Bibliography
- Kwan P, Arzimanoglou A, Berg AT, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc task force of the ILAE commission on therapeutic strategies. Epilepsia 2010;51(1):7-26
- Steinhoff BJ, Ben-Menachem E, Ryvlin P, et al. Efficacy and safety of adjunctive perampanel for the treatment of refractory partial seizures. Epilepsia 2013;54(8):1481-9
- Rogawski MA, Hanada T. Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist. Acta Neurol Scand 2013;127(Suppl 197):19-24
- Rogawski MA. AMPA receptors as a molecular target in epilepsy therapy. Acta Neurol Scand 2013;127(Suppl 197):9-18
- Rajasekaran K, Todorovic M, Kapur J. Calcium-permeable AMPA receptors are expressed in a rodent model of status epilepticus. Ann Neurol 2012;72:91-102
- Li H-B, Matsumoto K, Tohda M, et al. NMDA- but not AMPA –receptor antagonists augment scopolamine-induced spatial cognitive deficit of rats in a radial maze task. Brain Res 1996;725:268-71
- Tomita S, Adesnik H, Sekiguchi M, et al. Stargazin modulates AMPA gating and trafficking by distinct domains. Nature 2005;435(7045):1052-8
- Koller M, Lingenhoehl K, Schmutz M, et al. Quinazolinedione sulfonamides: a novel class of competitive AMPA receptor antagonists with oral activity. Bioorg Med Chem Lett 2011;21:3358-61
- Auberson YP. BGG492, a competitive AMPA/kainate antagonist for the treatment of epilepsy. Presented at the European Federation for Medicinal Chemistry, 21st International Symposium on Medicinal Chemistry; 5 – 9 September 2013; Brussels, Belgium
- Mula M. Emerging drugs for focal epilepsy. Expert Opin Emerg Drugs 2013;18(1):87-95
- Russo E, Gitto R, Citraro R, et al. New AMPA antagonists in epilepsy. Expert Opin. Invest Drugs 2012; [Epub ahead of print]
- BGG492. Accessed from www.clinicaltrials.gov [Accessed 11 July 2013]
- Novartis Clinical Trials Database. Accessed from http://www.novctrd.com/ctrdWebApp/clinicaltrialrepository/public/login.jsp [Accessed 11 July 2013]
- Elger C, Rademacher M, Brandt C, et al. A double-blind, placebo controlled, trial of BGG492 in patients undergoing presurgical evaluation of partial seizures [abstract]. Neurology 2011;76(9):A616
- Chappell AS, Sander JWS, Brodie MJ, et al. A crossover, add-on trial of talampanel in patients with refractory partial seizures. Neurology 2002;58(11):1680-2
- French J, Faught E. Rational polytherapy. Epilepsia 2009;50(Suppl 8):63-681
- Russo I, Bonini D, La Via L, et al. AMPA receptor properties are modulated in the early stages following pilocarpine-induced status epilepticus. Neuromol Med 2013;15:324-38