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Marco Greco, Gaia Varriale, Giangennaro Coppola, Francesca Operto, Alberto Verrotti & Maria Laura Iezzi. (2018) Investigational small molecules in phase II clinical trials for the treatment of epilepsy. Expert Opinion on Investigational Drugs 27:12, pages 971-979.
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Christopher R. Cederroth, Jonas Dyhrfjeld-Johnsen & Berthold Langguth. (2018) An update: emerging drugs for tinnitus. Expert Opinion on Emerging Drugs 23:4, pages 251-260.
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Takahisa Hanada. (2014) The AMPA receptor as a therapeutic target in epilepsy: preclinical and clinical evidence. Journal of Receptor, Ligand and Channel Research 7, pages 39-50.
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Articles from other publishers (29)
Marina N. Vukolova, Laura Y. Yen, Margarita I. Khmyz, Alexander I. Sobolevsky & Maria V. Yelshanskaya. (2023) Parkinson’s disease, epilepsy, and amyotrophic lateral sclerosis—emerging role of AMPA and kainate subtypes of ionotropic glutamate receptors. Frontiers in Cell and Developmental Biology 11.
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Crossref
Svetlana O. Baykova, Kirill K. Geyl, Sergey V. Baykov & Vadim P. Boyarskiy. (2023) Synthesis of 3-(Pyridin-2-yl)quinazolin-2,4(1H,3H)-diones via Annulation of Anthranilic Esters with N-pyridyl Ureas. International Journal of Molecular Sciences 24:8, pages 7633.
Crossref
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Tsang-Shan Chen, Tzu-Hsin Huang, Ming-Chi Lai & Chin-Wei Huang. (2023) The Role of Glutamate Receptors in Epilepsy. Biomedicines 11:3, pages 783.
Crossref
Crossref
Paulina Chałupnik & Ewa Szymańska. (2023) Kainate Receptor Antagonists: Recent Advances and Therapeutic Perspective. International Journal of Molecular Sciences 24:3, pages 1908.
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Iwona E. Głowacka, Katarzyna Gawron, Dorota G. Piotrowska, Mirthe Graus, Graciela Andrei, Dominique Schols, Robert Snoeck, Anita Camps, Emiel Vanhulle & Kurt Vermeire. (2023) Design and synthesis of a new series of hybrids of functionalised N1-[(1H-1,2,3-triazol-4-yl)methyl]quinazoline-2,4-dione with antiviral activity against Respiratory Syncytial Virus. Antiviral Research 209, pages 105518.
Crossref
Crossref
Arghya Ghosh, Sayan Shee & Akkattu T. Biju. (2022) A Benzannulation Strategy for Rapid Access to Quinazoline-2,4-diones via Oxidative N-Heterocyclic Carbene Catalysis. Organic Letters 24:14, pages 2772-2777.
Crossref
Crossref
K. Y. Kalitin, A. A. Spasov, O. Y. Mukha, G. V. Pridvorov & V. A. Lipatov. (2022) Pharmacological Targets and Mechanisms of Action of Antipsychotic Substances in the Context of the Neurochemical Theory of the Pathogenesis of Schizophrenia. Neuroscience and Behavioral Physiology 52:1, pages 108-123.
Crossref
Crossref
Kasper B. Hansen, Lonnie P. Wollmuth, Derek Bowie, Hiro Furukawa, Frank S. Menniti, Alexander I. Sobolevsky, Geoffrey T. Swanson, Sharon A. Swanger, Ingo H. Greger, Terunaga Nakagawa, Chris J. McBain, Vasanthi Jayaraman, Chian-Ming Low, Mark L. Dell’Acqua, Jeffrey S. Diamond, Chad R. Camp, Riley E. Perszyk, Hongjie Yuan & Stephen F. Traynelis. (2022) Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels. Pharmacological Reviews 73:4, pages 1469-1658.
Crossref
Crossref
Klaus Kucher, Donald Johns, Frank Wagner, Khalid Abd-Elaziz, Caroline Derne, Oleksandr Sverdlov, Christian U. Pfister & Berthold Langguth. 2021. Tinnitus - An Interdisciplinary Approach Towards Individualized Treatment: From Heterogeneity to Personalized Medicine. Tinnitus - An Interdisciplinary Approach Towards Individualized Treatment: From Heterogeneity to Personalized Medicine
423
440
.
Tobias Kleinjung & Berthold Langguth. (2020) Avenue for Future Tinnitus Treatments. Otolaryngologic Clinics of North America 53:4, pages 667-683.
Crossref
Crossref
Jiahui Chen, Jiefeng Gan, Jiyun Sun, Zhen Chen, Hualong Fu, Jian Rong, Xiaoyun Deng, Jingjie Shang, Jian Gong, Tuo Shao, Lee Collier, Lu Wang, Hao Xu & Steven H. Liang. (2020) Radiosynthesis and preliminary evaluation of 11C-labeled 4-cyclopropyl-7-(3-methoxyphenoxy)-3,4-dihydro-2H-benzo[e] [1,2,4] thiadiazine 1,1-dioxide for PET imaging AMPA receptors. Tetrahedron Letters 61:12, pages 151635.
Crossref
Crossref
Yi Wang & Zhong Chen. (2019) An update for epilepsy research and antiepileptic drug development: Toward precise circuit therapy. Pharmacology & Therapeutics 201, pages 77-93.
Crossref
Crossref
Galal H. Elgemeie, Rasha A. Azzam & Rasha E. Elsayed. (2019) Sulfa drug analogs: new classes of N-sulfonyl aminated azines and their biological and preclinical importance in medicinal chemistry (2000–2018). Medicinal Chemistry Research 28:8, pages 1099-1131.
Crossref
Crossref
Hiroshi InamiJun-ichi ShishikuraTomoyuki YasunagaMasaaki HiranoTakenori KimuraHiroshi YamashitaKazushige OhnoShuichi Sakamoto. (2019) Synthesis and Pharmacological Evaluation of 3-[(4-Oxo-4<i>H</i>-pyrido[3,2-<i>e</i>][1,3]thiazin-2-yl)(phenyl)amino]propanenitrile Derivatives as Orally Active AMPA Receptor Antagonists. Chemical and Pharmaceutical Bulletin 67:7, pages 699-706.
Crossref
Crossref
Zhen Chen, Wakana Mori, Xiaofei Zhang, Tomoteru Yamasaki, Patrick J. Dunn, Genwei Zhang, Hualong Fu, Tuo Shao, Yiding Zhang, Akiko Hatori, Longle Ma, Masayuki Fujinaga, Lin Xie, Xiaoyun Deng, Hua Li, Qingzhen Yu, Jian Rong, Lee Josephson, Jun-An Ma, Yihan Shao, Susumu Tomita, Ming-Rong Zhang & Steven H. Liang. (2018) Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein. European Journal of Medicinal Chemistry 157, pages 898-908.
Crossref
Crossref
David Orain, Engin Tasdelen, Samuel Haessig, Manuel Koller, Anne Picard, Celine Dubois, Kurt Lingenhoehl, Sandrine Desrayaud, Phillip Floersheim, David Carcache, Stephan Urwyler, Joerg Kallen & Henri Mattes. (2017) Design and Synthesis of Selurampanel, a Novel Orally Active and Competitive AMPA Receptor Antagonist. ChemMedChem 12:3, pages 197-201.
Crossref
Crossref
Ambica Golyala & Patrick Kwan. (2017) Drug development for refractory epilepsy: The past 25 years and beyond. Seizure 44, pages 147-156.
Crossref
Crossref
T. Kurokawa, Y. Kazuta & T. Watanabe. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III
1
19
.
Gengyang Yuan, Graham B. Jones, Neil Vasdev & Steven H. Liang. (2016) Radiosynthesis and preliminary PET evaluation of 18 F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors. Bioorganic & Medicinal Chemistry Letters 26:19, pages 4857-4860.
Crossref
Crossref
Harjeet Kaur, Baldeep Kumar & Bikash Medhi. (2016) Antiepileptic drugs in development pipeline: A recent update. eNeurologicalSci 4, pages 42-51.
Crossref
Crossref
Jing An, Howard Alper & André M. Beauchemin. (2016)
Copper-Catalyzed Cascade Substitution/Cyclization of
N
-Isocyanates: A Synthesis of 1-Aminobenzimidazolones
. Organic Letters 18:14, pages 3482-3485.
Crossref
Crossref
Gaetano Zaccara & Dieter Schmidt. (2016) Do traditional anti-seizure drugs have a future? A review of potential anti-seizure drugs in clinical development. Pharmacological Research 104, pages 38-48.
Crossref
Crossref
Norihito Oi, Masaki Tokunaga, Michiyuki Suzuki, Yuji Nagai, Yosuke Nakatani, Noboru Yamamoto, Jun Maeda, Takafumi Minamimoto, Ming-Rong Zhang, Tetsuya Suhara & Makoto Higuchi. (2015) Development of Novel PET Probes for Central 2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic Acid Receptors. Journal of Medicinal Chemistry 58:21, pages 8444-8462.
Crossref
Crossref
Norman Delanty & H. Steve White. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy
701
708
.
Dorotheé Kasteleijn-Nolst Trenité, Christian Brandt, Thomas Mayer, Felix Rosenow, Bernd Schmidt, Bernhard J. Steinhoff, Anne Gardin, Georges Imbert, Donald Johns, Alexandros Sagkriotis & Klaus Kucher. (2015) Dose-dependent suppression of human photoparoxysmal response with the competitive AMPA/kainate receptor antagonist BGG492: Clear PK/PD relationship. Epilepsia 56:6, pages 924-932.
Crossref
Crossref
Bernhard J. Steinhoff. (2015) The AMPA receptor antagonist perampanel in the adjunctive treatment of partial-onset seizures: clinical trial evidence and experience. Therapeutic Advances in Neurological Disorders 8:3, pages 137-147.
Crossref
Crossref
Ming Li, Fenghe Niu, Xilin Zhu, Xiaopan Wu, Ning Shen, Xiaozhong Peng & Ying Liu. (2015) PRRT2 Mutant Leads to Dysfunction of Glutamate Signaling. International Journal of Molecular Sciences 16:12, pages 9134-9151.
Crossref
Crossref
Hiroshi Inami, Jun-ichi Shishikura, Tomoyuki Yasunaga, Kazushige Ohno, Hiroshi Yamashita, Kota Kato & Shuichi Sakamoto. (2015) Synthesis, structure–activity relationships, and anticonvulsant activities of 2-amino-4H-pyrido[3,2-e][1,3]thiazin-4-one derivatives as orally active AMPA receptor antagonists. Bioorganic & Medicinal Chemistry 23:8, pages 1788-1799.
Crossref
Crossref
Tae Yeon Kim, Takuro Yoshimoto, Yo Aoyama, Kimie Niimi, Eiki Takahashi & Chitoshi Itakura. (2014) Age-dependent kainate sensitivity in heterozygous rolling Nagoya Cav2.1 channel mutant mice. Pharmacology Biochemistry and Behavior 124, pages 250-259.
Crossref
Crossref