, Shashi K. Gopal, Rommel A. Mathias, Lin Liu, Jingyi Sheng, Hong-Jian Zhu & Richard J. Simpson. (2015) Emerging roles of exosomes during epithelial?mesenchymal transition and cancer progression. Seminars in Cell & Developmental Biology 40, pages 60-71.
Crossref
M. V. Arcidiacono, J. Yang, E. Fernandez & A. Dusso. (2014) The induction of C/EBP  contributes to vitamin D inhibition of ADAM17 expression and parathyroid hyperplasia in kidney disease. Nephrology Dialysis Transplantation 30:3, pages 423-433.
Crossref
Clara L. Sampieri. (2013) Helicobacter pylori and Gastritis: The Role of Extracellular Matrix Metalloproteases, Their Inhibitors, and the Disintegrins and Metalloproteases—A Systematic Literature Review. Digestive Diseases and Sciences 58:10, pages 2777-2783.
Crossref
Rommel A. Mathias, Shashi K. Gopal & Richard J. Simpson. (2013) Contribution of cells undergoing epithelial–mesenchymal transition to the tumour microenvironment. Journal of Proteomics 78, pages 545-557.
Crossref
Alessio Giubellino. 2012. Cell Signaling & Molecular Targets in Cancer. Cell Signaling & Molecular Targets in Cancer 1 22 .
Marcia L. Moss, Gary Powell, Miles A. Miller, Lori Edwards, Bin Qi, Qing-Xiang Amy Sang, Bart De Strooper, Ina Tesseur, Stefan F. Lichtenthaler, Mara Taverna, Julia Li Zhong, Colin Dingwall, Taheera Ferdous, Uwe Schlomann, Pei Zhou, Linda G. Griffith, Douglas A. Lauffenburger, Robert Petrovich & Jörg W. Bartsch. (2011) ADAM9 Inhibition Increases Membrane Activity of ADAM10 and Controls α-Secretase Processing of Amyloid Precursor Protein. Journal of Biological Chemistry 286:47, pages 40443-40451.
Crossref
Gillian Murphy. (2008) The ADAMs: signalling scissors in the tumour microenvironment. Nature Reviews Cancer 8:12, pages 932-941.
Crossref
G Sithanandam & L M Anderson. (2008) The ERBB3 receptor in cancer and cancer gene therapy. Cancer Gene Therapy 15:7, pages 413-448.
Crossref
Anurag Singh, Sreenath V. Sharma & Jeffrey Settleman. 2009. Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response. Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response 103 126 .
Marcia L. Moss, Martha Bomar, Qian Liu, Harvey Sage, Peter Dempsey, Patricia M. Lenhart, Patricia A. Gillispie, Alexander Stoeck, Dirk Wildeboer, Jörg W. Bartsch, Ralf Palmisano & Pei Zhou. (2007) The ADAM10 Prodomain Is a Specific Inhibitor of ADAM10 Proteolytic Activity and Inhibits Cellular Shedding Events. Journal of Biological Chemistry 282:49, pages 35712-35721.
Crossref
Michael F Press & Heinz-Josef Lenz. (2007) EGFR, HER2 and VEGF Pathways. Drugs 67:14, pages 2045-2075.
Crossref
Nancy E. Hynes & Thomas Schlange. (2006) Targeting ADAMS and ERBBs in lung cancer. Cancer Cell 10:1, pages 7-11.
Crossref
Bin-Bing S. Zhou, Michael Peyton, Biao He, Changnian Liu, Luc Girard, Eian Caudler, Yvonne Lo, Frederic Baribaud, Iwao Mikami, Noemi Reguart, Gengjie Yang, Yanlong Li, Wenqing Yao, Kris Vaddi, Adi F. Gazdar, Steven M. Friedman, David M. Jablons, Robert C. Newton, Jordan S. Fridman, John D. Minna & Peggy A. Scherle. (2006) Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell 10:1, pages 39-50.
Crossref
Peng Yang, K. Adam Baker & Theo Hagg. (2006) The ADAMs family: Coordinators of nervous system development, plasticity and repair. Progress in Neurobiology 79:2, pages 73-94.
Crossref
Joaquín Arribas, Joan J. Bech-Serra & Belén Santiago-Josefat. (2006) ADAMs, cell migration and cancer. Cancer and Metastasis Reviews 25:1, pages 57-68.
Crossref
BIN-BING S. ZHOU. (2005) Targeting Ligand Cleavage to Inhibit the ErbB Pathway in Cancer. Annals of the New York Academy of Sciences 1059:1, pages 56-60.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.