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Expert Opinion on Investigational Drugs Volume 25, 2016 - Issue 5
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Review

Investigational drugs for fracture healing: preclinical & clinical data

Michail E. KlontzasBiological Systems Engineering Laboratory, Department of Chemical Engineering, Imperial College London, London, UK
,
Eustathios I. KenanidisAcademic Orthopaedic Unit, Aristotle University Medical School, Thessaloniki, Greece
,
Robert J. MacFarlaneBiological Systems Engineering Laboratory, Department of Chemical Engineering, Imperial College London, London, UK
,
Theodoros MichailAcademic Orthopaedic Unit, Aristotle University Medical School, Thessaloniki, Greece
,
Michael E. PotoupnisAcademic Orthopaedic Unit, Aristotle University Medical School, Thessaloniki, Greece
,
Manolis HeliotisDepartment of Oral and Maxillofacial Surgery, London North West Healthcare NHS Trust, Northwick Park Hospital, London, UK
,
Athanasios MantalarisBiological Systems Engineering Laboratory, Department of Chemical Engineering, Imperial College London, London, UK
&
Eleftherios TsiridisAcademic Orthopaedic Unit, Aristotle University Medical School, Thessaloniki, Greece;Department of Surgery and Cancer, Division of Surgery, Imperial College London, London, UKCorrespondence[email protected]
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Pages 585-596 | Received 06 Jan 2016, Accepted 01 Mar 2016, Published online: 28 Mar 2016

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Ke Chen, Hui Gao & Yongchang Yao. (2022) Prospects of cell chemotactic factors in bone and cartilage tissue engineering. Expert Opinion on Biological Therapy 22:7, pages 883-893.
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Tsung-Kun Lin, Yi-Sheng Liou, Ching-Heng Lin, Pesus Chou & Gwo-Ping Jong. (2018) High-potency statins but not all statins decrease the risk of new-onset osteoporotic fractures: a nationwide population-based longitudinal cohort study. Clinical Epidemiology 10, pages 159-165.
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Michail E. Klontzas, Supachai Reakasame, Raquel Silva, Jose C.F. Morais, Spyros Vernardis, Robert J. MacFarlane, Manolis Heliotis, Eleftherios Tsiridis, Nicki Panoskaltsis, Aldo R. Boccaccini & Athanasios Mantalaris. (2019) Oxidized alginate hydrogels with the GHK peptide enhance cord blood mesenchymal stem cell osteogenesis: A paradigm for metabolomics-based evaluation of biomaterial design. Acta Biomaterialia 88, pages 224-240.
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Ekaterina V. Zubareva, Sergey V. Nadezhdin, Yuriy E. Burda, Natalia A. Nadezhdina & Anastasia S. Gashevskaya. (2019) Pleiotropic effects of Erythropoietin. Influence of Erythropoietin on processes of mesenchymal stem cells differentiation. Research Results in Pharmacology 5:1, pages 53-66.
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Kathak Vachhani, Cari Whyne, Yufa Wang, David M. Burns & Diane Nam. (2017) Low‐dose lithium regimen enhances endochondral fracture healing in osteoporotic rodent bone. Journal of Orthopaedic Research 36:6, pages 1783-1789.
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B. Salmon, B. Liu, E. Shen, T. Chen, J. Li, M. Gillette, R. C. Ransom, M. Ezran, C. A. Johnson, A. B. Castillo, W. J. Shen, F. B. Kraemer, A. A. Smith & J. A. Helms. (2017) WNT-activated bone grafts repair osteonecrotic lesions in aged animals. Scientific Reports 7:1.
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I. ZOFKOVA & J. BLAHOS. (2017) New Molecules Modulating Bone Metabolism – New Perspectives in the Treatment of Osteoporosis. Physiological Research, pages S341-S347.
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Michail E. KlontzasSpyros I. VernardisManolis HeliotisEleftherios TsiridisAthanasios Mantalaris. (2017) Metabolomics Analysis of the Osteogenic Differentiation of Umbilical Cord Blood Mesenchymal Stem Cells Reveals Differential Sensitivity to Osteogenic Agents. Stem Cells and Development 26:10, pages 723-733.
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