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Review

Targeting the c-MET signaling pathway for cancer therapy

, PhD, , PhD, , PhD & , PhD
Pages 997-1011 | Published online: 12 Jun 2008

Keep up to date with the latest research on this topic with citation updates for this article.

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Jiali Xie, Xiaoxuan Zhang, Dan Meng, Yihao Li & Ping Deng. (2023) Identification of potentially high drug-like VEGFR2/c-Met dual-target type II kinase inhibitors with symmetric skeletons based on structural screening. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-19.
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Cilong Chu, Zixuan Rao, Qingshan Pan & Wufu Zhu. (2022) An updated patent review of small-molecule c-Met kinase inhibitors (2018-present). Expert Opinion on Therapeutic Patents 32:3, pages 279-298.
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Simon Vyse & Paul H Huang. (2022) Amivantamab for the treatment of EGFR exon 20 insertion mutant non-small cell lung cancer. Expert Review of Anticancer Therapy 22:1, pages 3-16.
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Ryo Fujita, Vincent Blot, Eley Wong, Christine Stewart, Vincent Lieuw, Robyn Richardson, Ammar Banah, Jose Villicana, Anjuli Timmer, Julia Coronella, Roland Newman & Marco Gymnopoulos. (2020) A novel non-agonist c-Met antibody drug conjugate with superior potency over a c-Met tyrosine kinase inhibitor in c-Met amplified and non-amplified cancers. Cancer Biology & Therapy 21:6, pages 549-559.
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Bianca M. Liederer, Xingrong Liu, Leonid M. Berezhkovskiy, Gary Cain, Xiao Ding, John Gaudino, Robert Kaus, Emile G. Plise, Daniel P. Sutherlin & Eric B. Harstad. (2012) Preclinical stereoselective disposition and toxicokinetics of two novel MET inhibitors. Xenobiotica 42:5, pages 456-465.
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Andreas Varkaris, Paul G Corn, Sanchaika Gaur, Farshid Dayyani, Christopher J Logothetis & Gary E Gallick. (2011) The role of HGF/c-Met signaling in prostate cancer progression and c-Met inhibitors in clinical trials. Expert Opinion on Investigational Drugs 20:12, pages 1677-1684.
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Xiangdong Liu, Robert C Newton & Peggy A Scherle. (2011) Development of c-MET pathway inhibitors. Expert Opinion on Investigational Drugs 20:9, pages 1225-1241.
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John Porter. (2010) Small molecule c-Met kinase inhibitors: a review of recent patents. Expert Opinion on Therapeutic Patents 20:2, pages 159-177.
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